Roxana Vacations from $309

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Your Roxana Vacation

Let our vacation packages to Roxana inspire your next escape. There's tons to love about this exciting city, starting with the neighborhood of Old Jamestown, which is great for nature and walking. Fill your free time with tours of Fast Eddies Bon Air, Robert Wadlow Statue and Lewis and Clark Interpretive Center, some of the top attractions you should see during your trip to Roxana. Your dream Roxana vacation is a few clicks away. Search hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Roxana vacation packages

Price found within the past 48 hours. Click for updated prices.
The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $454, price is now $309 per person
$309
per person
Sep 4 - Sep 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,005 reviews)

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $889, price is now $487 per person
$487
per person
Sep 3 - Sep 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,668 reviews)

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

3 out of 5
Save 100% on your flight
Price was $986, price is now $583 per person
$583
per person
Sep 6 - Sep 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (261 reviews)

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

2 out of 5
Save 100% on your flight
Price was $934, price is now $564 per person
$564
per person
Sep 27 - Oct 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
10/10 Exceptional! (1 review)
The property was excellent, and the home was very warm and welcoming.

Reviewed on Jun 25, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
Save 100% on your flight
Price was $810, price is now $537 per person
$537
per person
Sep 10 - Sep 16
found 19 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
7.4/10 Good! (1,259 reviews)
The grounds are beautiful. Unfortunately we did not get the room I reserved for my family.

Reviewed on Aug 3, 2026

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Stay near popular Roxana attractions

Wood River Refinery History Museum

You can spend an afternoon studying the exhibits at Wood River Refinery History Museum in Roxana.
See properties

Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $158 total per night from Aug 28 to Aug 29
$158 total
Aug 28 - Aug 29
Total with taxes and fees
8.6/10 Excellent! (4,174 reviews)
"Super clean and easy check in."

Reviewed on Aug 4, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$91 nightly
The price is $106 total per night from Aug 30 to Aug 31
$106 total
Aug 30 - Aug 31
Total with taxes and fees
9/10 Wonderful! (3,325 reviews)
"Liked something’s was in walking distance and things I didn’t like no restaurant and bar elevator stop working and staff seemed not to care"

Reviewed on Aug 4, 2026

Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $130 total per night from Aug 28 to Aug 29
$130 total
Aug 28 - Aug 29
Total with taxes and fees
8.4/10 Very Good! (1,128 reviews)
"Timely"

Reviewed on Aug 4, 2026

Renaissance St. Louis Airport Hotel
See all 1,531 properties in Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Roxana Vacation Packages

Roxana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
1,500
Top Sights
Splash City Family Waterpark, National Great Rivers Museum and Gateway Fun Park

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Frequently asked questions

How much does a Roxana vacation package cost?
You'll find cheap prices from $309 on Expedia for your Roxana escape. However, a range of factors like the hotel choice, length of stay and season will influence how much your vacation to Roxana costs.
What are the cheapest months to go to Roxana?
If you're looking to book a cheap Roxana vacation package, consider planning a trip in November, December and January. You're likely to find lower prices on accommodations and flights during these months — perfect for a budget-friendly getaway.
How many days is enough for Roxana?
With a well-organized travel plan, you can easily visit the main Roxana sights in a few days. But if you'd like to venture off the beaten track or go on day tours, think about booking your Roxana vacation for longer.
How to find the best Roxana package deals?
Use Expedia's filter tool to help you find some terrific Roxana package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or search for Roxana package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Roxana vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component separately. And you'll still get the flexibility to create a customized Roxana vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Roxana?
If you've got your Roxana vacation dates confirmed, book as early as you can to grab some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Roxana vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Roxana vacation over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.