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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Hotel in Cape Girardeau with a full-service spa and free breakfast

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
1 bedroom, premium bedding, down comforters, pillowtop beds
Indoor pool, open 8 AM to 11 PM, sun loungers
Exterior
Free breakfast

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Laundry
  • Housekeeping

Room options

Available filters for rooms
Showing 9 of 9 rooms

View all photos for Suite, 1 King Bed

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed

9.6 out of 10
Exceptional
(29 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 Queen Bed

1 bedroom, premium bedding, down comforters, pillowtop beds

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillowtop bed
Separate bedroom
  • 400 sq ft
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds, Accessible (Mobility)

9.6 out of 10
Exceptional
(12 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(49 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room

1 bedroom, premium bedding, down comforters, pillowtop beds

Standard Room

8.4 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • 400 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | 1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Mobility)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Separate bedroom
Sofa bed
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillowtop bed
Separate bedroom
  • Sleeps 2
  • 1 Queen Bed

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About the neighborhood

Map
3253 William Street, Cape Girardeau, MO, 63701

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.4 miles
  • Cape Splash Family Aquatic Center - 5 min drive - 2.4 miles
  • Southeast Missouri State University - 6 min drive - 3.5 miles
  • Riverfront Bridge Park - 7 min drive - 4.0 miles
  • Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬6 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Panera Bread - ‬2 min walk
  • ‪Texas Roadhouse - ‬5 min walk
  • ‪O'Charley's Restaurant + Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel near Shawnee National Forest
You can look forward to free breakfast, dry cleaning/laundry services, and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the onsite spa. In addition to a business center, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
  • Swimming pool with sun loungers
  • Free self parking
  • An indoor pool, a vending machine, and free newspapers
  • Laundry services, a porter/bellhop, and smoke-free premises
  • Guest reviews speak highly of the breakfast and helpful staff
Room features
All 102 rooms feature comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property.
More amenities include:
  • Pillowtop mattresses and down comforters
  • Bathrooms with free toiletries and hair dryers
  • 52-inch flat-screen TVs with premium channels
  • Separate sitting areas, mini fridges, and microwaves

Languages

English

Similar properties

Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

  • Pool
  • Hot Tub
  • Breakfast included
  • Pet friendly
9.6 out of 10, Exceptional, 1,007 reviews
$90 nightly
The price is $102
Jul 20 - Jul 21
Total includes taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • Business center
  • Conference space
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–11 PM.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Jul 13, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Aug 1, 2025 start from $91.2, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?

No, pets are not allowed at this property.

How much is parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Self parking is free at this property.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?

Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 mi (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 787 out of 1003 reviews
Rating 8 - Good. 152 out of 1003 reviews
Rating 6 - Okay. 34 out of 1003 reviews
Rating 4 - Poor. 13 out of 1003 reviews
Rating 2 - Terrible. 17 out of 1003 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay.
Stayed 1 night in Jun 2025

10/10 Excellent

Josephine

Liked: Cleanliness, property conditions & facilities
This was our 2nd time staying at this hotel while traveling. Hotel is very well maintained, easy access off interstate and has a number of restaurants and gas stations for your convenience.
Stayed 1 night in Jun 2025

10/10 Excellent

Pam

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great room with everything i needed!!!
Stayed 1 night in Jul 2025

10/10 Excellent

Lucas

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent experience for our family. Every member of the staff we encountered were great. Breakfast was good, room was clean and spacious. Above and beyond expectations, would absolutely stay here again!
Stayed 2 nights in Jun 2025

10/10 Excellent

Frank

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff is phenomenal, and the room was very clean, accommodating all my needs.
Stayed 1 night in May 2025

10/10 Excellent

Constance

Liked: Cleanliness, staff & service, property conditions & facilities
Will definitely stay there again!!
Stayed 1 night in Apr 2025

10/10 Excellent

JUAN

Liked: Amenities
Cleanliness and staff really helpful
Stayed 1 night in May 2025

10/10 Excellent

sylvian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property is situated in a great spot! Lots to choose from for dining.
Stayed 2 nights in May 2025

10/10 Excellent

Nick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was super helpful at check in and very courteous throughout the whole stay
Stayed 2 nights in Apr 2025

10/10 Excellent

Taylor

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean hotel. The beds were not hard as brick very comfortable.
Stayed 1 night in May 2025

10/10 Excellent

Tammy

Liked: Staff & service, property conditions & facilities
We enjoyed our stay and would recommend
Stayed 1 night in Mar 2025

8/10 Good

Jacob

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to food and shopping not that far from SEMO
Stayed 2 nights in May 2025

8/10 Good

Terry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice rooms. Loved the jacuzzi. Bed wasn't the most comfortable, but not a bad night's sleep. I'd stay again.
Stayed 1 night in May 2025

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our stay both times on our vacation to New Orleans.
Stayed 1 night in Mar 2025

8/10 Good

Rebecca

Liked: Amenities
The beds were comfortable and the room was clean. The breakfast was cold and not very good.
Stayed 1 night in May 2025

10/10 Excellent

Joan

Liked: Cleanliness, amenities
Excellent Hotel. Good breakfast. Great room. We will stay again if we are in the area
Stayed 1 night in Mar 2025

10/10 Excellent

ken

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy walking distance to dining areas
Stayed 1 night in Mar 2025

4/10 Poor

Pat

Liked: Cleanliness, amenities, property conditions & facilities
Very noisy from the interstate and other people in the building
Stayed 1 night in May 2025

10/10 Excellent

Leonard

Great place to stay

Great stay.
Stayed 1 night in Nov 2024

10/10 Excellent

Heather

Liked: Cleanliness, amenities, property conditions & facilities
.
Stayed 2 nights in Jun 2025

6/10 Okay

Scott

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Personnel where polite and courteous
Stayed 1 night in Apr 2025

10/10 Excellent

Robin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was clan and the staff was friendly. The workout room and the pool were small but clean. The staff were friendly.
Stayed 3 nights in Mar 2025

10/10 Excellent

Ted

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
it was very clean, comfortable, Rooma are super cool for the price. Just a great experience.
Stayed 2 nights in Mar 2025

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lisa who was working in the breakfast area was very nice and helpful. Our room was very clean and comfortable.
Stayed 1 night in Mar 2025

10/10 Excellent

Nichole

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
So much around the hotel
Stayed 2 nights in Feb 2025