Cairo Vacations from $804

Book a Hotel + Flight or Car together to unlock savings

Your Cairo Vacation

The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.

The Latest Cairo vacation packages

Price found within the past 48 hours. Click for updated prices.
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

3.5 out of 5
Price was $865, price is now $804 per person
$804
per person
Jan 16 - Jan 20
found 9 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Paducah (PAH)
8.2/10 Very Good! (1,000 reviews)
It was a good time with the girls

Reviewed on Dec 11, 2025

Marcs Museum

Marcs Museum

3 out of 5
Price was $2,106, price is now $1,806 per person
$1,806
per person
Mar 6 - Mar 11
found 23 hours ago
Roundtrip flight included
Augusta (AGS) to Paducah (PAH)
No reviews
Comfort Suites

Comfort Suites

2.5 out of 5
Price was $1,596, price is now $1,477 per person
$1,477
per person
Mar 6 - Mar 11
found 23 hours ago
Roundtrip flight included
Augusta (AGS) to Paducah (PAH)
8.6/10 Excellent! (900 reviews)
Staff was friendly. Room very clean.

Reviewed on Dec 16, 2025

Homewood Suites By Hilton Paducah

Homewood Suites By Hilton Paducah

3 out of 5
Price was $1,792, price is now $1,659 per person
$1,659
per person
Mar 6 - Mar 11
found 23 hours ago
Roundtrip flight included
Augusta (AGS) to Paducah (PAH)
9.4/10 Exceptional! (391 reviews)
The staff was amazing, the room was in great condition, and the breakfast was better than most I've been to. The patio is really nice. I don't think the pool is heated though, but it was indoors and refreshing.

Reviewed on Nov 30, 2025

The Respite Bed and Breakfast

The Respite Bed and Breakfast

4.5 out of 5
Price was $944, price is now $876 per person
$876
per person
Jan 16 - Jan 20
found 9 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Paducah (PAH)
9.8/10 Exceptional! (270 reviews)
Hidden gem! What a wonderful, comfortable stay. Our room was spacious and very well laid out. The bed and pillows were ultra comfortable. I loved the breakfast, it was so delicious with lots of choices and good coffee. The house is beautiful, a cool addition is the billiards room hidden behind a bookcase. So chic.

Reviewed on Dec 12, 2025

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Discover the most popular places to visit in Cairo

Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

Fort Defiance State Park

Cairo Hotel Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Jan 10 to Jan 11
$81 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
6.4/10 (273 reviews)
Break fast was excellent

Reviewed on Sep 28, 2025

Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Dec 18 to Dec 19
$69 total
Dec 18 - Dec 19
Total with taxes and fees
6.6/10 (611 reviews)
Thank you

Reviewed on Nov 7, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St Charleston MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Dec 23 to Dec 24
$73 total
Dec 23 - Dec 24
Total with taxes and fees
6.8/10 (406 reviews)
Ladydi
The only issue was the temperature display on the ac/heating unit went to E5 during the night and it was overly warm. I woke up because of this and was able to get the fan only running but it was still uncomfortable for me and I spent 5 hours tossing and turning with little sleep after that with ...

Reviewed on Oct 22, 2025

Quality Inn Charleston - Sikeston
See all 25 properties in Cairo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Cairo Vacation Packages

Cairo Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cape Girardeau Municipal Airport (CGI)
Population
2,500
Max Temp Winter
45ºF
Max Temp Summer
85ºF

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Frequently asked questions

How much does a Cairo vacation package cost?
Offering great value package deals from $804 on Expedia, you'll be pleasantly surprised at how much a vacation to Cairo costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Cairo?
If you'd like to snag a cheap Cairo vacation package, consider planning a trip in December, January and February. You'll typically find lower prices on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Cairo?
The ideal duration for your Cairo vacation depends on what you'd like to do. Generally, a few days to a week will give you plenty of time to go to all the major attractions and explore some hidden treasures along the way.
How to find the best Cairo package deals?
Landing a cheap Cairo package deal is a cinch with Expedia. Once you've entered your trip dates and destination under our "Packages" tab, set your budget range, apply some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most economical Cairo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Cairo vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Cairo escape to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Cairo?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment Cairo break.
Does Expedia offer Book Now, Pay Later Cairo vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Cairo vacation across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.