Title: The Best 4 Star Hotels in Appignano from $59 | Expedia.com [Appignano Travel Guide](https://expedia.com/Appignano.dx6341923)[Hotels in Appignano](https://expedia.com/Appignano-Hotels.d6341923.Travel-Guide-Hotels)[Vacation Rentals in Appignano](https://expedia.com/Appignano-Vacation-Rentals.d6341923.Travel-Guide-VacationRentals)[Flights to Appignano](https://expedia.com/Cheap-Flights-To-Appignano.d6341923.Travel-Guide-Flights)[Things to do in Appignano](https://expedia.com/Things-To-Do-In-Appignano.d6341923.Travel-Guide-Activities)[Car Rentals in Appignano](https://expedia.com/Car-Rentals-In-Appignano.d6341923.Car-Rental-Guide)[Appignano Vacation Packages](https://expedia.com/Appignano.d6341923.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Appignano 4 Star Hotels Tonight [Feb 10 - Feb 11](https://www.expedia.com/Hotel-Search?regionId=6341923&startDate=2026-02-10&endDate=2026-02-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 11 - Feb 12](https://www.expedia.com/Hotel-Search?regionId=6341923&startDate=2026-02-11&endDate=2026-02-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6341923&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6341923&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Appignano 4-star hotels ![Exterior](https://images.trvl-media.com/lodging/114000000/113130000/113123900/113123823/w996h662x2y3-0fe424dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room | Minibar, in-room safe, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/114000000/113130000/113123900/113123823/24cc7970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, massages](https://images.trvl-media.com/lodging/114000000/113130000/113123900/113123823/93bf3789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room | Minibar, in-room safe, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/114000000/113130000/113123900/113123823/7b8d0199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relais La Colombaia [](https://www.expedia.com/Appignano-Hotels-Relais-La-Colombaia.h113123823.Hotel-Information) Appignano 10/10 Exceptional (5 reviews) "La struttura è nuova super curata, le camere nuove e ben arredate e lo staff molto attento. " ![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg) Alessandro $120 nightly $132 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Appignano-Hotels-Relais-La-Colombaia.h113123823.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9680000/9674000/9673997/e6756910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9680000/9674000/9673997/f2bc10d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9680000/9674000/9673997/4af5b09e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Regional cuisine](https://images.trvl-media.com/lodging/10000000/9680000/9674000/9673997/ad53e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Osteria dei Segreti [](https://www.expedia.com/Appignano-Hotels-Osteria-Dei-Segreti.h9673997.Hotel-Information) Appignano 9.8/10 Exceptional (47 reviews) "Great place. Pet friendly " ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Andreas $169 nightly $186 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Appignano-Hotels-Osteria-Dei-Segreti.h9673997.Hotel-Information) ![Fountain](https://images.trvl-media.com/lodging/31000000/30990000/30989700/30989676/ba2dd6db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/31000000/30990000/30989700/30989676/ed34159b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/31000000/30990000/30989700/30989676/c2a9203e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/31000000/30990000/30989700/30989676/4d59d959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Villa Verdefiore [](https://www.expedia.com/Appignano-Hotels-Hotel-Villa-Verdefiore.h30989676.Hotel-Information) Appignano 10/10 Exceptional (8 reviews) "This hotel is so lovely. It was quiet. Set back from the road, it’s hard to see at first how gorgeous the hotel entrance is. The gardens are beautifully tended and you’ll not hear much more than bird song and the occasional yip from a fox. This is rural Italy at its best. We were charmed by the friendly staff - Stefano was exceptionally helpful. The dining experience was true to Le Marche. Our room was beyond comfortable, with thoughtful items like bedroom slippers and all sorts of toiletries.... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Terrence [](https://www.expedia.com/Appignano-Hotels-Hotel-Villa-Verdefiore.h30989676.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Appignano-Hotels.s40-0-d6341923.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Appignano-Hotels.s40-0-d6341923.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Appignano. ![View Place & Spa](https://images.trvl-media.com/lodging/97000000/96730000/96721900/96721832/b6c037c7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### View Place & Spa Via Flaminia 109 Numana AN $130 nightly $143 total Feb 11 - Feb 12 Total with taxes and fees 9.6/10 Exceptional! (39 reviews) [](https://expedia.com/Numana-Hotels-Vista-Place-Numana.h96721832.Hotel-Information) Still don't see what you're looking for? [See all properties in Appignano.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40&star=40&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F11%2F2026&endDate=2%2F12%2F2026®ionId=6341923&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Appignano Hotel Reviews ![San Francesco Hotel](https://images.trvl-media.com/lodging/3000000/2540000/2538800/2538750/89de6e06_y.jpg) ### San Francesco Hotel 10/10 Excellent "Everything was so clean, in perfect order, a very handsome building! The staff, those at reception as well as those in the dining room, were all so professional and courteous! What a pleasure to have stayed there! I highly recommend this hotel to everyone! " [](https://expedia.com/Loreto-Hotels-San-Francesco-Hotel.h2538750.Hotel-Information) ![Grand Hotel Palace](https://images.trvl-media.com/lodging/1000000/50000/45800/45710/9d236407_y.jpg) ### Grand Hotel Palace 10/10 Excellent "Beautiful hotel, modern and charming. Great location, very comfortable bed, and impressive rooms. Excellent restaurant and fantastic sta" [](https://expedia.com/Ancona-Hotels-Grand-Hotel-Palace.h45710.Hotel-Information) ![EGO Hotel](https://images.trvl-media.com/lodging/9000000/8350000/8340300/8340253/0e9d626f_y.jpg) ### EGO Hotel 10/10 Excellent "Always excellent. Staff are wonderful and authentically kind and helpful. Spa perfection in stress management! Area steeped in history. We love it here and have been returning for years. Highly recommended. " [](https://expedia.com/Ancona-Hotels-EGO-Hotel.h8340253.Hotel-Information) ![Hotel Horizon](https://images.trvl-media.com/lodging/4000000/3580000/3576800/3576748/856e29d9_y.jpg) ### Hotel Horizon 10/10 Excellent "Clean hotel " [](https://expedia.com/Montegranaro-Hotels-Hotel-Horizon.h3576748.Hotel-Information) ![SeePort Hotel](https://images.trvl-media.com/lodging/10000000/9680000/9677800/9677716/f10bcd39_y.jpg) ### SeePort Hotel 10/10 Excellent "Perfect location and great views of the ocean " [](https://expedia.com/Ancona-Hotels-SeePort-Hotel.h9677716.Hotel-Information) ![Hotel Miramare](https://images.trvl-media.com/lodging/6000000/5210000/5208900/5208868/25170b98_y.jpg) ### Hotel Miramare 10/10 Excellent "Fantastic stay in a wonderful location. We will definitrly be back! " [](https://expedia.com/Civitanova-Marche-Hotels-Hotel-Miramare.h5208868.Hotel-Information) ![Hotel Federico II](https://images.trvl-media.com/lodging/3000000/2440000/2430400/2430392/96a2b74f_y.jpg) ### Hotel Federico II 10/10 Excellent "Was nice " [](https://expedia.com/Jesi-Hotels-Hotel-Federico-II.h2430392.Hotel-Information) ![G Hotel](https://images.trvl-media.com/lodging/3000000/2800000/2794400/2794335/87f7fb28_y.jpg) ### G Hotel 10/10 Excellent "Great stay, breakfast ok. " [](https://expedia.com/Osimo-Hotels-G-Hotel.h2794335.Hotel-Information) ![NH Ancona](https://images.trvl-media.com/lodging/1000000/30000/23600/23577/w3840h2562x0y0-4e92e59f_y.jpg) ### NH Ancona 10/10 Excellent "This is an excellent hotel, with terrific staff, comfortable rooms and a very good breakfast. " [](https://expedia.com/Ancona-Hotels-NH-Ancona.h23577.Hotel-Information) ## Find out more about Appignano ## Appignano Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Appignano, Marche are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Appignano 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Appignano. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Appignano, Marche, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Appignano hotels offer everything your heart desires. ## Explore a world of travel with Expedia - More ways to book - [Book 4 Star Hotels in Appignano on Expedia.it ](https://www.expedia.it/4Stelle-Appignano-Hotel.s40-0-d6341923.Guida-Viaggi-Filtro-Hotel)