Cherokee Seneca Vacations from $260

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Your Cherokee Seneca Vacation

Whether you're coming for its history or walking, the neighborhood of Cherokee Seneca has plenty to keep you busy. Experience all of this and more with ease by booking a Cherokee Seneca vacation package. Some leading nearby attractions to see during your trip to Cherokee Seneca include Louisville Mega Cavern, Louisville Zoo and Louisville Waterfront Park. Expedia can help turn your ideal Cherokee Seneca vacation into reality, whatever your budget or travel plans.

The Latest Cherokee Seneca Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Trail Hotel

The Trail Hotel

4 out of 5
Save 100% on your flight
Price was $381, price is now $260 per person
$260
per person
Jan 17 - Jan 19
found 3 hours ago
Roundtrip flight included
Miami (MIA) to Louisville (SDF)
8.6/10 Excellent! (91 reviews)
Rooms were great and staff was wonderful.

Reviewed on Nov 22, 2025

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

3.5 out of 5
Save 100% on your flight
Price was $906, price is now $467 per person
$467
per person
Jan 6 - Jan 11
found 23 hours ago
Roundtrip flight included
New York (NYC) to Louisville (SDF)
8.2/10 Very Good! (1,002 reviews)
This is an excellent venue except for the smoky air. While we had a king non-smoking room unfortunately air is circulating throughout the facility and the unpleasant cigarette smoke smell permeates all rooms. If that doesn’t bother you you’re going to enjoy your stay.

Reviewed on Nov 25, 2025

Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
Downtown Louisville
Price was $693, price is now $505 per person
$505
per person
Jan 16 - Jan 19
found 1 day ago
Roundtrip flight included
Miami (MIA) to Louisville (SDF)
8.8/10 Excellent! (1,005 reviews)
Loved big screen tv and the beds were very comgortable.

Reviewed on Nov 24, 2025

Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
Downtown Louisville
Price was $661, price is now $488 per person
$488
per person
Jan 16 - Jan 19
found 1 day ago
Roundtrip flight included
Miami (MIA) to Louisville (SDF)
9/10 Wonderful! (1,003 reviews)
I like the shower and that it had a place to prop your foot while shaving. It was great having an empty fridge where I could store leftovers. I liked the layout of the room and there was plenty of charging plugs. On top of all of that the location was pretty great.

Reviewed on Nov 19, 2025

Holiday Inn Louisville Airport South by IHG

Holiday Inn Louisville Airport South by IHG

3 out of 5
Price was $546, price is now $406 per person
$406
per person
Jan 16 - Jan 19
found 1 day ago
Roundtrip flight included
Miami (MIA) to Louisville (SDF)
8.8/10 Excellent! (765 reviews)
Great customer service 👏

Reviewed on Nov 26, 2025

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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Cherokee Seneca
Louisville showing signage and street scenes as well as a small group of people

Downtown Louisville

4 out of top 10 points of interest in this area
4/5(1,812 area reviews)

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Find hotels in Downtown Louisville

Cherokee Seneca Hotel Deals

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $110 total per night from Dec 10 to Dec 11
$110 total
Dec 10 - Dec 11
Total with taxes and fees
8.8/10 Excellent! (3,811 reviews)
Room was spotless and with a great view

Reviewed on Nov 28, 2025

Galt House Hotel Trademark Collection by Wyndham
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $85 total per night from Dec 2 to Dec 3
$85 total
Dec 2 - Dec 3
Total with taxes and fees
8.8/10 Excellent! (994 reviews)
Clean and spacious rooms, good staff, good location. Stay away from Al's Kitchen, however.

Reviewed on Nov 25, 2025

Crowne Plaza Louisville Airport Expo Ctr by IHG
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $234 total per night from Nov 30 to Dec 1
$234 total
Nov 30 - Dec 1
Total with taxes and fees
9.2/10 Wonderful! (1,701 reviews)
Clean and friendly staff. Hotel was close to lots of things to do.

Reviewed on Nov 26, 2025

Omni Louisville Hotel
See all 2,089 properties in Cherokee Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Cherokee Seneca

Kissing trees in Cherokee Park

Cherokee Park

Cherokee Park is just one of the places to see in Louisville, so why not enjoy the other things to explore during your travels? Stroll along the area's riverfront or experience its great live music.

Cherokee Park
Ky Derby festival balloon glow.

Kentucky Exposition Center

Learn about the events happening at Kentucky Exposition Center during your trip to Louisville. Experience the area's great live music and lively festivals.

Kentucky Exposition Center
Churchill Downs showing horseriding and land animals as well as a small group of people

Churchill Downs

Find more than mint juleps to enjoy at this iconic racetrack, best known as the annual host of the Kentucky Derby.

Churchill Downs

Things to do

Kentucky Derby Museum

Kentucky Derby Museum - General Admission and Guided Track Visit

$22
per adult
90% of travellers recommend
Kentucky Derby Museum - General Admission and Guided Track Visit
Derby City Ghosts: Louisville Hauntings Tour

Lace, Lunacy, and Loss: Louisville Ghost Tours

$32
per adult
Lace, Lunacy, and Loss: Louisville Ghost Tours
Kentucky Derby Museum - Admission with Guided Track Visit

Kentucky Derby Museum - Admission with Guided Track Visit

$22
per adult
100% of travellers recommend
Kentucky Derby Museum - Admission with Guided Track Visit
See all activities in Louisville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.