Photo by Michele Butts

Find hotels in La Mesa, CA from $81

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 7,764 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

More cheap stays in La Mesa

Stay near popular La Mesa attractions

La Mesa Travel Info

Number of reviews
7,316
Accommodation
7,764 hotels
Highest price
$343
Lowest price
$81
Reasons to visit
San Diego Zoo, San Diego Air and Space Museum and San Diego Natural History Museum
Hotels with entertainment
126
5-star hotels
2
Hotels with family-friendly amenities
51

Frequently asked questions

What's the best place for a stay in La Mesa?

Best Western Plus La Mesa San Diego is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Motel 6 La Mesa, CA and Motel 6 La Mesa, CA - San Diego as top choices for your visit. See all available top hotels, or vacation rentals in La Mesa.

What's the top vacation rental in La Mesa?

Newly renovated waterfront stay with sweeping views, and a private washer/dryer: You might like this vacation home rental near La Mesa. It is near the beach and offers laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

Where can I learn more about changing or cancelling my trip to La Mesa?

To find more details about changing or cancelling your trip to La Mesa, head over to our customer service page.

What's the best place to stay on a budget in La Mesa?

Based on our traveler reviews, Motel 6 La Mesa, CA - San Diego is a top choice for a less expensive stay. View all budget hotels in La Mesa.

What's the best place to stay for a family vacation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a hotel with an outdoor pool and laundry facilities, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.

What's the best place to stay for a romantic getaway to La Mesa?

Heritage Inn La Mesa is a favorite hotel for couples, and features flat-screen TVs and free parking. Another choice for your romantic getaway is Motel 6 La Mesa, CA. See all romantic hotels in La Mesa.

What is the top LGBTQ-friendly hotel in La Mesa?

Heritage Inn La Mesa is a top LGBTQ-friendly hotel that features free parking and a sauna. Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.

What's the best pet-friendly accommodation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel for people traveling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet's trip include Motel 6 La Mesa, CA and Motel 6 La Mesa, CA - San Diego. See more pet-friendly hotel accommodations in La Mesa.

Where is the best hotel to stay close to Computer Museum of America?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free WiFi. It's located just a short 1 mi (1.6 km) from Computer Museum of America. Other good choices close by include Motel 6 San Diego - La Mesa and Days Inn & Suites by Wyndham San Diego SDSU.

What's the best hotel for a beach vacation in La Mesa?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is a top hotel for a beach vacation, and features free breakfast and free WiFi. Other good choices for your stay near the beach include Days Inn & Suites by Wyndham San Diego SDSU and Heritage Inn La Mesa. Head to Coronado Beach or Mission Bay for some quality time by the water.

What are some accommodations with pools in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel with a pool, free WiFi, and in-room flat-screen TVs. View all hotels with pools in La Mesa.

Recent reviews of La Mesa hotels
Expedia verified reviews