Castro District Vacations from $263

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Castro District Vacation

Discover all the amazing things this neighborhood has to offer with a customized Castro District vacation package. However you imagine spending your time here, you'll find endless opportunities for fun, adventure and relaxation. Wondering where to go during your trip to Castro District? Nearby attractions like Lombard Street, Palace of Fine Arts and University of San Francisco are great places to start. Whatever your travel goals or the size of your budget, booking a perfect Castro District vacation is a cinch with Expedia.

The Latest Castro District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Mosser

The Mosser

3 out of 5
Downtown San Francisco
Price was $394, price is now $263 per person
$263
per person
Feb 13 - Feb 15
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
8/10 Very Good! (1,002 reviews)
Staffs are great, room is clean, but there’s no fridge.

Reviewed on Dec 20, 2025

Montage Healdsburg

Montage Healdsburg

5 out of 5
Save 100% on your flight
Price was $2,069, price is now $1,165 per person
$1,165
per person
Feb 12 - Feb 15
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.6/10 Exceptional! (113 reviews)
Clean room, kind and helpful staff. Nice ambiance in vineyard.

Reviewed on Nov 30, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,540, price is now $1,026 per person
$1,026
per person
Mar 4 - Mar 7
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (486 reviews)
The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive.

Reviewed on Dec 7, 2025

Inn At The Opera

Inn At The Opera

3.5 out of 5
Fillmore District
Save 100% on your flight
Price was $456, price is now $308 per person
$308
per person
Feb 26 - Feb 28
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
8.4/10 Very Good! (700 reviews)
Our room was hot and stuffy so we had to open the window which let in the noise from the outside. The hotel is located a couple blocks from the shops and restaurants at Hayes Valley which was nice. It was very walkable from the BART civic center station.

Reviewed on Aug 12, 2025

Union Square Plaza Hotel

Union Square Plaza Hotel

2 out of 5
Union Square
Save 100% on your flight
Price was $591, price is now $407 per person
$407
per person
Feb 6 - Feb 8
found 19 hours ago
Roundtrip flight included
Los Angeles (QLA) to San Francisco (SFO)
7.2/10 Good! (1,000 reviews)
Very convenient for one night out in the center of San Francisco.

Reviewed on Nov 28, 2025

Where to stay in Castro District

Find the best Castro District areas and neighborhoods for the activities you enjoy most. Learn more about Castro District
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Castro District Hotel Deals

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $168 total per night from Dec 22 to Dec 23
$168 total
Dec 22 - Dec 23
Total with taxes and fees
8.8/10 Excellent! (7,187 reviews)
Very clean hotel & staff were very polite

Reviewed on Dec 17, 2025

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
$112 nightly
The price is $132 total per night from Dec 23 to Dec 24
$132 total
Dec 23 - Dec 24
Total with taxes and fees
8.6/10 Excellent! (2,151 reviews)
Great hotel

Reviewed on Dec 16, 2025

Hilton San Francisco Financial District
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
$251 nightly
The price is $295 total per night from Jan 4 to Jan 5
$295 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9/10 Wonderful! (1,427 reviews)
Very good hotel. Love it

Reviewed on Dec 17, 2025

Fairmont San Francisco
See all 4,788 properties in Castro District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Castro District

Mission Dolores Park showing picnicing and a park as well as a small group of people

Mission Dolores Park

Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.

Mission Dolores Park
Mission San Francisco de Asís was founded 29 June 1776 by Padre Francisco Palóu and Padre Pedro Benito Cambón. The mission is named for Saint Francis of Assisi. The current site was picked in 1782 because of the harsh conditions at the original mission. It is considered to be the oldest intact building in San Francisco. The Mission is located in the San Francisco Mission District at the corner of 16th and Dolores Streets. #Details #golden #troveontuesday #Trovember

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area.

Mission San Francisco de Asís

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
Visit de Young Museum in Golden Gate Park

de Young Museum General Admission Ticket

$20
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.