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Featured Florida Keys 4 Star Hotels

See all 848 Hotels in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (3,459 reviews)
So Clean and Great LocationDon't have to leave to get beach access, ocean pier access and pool access. Food at cafe was great. Live music and bars where you need them. Very clean and friendly. Would stay here again. Just a short walk to Duval to every store, restaurant, anything you need.
Jun 14, 2018

Southernmost Beach Resort$229

Southernmost Beach Resort$229
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (567 reviews)
Beautiful HotelThe hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent. The location of the building that we stayed in was poor and far away from everything, try and avoid Building 4 if you can, access to everything from here is not thought through. The hotel reception ...
Jun 13, 2018

Oceans Edge Key West Resort, Hotel & Marina$134

Oceans Edge Key West Resort, Hotel & Marina$134
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (305 reviews)
Exceptional but expensiveIts a great location. The staff are helpful. Rooms with a seaview are much better than the pool view rooms. Restaurant and bar at sunset are delightful. Free water bottles and in room coffee are great. Its a nice hotel but overpriced with parking fees and resort fees added on.
Jun 12, 2018

Margaritaville Key West Resort & Marina$250

Margaritaville Key West Resort & Marina$250
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.6 out of 5 (213 reviews)
Better than expectedOff the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel with great views of the marina. Very comfortable room. Staff friendly and accommodating. Restaraunt on site had an excellent Mahi sandwich. Definitely worth at least one meal while here. Would stay here ...
Jun 15, 2018

The Perry Hotel Key West$153

The Perry Hotel Key West$153
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (1,234 reviews)
Fair. O.K.Rust running down the shower towel rack can be easily fixed, but is not. Room not as clean as it should be. 3 great hotel staff members at desk. Young man not helpful. Pool area good and outside bar very nice. 1/2 price drinks appreciated (made real price reasonable). Just charge 1/2 prince to drink ...
Jun 4, 2018

24 North Hotel Key West$152

24 North Hotel Key West$152
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (1,250 reviews)
Very niceExcelent location. The employees were very nice, helpful. The room was clean,nicely decorated
May 29, 2018

The Gates Hotel Key West$144

The Gates Hotel Key West$144
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
    4.0 out of 5.0
     
     
    4.4 out of 5 (1,552 reviews)
    Wonderful hotel with a beachGreat hotel with a beautiful beach and great amenities. Would definitely return to this resort and recommend it to friends
    Jun 11, 2018

    Pier House Resort & Spa$289

    Pier House Resort & Spa$289
    Casa Marina, A Waldorf Astoria Resort

    Casa Marina, A Waldorf Astoria Resort

    1500 Reynolds Street, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.2 out of 5 (2,195 reviews)
    Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
    May 7, 2018

    Casa Marina, A Waldorf Astoria Resort$269

    Casa Marina, A Waldorf Astoria Resort$269
    The Marker Waterfront Resort Key West

    The Marker Waterfront Resort Key West

    200 William Street, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.5 out of 5 (976 reviews)
    Best Hotel in Key WestThis is by far the best hotel in Key West. We arrived at 10AM and were immediately checked into our room, which is very tastefully decorated in an island theme. The 3 pools are amazing, as well as the frozen drinks and live music (during the day so no one loses sleep). The location was phenomenal ...
    Jun 15, 2018

    The Marker Waterfront Resort Key West$169

    The Marker Waterfront Resort Key West$169
    Tranquility Bay Beachfront Hotel and Resort

    Tranquility Bay Beachfront Hotel and Resort

    2600 Overseas Hwy, Marathon
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.5 out of 5 (1,127 reviews)
    Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
    May 3, 2018

    Tranquility Bay Beachfront Hotel and Resort$149

    Tranquility Bay Beachfront Hotel and Resort$149
    Map

    You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

    Properties as Gorgeous as Florida Keys

    Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

    Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

    Book a 4-Star Hotel in Florida Keys Today!

    A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

    Recently booked 4 Star Hotels in Florida Keys

    Parmer's Resort
    2.5 out of 5.0
    Last booking: 1 minute ago
    Sands of Islamorada
    2.5 out of 5.0
    Last booking: 8 minutes ago
    The Reach, A Waldorf Astoria Resort
    4.0 out of 5.0
    Last booking: 14 minutes ago
    Hyatt Place Marathon Florida Keys
    3.0 out of 5.0
    Last booking: 27 minutes ago
    Tranquility Bay Beachfront Hotel and Resort
    4.0 out of 5.0
    Last booking: 28 minutes ago
    Fairfield Inn and Suites by Marriott Key West
    3.5 out of 5.0
    Last booking: 32 minutes ago
    Fairfield Inn & Suites by Marriott Key West, Keys Collection
    3.0 out of 5.0
    Last booking: 32 minutes ago
    Chesapeake Beach Resort
    2.5 out of 5.0
    Last booking: 1 hour ago
    Skipjack Resort & Marina
    3.0 out of 5.0
    Last booking: 1 hour ago