Title: $291 Cheap Flights to Santiago do Cacém - Expedia.com

![A beautiful reminder of the Romans.  Very peaceful and quiet with a well preserved bathhouse and original Roman roads. ](https://images.trvl-media.com/place/182251/b11a7905-519c-4cba-af4d-ff7132a823b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Kate Parker

![](https://images.trvl-media.com/place/182251/b11a7905-519c-4cba-af4d-ff7132a823b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# $291 Cheap Flights to Santiago do Cacém

[View $291 flight on Sun, Mar 22, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:JFK,to:LIS,departure:3/22/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:291.00&airProductToken=AQpfCiwI1bABEgI5MhipUSCMGCi5rYgDMOKwiAM4QUAAWAFqBExJVEVyBkFZWU8yTAovCNWwARIEMTE1ORiMGCCLkgEo6rmIAzC6uogDOEFAAVgBagRMSVRFcgZBWVlPMkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) 

[Santiago do Cacém Travel Guide](https://expedia.com/Santiago-Do-Cacem.dx182251)[Hotels in Santiago do Cacém](https://expedia.com/Santiago-Do-Cacem-Hotels.d182251.Travel-Guide-Hotels)[Things to do in Santiago do Cacém](https://expedia.com/Things-To-Do-In-Santiago-Do-Cacem.d182251.Travel-Guide-Activities)[Car Rentals in Santiago do Cacém](https://expedia.com/Car-Rentals-In-Santiago-Do-Cacem.d182251.Car-Rental-Guide)[Santiago do Cacém Vacation Packages](https://expedia.com/Santiago-Do-Cacem.d182251.Destination-Travel-Guides)

## Popular airlines to Santiago do Cacém

- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg)  
TAP Portugal  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg)  
Lufthansa  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg)  
British Airways  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LX.svg)  
Swiss International Air Lines  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LX"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg)  
Iberia  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg)  
KLM  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}])
- ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg)  
Air France  
[](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago do Cacém, Setúbal District, Portugal,departure:3/29/2026TANYT&leg2=from:Santiago do Cacém, Setúbal District, Portugal,to:CMH,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}])

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## How much is the cheapest flight to Santiago do Cacém?

Prices were available within the past 7 days and start at $291 for one-way flights and $441 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif)

Sun, Nov 15 - Sat, Nov 21

BOS

Boston

LIS

Lisbon

$441

Roundtrip

found 1 hour ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOS,to:LIS,departure:11/15/2026TANYT&leg2=from:LIS,to:BOS,departure:11/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:440.73&airProductToken=AQo2CjQI1KABEgMyMTYYwZMBIIuSASj-op0DMImmnQM4VEAAWAFqB0RJU0NJTlRyCFRMMERTSTgwCncKQAjUoAESBDE5MzQYi5IBIO5zKJjinQMw1OKdAzhUQABYAWoHRElTQ0lOVHIIVEwwRFNJODB6CgjOkgESBDE5MzQKMwjUoAESAzIyNxjucyDBkwEouO2dAzCJ8Z0DOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0)

![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif)

Fri, Nov 13 - Fri, Nov 20

JFK

New York

LIS

Lisbon

$465

Roundtrip

just found

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:JFK,to:LIS,departure:11/13/2026TANYT&leg2=from:LIS,to:JFK,departure:11/20/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:464.23&airProductToken=AQpfCiwI1bABEgI5MhipUSCMGCi5jJ0DMOKPnQM4WkAAWAFqBExJVEVyBlpMWVI3TAovCNWwARIEMTE1NRiMGCCLkgEow5GdAzCTkp0DOFpAAVgBagRMSVRFcgZaTFlSN0wKXwovCNWwARIEMTE1MBiLkgEgjBgo99OdAzDC1J0DOFpAAFgBagRMSVRFcgZaTFlSN0wKLAjVsAESAjkxGIwYIKlRKKvVnQMwmtmdAzhaQAFYAWoETElURXIGWkxZUjdMEgwIARABGAEqAlVYMgAYASIECAEQASgCKAMoBDAB)

![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif)

Tue, Apr 14 - Tue, Apr 21

BOS

Boston

LIS

Lisbon

$481

Roundtrip

just found

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOS,to:LIS,departure:4/14/2026TANYT&leg2=from:LIS,to:BOS,departure:4/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:480.63&airProductToken=AQpnCjEI05YBEgM5MjgYwZMBIOI7KNStigMwjLGKAzhMQABYAWoFTElHSFRyCExMWEE2R0hUCjII05YBEgQyODAxGOI7IIuSASjgs4oDMMu1igM4TEABWAFqBUxJR0hUcghMTFhBNkdIVApnCjII05YBEgQyODAyGIuSASDiOyjg-YoDMK37igM4VEAAWAFqBUxJR0hUcghUTFhBNkdIVAoxCNOWARIDOTI3GOI7IMGTASjtgosDMNeGiwM4VEABWAFqBUxJR0hUcghUTFhBNkdIVBIKCAEQARgBKgJTSxgBIgQIARABKAIoAygEMAE)

![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif)

Wed, Nov 25 - Wed, Dec 2

BOS

Boston

FAO

Algarve

$515

Roundtrip

found 9 hours ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOS,to:FAO,departure:11/25/2026TANYT&leg2=from:FAO,to:BOS,departure:12/2/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:514.03&airProductToken=AQptCjUI1YIBEgQ4ODUyGMGTASClBCjlkJ4DMJOUngM4S0AAWAFqCEVDT0JBU0lDcghLTFg3NllCUQo0CNWCARIEOTI1NhilBCCFcCi1lp4DMPOXngM4S0ABWAFqCEVDT0JBU0lDcghLTFg3NllCUQprCjQIzLABEgQ4MjY5GIVwILk8KLDcngMw1d2eAzhMQABYAWoIRUNPTElHSFRyCExMWDc2QUJRCjMIzLABEgI1Mhi5PCDBkwEovuieAzDQ7J4DOExAAVgBaghFQ09MSUdIVHIITExYNzZBQlESDAgBEAEYASoCVUEyABgBIgQIARABKAIoAygEMAE)

![Swiss International Air Lines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LX.gif)

Tue, Apr 14 - Tue, Apr 28

BOS

Boston

FAO

Algarve

$530

Roundtrip

found 5 hours ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOS,to:FAO,departure:4/14/2026TANYT&leg2=from:FAO,to:BOS,departure:4/28/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:529.06&airProductToken=AQpwCjAIzLABEgI1MxjBkwEguTwoxK-KAzD3sooDOExAAFgBagVFTFQwMHIITExYNzZBQlEKPAjMsAESBDgyNjgYuTwghXAoxrWKAzDwtooDOExAAFgBagVFTFQwMHIITExYNzZBQlF6CQjXlgESAzI2OApwCjwIzLABEgQ4MjY5GIVwILk8KL3JiwMw58qLAzhMQABYAWoFRUxUMDByCExMWDc2QUJRegkI15YBEgMyNjkKMAjMsAESAjUyGLk8IMGTASjH04sDMLvXiwM4TEAAWAFqBUVMVDAwcghMTFg3NkFCURIKCAEQARgBKgJMWBgBIgQIARABKAIoAygEMAs)

## Find the cheapest month to fly from Columbus (CMH) to Lisbon (LIS)

### January is typically the cheapest month to fly

From $491 - $1,049 per traveler.

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=FTG_SPRING_PROMO_)

## Frequently asked questions

### What month is the cheapest to fly to Santiago do Cacém?

### Which US cities fly direct to Santiago do Cacém?

> - Boston
> - Newark
> - Washington
> - New York
> - Miami

### How to find a cheap flight to Santiago do Cacém?

### How to get a cheap last-minute flight to Santiago do Cacém?

### How far in advance should I book a flight to Santiago do Cacém?

### Which day of the week is the cheapest day to buy a plane ticket to Santiago do Cacém?

### Which airlines fly to Santiago do Cacém?

> - TAP Portugal
> - Air France
> - British Airways
> - Iberia

### Where do you fly into Santiago do Cacém?

### How far is the airport from central Santiago do Cacém?

### Can I save money by booking a Santiago do Cacém trip package?

### Can I change or cancel my flight to Santiago do Cacém?

\*Flight schedules are subject to change.

## Book with confidence

# Tips to find the cheapest flights to Santiago do Cacém

**The cheapest day to fly**

Get started finding a cheap flight to Santiago do Cacém on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you.

**The cheapest month to fly**

November is the cheapest month to fly to Santiago do Cacém. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Santiago do Cacém. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute. 

**The most affordable time to book a flight**

Typically, a Sunday can be the cheapest time to book a flight to Santiago do Cacém, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation. 

**The cheapest round-trip tickets to Santiago do Cacém**

The lowest price for round-trip flights to Santiago do Cacém in 2026 starts from from $441, while one-way tickets start from from $291\. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Santiago do Cacém. If you have a preferred departure time or airline, you can use the handy filters to customize your search.

**The cheapest airlines flying to Santiago do Cacém**

Air Europa, TAP Portugal, SATA International-Azores Airlines S.A., Swiss International Air Lines, Lufthansa, Scandinavian Airlines, United are just some of the airlines that can typically offer cheap tickets to Santiago do Cacém. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Santiago do Cacém and countless more destinations worldwide.

**The most affordable airports to fly into**

To view the cheapest airports to fly into for Santiago do Cacém, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Santiago do Cacém. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia.

**Save with a package**

With Expedia's amazing [package deals](https://www.expedia.com/package-deals), you could save hundreds of dollars by booking your Santiago do Cacém plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving. 

**Date flexibility for the cheapest flights to Santiago do Cacém**

If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Santiago do Cacém. 

**Stopover savings**

The cheapest tickets to Santiago do Cacém are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Santiago do Cacém. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved.

**Get Expedia's Price Drop Protection**

Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference\*. This gives you peace of mind that you're getting one of the cheapest flights to Santiago do Cacém for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members.

\*Terms apply.

**Use our Price Tracking feature**

Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Santiago do Cacém. Simply download the free Expedia app to your smart device and activate Santiago do Cacém flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices.

**Book with Expedia**

As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Santiago do Cacém. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. 

## Travel information

| Destination airport           | Humberto Delgado |
| ----------------------------- | ---------------- |
| Destination airport IATA code | LIS              |
| Destination city name         | Lisbon           |
| Roundtrip price               | $441             |

## Trending flights to Santiago do Cacém

Prices were available within the past 7 days and start at $291 for one-way flights and $441 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif)

Sun, Nov 15 - Sat, Nov 21

BOS

Boston

LIS

Lisbon

$441

Roundtrip

found 1 hour ago

[](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOS,to:LIS,departure:11/15/2026TANYT&leg2=from:LIS,to:BOS,departure:11/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:440.73&airProductToken=AQo2CjQI1KABEgMyMTYYwZMBIIuSASj-op0DMImmnQM4VEAAWAFqB0RJU0NJTlRyCFRMMERTSTgwCncKQAjUoAESBDE5MzQYi5IBIO5zKJjinQMw1OKdAzhUQABYAWoHRElTQ0lOVHIIVEwwRFNJODB6CgjOkgESBDE5MzQKMwjUoAESAzIyNxjucyDBkwEouO2dAzCJ8Z0DOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0)

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