Astrodome Vacations from $390

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Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Moody Gardens Hotel, Spa and Convention Center
Residence Inn by Marriott Houston Downtown/Convention Center
Great Wolf Lodge Webster
The Hayworth Apartments By Barsala
Hotel Saint Augustine

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Aug 3 to Aug 4
$161 total
Aug 3 - Aug 4
Total includes taxes and fees
9/10 Wonderful! (3,381 reviews)
"A very nice stay for our anniversary"

Reviewed on Jul 1, 2025

Blossom Hotel Houston
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Jul 12 to Jul 13
$152 total
Jul 12 - Jul 13
Total includes taxes and fees
9/10 Wonderful! (1,751 reviews)
"Be aware they will need a card to put a $50 hold at check in and parking is $15 each night"

Reviewed on Jun 30, 2025

Hyatt Place Houston Medical Center
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 out of 5
1301 Braeswood Blvd, Houston, TX
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $99 total per night from Jul 23 to Jul 24
$99 total
Jul 23 - Jul 24
Total includes taxes and fees
6/10 (1,012 reviews)
Our stay
"It was real convenient being so close to MD Anderson Hospital! Shower didn’t work and some kid pulled the fire alarm"

Reviewed on Jun 21, 2025

Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.