Astrodome Vacations from $416

Book a Hotel + Flight or Car together to unlock savings

Photo by Danielle Bragg

Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Home Place Inn
Holiday Inn Houston Downtown by IHG
Clarion Pointe Galveston - Beachfront
Experience a First Class Stay - 2 BDRM

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from May 10 to May 11
$160 total
May 10 - May 11
Total with taxes and fees
9/10 Wonderful! (3,776 reviews)
As a family pack with two kids, I used to love staying at Blossom anytime we visited Houston, but this was our last stay. There were several people pulling up in “hot boxed” vehicles (which to each their own but not family friendly), but the catalyst was coming downstairs at around 9pm to find a ...

Reviewed on Apr 9, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $149 total per night from Apr 19 to Apr 20
$149 total
Apr 19 - Apr 20
Total with taxes and fees
9.2/10 Wonderful! (2,440 reviews)
Second time staying at this hotel. I chose it for the convenience of location.

Reviewed on Apr 8, 2026

Hyatt Place Houston Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $147 total per night from May 9 to May 10
$147 total
May 9 - May 10
Total with taxes and fees
8.4/10 Very Good! (3,741 reviews)
Clean room

Reviewed on Apr 9, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.