Photo by Abby Fieldhouse

Find hotels in Cherokee Seneca, Louisville from $76

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Discover 1,854 Cherokee Seneca hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites Louisville North
Lobby
Drury Inn & Suites Louisville North
3.0 star property
9.6 out of 10, Exceptional, (1002)
"I liked the convenience of this property 5 star for the cleanliness and the food was about a 4 star. The things I didn't care for was the pool time should have been extended for the adults because the pool was full of kids up until closing Not getting the chance to actually enjoy the pool. "
The price is $108
$127 total
includes taxes & fees
May 28 - May 29
Drury Inn & Suites Louisville North
Hyatt House Louisville East
Terrace/patio
Hyatt House Louisville East
2.0 star property
9.6 out of 10, Exceptional, (802)
"Nice suite plenty of space "
The price is $128
$150 total
includes taxes & fees
May 25 - May 26
Hyatt House Louisville East
Hilton Garden Inn Jeffersonville Louisville North
Exterior
Hilton Garden Inn Jeffersonville Louisville North
3.0 star property
9.6 out of 10, Exceptional, (150)
"Wonderful newly renovated motel by Kentucky Lake"
The price is $133
$150 total
includes taxes & fees
Jun 1 - Jun 2
Hilton Garden Inn Jeffersonville Louisville North
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
The Grady
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady
4.0 star property
9.4 out of 10, Exceptional, (618)
"Was very okay "
The price is $224
$264 total
includes taxes & fees
May 27 - May 28
The Grady
Homewood Suites by Hilton Louisville Downtown, KY
Exterior
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.2 out of 10, Wonderful, (865)
"Great, clean, friendly, good breakfast"
The price is $123
$145 total
includes taxes & fees
May 28 - May 29
Homewood Suites by Hilton Louisville Downtown, KY
21c Museum Hotel Louisville
Front of property
21c Museum Hotel Louisville
4.5 star property
9.2 out of 10, Wonderful, (1000)
"Excellent location, friendly staff, great rooms"
The price is $179
$211 total
includes taxes & fees
May 27 - May 28
21c Museum Hotel Louisville
Moxy Louisville Downtown
Breakfast, lunch, dinner served; Mexican cuisine
Moxy Louisville Downtown
3.5 star property
9.2 out of 10, Wonderful, (492)
"Great vibe and experience. Amazing staff. "
The price is $128
$151 total
includes taxes & fees
May 27 - May 28
Moxy Louisville Downtown
AC Hotel Louisville Downtown
Property amenity
AC Hotel Louisville Downtown
3.5 star property
9.2 out of 10, Wonderful, (479)
"Highly recommend! Great hotel, quiet room, perfect beds! Many restaurants and bars near by. We will go back!"
The price is $135
$159 total
includes taxes & fees
May 27 - May 28
AC Hotel Louisville Downtown
Aloft Louisville East
Indoor pool
Aloft Louisville East
3.0 star property
9.2 out of 10, Wonderful, (812)
"Great property, spacious rooms! Staff was really kind and helpful! Seems that the walls are a bit thin tho, so we did use earplugs. "
The price is $111
$130 total
includes taxes & fees
May 22 - May 23
Aloft Louisville East
Tru by Hilton Louisville East
Exterior
Tru by Hilton Louisville East
2.5 star property
9.2 out of 10, Wonderful, (370)
"Great stay! Clean and very friendly staff. "
The price is $121
$142 total
includes taxes & fees
May 27 - May 28
Tru by Hilton Louisville East
Hampton Inn Louisville East/Hurstbourne
Terrace/patio
Hampton Inn Louisville East/Hurstbourne
2.5 star property
9.2 out of 10, Wonderful, (328)
"Hotel was clean, spacious with areas for families to hang out inside and outside. Only complaint was we booked 2 queens and when we arrived in room the beds were double. It was the same with 3 other families that booked here through our group. Beds were small and uncomfortable. Otherwise property was fantastic. "
The price is $129
$152 total
includes taxes & fees
May 26 - May 27
Hampton Inn Louisville East/Hurstbourne
Omni Louisville Hotel
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel
4.0 star property
9.0 out of 10, Wonderful, (1113)
"Nice staff. Very clean. Very efficiently run."
The price is $212
$249 total
includes taxes & fees
May 23 - May 24
Omni Louisville Hotel
The Brown Hotel
Lobby
The Brown Hotel
4.5 star property
9.0 out of 10, Wonderful, (1002)
"I like the vibes"
The price is $174
$204 total
includes taxes & fees
May 23 - May 24
The Brown Hotel
Aloft Louisville Downtown
Reception
Aloft Louisville Downtown
3.0 star property
9.0 out of 10, Wonderful, (1002)
"We have stayed here before and will definitely be back. The location is on point. The staff was wonderful. The bar is my favorite one so far. "
The price is $127
$149 total
includes taxes & fees
May 27 - May 28
Aloft Louisville Downtown
Hawthorn Suites by Wyndham Louisville East
Lobby
Hawthorn Suites by Wyndham Louisville East
3.0 star property
8.8 out of 10, Excellent, (1001)
"It was a very nice hotel at a good price. The rooms were very quiet and nicely appointed. There were many food options nearby. I highly recommend it."
The price is $119
$140 total
includes taxes & fees
May 5 - May 6
Hawthorn Suites by Wyndham Louisville East
Residence Inn by Marriott Louisville Downtown
Fridge, microwave, stovetop, dishwasher
Residence Inn by Marriott Louisville Downtown
3.0 star property
8.8 out of 10, Excellent, (963)
"Great stay…perfect location and very nice room!"
The price is $109
$128 total
includes taxes & fees
May 27 - May 28
Residence Inn by Marriott Louisville Downtown
Springhill Suites By Marriott Louisville Hurstbourne North
Exterior
Springhill Suites By Marriott Louisville Hurstbourne North
3.0 star property
8.8 out of 10, Excellent, (1000)
"Nice place for the money! Would stay again!"
The price is $92
$108 total
includes taxes & fees
May 24 - May 25
Springhill Suites By Marriott Louisville Hurstbourne North
SpringHill Suites by Marriott Louisville Downtown
Exterior
SpringHill Suites by Marriott Louisville Downtown
3.0 star property
8.6 out of 10, Excellent, (1001)
"We got a suite with two queen beds and a pull out couch. It was so perfect for our girls’ trip. Loved having a refrigerator & microwave in the room too! The morning breakfast was also very good with lots of options! "
The price is $127
$149 total
includes taxes & fees
May 27 - May 28
SpringHill Suites by Marriott Louisville Downtown
Wingate by Wyndham Louisville East
Lobby
Wingate by Wyndham Louisville East
2.5 star property
8.6 out of 10, Excellent, (1001)
"Hotel was convenient, Close to stuff."
The price is $76
$89 total
includes taxes & fees
May 12 - May 13
Wingate by Wyndham Louisville East
Courtyard by Marriott Louisville Downtown
Exterior
Courtyard by Marriott Louisville Downtown
3.0 star property
8.6 out of 10, Excellent, (864)
"We really like this hotel. It has an attached parking lot with reasonable fees, is close walking distance to the yum center, Kentucky center for the arts, science museum, great restaurants, and bourbon experiences. The bistro has good food and drinks and the staff is always friendly. "
The price is $118
$139 total
includes taxes & fees
May 27 - May 28
Courtyard by Marriott Louisville Downtown
Don't see what you're looking for?
See all available properties in Cherokee Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Cherokee Seneca

Hotels in top Louisville neighborhoods Learn more about Cherokee Seneca
Louisville showing signage and street scenes as well as a small group of people

Downtown Louisville

3 out of top 10 points of interest in this area
4/5(1,812 area reviews)

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

Find hotels in Downtown Louisville

Cherokee Seneca Travel Info

Number of reviews
17,016
Location
Louisville, United States of America
Similar neighborhoods
Downtown Louisville, West Main Historic District and Fairgrounds
Accommodation
1,854 hotels
Known landmarks
Louisville Zoo, Louisville Mega Cavern and Colonel Sanders Museum
Hotels with entertainment
Budgetel Inn & Suites, Lux Townhouse Walk to All and ArTisTs CoTTaGe - A Place to Play!
Known for
History and walking
Lowest price
$76
Highest price
$224

Frequently asked questions

What is Cherokee Seneca like?

You'll be sure to have fun visiting Louisville's Cherokee Seneca neighborhood. Are you looking for Cherokee Seneca travel tips? Be sure to check out Cherokee Park and Seneca Park while you're in the neighborhood.

What's a favorite hotel to stay in Cherokee Seneca?

For your stay in Cherokee Seneca, Parklike Historic Estate in the Heart of Louisville w/Pool and Gardens is one of the top choices based on our traveler data.

If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to review top deals in Cherokee Seneca.

Where can I learn more about changing or cancelling my trip to Cherokee Seneca?

To find more details about changing or cancelling your trip to Cherokee Seneca, head over to our customer service page.

What is there to do around this Louisville neighborhood?

Spend some time exploring the natural setting of Cherokee Seneca with a visit to Cherokee Park and Seneca Park. While you're out sightseeing in Louisville, be sure to visit other sights like The Bard's Town or Peterson-Dumesnil House.

Recent reviews of Cherokee Seneca hotels

Hotel Genevieve

Hotel Genevieve

5/5 Excellent
"Great access to Whiskey Row and several unique restaurants right next door"
A verified traveler stayed at Hotel Genevieve
Posted 9 hours ago
Hotel Genevieve