Astrodome Vacations from $223

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Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Place Houston-North
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston North
Reside Houston Dwntwn, Wyndham
Kompose Residences Houston Cy-Fair

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $181 total per night from Mar 29 to Mar 30
$181 total
Mar 29 - Mar 30
Total with taxes and fees
9/10 Wonderful! (3,736 reviews)
Polite stuff, clean room, nice view,

Reviewed on Feb 27, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Mar 29 to Mar 30
$158 total
Mar 29 - Mar 30
Total with taxes and fees
9.2/10 Wonderful! (2,386 reviews)
The room was clean and excellent, and the staff provided a great service!

Reviewed on Feb 27, 2026

Hyatt Place Houston Medical Center
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $169 total per night from Mar 29 to Mar 30
$169 total
Mar 29 - Mar 30
Total with taxes and fees
9.2/10 Wonderful! (1,254 reviews)
Clean and close

Reviewed on Feb 24, 2026

Hyatt House Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.