Title: Isla del Rey Pet-friendly Vacations 2026 | Expedia.com ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla del Rey Pet-friendly Vacations ## Book a Pet-friendly Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Pet-friendly vacation packages in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Casa Blanca](https://images.trvl-media.com/lodging/106000000/105820000/105811400/105811314/5298e308_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Blanca $499 per person May 4 - May 11 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 4/10 (1 review) ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,208 per person Apr 29 - May 5 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast. Reviewed on Feb 24, 2026 ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia $1,225 per person Apr 29 - May 5 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on Jul 26, 2025 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $1,149 per person May 8 - May 13 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was amazing. Reviewed on Feb 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Pet-friendly vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $844 per person May 8 - May 13 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) 3rd time there. Love it Reviewed on Feb 24, 2026 ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/bd071da6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Compania Del Valle $1,229 per person Apr 21 - Apr 27 found 1 day ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9.8/10 Exceptional! (54 reviews) Modern beautiful property, complimentary handmade cocktails from 5pm to 7pm Reviewed on Feb 19, 2026 ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### JW Marriott Panama San Francisco $912 per person Apr 2 - Apr 6 found 2 days ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,003 reviews) Great breakfast, service cleanliness. Reviewed on Feb 21, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Pet-friendly vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $863 per person May 1 - May 4 found 24 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was amazing. Reviewed on Feb 24, 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo Save 100% on your flight $1,384 per person Apr 2 - Apr 5 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on Nov 29, 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $874 per person May 1 - May 4 found 9 hours ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast. Reviewed on Feb 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Pet-friendly vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B $562 per person Apr 1 - Apr 5 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (60 reviews) We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time. Reviewed on Jan 22, 2026 ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $712 per person Mar 31 - Apr 4 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on Jan 28, 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo Save 100% on your flight $2,056 per person Apr 2 - Apr 6 found 1 day ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on Nov 29, 2025 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-25/2026-04-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Top Pet-friendly Isla del Rey Hotels ![Bodhi Basecamp at Kalu Yala](https://images.trvl-media.com/lodging/30000000/29310000/29300900/29300844/907277e3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Bodhi Basecamp at Kalu Yala Kalu Yala San Miguel San Miguel Panama - 33 min drive from Playa Ejecutiva Stay at this hotel in San Miguel. Enjoy free parking, a garden, and a picnic area. [](https://expedia.com/San-Miguel-Hotels-Bodhi-Basecamp-At-Kalu-Yala.h29300844.Hotel-Information) [See all 29 properties in Isla del Rey](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6336628) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app