Central Macedonia Vacations & Trips from $1,180

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Central Macedonia Vacation

When adventure calls, answer it with a tailor-made vacation package to Central Macedonia. Wherever your travels lead and whatever your plans are, get set to discover a destination with so much to offer. With so many things to see on a trip to Central Macedonia, it can be hard to know where to start. Kick off your travels in Thessaloniki at White Tower of Thessaloniki and Tsimiski Street — two popular attractions here. Another top city to add to your itinerary is Kassandra. Don't miss Kalithea Beach and Siviri Beach. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next dream Central Macedonia vacation.

Top destinations in Central Macedonia

A waterfront cityscape with modern buildings, a calm sea, and a clear blue sky.

Thessaloniki

Thessaloniki
A beach at sunset with umbrellas and lounge chairs.

Katerini

Katerini
A coastal town with white buildings, a sandy beach, and a hilly background.

Kassandra

Kassandra
A beach chair and table facing a sunset over water.

Sithonia

Sithonia
A coastal beach with clear turquoise waters, rocky cliffs, and sparse vegetation.

Nea Propontida

Nea Propontida
A mountain range with a prominent peak and a valley.

Dio-Olympos

Dio-Olympos
A coastal cityscape at dusk with a prominent waterfront, dense urban buildings, and a historic fortress.

Thermi

Thermi

The Latest Central Macedonia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
September Hotel Thessaloniki

September Hotel Thessaloniki

$1,180
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Thessaloniki (SKG)
9.4/10 Exceptional! (95 reviews)
The Met Hotel, a member of Design Hotels

The Met Hotel, a member of Design Hotels

$1,267
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Thessaloniki (SKG)
9.2/10 Wonderful! (913 reviews)
Beautiful large reception. Nice dining choices. Nice transportation in to the city center

Reviewed on Sep 23, 2026

ONOMA Hotel

ONOMA Hotel

Vardaris
$1,184
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Thessaloniki (SKG)
9.4/10 Exceptional! (186 reviews)
Daios Luxury Living

Daios Luxury Living

Thessaloniki City Centre
$1,468
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Thessaloniki (SKG)
9.6/10 Exceptional! (807 reviews)
MonAsty, Thessaloniki, Autograph Collection

MonAsty, Thessaloniki, Autograph Collection

Thessaloniki City Centre
$1,277
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Thessaloniki (SKG)
9.8/10 Exceptional! (197 reviews)
Good position, well laid out room, nice staff. Only weakness were the two, small and unconnected lifts.

Reviewed on Sep 23, 2026

Where to stay in Central Macedonia

Find the best Central Macedonia areas and neighborhoods for the activities you enjoy most.
A festive square with a large illuminated Christmas tree, surrounded by buildings with illuminated facades.
A collection of transparent umbrellas against a clear blue sky.
Photo by Johnny Voulgarakis
A historic stone tower with a flag on top, surrounded by trees and people in a public square.
Photo by Alisa Otchertsova
A historic stone tower with a flag, surrounded by trees and people in a park.
Photo by Alisa Otchertsova
A historic building with a round tower and a tall chimney.

Thessaloniki City Centre

If you're spending time in Thessaloniki City Centre, check out sights like Tsimiski Street or Nikis Avenue and hop on the metro to see more the city at Agias Sofias Metro Station or Venizelou Metro Station.

A cobblestone street lined with shops and buildings adorned with string lights.

Ladadika

Ladadika is known for its ample dining options, and you can make a stop by Nikis Avenue and Place Katouni while in the area.

A historic building with arched windows and a tower.
An ancient brick archway with stone bases, surrounded by modern buildings.
Ancient stone arches with intricate carvings, set against a backdrop of modern buildings and a clear blue sky.
A large stone archway with intricate carvings, surrounded by modern buildings and a clear sky.
A detailed stone monument with carvings of historical figures and scenes, set against a modern urban backdrop.
Photo by Lara Dunning

Kamara

If you're spending some time in Kamara, Ataturk Museum and Church of Saint Demetrius are top sights worth seeing.

A coastal cityscape with a prominent castle, modern buildings, and a park with trees.
A hillside with terraced gardens, a stone bridge, and a view of a coastal cityscape.
Photo by Sofia Mis

Old Town Thessaloniki

Travelers like the historic sites in Old Town Thessaloniki, and Church of Hosios David is a top attraction you might want to visit.

A cityscape with a prominent church, a mountain, and a dense forested area.

Vardaris

Vardaris is positively reviewed for its shopping, bars, and spas, and you can quickly pop around to sights in the larger Thessaloniki area at New Railway Station Metro Station or Dimokratias Metro Station.

Find the Best Central Macedonia Vacation Packages

Central Macedonia Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Closest Airport
Macedonia Airport (SKG)
Top Sights
Nikiti Beach, Kalithea Beach and Olympic Beach

Central Macedonia Hotel Deals

NYX Hotel Thessaloniki

NYX Hotel Thessaloniki

1 Tsimiski Thessaloniki
Fully refundableReserve now, pay when you stay
$128 nightly
$157 total
Oct 26 - Oct 27
Total with taxes and fees
9.4/10 Exceptional! (100 reviews)
"Great location. Right in the center of town and walking distance from the old harbor, Aristotle square, food and shopping. Rooms are small but well equipped. A bit tight for a couple with luggage but manageable. Nice breakfast. No parking. Hotel offers valet parking for 30 EUR per night which is ..."

Reviewed on Sep 22, 2026

NYX Hotel Thessaloniki
City Hotel Thessaloniki

City Hotel Thessaloniki

11 Komninon Street Thessaloniki Central Macedonia
$106 nightly
$132 total
Oct 18 - Oct 19
Total with taxes and fees
8.6/10 Excellent! (682 reviews)
"fabulous location, you can walk to everything. refreshingly clean & quiet; also a comfortable bed. i was grateful that the staff hauled all my luggage, they had a map and the front desk person explained everything and where to go and what to see. there were enough towels & shower supplies as ..."

Reviewed on Sep 18, 2026

City Hotel Thessaloniki
The Met Hotel, a member of Design Hotels

The Met Hotel, a member of Design Hotels

48, 26th October Street Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
$174 nightly
$215 total
Oct 25 - Oct 26
Total with taxes and fees
9.2/10 Wonderful! (919 reviews)
"Beautiful large reception. Nice dining choices. Nice transportation in to the city center"

Reviewed on Sep 23, 2026

The Met Hotel, a member of Design Hotels
See all 4,436 properties in Central Macedonia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations
Golf Vacations
Golf Vacations
Luxury Vacations
Luxury Vacations
Romantic Vacations
Romantic Vacations
Ski Vacations
Ski Vacations
Gay Friendly Vacations
LGBTQ Friendly Vacations
LGBTQ Friendly Vacations
Adventure Vacations
Adventure Vacations
Vacations in Month
Where to go when
Where to go when
Honeymoon Vacations
Honeymoon Vacations
Mountain Vacations
Mountain Vacations
Fishing Vacations
Fishing Vacations
Adults Only Vacations
Adults Only Vacations
Waterpark Vacations
Waterpark Vacations
Scuba Diving Vacations
Scuba Diving Vacations
Yoga Vacations
Yoga Vacations
Cheap Vacations
Cheap Vacations
Solo Vacations
Solo Vacations

Stay near popular Central Macedonia attractions

A coastal cityscape with a large public square, waterfront buildings, and a view of the sea.

Aristotelous Square

9.2/10 (1,097 reviews)
Visit Thessaloniki’s main square, a busy gathering place for locals and the site of major events throughout the year.
See properties
An ancient stone structure with a statue in the center, surrounded by greenery.
Photo by Tony Tsap

Mount Olympus

9.6/10 (63 reviews)
Commune with nature and explore the great outdoors at Mount Olympus during your travels in Dio-Olympos. Amble around the area's seaside or visit its spas.
See properties
A seaside patio with tables and chairs, a barbecue area, and umbrellas overlooking the ocean.
Photo by Ivan

Kalithea Beach

8.2/10 (81 reviews)
Why not spend a carefree afternoon at Kalithea Beach during your travels in Kallithea? Stroll along the area's seaside or simply enjoy its restaurants.
See properties
A historic tower with a circular base and a dome, surrounded by a park with trees and people.

White Tower of Thessaloniki

9.2/10 (1,132 reviews)
This distinctly shaped tower has evolved alongside Thessaloniki over the centuries and now houses a museum dedicated to the city’s history.
See properties
A city street at night with illuminated snowflake decorations and trees.

Tsimiski Street

9.2/10 (347 reviews)
You can enjoy retail therapy at Tsimiski Street during your trip to Thessaloniki.
See properties

Nikiti Beach

8.4/10 (103 reviews)
Why not spend a carefree afternoon at Nikiti Beach during your travels in Nikiti? Wander the marina or discover the area's mountain views.
See properties

Kalogria Beach

8.8/10 (56 reviews)
If a restful vacation is part of your travel plans, Kalogria Beach might be the perfect place to seek out during your trip to Sithonia. While you're in the area, stroll along the marina.
See properties

Leptokarya Beach

7.6/10 (26 reviews)
Why not spend a carefree afternoon at Leptokarya Beach during your travels in Dio-Olympos? Stroll along the seaside or visit the spas in the area.
See properties

What to do in Central Macedonia

Thessaloniki: Vergina and Pella Day Trip

Thessaloniki: Vergina and Pella Day Trip

$57
per adult
90% of travellers recommend
Thessaloniki: Vergina and Pella Day Trip
Big Bus Thessaloniki Hop-on Hop-off Bus Tour with Audio Guide

Big Bus Thessaloniki Hop-on Hop-off Bus Tour with Audio Guide

$20
per adult
Big Bus Thessaloniki Hop-on Hop-off Bus Tour with Audio Guide
Walking Talking Food

Walking Talking Food

$80
per adult
100% of travellers recommend
Walking Talking Food
See all activities in Central Macedonia
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.