Astrodome Vacations from $175

Book a Hotel + Flight or Car together to unlock savings

Photo by Hugo Martinez Mier

Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Red Lion Inn & Suites Katy
Margaritaville Lake Resort, Lake Conroe/Houston
Captain Suites
Hotel Saint Augustine
Moody Gardens Hotel, Spa and Convention Center

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $146 total per night from Nov 28 to Nov 29
$146 total
Nov 28 - Nov 29
Total with taxes and fees
9/10 Wonderful! (3,584 reviews)
10/10

Reviewed on Oct 28, 2025

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Oct 30 to Oct 31
$139 total
Oct 30 - Oct 31
Total with taxes and fees
9/10 Wonderful! (2,071 reviews)
The breakfast was top notch! The only complaint I had was when I was done didn’t know if I was supposed to leave the dirty dishes or put them somewhere! The staff was really friendly! Thank you Adam

Reviewed on Oct 27, 2025

Hyatt Place Houston Medical Center
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET, Houston, TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Nov 23 to Nov 24
$139 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (1,144 reviews)
Room was comfortable and staff was great

Reviewed on Oct 27, 2025

Hyatt House Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.