Title: The Best Hotels Closest to Fort Defiance State Park in Cairo for 2026 | Expedia.com [Cairo Travel Guide](https://expedia.com/Cairo.dx6626)[Vacation Rentals in Cairo](https://expedia.com/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.com/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Car Rentals in Fort Defiance State Park](https://expedia.com/Car-Rentals-In-Fort-Defiance-State-Park.d6091411.Car-Rental-Guide)[Fort Defiance State Park Vacations](https://expedia.com/Fort-Defiance-State-Park-Cairo.d6091411.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=6091411&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 28 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6091411&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6091411&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6091411&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Fort Defiance State Park hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/96f1c1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/e2b2c624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) 4.8 mi from Fort Defiance State Park 6.6/10 (282 reviews) "The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ReShena $68 nightly $76 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) 10.9 mi from Fort Defiance State Park 6.8/10 (625 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/08c2ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/a42cb957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cf3c3f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/9e3a2899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel Charleston-Sikeston [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) 12.6 mi from Fort Defiance State Park 6.8/10 (408 reviews) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo $70 nightly $78 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) 10 mi from Fort Defiance State Park 6.6/10 (105 reviews) "Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcelle $64 nightly $71 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/e95f9062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Free WiFi](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/1016c5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/f3adf3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Center Motel [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) 10.9 mi from Fort Defiance State Park 7.8/10 Good (17 reviews) "Quiet and convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alma $56 nightly $60 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-13&endDate=2026-03-14®ionId=6091411&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Fort Defiance State Park | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ----------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Quality Inn Cairo I-57 | 2.5 star property | 6.6282 reviews | View | | | | | | | ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Super 8 by Wyndham Charleston/Sikeston East MO | 2.0 star property | 6.8625 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/08c2ace2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Riverstone Hotel Charleston-Sikeston | 2.5 star property | 6.8408 reviews | View | | | | | | | ![Room, 1 King Bed, Non Smoking \| View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Eagle Inn Charleston | 2.0 star property | 6.6105 reviews | View | | | | | | | ![Basic Double Room \| Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/e95f9062.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Center Motel | 2.0 star property | 7.8Good17 reviews | View | | | | | | ## Top Fort Defiance State Park Hotel Reviews ![Drury Inn Paducah](https://images.trvl-media.com/lodging/1000000/50000/42500/42447/2d58db7a_y.jpg) ### Drury Inn Paducah 10/10 Excellent "room was very clean and nice. dinner and breakfast was good." [](https://expedia.com/Paducah-Hotels-Drury-Inn-Paducah.h42447.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Yes" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Great clean and quiet room " [](https://expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. 10/10 Excellent "Would recommend this place to any one who is going there. Very clean." [](https://expedia.com/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![Comfort Inn & Suites Sikeston I-55](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2_y.jpg) ### Comfort Inn & Suites Sikeston I-55 10/10 Excellent "facility was very clean. night staff was a pleasure and most helpful. very nice room with lots of space. great stay! good breakfast as well." [](https://expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Very nice folks who manage the hotel!!" [](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg) ### Super 8 by Wyndham Sikeston/Miner Area 10/10 Excellent "The room was spotless, the staff was very good and helpful. I loved my stay. I recommend Drury Inn to all my family and friends. " [](https://expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.](https://images.trvl-media.com/lodging/90000000/89700000/89695000/89694914/af43b2b3_y.jpg) ### Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer. 10/10 Excellent "Glad to have this home to stay in as it was very close to where we needed to be. It was older but clean, warm and comfortable. The owner was great. " [](https://expedia.com/Next-Door-To-Wildlife-Mgmt-Area-Full-Kitchen.h89694914.Hotel-Information) ![Drury Inn & Suites Paducah](https://images.trvl-media.com/lodging/1000000/50000/42500/42450/w3837h2560x3y0-d7f24a86_y.jpg) ### Drury Inn & Suites Paducah 10/10 Excellent "Room was clean, staff was extremely courteous! Meal was very good. The only thing was the noise level so close to the freeway. Had a hard time falling asleep, but once I did it was fine. " [](https://expedia.com/Paducah-Hotels-Drury-Inn-Suites-Paducah.h42450.Hotel-Information) ## Hotels near other Fort Defiance State Park attractions ### Columbus-Belmont State Park 3.7/5 (18 reviews) You can learn about the history of Columbus with a stop at Columbus-Belmont State Park. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6091579) ### Ullin City Hall After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6187204) ### Limekin Springs Trail Trailhead You can take time to visit Limekin Springs Trail Trailhead during your travels to Ullin. Make some time to visit the shops while you're in the area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=641530566247731200) ### Front Street Studio & Art Gallery 4.2/5 (9 reviews) You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655753) ### Lower Cache River Access Area You can take time to visit Lower Cache River Access Area during your travels to Cypress. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=877134620821561344) ### City of Miner Convention Center Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=818566100963352576) ### Henry N Barkhausen Cache River Wetlands Center You can spend time studying the exhibits at Henry N Barkhausen Cache River Wetlands Center during your travels in Cypress. Amble around the area's parks or experience its museums. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655797) ## Frequently asked questions ### What are the top-rated hotels near Fort Defiance State Park? > [Quality Inn Cairo I-57](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) > > > Quality Inn Cairo I-57 offers a comfortable retreat just 5.0 miles from Fort Defiance State Park, making it an ideal choice for those exploring the area. Rated 6.6 by travelers, this hotel provides essential amenities such as free daily breakfast and air conditioning for a pleasant stay. Guests can take advantage of the in-room kitchen, complete with a refrigerator and microwave, perfect for preparing meals. The hotel also features free parking for RVs and trucks, ensuring convenient access for all travelers. ### How much is a hotel near Fort Defiance State Park? ### What are the most popular family-friendly hotels near Fort Defiance State Park? > [Quality Inn Cairo I-57](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) > > > Quality Inn Cairo I-57 is a family-friendly hotel located just 5.0 miles from Fort Defiance State Park. With a review rating of 6.6, this hotel provides essential amenities for families, including free cribs and a fully equipped kitchen. Guests can enjoy a complimentary full breakfast daily, making mornings straightforward. Additional amenities include free parking and air-conditioned rooms, ensuring a comfortable stay for everyone. ### What are the best affordable hotels near Fort Defiance State Park? > [Quality Inn Cairo I-57](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) > > > Quality Inn Cairo I-57 is a convenient choice located just 5.0 miles from Fort Defiance State Park, a review rating of 6.6\. This hotel offers family-friendly amenities such as free cribs and breakfast options to make traveling with children easier. Guests can enjoy complimentary WiFi, air conditioning, and access to a microwave and refrigerator in the rooms, ensuring a comfortable stay for families. With free self-parking and daily housekeeping, this hotel combines affordability and essential conveniences for a pleasant getaway. ### What are the best pet-friendly hotels near Fort Defiance State Park? > [Quality Inn Cairo I-57](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) > > > Quality Inn Cairo I-57 is just 5.0 miles from Fort Defiance State Park and has a welcoming atmosphere for travelers with pets. This 2-star hotel allows pets, ensuring a pleasant stay for both travelers and their furry companions. With a review rating of 6.6, it features convenient amenities like free breakfast, air conditioning, and in-room kitchen facilities, including a refrigerator and microwave. The hotel also provides free parking and early check-in, making it a practical choice for families and pet owners. ### Can I book a fully refundable hotel close to Fort Defiance State Park? ### Can I find Expedia discounts for hotels near Fort Defiance State Park? > *\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.* ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Cairo Hotels ](https://www.expedia.com/Cairo-Hotels.d6626.Travel-Guide-Hotels) - [Historic Hotels in Cairo ](https://www.expedia.com/Cairo-Hotels-Historic-Hotel.0-0-d6626-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Cairo ](https://www.expedia.com/Cairo-Hotels-Luxury-Hotel.0-0-d6626-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Cairo ](https://www.expedia.com/Cairo-Hotels-Hotels-With-Restaurants.0-0-d6626-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Cairo ](https://www.expedia.com/Cairo-Hotels-Cheap-Hotels.0-0-d6626-tCheapHotels.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Cairo ](https://www.expedia.com/5Star-Cairo-Hotels.s50-0-d6626.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Cairo ](https://www.expedia.com/Cairo-Cabins.d6626-aaCabins.Travel-Guide-Accommodation) - [Hotels with a Pool in Cairo ](https://www.expedia.com/Cairo-Hotels-Hotel-With-Pool.0-0-d6626-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Cairo ](https://www.expedia.com/Cairo-Hotels-Wyndham-Hotels.0-0-d6626--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Cottages in Cairo ](https://www.expedia.com/Cairo-Cottages.d6626-aaCottages.Travel-Guide-Accommodation) - [4 Star Hotels in Cairo ](https://www.expedia.com/4Star-Cairo-Hotels.s40-0-d6626.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Cairo ](https://www.expedia.com/Cairo-Hotels-Pet-Friendly-Hotel.0-0-d6626-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Motels in Cairo ](https://www.expedia.com/Cairo-Motels.d6626-aaMotels.Travel-Guide-Accommodation) - [Hotels near Cairo Regional ](https://www.expedia.com/Cairo-Regional-Airport-Hotels.0-aCIR-0.Travel-Guide-Filter-Hotels) - [Mound City Hotels ](https://www.expedia.com/Mound-City-Hotels.d3000434585.Travel-Guide-Hotels) - [Hotels near Mound City National Cemetery ](https://www.expedia.com/Mound-City-National-Cemetery-Hotels.0-l553248621555594730-0.Travel-Guide-Filter-Hotels) - [Flights to Cairo ](https://www.expedia.com/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights) - [Flights from Cairo ](https://www.expedia.com/lp/flights/6626/flights-from-cairo) - [Nashville to Cairo ](https://www.expedia.com/lp/flights/178291/6626/nashville-to-cairo) - [Chicago to Cairo ](https://www.expedia.com/lp/flights/178248/6626/chicago-to-cairo) - [Flights from Cairo Regional ](https://www.expedia.com/lp/airports/cir/flights-from-cairo-regional-airport) - [Flights from Chicago (ORD) to Cairo (CIR) ](https://www.expedia.com/lp/flights/ord/cir/chicago-to-cairo) - [Flights from Minneapolis (MSP) to Cairo (CIR) ](https://www.expedia.com/lp/flights/msp/cir/minneapolis-to-cairo) - [Flights from Brownsville (BRO) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bro/cir/brownsville-to-cairo) - [Flights from Miami (MIA) to Cairo (CIR) ](https://www.expedia.com/lp/flights/mia/cir/miami-to-cairo) - [Flights from Los Angeles (LAX) to Cairo (CIR) ](https://www.expedia.com/lp/flights/lax/cir/los-angeles-to-cairo) - [Flights from Boston (BOS) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bos/cir/boston-to-cairo) - [Flights from Nashville (BNA) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bna/cir/nashville-to-cairo) - [Flights from Kansas City (MCI) to Cairo (CIR) ](https://www.expedia.com/lp/flights/mci/cir/kansas-city-to-cairo) - [Flights from Dallas (DFW) to Cairo (CIR) ](https://www.expedia.com/lp/flights/dfw/cir/dallas-to-cairo) - [Flights from Gulfport (GPT) to Cairo (CIR) ](https://www.expedia.com/lp/flights/gpt/cir/gulfport-to-cairo) - [Flights from Greenville (GSP) to Cairo (CIR) ](https://www.expedia.com/lp/flights/gsp/cir/greenville-to-cairo) - [Flights from Beirut (BEY) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bey/cir/beirut-to-cairo) - [Flights from Tampa (TPA) to Cairo (CIR) ](https://www.expedia.com/lp/flights/tpa/cir/tampa-to-cairo) - [Flights from Pittsburgh (PIT) to Cairo (CIR) ](https://www.expedia.com/lp/flights/pit/cir/pittsburgh-to-cairo) - [Flights from Denver (DEN) to Cairo (CIR) ](https://www.expedia.com/lp/flights/den/cir/denver-to-cairo) - [Flights from Barranquilla (BAQ) to Cairo (CIR) ](https://www.expedia.com/lp/flights/baq/cir/barranquilla-to-cairo) - [Flights from Baltimore (BWI) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bwi/cir/baltimore-to-cairo) - [Flights from St. Louis (CPS) to Cairo (CIR) ](https://www.expedia.com/lp/flights/cps/cir/st-louis-to-cairo) - [Flights from Cairo (CAI) to Cairo (CIR) ](https://www.expedia.com/lp/flights/cai/cir/cairo-to-cairo) - [Flights from Atlanta (ATL) to Cairo (CIR) ](https://www.expedia.com/lp/flights/atl/cir/atlanta-to-cairo) - [Flights from Sault Ste. 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