Colon Vacations from $762

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Your Colon Vacation

With one of our vacation packages to Colon, you'll discover countless opportunities for fun and excitement. There's a lot to look forward to, including its lush beauty and laid-back lifestyle. If your trip to Colon includes a little sightseeing, don't miss much-loved attractions like Colon 2000, Monument to Christopher Columbus and Juventud Park. Your Colon vacation is clicks away. Explore hotels, airfares and more on Expedia for a trip that's tailored to suit your travel style.

The Latest Colon vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Mio Panama

Hotel Mio Panama

Bella Vista
$762
per person
Oct 5 - Oct 9
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
8.6/10 Excellent! (222 reviews)
No one ever answers the hotel desk phone. No small "wash-cloths" in Panama. Hotel underground/ elevator parking is somewhat hair-raising to say the least. Overall I'll get it a 7 out to 10.

Reviewed on Aug 25, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
$1,125
per person
Oct 12 - Oct 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco. The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.

Reviewed on Sep 2, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
$845
per person
Nov 4 - Nov 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,692 reviews)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

Casco Viejo
Save 100% on your flight
$1,485
per person
Nov 12 - Nov 18
found 1 day ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (29 reviews)
Nice apartment ! Clean and great location

Reviewed on Aug 13, 2026

Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
$839
per person
Nov 4 - Nov 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.6/10 Excellent! (1,716 reviews)
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Where to stay in Colon

Find the best Colon areas and neighborhoods for the activities you enjoy most. Learn more about Colon
An aerial view of a coastal area with a large body of water, a bridge, and a solar power plant.

Barrio Sur

3 out of top 10 points of interest in this area

If you're spending some time in Barrio Sur, Colon Free Zone and Colon 2000 are top sights worth seeing.

A statue of a historical figure pointing upwards with a bird in hand, set against a backdrop of a clear blue sky with scattered clouds.

Barrio Norte

1 out of top 10 points of interest in this area

While visiting Barrio Norte, you might make a stop by sights like Monument to Christopher Columbus and Limon Bay.

A canal with a lock system, a large cargo ship, and a white building with "PANAMA CANAL" written on it.

Cristobal

Travelers enjoy Cristobal for its churches and seaside views. Consider checking out Limon Bay while you're in the area.

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Coco Solo

If you're spending some time in Coco Solo, Colon Free Zone and Limon Bay are top sights worth seeing.

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Gatun

The museums and monuments are just a few features travelers like about Gatun. If you want to do some sightseeing nearby, Canal Expansion Observation Center and Gatún Dam are a few top places to visit.

Stay near popular Colon attractions

Fort San Lorenzo

8.4/10 (36 reviews)
Perched dramatically above the Caribbean Sea, Fort San Lorenzo guarded Spanish treasure routes from pirates in the 17th century. Explore its UNESCO-protected walls while enjoying sweeping coastal views.
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Colon 2000

7.6/10 (88 reviews)
This bustling cruise port welcomes travelers with duty-free shopping and local cuisine. Browse handcrafted souvenirs or savor regional dishes while preparing for your Caribbean or Panama Canal adventure.
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Gamboa Rainforest Resort

8.4/10 (571 reviews)
Nestled in Panama's Soberanía National Park, Gamboa Rainforest Resort provides a luxury wilderness retreat. Experience the canopy via aerial tram or spot wildlife on boat tours along the Panama Canal.
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Galeta Island Marine Education Center

8.2/10 (21 reviews)
This Smithsonian facility showcases Panama's Caribbean coastal ecosystems through guided mangrove walks and touch pools. Explore the rooftop deck for views of wildlife and the Panama Canal entrance.
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Canal Expansion Observation Center

9.2/10 (34 reviews)
Witness the engineering marvel of Panama's expanded canal from panoramic platforms at the Agua Clara Locks. Watch massive Neo-Panamax ships navigate while learning about this feat through informative exhibits.
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Monument to Christopher Columbus

8.2/10 (21 reviews)
This bronze statue honors Columbus's voyages with a dramatic pose symbolizing the meeting of worlds. Stroll along the Paseo del Centenario for Caribbean Sea views and contemplative moments at this historic monument.
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Fantastic Casino | Colón 2000

This 24-hour gaming destination offers an energetic atmosphere with diverse electronic games and slot machines. Relax between plays at the on-site restaurant and bar while experiencing Panama's vibrant casino culture.
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November 5 Park

6.4/10 (7 reviews)
Parque 5 de Noviembre commemorates Colón's rebirth after the devastating 1940 fire with Spanish-inspired architecture. Stroll among fan-shaped palms and enjoy cultural concerts at the historic bandshell.
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What to do in Colon

Monkey and Sloth Jungle Habitat Panama Tour

Monkey and Sloth Jungle Habitat Panama Tour

$42
per adult
96% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
Magnificent Gatun lake

Monkey Watch and Gatun Lake Wildlife Safari Private Tour

$75
per adult
Monkey Watch and Gatun Lake Wildlife Safari Private Tour
Explore Panama Canal and Gatun Lake with Rainforest Hike

Explore Panama Canal and Gatun Lake with Rainforest Jungle Walk

$109
per adult
Explore Panama Canal and Gatun Lake with Rainforest Jungle Walk
See all activities in Colon

Colon Hotel Deals

SAND DIAMOND HOTEL

SAND DIAMOND HOTEL

Millennium Plaza, Av A. Waked Colon Colon
Fully refundable
$105 nightly
$116 total
Sep 3 - Sep 4
Total with taxes and fees
8.6/10 Excellent! (298 reviews)
"El hotel limpió la atención buena el acceso a zona libre genial. no tienen buenas opciones para el desayuno casi nada de comer todo muy limitado"

Reviewed on Aug 29, 2026

SAND DIAMOND HOTEL
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

Corregimiento de Cristobal, IA 5 Colon Colon
Fully refundableReserve now, pay when you stay
$131 nightly
$144 total
Sep 10 - Sep 11
Total with taxes and fees
8/10 Very Good! (802 reviews)
"Only stayed one night, but there is way too much to see and do, so wish I'd stayed longer! Beautiful property, amazing location, so much nature to explore!"

Reviewed on Aug 31, 2026

Gamboa Rainforest Reserve
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$123 nightly
$135 total
Sep 28 - Sep 29
Total with taxes and fees
Hotel Riu Plaza Panama
See all 1,868 properties in Colon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Colon Vacation Packages

Colon Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
76,600
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Canal Expansion Observation Center, Parque Nacional San Lorenzo and Safaricks Zoo

More vacations you might like

Frequently asked questions

How much does a Colon vacation package cost?
You'll find cheap prices from $762 on Expedia for your Colon getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to Colon costs.
What are the cheapest months to go to Colon?
If you're hoping to score a cheap Colon vacation package, consider traveling in March, August and December. You'll generally find better rates on accommodations and flights during these months — perfect for a budget-friendly break.
How many days is enough for Colon?
You can see all the leading attractions in Colon within a few days, including the must-see Monument to Christopher Columbus. If you're after an extended Colon vacation, check out what kind of activities and day trips are available in the area.
Is it worth booking a vacation package to Colon?
Colon is a good vacation destination with attractions like Colon 2000 among the many things to keep you busy. Whether you're traveling with the family or getting away with friends, a Colon vacation promises a good time for everyone.
How to find the best Colon package deals?
Finding a cheap Colon package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and browse what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most economical Colon package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Colon vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and hotels individually. Better still, you can personalize your Colon getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Colon?
Enjoy incredible bargains by reserving your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Colon trip.
How to plan a trip to Colon?
  1. Pick the ideal time to travel: Your schedule, favorite season and the type of weather you enjoy can all impact your decision on when to travel to Colon.
  2. Budget wisely: On top of the cost of your accommodations, you should factor in other expenses too. These include flights, transportation and food. Also, put aside a little extra for unexpected expenses that may crop up during your trip to Colon.
  3. Use Expedia's trip planning tool to discover Colon: Research every aspect of your trip to Colon with this handy planner. Invite friends or family to collaborate on a group getaway, search for hotels or things to do and make bookings.
  4. Work out your trip length: Think about how long you'd like to spend exploring Colon. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
  5. Bundle your airfare and accommodations: Once you've nailed down your travel dates and duration, book the perfect Colon vacation package for you.
  6. Add on excursions and experiences: Have a look at our travel guide to find some awesome things to do in Colon. Book tickets or make reservations as soon as you can to save time and avoid the stress of trying to find activities when you arrive.
Does Expedia offer Book Now, Pay Later Colon vacation packages?
Your Colon trip is meant to be a relaxing escape from your busy life, not a reason for money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.