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Our top choices for Fort Defiance State Park hotels

A large hotel with a prominent sign reading "Harriss" and a decorative archway with lights.
A modern bar area with a long counter, bar stools, and a wooden ceiling.
A casino bar with multiple gaming machines, a central bar area with stools, and a patterned carpet.
A Harrah's Metropolis casino bar area with multiple gaming tables, a well-stocked liquor shelf, and bar stools.

1. Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
25.2 mi from Fort Defiance State Park
United States
Jason
$115 nightly
$128 total
Sep 20 - Sep 21
Total with taxes and fees
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
A hotel lobby with a reception desk, seating area, and a large window.
A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.
A hotel room with a desk, chair, television, and a lamp.

2. Quality Inn Cairo I-57

Quality Inn Cairo I-57
4.8 mi from Fort Defiance State Park
United States
Santiago
$70 nightly
$78 total
Oct 2 - Oct 3
Total with taxes and fees
Quality Inn Cairo I-57
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.

3. The Riverview

The Riverview
30.6 mi from Fort Defiance State Park
United States
Alyssa
$104 nightly
$117 total
Oct 12 - Oct 13
Total with taxes and fees
The Riverview
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

4. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
30.5 mi from Fort Defiance State Park
United States
Kristin
$125 nightly
$142 total
Sep 27 - Sep 28
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
22.6 mi from Fort Defiance State Park
United States
Scott Andrew
$102 nightly
$117 total
Sep 17 - Sep 18
Total with taxes and fees
Drury Inn & Suites Sikeston, MO
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

6. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
26.1 mi from Fort Defiance State Park
United States
Allen
$101 nightly
$114 total
Sep 20 - Sep 21
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

7. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
26.1 mi from Fort Defiance State Park
United States
Lauren
$109 nightly
$123 total
Oct 11 - Oct 12
Total with taxes and fees
TownePlace Suites by Marriott Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A buffet with various food items, including omelets and baked goods, served in metal containers.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
25.7 mi from Fort Defiance State Park
United States
michael
$98 nightly
$111 total
Oct 11 - Oct 12
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

9. Hampton Inn Sikeston

Hampton Inn Sikeston
26 mi from Fort Defiance State Park
United States
Jeffrey
$102 nightly
$115 total
Oct 11 - Oct 12
Total with taxes and fees
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

10. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
22.3 mi from Fort Defiance State Park
United States
Bernice
$87 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A reception area with a sign for 'Travel Inn and Suites'.
A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.

11. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
22.6 mi from Fort Defiance State Park
United States
Sharika West
$58 nightly
$66 total
Sep 13 - Sep 14
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

12. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
22.6 mi from Fort Defiance State Park
United States
Lakeysha
$89 nightly
$101 total
Oct 4 - Oct 5
Total with taxes and fees
Comfort Inn & Suites Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

13. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
22.4 mi from Fort Defiance State Park
United States
Val
$65 nightly
$75 total
Sep 22 - Sep 23
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

14. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
22.8 mi from Fort Defiance State Park
United States
Kevin
$57 nightly
$65 total
Sep 20 - Sep 21
Total with taxes and fees
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.
A motel with a red roof and beige walls, a parking lot, and a signboard.
A compact room with a television on a cabinet, a microwave, a small refrigerator, a table, and a chair.

15. La Center Motel

La Center Motel
10.9 mi from Fort Defiance State Park
United States
Carrie
$65 nightly
$70 total
Sep 20 - Sep 21
Total with taxes and fees
La Center Motel
A building with a fountain and flower beds in front.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

16. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
12.6 mi from Fort Defiance State Park
United States
Jay
$65 nightly
$73 total
Sep 22 - Sep 23
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

17. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
10.9 mi from Fort Defiance State Park
United States
France
$59 nightly
$65 total
Sep 22 - Sep 23
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

18. Eagle Inn Charleston

Eagle Inn Charleston
10 mi from Fort Defiance State Park
United States
Jackson
$77 nightly
$85 total
Sep 12 - Sep 13
Total with taxes and fees
Eagle Inn Charleston
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A reception area with a counter, a coffee machine, and seating.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

19. Country Yard Inn and Suite

Country Yard Inn and Suite
22.3 mi from Fort Defiance State Park
United States
William
$56 nightly
$63 total
Oct 11 - Oct 12
Total with taxes and fees
Country Yard Inn and Suite
An indoor swimming pool with wooden walls and stone accents, surrounded by seating areas and a balcony.
A gym with treadmills, ellipticals, and a stationary bike.
A conference room with a stage, chairs, and a carpeted floor.
A reception desk with a wooden finish and granite top, a sign above it reading "Baymont Inn & Suites," and a stone wall in the background.

20. Baymont by Wyndham Metropolis

Baymont by Wyndham Metropolis
25.3 mi from Fort Defiance State Park
United States
Julee
Baymont by Wyndham Metropolis
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Compare popular hotels close to Fort Defiance State Park

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
La Center Motel
7.6
Good
22 reviews
View
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
Super 8 by Wyndham Charleston/Sikeston East MO
6.8
666 reviews
View
A building with a fountain and flower beds in front.
The Riverstone Hotel Charleston-Sikeston
6.8
432 reviews
View
A hotel lobby with a reception desk, seating area, and a large window.
Quality Inn Cairo I-57
6.4
295 reviews
View
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
Eagle Inn Charleston
6.6
107 reviews
View

Top Fort Defiance State Park Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Canceled"
Crystal 4-night trip
Posted 6 hours ago
Super 8 by Wyndham Charleston/Sikeston East MO
Wandering the wineries or hitting the hills? We got you! Come stay!

Wandering the wineries or hitting the hills? We got you! Come stay!

10/10 Excellent
"This is the 2nd time staying here and location is perfect for exploring Cache River. Brent and Wendy are amazing hosts and excellent at communicating. Already booked in November to come back for a week of relaxing with friends and doing some hunting. I highly recommend staying here if you want something clean, good communication and great location."
David P. 3-night trip
Posted 20 hours ago
Wandering the wineries or hitting the hills? We got you! Come stay!
Drury Inn & Suites Paducah

Drury Inn & Suites Paducah

8/10 Good
"Overall nice, quality hotel. The complementary food and kickback hour is very nice. The pool and hot tub were clean and maintained."
Caitlyn 1-night trip
Posted 20 hours ago
Drury Inn & Suites Paducah
Quality Inn Cairo I-57

Quality Inn Cairo I-57

8/10 Good
"Good service,nice stuff and no complaints"
Santiago 1-night trip
Posted 23 hours ago
Quality Inn Cairo I-57
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"All good, staff friendly and helpful! Breakfast was great and kick back dinner was good!"
Randy 1-night trip
Posted 1 day ago
Drury Inn & Suites Sikeston, MO
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

10/10 Excellent
"Dianna, the host, is so nice. She communicated very well, and she went above and beyond to make our stay as smooth as it could be. Our check-in was very straightforward. We stayed there for a night to rest on our way to TN, and we will for sure do it again."
sofyan 1-night trip
Posted 2 days ago
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"We had no problem checking in. The room was nice and clean. The staff were courteous and helpful. Parking was acceptable. Close to our room. No complaints."
Carol 2-night trip
Posted 3 days ago
Super 8 by Wyndham Sikeston/Miner Area
Drury Inn Paducah

Drury Inn Paducah

10/10 Excellent
"Very nice, clean and staff were helpful. Within walking distance to Hancock fabric store."
Frances 2-night trip
Posted 4 days ago
Drury Inn Paducah
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 4 days ago
The Riverstone Hotel Charleston-Sikeston

Other attractions near Fort Defiance State Park

Columbus-Belmont State Park

7.4/10 (23 reviews)
You can learn about the history of Columbus with a stop at Columbus-Belmont State Park.
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Ullin City Hall

6.6/10 (4 reviews)
After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums.
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Limekin Springs Trail Trailhead

You can take time to visit Limekin Springs Trail Trailhead during your travels to Ullin. Make some time to visit the shops while you're in the area.
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Front Street Studio & Art Gallery

8.6/10 (15 reviews)
You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this relaxing area, you can savor the top-notch restaurants.
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Lower Cache River Access Area

You can take time to visit Lower Cache River Access Area during your travels to Cypress.
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City of Miner Convention Center

Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants.
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Henry N Barkhausen Cache River Wetlands Center

8.0/10 (1 review)
You can spend time studying the exhibits at Henry N Barkhausen Cache River Wetlands Center during your travels in Cypress. Amble around the area's parks or experience its museums.
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Frequently asked questions

What are the top-rated hotels near Fort Defiance State Park?
Discovering the perfect stay near Fort Defiance State Park can enhance any traveler's experience, especially with top-rated hotels in Cairo, Illinois that cater to comfort and convenience.Quality Inn Cairo I-57Quality Inn Cairo I-57 offers a comfortable retreat just 5.0 miles from Fort Defiance State Park, making it an ideal choice for those exploring the area. Rated 6.6 by travelers, this hotel provides essential amenities such as free daily breakfast and air conditioning for a pleasant stay. Guests can take advantage of the in-room kitchen, complete with a refrigerator and microwave, perfect for preparing meals. The hotel also features free parking for RVs and trucks, ensuring convenient access for all travelers.
How much is a hotel near Fort Defiance State Park?
Staying near Fort Defiance State Park is a treat, with plenty of hotels from $65 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Fort Defiance State Park?
For families seeking a memorable stay near Fort Defiance State Park, here are some top-rated options that cater to all your needs.Quality Inn Cairo I-57Quality Inn Cairo I-57 is a family-friendly hotel located just 5.0 miles from Fort Defiance State Park. With a review rating of 6.6, this hotel provides essential amenities for families, including free cribs and a fully equipped kitchen. Guests can enjoy a complimentary full breakfast daily, making mornings straightforward. Additional amenities include free parking and air-conditioned rooms, ensuring a comfortable stay for everyone.
What are the best affordable hotels near Fort Defiance State Park?
For travelers seeking affordable and family-friendly hotels near Fort Defiance State Park, these options deliver comfort without breaking the bank.Quality Inn Cairo I-57Quality Inn Cairo I-57 is a convenient choice located just 5.0 miles from Fort Defiance State Park, a review rating of 6.6. This hotel offers family-friendly amenities such as free cribs and breakfast options to make traveling with children easier. Guests can enjoy complimentary WiFi, air conditioning, and access to a microwave and refrigerator in the rooms, ensuring a comfortable stay for families. With free self-parking and daily housekeeping, this hotel combines affordability and essential conveniences for a pleasant getaway.
What are the best pet-friendly hotels near Fort Defiance State Park?
Finding a pet-friendly hotel near Fort Defiance State Park can enhance your outdoor adventure with your furry friend. Here are top-rated options that cater to both comfort and convenience for you and your pet.Quality Inn Cairo I-57Quality Inn Cairo I-57 is just 5.0 miles from Fort Defiance State Park and has a welcoming atmosphere for travelers with pets. This 2-star hotel allows pets, ensuring a pleasant stay for both travelers and their furry companions. With a review rating of 6.6, it features convenient amenities like free breakfast, air conditioning, and in-room kitchen facilities, including a refrigerator and microwave. The hotel also provides free parking and early check-in, making it a practical choice for families and pet owners.
Can I book a fully refundable hotel close to Fort Defiance State Park?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Fort Defiance State Park", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

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