Cairo Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Cairo Vacation

The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.

Discover the most popular places to visit in Cairo

Cairo Hotel Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Mar 1 to Mar 2
$81 total
Mar 1 - Mar 2
Total with taxes and fees
6.4/10 (275 reviews)
Break fast was excellent

Reviewed on Sep 28, 2025

Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Feb 3 to Feb 4
$69 total
Feb 3 - Feb 4
Total with taxes and fees
6.6/10 (621 reviews)
Affordable for a quick one night stay. Restaurant and gas station next to hotel.

Reviewed on Jan 20, 2026

Super 8 by Wyndham Charleston/Sikeston East MO
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL
$133 nightly
The price is $140 total per night from Feb 3 to Feb 4
$140 total
Feb 3 - Feb 4
Total with taxes and fees
9.8/10 Exceptional! (34 reviews)
The cabin was great

Reviewed on Dec 1, 2025

Cozy cabins on beautiful Horseshoe Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Cairo Vacation Packages

Things to do near Cairo

Cairo, Illinois, offers a perfect getaway for outdoor enthusiasts and adventure seekers with its beautiful campgrounds and recreational areas. Visitors can enjoy various activities while exploring the scenic landscapes. For those interested in travel, there are options for tours, including connections to Cairo, Egypt, and available packages like the Luxor tour. Make sure to take advantage of local tour guides to enhance your experience.

Shopping

Cairo offers a unique shopping experience with local shops and boutiques downtown. For more options, if you're up for a drive, visit the nearby Cape Girardeau Mall, featuring a variety of retail stores and dining options, or the West Park Mall in Jackson for additional shopping opportunities.

Recreation

Experience ultimate relaxation at eDen Spa & Salon, located 28 miles from Cairo. Enjoy rejuvenating body treatments in a serene atmosphere, perfect for unwinding and recharging your spirit. Indulge in soothing massages and luxurious spa services that promote wellness and tranquility.

Adventure

Experience excitement at Cape Splash Family Aquatic Center, located 31 miles from Cairo, where thrilling water slides and family fun await. For outdoor enthusiasts, hike the Limekin Springs Trail, situated 20 miles away, offering stunning scenery and adventure in a serene natural environment.

Nightlife

Cairo's nightlife offers a unique blend of local charm. Visit The Delta Restaurant for Southern cuisine and enjoy live music. The Riverfront Park provides a scenic backdrop for evening strolls, while local bars showcase regional drinks, creating a relaxed atmosphere perfect for unwinding after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in and around Cairo

Cairo, Illinois, offers a delightful blend of outdoor adventure and scenic beauty, perfect for vacationers seeking culture and exploration. Discover national parks, historic forts, and nature reserves that showcase the area's rich heritage. Don't miss out on Cairo's tourist attractions, including tours of historic sites and local museums. Whether you're interested in adventure or simply soaking in the sights, Cairo has something for everyone to enjoy.

  • Fort Defiance State Park: Explore the rich history of Fort Defiance State Park, where visitors can learn about its significance during the Civil War. Enjoy scenic views of the confluence of the Ohio and Mississippi Rivers, while experiencing the park's cultural vibes through its historic landmarks and walking trails.
  • Columbus-Belmont State Park: Located 17 miles from Cairo, this national park offers adventure and stunning scenery. Engage in outdoor activities like hiking, fishing, and picnicking, all while soaking in the picturesque landscapes and learning about its Civil War history.
  • Ullin City Hall: Situated 19 miles away, Ullin City Hall is a charming civic center showcasing friendly local vibes. Take a stroll through the nearby area, where you can meet welcoming residents and experience the small-town atmosphere.

Best time to go to Cairo

The best time to visit Cairo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Cairo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Cairo falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighAverage
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

Tips to save on your trip to Cairo

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Cairo during the low season (November to January) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Cairo Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cape Girardeau Municipal Airport (CGI)
Population
2,500
Max Temp Winter
45ºF
Max Temp Summer
85ºF

More vacations you might like

Frequently asked questions

How much does a Cairo vacation package cost?
Offering great value package deals on Expedia, you'll be pleasantly surprised at how much a vacation to Cairo costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Cairo?
If you'd like to snag a cheap Cairo vacation package, consider planning a trip in December, January and February. You'll typically find lower prices on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Cairo?
The ideal duration for your Cairo vacation depends on what you'd like to do. Generally, a few days to a week will give you plenty of time to go to all the major attractions and explore some hidden treasures along the way.
How to find the best Cairo package deals?
Landing a cheap Cairo package deal is a cinch with Expedia. Once you've entered your trip dates and destination under our "Packages" tab, set your budget range, apply some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most economical Cairo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Cairo vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Cairo escape to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Cairo?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment Cairo break.
Does Expedia offer Book Now, Pay Later Cairo vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Cairo vacation across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.