Astrodome Vacations from $239

Book a Hotel + Flight or Car together to unlock savings

Photo by George Zimzores

Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Moody Gardens Hotel, Spa and Convention Center
 Palace Inn Blue Edgebrook
Hotel Granduca Houston
Hilton Houston North

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $170 total per night from Nov 13 to Nov 14
$170 total
Nov 13 - Nov 14
Total with taxes and fees
9/10 Wonderful! (3,549 reviews)
"Staff and facilities were amazing!"

Reviewed on Oct 10, 2025

Blossom Hotel Houston
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from Oct 15 to Oct 16
$163 total
Oct 15 - Oct 16
Total with taxes and fees
9/10 Wonderful! (2,020 reviews)
"The door hanging card should include a message to have room cleaned without the need to inform the front desk of this request."

Reviewed on Oct 8, 2025

Hyatt Place Houston Medical Center
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd, Houston, TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $150 total per night from Oct 19 to Oct 20
$150 total
Oct 19 - Oct 20
Total with taxes and fees
9.2/10 Wonderful! (977 reviews)
"It was an extremely good experience. The staff was helpful and friendly, and the shuttle service was greatly appreciated."

Reviewed on Oct 11, 2025

Hilton Garden Inn Houston Medical Center, TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.