A swampy forest with tall trees and water reflecting sunlight.

Calhoun County Vacations & Trips from $322

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Your Calhoun County Vacation

Leave the planning to us with a Calhoun County vacation package. With everything organized before you go, all you'll have to do is sit back, relax and experience this destination's culture and beauty. Not sure where to stay first? Saint Matthews is among the most popular cities to visit during a trip to Calhoun County. From the moment you book your Calhoun County vacation to when you return home, Expedia has your back each step of the way.

Top destinations in Calhoun County

A swamp with tall trees and water reflecting the greenery.
FlightsHotels

Saint Matthews

Saint Matthews

The Latest Calhoun County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.
    Jan 26 - Jan 29

    Sleep Inn Columbia + Flight

    Seven Oaks
    3 nights
    2.5 star property
    8.2/10 - Very good (1,224 reviews)
    "clean room nice staff"
    Reviewed November 12, 2026
    Roundtrip • Boston (BOS) - Columbia (CAE)
    BOS - MYR • 1 stop MYR - BOS • 1 stop
    $366
    $322
    per traveler
    found 2 hours ago
    Sleep Inn Columbia
  • An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.
    Jan 26 - Jan 29

    Hyatt Place Columbia/Downtown/The Vista + Flight

    Downtown Columbia
    3 nights
    3.0 star property
    8.6/10 - Excellent (1,010 reviews)
    "Great!"
    Reviewed November 13, 2026
    Roundtrip • Boston (BOS) - Columbia (CAE)
    BOS - MYR • 1 stop MYR - BOS • 1 stop
    $503
    $408
    per traveler
    found 2 hours ago
    Hyatt Place Columbia/Downtown/The Vista
  • A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.
    Jan 26 - Jan 29

    The Lantern Hotel Columbia + Flight

    Downtown Columbia
    3 nights
    4.0 star property
    9.8/10 - Exceptional (234 reviews)
    Roundtrip • Boston (BOS) - Columbia (CAE)
    BOS - MYR • 1 stop MYR - BOS • 1 stop
    $563
    $474
    per traveler
    found 2 hours ago
    The Lantern Hotel Columbia
  • A spacious indoor area with wooden flooring, multiple seating arrangements including tables and chairs, and large windows providing natural light.
    Jan 26 - Jan 29

    Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG + Flight

    Downtown Columbia
    3 nights
    2.5 star property
    8.8/10 - Excellent (808 reviews)
    Roundtrip • Boston (BOS) - Columbia (CAE)
    BOS - MYR • 1 stop MYR - BOS • 1 stop
    $469
    $406
    per traveler
    found 2 hours ago
    Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG
  • A modern restaurant with high tables and chairs, a bar area, and a visible kitchen in the background.
    Dec 25 - Dec 28

    Garner Hotel Sumter Northwest by IHG + Flight

    Sumter
    3 nights
    2.5 star property
    6.4/10 - (621 reviews)
    "The shower was not properly cleaned. Stull had hair from the previous guest."
    Reviewed November 1, 2026
    Roundtrip • New York (NYC) - Columbia (CAE)
    LGA - CAE • Nonstop CAE - LGA • Nonstop
    $608
    $545
    per traveler
    found 1 day ago
    Garner Hotel Sumter Northwest by IHG

What to do in Calhoun County

Congaree National Park Self Guided Audio Walking Tour

Congaree National Park Self Guided Audio Walking Tour

$13
per traveler
0% of travelers recommend
Congaree National Park Self Guided Audio Walking Tour
See all activities in Calhoun County
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.