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Find 5 Star Hotels in Midtown, FL from $145
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Our top choices for Midtown 5-star hotels
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
Mary Anne
$401 nightly
The price is $448
Jan 12 - Jan 13, 2026
Total with taxes and fees
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Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Midtown.
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$254 nightly
The price is $284 total per night from Dec 21 to Dec 22
$284 total
Dec 21 - Dec 22
Total with taxes and fees
8.8/10 Excellent! (1,697 reviews)
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Top Midtown Hotel Reviews
Sundial Beach Resort & Spa
10/10 Excellent