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A castle on a hill with dense forest.

Find 5 Star Hotels in Spoleto from $122

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Check prices for these dates, December 13 – 14, 2026

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Our top choices for Spoleto 5-star hotels

1. Nun Assisi Relais Spa Museum

A stone-walled indoor pool area with a person in a robe.

2. Posta Donini 1579 UNA Esperienze

A swimming pool with a person swimming, a wooden deck with lounge chairs, and a flower arrangement.

3. Borgobrufa Spa Resort Adults Only

A pool with lounge chairs and umbrellas, surrounded by stone walls and a view of the countryside.

4. Borgo Tre Vaselle

A dining area with a long wooden table set for breakfast, surrounded by stone walls and large windows.

5. Ascesi Resort

An interior with stone arches, a central courtyard, and a potted plant.

6. San Gemini Palace

A table set with breakfast items on a balcony overlooking a scenic view.

7. Agriturismo Agrileisuretime

A swimming pool with clear water, surrounded by lounge chairs and thatched umbrellas, set against a backdrop of mountains and a sunset.

Top Spoleto Hotel Reviews

San Gemini Palace

A table set with breakfast items on a balcony overlooking a scenic view.

Nun Assisi Relais Spa Museum

A stone-walled indoor pool area with a person in a robe.

Ascesi Resort

An interior with stone arches, a central courtyard, and a potted plant.

Borgo Tre Vaselle

A dining area with a long wooden table set for breakfast, surrounded by stone walls and large windows.

Posta Donini 1579 UNA Esperienze

A swimming pool with a person swimming, a wooden deck with lounge chairs, and a flower arrangement.

Podere Le Marene

A glass table with chairs and vases, set outdoors with a lake and trees in the background.

Find out more about Spoleto

Why not request complete opulence on your excursion to Spoleto? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Spoleto so popular in the last year. There's no reason to delay a getaway to Spoleto any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in Spoleto are the perfect places to relax in during your next escape. You deserve the great vacation you're dreaming about.

Book the Best Spoleto 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Top-notch customer care, granite-tiled bathrooms, and fabulous spa offerings are all on offer. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A Swedish massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Plush carpeting, delectable chocolate desserts, and even spectacular views...these hotels have it all.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Spoleto are the perfect place to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Spoleto 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Choose one of the 5-star hotels in Spoleto today and decompress in the lap of luxury tomorrow.

Frequently Asked Questions

How much does it cost to stay in a 5-star hotel in Spoleto?

You can find a range of pricing options for a 5-star hotel in Spoleto on Expedia. How much you'll pay will depend on when you want to travel, length of your trip and other factors. Compare available accommodations for your preferred dates and make use of our pricing and other filters to find the ideal luxury stay.

What makes a hotel 5 stars in Spoleto?

From gourmet restaurants and all-day fitness centers to swimming pools and luxury bedding, the 5-star experience in Spoleto is all about luxury and relaxation. But it requires more than just top-notch conveniences to earn a 5-star rating. Stays must also deliver superb guest-centric services like in-room massage treatments, dry cleaning and laundry and 24-hour room service.

Are there any 5-star all-inclusive resorts in Spoleto?

Expedia's filter tool is the best way to search for exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to show the finest resorts in Spoleto where your lodging, meals, entertainment and activities are included in the price. At these getaways, your trip is pure relaxation and indulgence from the moment you arrive.

Are there any 5-star vacation rentals in Spoleto?

Our site doesn't offer any 5-star vacation rentals in Spoleto. However, you can still find a range of top-rated options where the only thing on your agenda will be to kick back and have fun. View what's available by checking out our vacation rentals in Spoleto.

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