Title: Isla del Rey Pet-friendly Vacations 2026 | Expedia.com

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# Isla del Rey Pet-friendly Vacations

## Book a Pet-friendly Hotel + Flight or Car together to unlock savings

## Top Pet-friendly vacation packages in Isla del Rey

Price found within the past 48 hours. Click for updated prices.

![Casa Blanca](https://images.trvl-media.com/lodging/106000000/105820000/105811400/105811314/5298e308_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Casa Blanca

$499

per person

May 4 - May 11

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

4/10 (1 review)

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,208

per person

Apr 29 - May 5

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast.

Reviewed on Feb 24, 2026

![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Yoo by Wynwood House

Calidonia

$1,225

per person

Apr 29 - May 5

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.2/10 Wonderful! (5 reviews)

Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.

Reviewed on Jul 26, 2025

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Megapolis Hotel Panamá

San Francisco

$1,149

per person

May 8 - May 13

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was amazing.

Reviewed on Feb 24, 2026

Don't see what you're looking for?

See all available trips from Columbus to Isla del Rey

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## 5\* Pet-friendly vacations in Isla del Rey

Price found within the past 48 hours. Click for updated prices.

![Renaissance Panama City Hotel ](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d8dfdd09_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Renaissance Panama City Hotel 

Bella Vista

$827

per person

Apr 29 - May 5

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (85 reviews)

The King Suite was exceptionally spacious and thoughtfully prepared with everything needed for a comfortable and enjoyable stay. While the hotel itself was excellent, it was truly the staff who made this experience outstanding. Housekeeping was efficient and respectful of our privacy, conveniently servicing the room while we were out and consistently restocking supplies without ever needing reminders. The front desk team—particularly David and Edgardo—were incredibly helpful, professional, and welcoming throughout our stay. David, in particular, enhanced our experience with outstanding restaurant recommendations, assistance with reservations, car service arrangements, and patiently answering our many questions. His attention to detail and commitment to guest satisfaction made a meaningful difference. The morning breakfast and Executive Lounge offered delicious food and beverages each day, adding an extra level of comfort and convenience. The pool area provided a relaxing, private spa-like atmosphere that we thoroughly enjoyed. I look forward to returning and sincerely thank the entire team for delivering exceptional service from start to finish.

Reviewed on Feb 24, 2026

![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Waldorf Astoria Panama

Bella Vista

$1,263

per person

Apr 29 - May 6

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

9/10 Wonderful! (1,001 reviews)

The hotel was wonderful. The entire hotel was clean, staff welcoming especially security employee Flash. The breakfast buffet was great and it was so nice that Divney the receptionist remembered our names each day. My overall stay was great and I would highly recommend this hotel to anyone visiting Panama.

Reviewed on Feb 23, 2026

![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/bd071da6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel La Compania Del Valle

$1,229

per person

Apr 21 - Apr 27

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

9.8/10 Exceptional! (54 reviews)

Modern beautiful property, complimentary handmade cocktails from 5pm to 7pm

Reviewed on Feb 19, 2026

Don't see what you're looking for?

See all available trips from Columbus to Isla del Rey

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## 3 Night Pet-friendly vacations in Isla del Rey

Price found within the past 48 hours. Click for updated prices.

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Megapolis Hotel Panamá

San Francisco

$863

per person

May 1 - May 4

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was amazing.

Reviewed on Feb 24, 2026

![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$1,384

per person

Apr 2 - Apr 5

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

9.8/10 Exceptional! (24 reviews)

Beautiful apartment definitely recommend staying here if you are coming to Panama

Reviewed on Nov 29, 2025

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

$874

per person

May 1 - May 4

found 11 hours ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast.

Reviewed on Feb 24, 2026

Don't see what you're looking for?

See all available trips from Columbus to Isla del Rey

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## 4 Night Pet-friendly vacations in Isla del Rey

Price found within the past 48 hours. Click for updated prices.

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

$562

per person

Apr 1 - Apr 5

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Mahogany Suites

$712

per person

Mar 31 - Apr 4

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

10/10 Exceptional! (1 review)

Excellent apartment on a golf resort. 5 Star.

Reviewed on Jan 28, 2026

![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$2,056

per person

Apr 2 - Apr 6

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

9.8/10 Exceptional! (24 reviews)

Beautiful apartment definitely recommend staying here if you are coming to Panama

Reviewed on Nov 29, 2025

Don't see what you're looking for?

See all available trips from Columbus to Isla del Rey

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## Top Pet-friendly Isla del Rey Hotels

![Bodhi Basecamp at Kalu Yala](https://images.trvl-media.com/lodging/30000000/29310000/29300900/29300844/907277e3_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Bodhi Basecamp at Kalu Yala

Kalu Yala San Miguel San Miguel Panama

- 33 min drive from Playa Ejecutiva

Stay at this hotel in San Miguel. Enjoy free parking, a garden, and a picnic area.

[](https://expedia.com/San-Miguel-Hotels-Bodhi-Basecamp-At-Kalu-Yala.h29300844.Hotel-Information)

[See all 29 properties in Isla del Rey](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&regionId=6336628)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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[Flights to Isla del Rey

](https://expedia.com/Cheap-Flights-To-Isla-Del-Rey.d6336628.Travel-Guide-Flights)[

Isla del Rey Hotels

](https://expedia.com/Isla-Del-Rey-Hotels.d6336628.Travel-Guide-Hotels)[

Vacation Rentals in Isla del Rey

](https://expedia.com/Isla-Del-Rey-Vacation-Rentals.d6336628.Travel-Guide-VacationRentals)[

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\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.