Title: $146 Cheap Flights to Santiago - Expedia.com ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $146 Cheap Flights to Santiago [View $146 flight on Sat, Jun 13, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:MIA,to:PTY,departure:6/13/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:145.75&airProductToken=AQoxCi8Iw5oBEgMzMzMYjAIg78QBKLrQjwMw9NGPAzhBQABYAWoDQkFTcghBTEE5T1oyUxIKCAEQARgBKgJDTRgBIgQIARABKAIoAygEMAs) [Santiago Travel Guide](https://expedia.com/Santiago.dx6191486)[Hotels in Santiago](https://expedia.com/Santiago-Hotels.d6191486.Travel-Guide-Hotels)[Car Rentals in Santiago](https://expedia.com/Car-Rentals-In-Santiago.d6191486.Car-Rental-Guide)[Santiago Vacation Packages](https://expedia.com/Santiago.d6191486.Destination-Travel-Guides) ## Popular airlines to Santiago - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AM"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Santiago, Veraguas, Panama,departure:4/16/2026TANYT&leg2=from:Santiago, Veraguas, Panama,to:CMH,departure:4/23/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) ## How much is the cheapest flight to Santiago? Prices were available within the past 7 days and start at $146 for one-way flights and $322 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Euroairlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/q4.gif) Wed, May 6 - Thu, May 21 BOC Bocas del Toro PAC Panama City $338 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOC,to:PAC,departure:5/6/2026TANYT&leg2=from:PAC,to:BOC,departure:5/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:337.90&airProductToken=AQonCiUI0WgSAzEwORjBEyCPECjOpIwDMI-ljAM4WUAAWAFyBVlGVFJUCicKJQjRaBIDMTA4GI8QIMETKNTMjQMwlc2NAzhZQABYAXIFWUZUUlQSDAgBEAEYASoCUTQyABgBIgQIARABKAIoAygEMAE) ![Euroairlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/q4.gif) Wed, May 6 - Thu, May 21 BOC Bocas del Toro PAC Panama City $365 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOC,to:PAC,departure:5/6/2026TANYT&leg2=from:PAC,to:BOC,departure:5/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:364.10&airProductToken=AQonCiUI0WgSAzEwORjBEyCPECjOpIwDMI-ljAM4WUAAWAFyBVlGVE9XEgwIARABGAEqAlE0MgAYASIECAEQASgCKAMoBDAB) ![Hahn Air Technologies](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/x1.gif) Wed, May 6 - Thu, May 21 BOC Bocas del Toro PAC Panama City $375 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOC,to:PAC,departure:5/6/2026TANYT&leg2=from:PAC,to:BOC,departure:5/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:374.10&airProductToken=AQonCiUI2GISAzIxNxjBEyCPECiboYwDMNehjAM4WUAAWAFyBVlSVDdQCicKJQjYYhIDMjI4GI8QIMETKMzNjQMwiM6NAzhZQABYAXIFWVJUN1ASDAgBEAEYASoCSFIyABgBIgQIARABKAIoAygEMAE) ![APG Distribution System](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/GP.gif) Wed, Apr 29 - Thu, May 7 BOC Bocas del Toro PAC Panama City $398 Roundtrip found 16 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOC,to:PAC,departure:4/29/2026TANYT&leg2=from:PAC,to:BOC,departure:5/7/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:397.50&airProductToken=AQomCiQIwWISBDEwMjEYwRMgjxAo5taLAzCi14sDOFlAAFgBcgNZT1cSDAgBEAEYASoCR1AyABgBIgQIARABKAIoAygEMAE) ![APG Distribution System](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/GP.gif) Mon, Apr 13 - Tue, Apr 14 BOC Bocas del Toro PAC Panama City $408 Roundtrip found 20 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BOC,to:PAC,departure:4/13/2026TANYT&leg2=from:PAC,to:BOC,departure:4/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:407.60&airProductToken=AQoxCi8IwWISBDEwMjMYwRMgjxAoo6GKAzDfoYoDOFlAAFgBcgNZT1d6CQi3oAESAzk4MRIKCAEQARgBKgJHUBgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Columbus (CMH) to Panama City (PTY) ### October is typically the cheapest month to fly From $359 - $1,068 per traveler. ## Frequently asked questions ### What month is the cheapest to fly to Santiago? ### Which US cities fly direct to Santiago? > - Miami > - Orlando > - Los Angeles > - Washington > - New York ### How to find a cheap flight to Santiago? ### How to get a cheap last-minute flight to Santiago? ### How far in advance should I book a flight to Santiago? ### Which day of the week is the cheapest day to buy a plane ticket to Santiago? ### Which airlines fly to Santiago? > - Copa Airlines - 932 flights to Santiago each month, including 932 flights to Tocumen Intl. Airport (PTY) per month. > - United Airlines - 152 flights to Santiago each month, including 152 flights to Tocumen Intl. Airport (PTY) per month. > - Delta Air Lines - 30 flights to Santiago each month, including 30 flights to Tocumen Intl. Airport (PTY) per month. ### Where do you fly into Santiago? ### How far is the airport from central Santiago? ### Can I save money by booking a Santiago trip package? ### Can I change or cancel my flight to Santiago? \*Flight schedules are subject to change. \*Available to One Key members. ## Book with confidence # Tips to find the cheapest flights to Santiago **The cheapest day to fly** Get started finding a cheap flight to Santiago on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you. **The cheapest month to fly** May is the cheapest month to fly to Santiago. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Santiago. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute. **The most affordable time to book a flight** Typically, a Sunday can be the cheapest time to book a flight to Santiago, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation. **The cheapest round-trip tickets to Santiago** The lowest price for round-trip flights to Santiago in 2026 starts from from $322, while one-way tickets start from from $146\. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Santiago. If you have a preferred departure time or airline, you can use the handy filters to customize your search. **The cheapest airlines flying to Santiago** Euroairlines, Hahn Air Technologies, APG Distribution System are just some of the airlines that can typically offer cheap tickets to Santiago. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Santiago and countless more destinations worldwide. **The most affordable airports to fly into** To view the cheapest airports to fly into for Santiago, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Santiago. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia. **Save with a package** With Expedia's amazing [package deals](https://www.expedia.com/package-deals), you could save hundreds of dollars by booking your Santiago plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving. **Date flexibility for the cheapest flights to Santiago** If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Santiago. **Stopover savings** The cheapest tickets to Santiago are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Santiago. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved. **Get Expedia's Price Drop Protection** Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference\*. This gives you peace of mind that you're getting one of the cheapest flights to Santiago for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members. \*Terms apply. **Use our Price Tracking feature** Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Santiago. Simply download the free Expedia app to your smart device and activate Santiago flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices. **Book with Expedia** As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Santiago. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. ## Travel information | Destination airport | Tocumen Intl. | | ----------------------------- | ------------- | | Destination airport IATA code | PTY | | Destination city name | Panama City | | Roundtrip price | $321 | ## Trending flights to Santiago Prices were available within the past 7 days and start at $146 for one-way flights and $322 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Fri, May 22 - Sat, Jun 6 MIA Miami PTY Panama City $322 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MIA,to:PTY,departure:5/22/2026TANYT&leg2=from:PTY,to:MIA,departure:6/6/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:321.13&airProductToken=AQoxCi8Iw5oBEgMyMjcYjAIg78QBKMXZjQMw_9qNAzhUQABYAWoDQkFTcghUTEE0VFoyUwoxCi8Iw5oBEgMyNDAY78QBIIwCKLmBjwMw-4KPAzhUQABYAWoDQkFTcghUTEE5T1oyUxIKCAEQARgBKgJDTRgBIgQIARABKAIoAygEMAs) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Family Hotels in Veraguas ](https://www.expedia.com/Destinations-In-Veraguas-Family-Hotel.0-0-d6246233-tFamilyHotel.Hotel-Filter-Destinations) - [Resorts in Veraguas ](https://www.expedia.com/Veraguas-Resorts.d6246233-aaResorts.Travel-Guide-Accommodation) - 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