Find 5 Star Hotels in Florence, MS from $133

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florence.
The Westin Jackson

The Westin Jackson

407 South Congress Street Jackson MS
$152 nightly
The price is $170 total per night from Jan 1 to Jan 2
$170 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
9/10 Wonderful! (835 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Find out more about Florence

Ready for an incredible adventure? Add further enjoyment on your next trip to Florence by treating yourself to the best of the best when it comes to accommodation. It's an ideal pairing. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Florence so popular in the last year. There's no reason to delay a getaway to Florence any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Florence and get ready to enjoy the getaway of a lifetime. Don't wait any longer!

Get a Great Deal on 5-Star Hotels in Florence

You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all ready for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A concierge to help you make reservations at that outstanding restaurant? A rejuvenating facial treatment to help your cares fall away? Plush carpeting, delectable chocolate desserts, and even spectacular views...these hotels are one-of-a-kind. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Florence are the perfect place to rest up after a busy day.

Your Getaway Starts Today

The results are in, and Florence 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Your great getaway is just a mouse-click away. Choose one of Expedia's Florence 5-star hotels today and decompress in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florence?
How much you pay for a 5-star hotel in Florence depends on factors such as when you want to go and the length of your escape. An insider tip for scoring the best deal? Use our pricing filters to check out the available options for your chosen dates.

  • Search for the lowest price per night from $133

What makes a hotel 5 stars in Florence?
From high-end restaurants and 24-hour fitness centers to swimming pools and dreamy bedding, the 5-star experience in Florence is all about indulgence and comfort. But it requires more than just upscale perks to get a 5-star rating. Stays also have to deliver remarkable guest-centric services like beauty treatments, on-site dry cleaning and laundry and concierge services.
Are there any 5-star all-inclusive resorts in Florence?
Use Expedia's filter tool to find an upscale getaway in Florence where most of what you need is included. Next, narrow your results for accommodations that have a rating of 5 stars and are deemed "All inclusive." The most important thing on the to-do list at these stays? Pure enjoyment and indulgence.

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