Colon Vacations from $629

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Colon Vacation

With one of our vacation packages to Colon, you'll discover countless opportunities for fun and excitement. There's a lot to look forward to, including its lush beauty and laid-back lifestyle. If your trip to Colon includes a little sightseeing, don't miss much-loved attractions like Colon 2000, Monument to Christopher Columbus and Juventud Park. Your Colon vacation is clicks away. Explore hotels, airfares and more on Expedia for a trip that's tailored to suit your travel style.

The Latest Colon vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Finca Lerida
Central Hotel Bocas del Toro
Central Hotel Panama Casco Viejo
Hotel Panamonte
Villa Botero By Casa Mojito B&B
Don't see what you're looking for?
See all available trips from Columbus to Colon
View all trips

Where to stay in Colon

Find the best Colon areas and neighborhoods for the activities you enjoy most. Learn more about Colon

Discover the most popular places to visit in Colon

What to do in Colon

Colon Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $127 total per night from Aug 25 to Aug 26
$127 total
Aug 25 - Aug 26
Total includes taxes and fees
9/10 Wonderful! (4,148 reviews)
"The hotel is very clean, courteous staff and the location is central."

Reviewed on Aug 14, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $197 total per night from Sep 16 to Sep 17
$197 total
Sep 16 - Sep 17
Total includes taxes and fees
7.2/10 Good! (1,012 reviews)
Grandbaby’s 1st Family Vacay
"Loved to Italian n French food. Bed were very comfortable but pillows were too thick and uncomfortable. Didn’t get the Internet information to connect to. I got a taxi at the airport for my whole family cause it was cheaper than the resorts transportation."

Reviewed on Aug 14, 2025

Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Aug 18 to Aug 19
$111 total
Aug 18 - Aug 19
Total includes taxes and fees
9/10 Wonderful! (412 reviews)
"Nice hotel, lively lots of tourists/ music movement. convenient 24/7 coffee shop. walking distance from other restaurants/shops and night life"

Reviewed on Aug 15, 2025

Waymore Hotel Spa & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

Frequently asked questions

How much does a Colon vacation package cost?
You'll find cheap prices from $629 on Expedia for your Colon getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to Colon costs.
What are the cheapest months to go to Colon?
If you're hoping to score a cheap Colon vacation package, consider traveling in March, August and December. You'll generally find better rates on accommodations and flights during these months — perfect for a budget-friendly break.
How many days is enough for Colon?
You can see all the leading attractions in Colon within a few days, including the must-see Monument to Christopher Columbus. If you're after an extended Colon vacation, check out what kind of activities and day trips are available in the area.
Is it worth booking a vacation package to Colon?
Colon is a good vacation destination with attractions like Colon 2000 among the many things to keep you busy. Whether you're traveling with the family or getting away with friends, a Colon vacation promises a good time for everyone.
How to find the best Colon package deals?
Finding a cheap Colon package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most economical Colon package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Colon vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and hotels individually. Better still, you can personalize your Colon getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Colon?
Enjoy incredible bargains by reserving your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Colon trip.
How to plan a trip to Colon?

  1. Pick the ideal time to travel: Your schedule, favorite season and the type of weather you enjoy can all impact your decision on when to travel to Colon.
  2. Budget wisely: On top of the cost of your accommodations, you should factor in other expenses too. These include flights, transportation and food. Also, put aside a little extra for unexpected expenses that may crop up during your trip to Colon.
  3. Use Expedia's trip planning tool to discover Colon: Research every aspect of your trip to Colon with this handy planner. Invite friends or family to collaborate on a group getaway, search for hotels or things to do and make bookings.
  4. Work out your trip length: Think about how long you'd like to spend exploring Colon. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
  5. Bundle your airfare and accommodations: Once you've nailed down your travel dates and duration, book the perfect Colon vacation package for you.
  6. Add on excursions and experiences: Have a look at our travel guide to find some awesome things to do in Colon. Book tickets or make reservations as soon as you can to save time and avoid the stress of trying to find activities when you arrive.

Does Expedia offer Book Now, Pay Later Colon vacation packages?
Your Colon trip is meant to be a relaxing escape from your busy life, not a reason for money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.