Colon Vacations from $721
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Your Colon Vacation
With one of our vacation packages to Colon, you'll discover countless opportunities for fun and excitement. There's a lot to look forward to, including its lush beauty and laid-back lifestyle. If your trip to Colon includes a little sightseeing, don't miss much-loved attractions like Colon 2000, Monument to Christopher Columbus and Juventud Park. Your Colon vacation is clicks away. Explore hotels, airfares and more on Expedia for a trip that's tailored to suit your travel style.
The Latest Colon vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,244, price is now $1,108 per person
$1,108
per person
Nov 28 - Dec 5
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (997 reviews)
The jacuzzi in the room was terrible. Many, many times I tried but could not get it to work. Maintenance came multiple times, but they too had a hard time getting it to work.
Reviewed on Sep 9, 2025
Hotel Riu Plaza Panama
Bella Vista
Price was $1,240, price is now $816 per person
$816
per person
Nov 21 - Nov 28
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,277 reviews)
The cleanliness and well mannered staff and of course beautiful city view from the room.
Reviewed on Sep 20, 2025
Bristol Panama, a Registry Collection Hotel
Bella Vista
Save 100% on your flight
Price was $1,694, price is now $1,151 per person
$1,151
per person
Nov 21 - Nov 28
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,004 reviews)
Lovely people and great stay. Highly recommend
Reviewed on Sep 15, 2025
Where to stay in Colon
Find the best Colon areas and neighborhoods for the activities you enjoy most. Learn more about Colon
Cristobal
Travelers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area.
Discover the most popular places to visit in Colon
Gamboa Rainforest Resort
Explore the great outdoors at Gamboa Rainforest Resort, a lovely green space in Gamboa. While you're here, you can savor the top-notch restaurants.
Fort San Lorenzo
You can learn about the history of Colon with a stop at Fort San Lorenzo. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
Colon 2000
During your visit to Colon, you can search for that perfect souvenir at Colon 2000. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.
What to do in Colon
Panama Canal Monkey & Wildlife Boat Safari
$70
per adult
100% of travellers recommend
Panama City: Guided Jungle Adventure with Gatun Lake Cruise
$89
per adult
100% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
$42
per adult
100% of travellers recommend
Colon Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is $135 total per night from Sep 21 to Sep 22
$135 total
per night
Sep 21 - Sep 22
9/10 Wonderful! (4,282 reviews)
"Enjoyed the stay here. More quiet than other RIU locations I've been to"
Reviewed on Sep 19, 2025
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is $259 total per night from Sep 28 to Sep 29
$259 total
per night
Sep 28 - Sep 29
7.4/10 Good! (1,012 reviews)
"They offered everything! Loved our ocean view room! Staff was friendly and very accommodating!"
Reviewed on Sep 16, 2025
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is $99 total per night from Sep 21 to Sep 22
$99 total
per night
Sep 21 - Sep 22
9/10 Wonderful! (487 reviews)
1st solo trip- nailed it!!
"This was an awesome trip! The hotel was well worth the $$. The people were nice and the area was great! I will be back!!!"
Reviewed on Sep 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Hotels near Colon Free Zone
- Hotels near Colon Atlantic Passenger Station
- Hotels near Limon Bay
- Hotels near Enrique Adolfo Jimenez
- Beach Hotels in Fort Sherman
- Fort Sherman Hotels
- Hotels near Galeta Island Marine Education Center
- Cativa Hotels
- Lodges in Cativa
- Hotels near Gatun Locks
- Hotels near Canal Expansion Observation Center
- Sabanitas Hotels
- Flights from Enrique Adolfo Jimenez
- Flights from Panama City (PTY) to Colon (ONX)
- Flights from Miami (MIA) to Colon (ONX)
- Flights from San José (SJO) to Colon (ONX)
- Flights from Los Angeles (LAX) to Colon (ONX)
- Flights from New York (JFK) to Colon (ONX)
- Flights from Manila (MNL) to Colon (ONX)
- Flights from Houston (IAH) to Colon (ONX)
- Flights from Chicago (ORD) to Colon (ONX)
- Flights from San Francisco (SFO) to Colon (ONX)
- Flights to Enrique Adolfo Jimenez
- Flights from Denver (DEN) to Colon (ONX)
- Flights from Dallas (DFW) to Colon (ONX)
- Flights from Atlanta (ATL) to Colon (ONX)
- Flights from Tampa (TPA) to Colon (ONX)
- Flights from Seattle (SEA) to Colon (ONX)
- Flights from Fort Lauderdale (FLL) to Colon (ONX)
- Flights from Boston (BOS) to Colon (ONX)
- Flights from Las Vegas (LAS) to Colon (ONX)
- Flights from Philadelphia (PHL) to Colon (ONX)
- Flights from Phoenix (PHX) to Colon (ONX)
- Flights from Washington (IAD) to Colon (ONX)
- Flights from Baltimore (BWI) to Colon (ONX)
- Flights from Port of Spain (POS) to Colon (ONX)
- Flights from Minneapolis (MSP) to Colon (ONX)
- Flights from Mexico City (MEX) to Colon (ONX)
- Flights from Cartagena (CTG) to Colon (ONX)
- Flights from Balboa (BLB) to Colon (ONX)
- Flights from Tel Aviv (TLV) to Colon (ONX)
- Flights from Bocas del Toro (BOC) to Colon (ONX)
- Flights from Hartford (BDL) to Colon (ONX)
- Flights from Lima (LIM) to Colon (ONX)
- Flights from San Juan (SJU) to Colon (ONX)
- Flights from Oranjestad (AUA) to Colon (ONX)
- Flights from Cancun (CUN) to Colon (ONX)
- Flights from Bogotá (BOG) to Colon (ONX)
- Flights from Winnipeg (YWG) to Colon (ONX)
- Flights from Panama City (PAC) to Colon (ONX)
- Flights from Salt Lake City (SLC) to Colon (ONX)
- Flights from Quito (UIO) to Colon (ONX)
- Flights from Mumbai (BOM) to Colon (ONX)
- Flights from Geneva (GVA) to Colon (ONX)
- Flights from Knoxville (TYS) to Colon (ONX)
- Flights from Munich (MUC) to Colon (ONX)
- Flights from Providence (PVD) to Colon (ONX)
- Flights from Frankfurt (FRA) to Colon (ONX)
- Flights from London (LON) to Colon (ONX)
- Flights from San Salvador (SAL) to Colon (ONX)
- Flights from Guatemala City (GUA) to Colon (ONX)
- Flights from Punta Cana (PUJ) to Colon (ONX)
- Flights from Toronto (YYZ) to Colon (ONX)
- Flights from Buenos Aires (AEP) to Colon (ONX)
- Flights from Buenos Aires (EZE) to Colon (ONX)
- Flights from New York (NYC) to Colon (ONX)
- Flights from George Town (GCM) to Colon (ONX)
- Flights from Madrid (MAD) to Colon (ONX)
- Flights from Copenhagen (CPH) to Colon (ONX)
- Flights from Düsseldorf (DUS) to Colon (ONX)
- Flights from Oslo (OSL) to Colon (ONX)
- Flights from Guayaquil (GYE) to Colon (ONX)
- Flights from Barcelona (BCN) to Colon (ONX)
- Flights from Brussels (BRU) to Colon (ONX)
- Flights from Vitoria (VIX) to Colon (ONX)
- Flights from Warsaw (WAW) to Colon (ONX)
- Flights from Guadalajara (GDL) to Colon (ONX)
- Flights from Istanbul (IST) to Colon (ONX)
- Flights from Manchester (MAN) to Colon (ONX)
- Flights from Sarasota (SRQ) to Colon (ONX)
- Flights from Monterrey (MTY) to Colon (ONX)
- Flights from Stockholm (ARN) to Colon (ONX)
- Flights from Fort Sherman
- Flights to Cativa
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
