Astrodome Vacations from $224

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Your Astrodome Vacation

Our Astrodome vacation packages are an easy and handy way to plan and book your next escape. Uncover the magic of this unique neighborhood without the stress of planning it all yourself. Your trip to Astrodome wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Expedia can put your travel plans into action. Book your perfect Astrodome vacation today.

The Latest Astrodome Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Place Houston/Galleria
Margaritaville Lake Resort, Lake Conroe/Houston
Hotel Granduca Houston
Heritage Place Houston Brookhollow
La Colombe d'Or Hotel

Where to stay in Astrodome

Find the best Astrodome areas and neighborhoods for the activities you enjoy most. Learn more about Astrodome

Astrodome Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $170 total per night from Jul 31 to Aug 1
$170 total
Jul 31 - Aug 1
Total with taxes and fees
9/10 Wonderful! (3,848 reviews)
"Booked a 2 room suite for an hefty price… specifically to have 2ROOMS.. and they gave my room to someone else. They made us take 2 rooms on separate floors but only after we had to use the room they gave us for a night which entailed sharing a bed.. totally not ok! And it ruined the vibe. Totally ..."

Reviewed on Jul 1, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $149 total per night from Jul 19 to Jul 20
$149 total
Jul 19 - Jul 20
Total with taxes and fees
9.2/10 Wonderful! (2,578 reviews)
"The issues we had; we were there from Thurs to Sunday and never saw cleaning staff. I even told staff to clean and they didn’t. Also, we called down for clean towels and they never came. Had to go down to get them ourselves. Also, there is no 24 hr shuttle as advertised. It’s only for the Medical ..."

Reviewed on Jun 30, 2026

Hyatt Place Houston Medical Center
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Jul 19 to Jul 20
$149 total
Jul 19 - Jul 20
Total with taxes and fees
9.2/10 Wonderful! (1,244 reviews)
"The air conditioning worked which was important in the Houston heat"

Reviewed on Jun 28, 2026

Hyatt House Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Astrodome attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.