Default HTG hotel image

Find hotels near Fort Defiance State Park, Cairo from $66

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 9 - Sep 10
Tomorrow
Sep 10 - Sep 11
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Filter by

Star rating

Guest rating

Our top choices for Fort Defiance State Park hotels

A large hotel with a prominent sign reading "Harriss" and a decorative archway with lights.
A lobby with leather seating, a reception desk, and a patterned carpet.
A casino bar with multiple gaming machines, a central bar area with stools, and a patterned carpet.
A modern bar area with a long counter, bar stools, and a wooden ceiling.

1. Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
25.2 mi from Fort Defiance State Park
United States
Jason
$115 nightly
$128 total
Sep 10 - Sep 11
Total with taxes and fees
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
A hotel lobby with a reception desk, seating area, and a large window.
A hotel room with a desk, chair, television, and a lamp.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

2. Quality Inn Cairo I-57

Quality Inn Cairo I-57
4.8 mi from Fort Defiance State Park
United States
Susan
$70 nightly
$78 total
Oct 2 - Oct 3
Total with taxes and fees
Quality Inn Cairo I-57
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.

3. The Riverview

The Riverview
30.6 mi from Fort Defiance State Park
United States
Alyssa
$110 nightly
$125 total
Sep 14 - Sep 15
Total with taxes and fees
The Riverview
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A spacious living room with a sofa set, a coffee table, and a dining area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

4. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
30.5 mi from Fort Defiance State Park
United States
Kristin
$125 nightly
$142 total
Sep 20 - Sep 21
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
22.6 mi from Fort Defiance State Park
United States
Scott Andrew
$94 nightly
$108 total
Sep 14 - Sep 15
Total with taxes and fees
Drury Inn & Suites Sikeston, MO
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

6. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
26.1 mi from Fort Defiance State Park
United States
Allen
$101 nightly
$114 total
Sep 17 - Sep 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

7. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
26.1 mi from Fort Defiance State Park
United States
Lauren
$118 nightly
$134 total
Sep 17 - Sep 18
Total with taxes and fees
TownePlace Suites by Marriott Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A buffet with various food items, including omelets and baked goods, served in metal containers.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
25.7 mi from Fort Defiance State Park
United States
Melissa
$106 nightly
$120 total
Oct 9 - Oct 10
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

9. Hampton Inn Sikeston

Hampton Inn Sikeston
26 mi from Fort Defiance State Park
United States
Jeffrey
$103 nightly
$116 total
Sep 13 - Sep 14
Total with taxes and fees
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

10. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
22.3 mi from Fort Defiance State Park
United States
Bernice
$87 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

11. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
22.6 mi from Fort Defiance State Park
United States
Sharika West
$53 nightly
$60 total
Sep 10 - Sep 11
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.
A living room with two sofas, a coffee table, a TV, and a cabinet.

12. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
22.6 mi from Fort Defiance State Park
United States
Lakeysha
$89 nightly
$101 total
Oct 4 - Oct 5
Total with taxes and fees
Comfort Inn & Suites Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

13. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
22.4 mi from Fort Defiance State Park
United States
Val
$66 nightly
$76 total
Sep 13 - Sep 14
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

14. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
22.8 mi from Fort Defiance State Park
United States
Kevin
$57 nightly
$65 total
Sep 16 - Sep 17
Total with taxes and fees
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
A reception desk with a computer, a framed picture on the wall, and a vase with flowers.
A motel with a red roof and beige walls, a parking lot, and a signboard.
A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.

15. La Center Motel

La Center Motel
10.9 mi from Fort Defiance State Park
United States
Carrie
$65 nightly
$70 total
Sep 20 - Sep 21
Total with taxes and fees
La Center Motel
A building with a fountain and flower beds in front.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

16. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
12.6 mi from Fort Defiance State Park
United States
Jay
$66 nightly
$73 total
Sep 19 - Sep 20
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

17. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
10.9 mi from Fort Defiance State Park
United States
France
$60 nightly
$66 total
Sep 10 - Sep 11
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

18. Eagle Inn Charleston

Eagle Inn Charleston
10 mi from Fort Defiance State Park
United States
Jackson
$77 nightly
$85 total
Sep 10 - Sep 11
Total with taxes and fees
Eagle Inn Charleston
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.
A bathroom with a bathtub, toilet, and shower curtain.

19. Country Yard Inn and Suite

Country Yard Inn and Suite
22.3 mi from Fort Defiance State Park
United States
William
$56 nightly
$63 total
Oct 9 - Oct 10
Total with taxes and fees
Country Yard Inn and Suite
An indoor swimming pool with wooden walls and stone accents, surrounded by seating areas and a balcony.
A conference room with a stage, chairs, and a carpeted floor.
A gym with treadmills, ellipticals, and a stationary bike.
A hotel room with a large bed, a chair, a desk, a desk lamp, a lamp, a window with curtains, a picture on the wall, and a bathroom with a bathtub and a mirror.

20. Baymont by Wyndham Metropolis

Baymont by Wyndham Metropolis
25.3 mi from Fort Defiance State Park
United States
Julee
Baymont by Wyndham Metropolis
View all properties

Compare popular hotels close to Fort Defiance State Park

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
La Center Motel
7.6
Good
22 reviews
View
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
Super 8 by Wyndham Charleston/Sikeston East MO
6.8
665 reviews
View
A building with a fountain and flower beds in front.
The Riverstone Hotel Charleston-Sikeston
6.8
431 reviews
View
A hotel lobby with a reception desk, seating area, and a large window.
Quality Inn Cairo I-57
6.4
294 reviews
View
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
Eagle Inn Charleston
6.6
107 reviews
View

Top Fort Defiance State Park Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

8/10 Good
"The sheets in the bed had a blood stain on it. I told the lady at the front desk and she came and changed the sheets for me. The stopper in the sink for the bathroom was not functional. The couch in the office area had stains on it. The refrigerator freezer needed to be defrosted. It had a lot of built up ice. Other than that, the room was acceptable. The staff was very helpful."
James 2-night trip
Posted 6 hours ago
Days Inn and Suites by Wyndham Sikeston
La Quinta Inn & Suites by Wyndham Paducah

La Quinta Inn & Suites by Wyndham Paducah

10/10 Excellent
"Awesome staff, Room was spotless, The hot tub was out of order."
Jeff 1-night trip
Posted 9 hours ago
La Quinta Inn & Suites by Wyndham Paducah
Drury Inn & Suites Paducah

Drury Inn & Suites Paducah

10/10 Excellent
"Staff was excellent, breakfast was very good and Happy Hour was a hit as well!"
Michael 1-night trip
Posted 11 hours ago
Drury Inn & Suites Paducah
Drury Inn Paducah

Drury Inn Paducah

10/10 Excellent
"Very nice, clean and staff were helpful. Within walking distance to Hancock fabric store."
Frances 2-night trip
Posted 1 day ago
Drury Inn Paducah
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 2 days ago
The Riverstone Hotel Charleston-Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

8/10 Good
"Great location, nice, clean and well maintained, Hotel employees were very helpful great customer service,"
Bernice 2-night trip
Posted 2 days ago
Best Western Plus Sikeston I-55
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This was my second time staying at Drury hotel. I will most definitely book another stay."
Nicole 2-night trip
Posted 3 days ago
Drury Inn & Suites Sikeston, MO
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

10/10 Excellent
"Super nice host, house is clean and the area is so peaceful. I have so enjoyed my stay here."
Anonymous traveler 10-night trip
Posted 3 days ago
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"For a older hotel. It was pleasant. Very good staff"
Mark 2-night trip
Posted 5 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Other attractions near Fort Defiance State Park

Columbus-Belmont State Park

7.4/10 (23 reviews)
You can learn about the history of Columbus with a stop at Columbus-Belmont State Park.
See properties

Ullin City Hall

6.6/10 (4 reviews)
After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums.
See properties

Limekin Springs Trail Trailhead

You can take time to visit Limekin Springs Trail Trailhead during your travels to Ullin. Make some time to visit the shops while you're in the area.
See properties

Front Street Studio & Art Gallery

8.6/10 (15 reviews)
You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this relaxing area, you can savor the top-notch restaurants.
See properties

Lower Cache River Access Area

You can take time to visit Lower Cache River Access Area during your travels to Cypress.
See properties

City of Miner Convention Center

Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants.
See properties

Henry N Barkhausen Cache River Wetlands Center

8.0/10 (1 review)
You can spend time studying the exhibits at Henry N Barkhausen Cache River Wetlands Center during your travels in Cypress. Amble around the area's parks or experience its museums.
See properties

Frequently asked questions

What are the top-rated hotels near Fort Defiance State Park?
Discovering the perfect stay near Fort Defiance State Park can enhance any traveler's experience, especially with top-rated hotels in Cairo, Illinois that cater to comfort and convenience.Quality Inn Cairo I-57Quality Inn Cairo I-57 offers a comfortable retreat just 5.0 miles from Fort Defiance State Park, making it an ideal choice for those exploring the area. Rated 6.6 by travelers, this hotel provides essential amenities such as free daily breakfast and air conditioning for a pleasant stay. Guests can take advantage of the in-room kitchen, complete with a refrigerator and microwave, perfect for preparing meals. The hotel also features free parking for RVs and trucks, ensuring convenient access for all travelers.
How much is a hotel near Fort Defiance State Park?
Staying near Fort Defiance State Park is a treat, with plenty of hotels from $66 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Fort Defiance State Park?
For families seeking a memorable stay near Fort Defiance State Park, here are some top-rated options that cater to all your needs.Quality Inn Cairo I-57Quality Inn Cairo I-57 is a family-friendly hotel located just 5.0 miles from Fort Defiance State Park. With a review rating of 6.6, this hotel provides essential amenities for families, including free cribs and a fully equipped kitchen. Guests can enjoy a complimentary full breakfast daily, making mornings straightforward. Additional amenities include free parking and air-conditioned rooms, ensuring a comfortable stay for everyone.
What are the best affordable hotels near Fort Defiance State Park?
For travelers seeking affordable and family-friendly hotels near Fort Defiance State Park, these options deliver comfort without breaking the bank.Quality Inn Cairo I-57Quality Inn Cairo I-57 is a convenient choice located just 5.0 miles from Fort Defiance State Park, a review rating of 6.6. This hotel offers family-friendly amenities such as free cribs and breakfast options to make traveling with children easier. Guests can enjoy complimentary WiFi, air conditioning, and access to a microwave and refrigerator in the rooms, ensuring a comfortable stay for families. With free self-parking and daily housekeeping, this hotel combines affordability and essential conveniences for a pleasant getaway.
What are the best pet-friendly hotels near Fort Defiance State Park?
Finding a pet-friendly hotel near Fort Defiance State Park can enhance your outdoor adventure with your furry friend. Here are top-rated options that cater to both comfort and convenience for you and your pet.Quality Inn Cairo I-57Quality Inn Cairo I-57 is just 5.0 miles from Fort Defiance State Park and has a welcoming atmosphere for travelers with pets. This 2-star hotel allows pets, ensuring a pleasant stay for both travelers and their furry companions. With a review rating of 6.6, it features convenient amenities like free breakfast, air conditioning, and in-room kitchen facilities, including a refrigerator and microwave. The hotel also provides free parking and early check-in, making it a practical choice for families and pet owners.
Can I book a fully refundable hotel close to Fort Defiance State Park?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Fort Defiance State Park", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

Explore a world of travel with Expedia