Colon Vacations from $716

Book a Hotel + Flight or Car together to unlock savings

Your Colon Vacation

With one of our vacation packages to Colon, you'll discover countless opportunities for fun and excitement. There's a lot to look forward to, including its lush beauty and laid-back lifestyle. If your trip to Colon includes a little sightseeing, don't miss much-loved attractions like Colon 2000, Monument to Christopher Columbus and Juventud Park. Your Colon vacation is clicks away. Explore hotels, airfares and more on Expedia for a trip that's tailored to suit your travel style.

The Latest Colon vacation packages

Price found within the past 48 hours. Click for updated prices.
Yoo Apartamento

Yoo Apartamento

3 out of 5
Bella Vista
Price was $979, price is now $716 per person
$716
per person
Oct 30 - Nov 4
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
10/10 Exceptional! (5 reviews)
The location and view are amazing! This is a great place to stay.

Reviewed on Jan 14, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,628, price is now $1,001 per person
$1,001
per person
Nov 3 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (974 reviews)
Everyone was very friendly and super helpful. Location was super convenient. Will definitely stay again.

Reviewed on Aug 20, 2025

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,087, price is now $765 per person
$765
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Casa Quijano 06 By Wynwood House

Casa Quijano 06 By Wynwood House

4 out of 5
Santa Ana
Price was $1,054, price is now $759 per person
$759
per person
Oct 30 - Nov 4
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.4/10 Exceptional! (3 reviews)
Easy to find, seamless check-in

Reviewed on Mar 21, 2025

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,016, price is now $738 per person
$738
per person
Nov 3 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (4,176 reviews)
My husband and I stayed at this property to celebrate our 12yr anniversary. The property, customer service and suite were amazing. The hotel is walkable to any great restaurants and shops. Additionally, the sushi and drinks at the lobby bar were delicious as well. I would definitely stay here again.

Reviewed on Aug 22, 2025

Don't see what you're looking for?
See all available trips from Columbus to Colon
View all trips

Where to stay in Colon

Find the best Colon areas and neighborhoods for the activities you enjoy most. Learn more about Colon
Default Image

Cristobal

Travelers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area.

Find hotels in Cristobal

Discover the most popular places to visit in Colon

Jungle Land Adventures - you may choose to kayak, swim or go fishing after you spend some time exploring the rain forest for wild life! www.panamaroadrunner.com

Gamboa Rainforest Resort

Explore the great outdoors at Gamboa Rainforest Resort, a lovely green space in Gamboa. While you're here, you can savor the top-notch restaurants.

Gamboa Rainforest Resort
Fort San Lorenzo

Fort San Lorenzo

You can learn about the history of Colon with a stop at Fort San Lorenzo. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.

Fort San Lorenzo

Colon 2000

During your visit to Colon, you can search for that perfect souvenir at Colon 2000. Stroll along this relaxing area's lakeside, or simply enjoy its restaurants.

Colon 2000

What to do in Colon

Gatun Lake boat ride

Panama Canal Monkey & Wildlife Boat Safari

$70
per adult
100% of travellers recommend
Panama Canal Monkey & Wildlife Boat Safari
Panama City: Guided Jungle Adventure with Gatun Lake Cruise

Panama City: Guided Jungle Adventure with Gatun Lake Cruise

$89
per adult
100% of travellers recommend
Panama City: Guided Jungle Adventure with Gatun Lake Cruise
Monkey and Sloth Jungle Habitat Panama Tour

Monkey and Sloth Jungle Habitat Panama Tour

$60
per adult
100% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
See all activities in Colon

Colon Hotel Deals

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

3.5 out of 5
Corregimiento de Cristobal, IA 5, Colon, Colon
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $148 total per night from Aug 29 to Aug 30
$148 total
Aug 29 - Aug 30
Total with taxes and fees
7.8/10 Good! (638 reviews)
"Good food, friendly staff, the free tours on offer are great too! Rooms comfy, overall a wonderful stay. Perhaps add a spa and maybe some more entertainment for guests on the weekend."

Reviewed on Aug 16, 2025

Gamboa Rainforest Reserve
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Aug 26 to Aug 27
$120 total
Aug 26 - Aug 27
Total with taxes and fees
9/10 Wonderful! (4,180 reviews)
"Its beautiful and clean"

Reviewed on Aug 21, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$217 nightly
The price is $217 total per night from Sep 7 to Sep 8
$217 total
Sep 7 - Sep 8
Total with taxes and fees
7.2/10 Good! (1,002 reviews)
"The room cleanliness was poor, as was the maintenance. The food options at the buffet were limited and sometimes of poor quality. Property is beautiful and safe. Staff were friendly and attentive."

Reviewed on Aug 19, 2025

Dreams Playa Bonita Panama - All Inclusive
See all 1,566 properties in Colon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Colon vacation package cost?
You'll find cheap prices from $716 on Expedia for your Colon getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to Colon costs.
What are the cheapest months to go to Colon?
If you're hoping to score a cheap Colon vacation package, consider traveling in March, August and December. You'll generally find better rates on accommodations and flights during these months — perfect for a budget-friendly break.
How many days is enough for Colon?
You can see all the leading attractions in Colon within a few days, including the must-see Monument to Christopher Columbus. If you're after an extended Colon vacation, check out what kind of activities and day trips are available in the area.
Is it worth booking a vacation package to Colon?
Colon is a good vacation destination with attractions like Colon 2000 among the many things to keep you busy. Whether you're traveling with the family or getting away with friends, a Colon vacation promises a good time for everyone.
How to find the best Colon package deals?
Finding a cheap Colon package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most economical Colon package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Colon vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and hotels individually. Better still, you can personalize your Colon getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Colon?
Enjoy incredible bargains by reserving your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Colon trip.
How to plan a trip to Colon?

  1. Pick the ideal time to travel: Your schedule, favorite season and the type of weather you enjoy can all impact your decision on when to travel to Colon.
  2. Budget wisely: On top of the cost of your accommodations, you should factor in other expenses too. These include flights, transportation and food. Also, put aside a little extra for unexpected expenses that may crop up during your trip to Colon.
  3. Use Expedia's trip planning tool to discover Colon: Research every aspect of your trip to Colon with this handy planner. Invite friends or family to collaborate on a group getaway, search for hotels or things to do and make bookings.
  4. Work out your trip length: Think about how long you'd like to spend exploring Colon. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
  5. Bundle your airfare and accommodations: Once you've nailed down your travel dates and duration, book the perfect Colon vacation package for you.
  6. Add on excursions and experiences: Have a look at our travel guide to find some awesome things to do in Colon. Book tickets or make reservations as soon as you can to save time and avoid the stress of trying to find activities when you arrive.

Does Expedia offer Book Now, Pay Later Colon vacation packages?
Your Colon trip is meant to be a relaxing escape from your busy life, not a reason for money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.