Title: Barrio Sur Vacation Packages 2026 from $613 | Expedia.com

[Hotels in Barrio Sur](https://expedia.com/Barrio-Sur-Hotels.d829297886230487040.Travel-Guide-Hotels)[Flights to Colon](https://expedia.com/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights)[Things to do in Colon](https://expedia.com/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities)[Car Rentals in Barrio Sur](https://expedia.com/Car-Rentals-In-Barrio-Sur.d829297886230487040.Car-Rental-Guide)

![](https://images.trvl-media.com/place/829297886230487040/f369fa93-5766-4cf5-866c-bfa1cf04f904.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Barrio Sur Vacations from $613

## Book a Hotel + Flight or Car together to unlock savings

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## The Latest Barrio Sur Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Mahogany Suites

$613

per person

Apr 2 - Apr 6

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

10/10 Exceptional! (1 review)

Excellent apartment on a golf resort. 5 Star.

Reviewed on Jan 28, 2026

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,023

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Location, amenities and staff were great.

Reviewed on Feb 3, 2026

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

Save 100% on your flight

$762

per person

Mar 13 - Mar 20

found 20 hours ago

Roundtrip non-stop flight included

Miami (MIA) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Panama

Bella Vista

$762

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (4,515 reviews)

The hotel is centrally located n Panama City from where one can easily access to other part of the city by a short taxi ride, Our hotel room is always kept very clean, and it is very spacious and takes plenty of sunshine. Bathroom is a decent size with a .modern shover and double sinks it is always kept very clean and spotless with clean towels which are daily changed. No reason to say 24 hours receptions, the receptionists are multi lingual and fluent in English also very friendly, helpful and professional. Hotel provides excellent and very delicious breakfast with a great diversity of food including vegetarian and vegan choices, In addition, there are two restaurants: 1\. Spanish Restaurant; 2, Ibiza Restaurant near the swimming pool. Both restaurants provides excellent and delicious meals with a reasonable price. We really like The Spanish Restaurant very much because the quality of the meals and food in this restaurant are very authentic and as good as Spanish food in Spain even better in some instances. Swimming pool is great and I believe in an olympic size swimming pool. Weekends it becomes relatively crowded and also locals participate with larger number than that of other days. I believe that Hotel Riu Plaza in Panama City is an excellent place to spent your vacation.

Reviewed on Feb 5, 2026

![Riande Aeropuerto Hotel & Casino](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Riande Aeropuerto Hotel & Casino

$848

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.6/10 Excellent! (1,884 reviews)

everything was ok with the exception no hot water in the shower/had it in the sink but shower was without

Reviewed on Feb 3, 2026

## Where to stay in Barrio Sur

Find the best Barrio Sur areas and neighborhoods for the activities you enjoy most. [Learn more about Barrio Sur](https://expedia.com/Colon-Barrio-Sur.dx829297886230487040)

![#Panama #Canal 

Gatun locks
Por volta das 6 da manhã já tínhamos passado o quebra-mar que antecede as Gatun locks. Depois da passagem de alguns navios foi a nossa vez de sermos elevados 26 metros em 3 etapas até ao Gatun Lake. Atravessamos o lago, o Culebra Cut (Canal aberto nas rochas e em forma de cobra com 12,6 Km de comprimento), a Centenial Bridge e chegamos a Pedro Miguel Locks, que tem apenas uma câmera. Aqui descemos 9 metros para o Miraflores Lake. Lago pequeno e logo chegamos às Miraflores Locks. São compostas de 2 câmeras que nos descem até ao nível do Pacífico. Estes locks têm as gates mais altas devido às diferenças entre as marés do Pacífico. Atravessados estes locks chegamos ao Pacífico. Passamos ainda por baixo da ponte das Américas, que é parte da rodovia Pan-americana, que liga o sul da América do sul com o Alasca na América do norte. A travessia toda durou em torno de 9 horas. Durante a travessia os navios são auxiliados por pares de locomotivas. Dependendo do tamanho do navio, podem ser usadas até 8 locomotivas. A água que enche as câmeras, vem do Gatun Lake e são usados 197 milhões de litros de água para cada travessia. Por isso é de suma importância a conservação da floresta tropical em torno do lago. As dimensões máximas permitidas para os navios é 32,31 m de largura, 294,13 m de comprimento e 12,04 m de calado.

Gatun locks
By 6am we had already passed the breakwater that precedes the Gatun locks. After the passage of some ships it was our turn to be lifted 26 meters in 3 steps to Gatun Lake. We cross the lake, the Culebra Cut](https://images.trvl-media.com/place/6024083/8bf71600-226a-4a20-b277-bfebc4783659.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Cristobal

 Travelers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area. 

[Find hotel + flight trips in Cristobal](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Cristobal&DestID=6024083&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Gatun

 The museums and monuments are just a few features travelers like about Gatun. If you want to do some sightseeing nearby, Canal Expansion Observation Center and Gatun Locks are a few top places to visit. 

[Find hotel + flight trips in Gatun](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Gatun&DestID=6025905&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Coco Solo

 If you're spending some time in Coco Solo, Colon Free Zone and Limon Bay are top sights worth seeing. 

[Find hotel + flight trips in Coco Solo](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Coco%20Solo&DestID=553248635974899440&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Barcelona Christopher Columbus monument](https://images.trvl-media.com/place/829297880595460096/89637f4a-c300-40a8-906c-431bcafa7516.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Barrio Norte

1 out of top 10 points of interest in this area

 While visiting Barrio Norte, you might make a stop by sights like Limon Bay and Monument to Christopher Columbus. 

[Find hotel + flight trips in Barrio Norte](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Barrio%20Norte&DestID=829297880595460096&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Barrio Sur Hotel Deals

![Radisson Colon 2,000 Hotel & Casino](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Radisson Colon 2,000 Hotel & Casino

Paseo Gorgas, Calle 13 Colon Colon

Fully refundableReserve now, pay when you stay

$101 nightly

$111 total

Feb 21 - Feb 22

Total with taxes and fees

8/10 Very Good! (857 reviews)

Nice clean room and the staff was so friendly. Mr Javier was such a great guy.

Reviewed on Jan 23, 2026

[](https://expedia.com/Hotel-Search?startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&selected=2147349&PinnedHotelID=2147349&HadPinnedHotel=true&regionId=829297886230487040)

![Hotel Andros](https://images.trvl-media.com/lodging/12000000/11640000/11631800/11631712/f6ff0755_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Andros

Ave. Herrera, entre Calles 9 y 10 Colon Colon

7.8/10 Good! (159 reviews)

All great

Reviewed on Jan 31, 2026

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=11631712&PinnedHotelID=11631712&HadPinnedHotel=true&regionId=829297886230487040)

[](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=11631712&PinnedHotelID=11631712&HadPinnedHotel=true&regionId=829297886230487040)

![Hotel Sotelo](https://images.trvl-media.com/lodging/24000000/23360000/23358200/23358184/5961aa1e_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Sotelo

Calle 11, Ave. Amador Colon Panama

Fully refundableReserve now, pay when you stay

$32 nightly

$35 total

Feb 8 - Feb 9

Total with taxes and fees

7.6/10 Good! (38 reviews)

The hotel room was clean however the paint on the walls is dirty. The bedhead is discolored, bathroom mirror old and discolored. Air conditioner is very dirty. Bed is not comfortable. I ask front desk for ticker bedsheets buy there don't have. I booked for 6 days but leaves on the third day. The ...

Reviewed on Jul 11, 2024

[](https://expedia.com/Hotel-Search?startDate=2%2F8%2F2026&endDate=2%2F9%2F2026&selected=23358184&PinnedHotelID=23358184&HadPinnedHotel=true&regionId=829297886230487040)

[See all 46 properties in Barrio Sur](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026&regionId=829297886230487040)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Barrio Sur

#### Colon Free Zone

During your trip to Colon, you can search for that perfect souvenir at Colon Free Zone. 

[](https://expedia.com/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction)

#### Colon 2000

During your visit to Colon, you can search for that perfect souvenir at Colon 2000\. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants. 

[](https://expedia.com/Colon-2000-Barrio-Sur.d6286212.Vacation-Attraction)

### Things to do

![Panama Canal 3 Locks Ocean to Ocean Half Day Tour](https://mediaim.expedia.com/localexpert/50961322/65ccb688-e9d6-4040-ae82-ed9e93a509d8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama Canal Tour: New Locks Agua Clara & Gatun Atlantic Side

$47

per adult

[](https://expedia.com/things-to-do/panama-canal-tour-new-locks-agua-clara-gatun-atlantic-side.a50961322.activity-details)

![Panama Canal Train, Agua Clara Canal Lock Center & Colon Fort](https://mediaim.expedia.com/localexpert/1691850/cad3931e-9837-4255-a38e-5b634c7a9d04.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Agua Clara Canal Lock Center & Colon Fort

$225

per adult

[](https://expedia.com/things-to-do/agua-clara-canal-lock-center-colon-fort.a1691850.activity-details)

![First Ave. Cristo Redentor ](https://mediaim.expedia.com/localexpert/50090157/50d14893-4178-45d7-9135-6b3d604ec729.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Colon City tour: Exploring Caribbean roots, food, and culture

$105

per adult

[](https://expedia.com/things-to-do/colon-city-tour-exploring-caribbean-roots.a50090157.activity-details)

[See all activities in Colon](https://expedia.com/things-to-do/search?rid=829297886230487040)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.