Astrodome Vacations from $166

Book a Hotel + Flight or Car together to unlock savings

Photo by Hugo Martinez Mier
  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Houston Southwest I-69
ECLIPZ Modern CEO Corp House
Margaritaville Lake Resort, Lake Conroe/Houston
Landing Houston Space Center
4Bdrm 2Bath 4Beds - Sugarland Richmond

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $154 total per night from Feb 8 to Feb 9
$154 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (3,656 reviews)
Everything was amazing at this hotel! Staff super friendly and helpful the place was very clean and the beds super comfy! Loved the location too

Reviewed on Jan 5, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Jan 16 to Jan 17
$138 total
Jan 16 - Jan 17
Total with taxes and fees
9/10 Wonderful! (2,230 reviews)
The room was very clean and comfortable, and the front desk staff were warm and attentive.

Reviewed on Jan 6, 2026

Hyatt Place Houston Medical Center
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $129 total per night from Feb 6 to Feb 7
$129 total
Feb 6 - Feb 7
Total with taxes and fees
9/10 Wonderful! (1,214 reviews)
Really enjoyed my stay at hyatt.

Reviewed on Jan 3, 2026

Hyatt House Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Astrodome

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.