Title: Top 10 Hotels in Clarksdale, MO from $66 - Competitive Prices | Expedia.com

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## Go beyond your typical stay in Clarksdale

Family friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&travelerType=family_friendly)

Cabin

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&lodging=CABIN)

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=PETS)

Pool

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=POOL)

Hot tub

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=HOT_TUB)

Apart­ment

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&lodging=APARTMENT)

## Check prices for these dates

Tonight

[Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Clarksdale hotels

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Theme Suite with Whirlpool | Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stoney Creek Hotel St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(1,625 reviews)

"Great place for family big rooms pool is nice centrally located "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

$124 nightly

$143 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Accessible (Sofa Sleeper, Roll-in Shower, 2 Rooms) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites St Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(1,005 reviews)

"Loved this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vicki

$110 nightly

$127 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/w3000h1897x0y3-644920c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### My Place Hotel St Joseph MO

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(243 reviews)

"Clean rooms, friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

$88 nightly

$102 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/d40daa76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(812 reviews)

"Clean room, nice people"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brianna

$118 nightly

$137 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/b90af532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/d2e48a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

St. Joseph

8.2/10

Very Good

(675 reviews)

"Staff was very friendly. Kasey made checking in a breeze. She was so helpful and kind. Room was comfortable and clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$83 nightly

$96 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/965f4dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/28b1385b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

Cameron

8.4/10

Very Good

(640 reviews)

"The room was clean, quiet and bed was very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vickie

$107 nightly

$118 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/33a59e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Hotel by Best Western Cameron

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

Cameron

8.2/10

Very Good

(1,001 reviews)

"Very nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$70 nightly

$77 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/e0d9868d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

St. Joseph

9.6/10

Exceptional

(485 reviews)

"Clean room and friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

$105 nightly

$123 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(110 reviews)

"Staff was wonderful. Rooms clean and equipped with needed kitchen supplies. Really nice new hotel. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$110 nightly

$127 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/c6efac2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/873f6f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/96bdd18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/79d2554d_edited_dfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Cameron, MO

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

Cameron

7.0/10

Good

(298 reviews)

"The staff was in great spirits, helped with extra sheets and a pillow when we asked. They checked on us which was appreciated. The smoke alarms were taken down, the mirrors were not cleaned in a long time. The residents were terrifying. The mattress cover looked like there had been a massacre. We will not be back. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jason

$59 nightly

$66 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/cc53b139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

Cameron

8.8/10

Excellent

(1,002 reviews)

"Clean room, friendly staff, good location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$80 nightly

$89 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Room, 1 King Bed, Hot Tub | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/d3b97e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/3d5ca308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

Cameron

8.4/10

Very Good

(651 reviews)

"The room was very clean, beds were very comfortable . Staff were friendly and helpful. It was almost like staying with family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$76 nightly

$83 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Smoking, Ground Floor | Free cribs/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

Cameron

6.2/10

(162 reviews)

"Lovely staff. Very helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Colleen

$68 nightly

$75 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6685816e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6328c1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AmeriStay Inn

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

St. Joseph

5.4/10

(721 reviews)

"Property needs quite a bit of work to bring it up to standards."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$71 nightly

$83 total

Apr 22 - Apr 23

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/8fa32ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f4c6728d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vineyard Mansion & Carriage House Bed & Breakfast

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(201 reviews)

"Very friendly staff willing to help anyway they can. Stayed two nights very easy access and felt more like home than a hotel would have."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donald

$147 nightly

$157 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, Ensuite (Single Queen ) | Bathroom | Combined shower/tub, hair dryer, towels, soap](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/w1000h963x0y0-b16dd7a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Whiskey Mansion

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(589 reviews)

"Holly was a wonderful host for our stay!! Breakfasts felt so fancy and made with love, definitely coming back again! The decor and vibe of the place was so beautiful :)"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

$122 nightly

$142 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | Living area | 100-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f2b04a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | In-room dining](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/9ed1ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cameron Suites

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

Cameron

$201 nightly

$220 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/f99f9ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/d7bb37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/eb107eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Saint Joseph, MO

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

St. Joseph

4.6/10

(1,000 reviews)

"Staff was very nice, very clean, pet friendly. Will definitely stay here again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

$65 nightly

$75 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Clarksdale Hotel Reviews

![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent

"Very clean, conveniently located and comfortable "

[](https://expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg)

### My Place Hotel St Joseph MO

10/10 Excellent

"Rooms clean and spacious with kitchenette "

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218_y.jpg)

### Drury Inn & Suites St Joseph

10/10 Excellent

"Clean rooms, accommodating staff, close to food and gas for travelers. The pool is huge (not heated) but indoor. "

[](https://expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Super 8 by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4_y.jpg)

### Super 8 by Wyndham Cameron

10/10 Excellent

"Very clean, comfortable beds. Will stay here again."

[](https://expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Home2 Suites By Hilton St. Joseph](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6_y.jpg)

### Home2 Suites By Hilton St. Joseph

10/10 Excellent

"Staff is friendly and always helpful. "

[](https://expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e_y.jpg)

### Stoney Creek Hotel St. Joseph

10/10 Excellent

"Clean and great service. Hot tub was nice too"

[](https://expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b_y.jpg)

### SureStay Hotel by Best Western Cameron

8/10 Good

"This is an older, basic hotel. Having said that, the hotel is pet friendly and our room had everything we needed including a comfortable bed and great shower. The electrical stuff (lights, outlets) was quirky as was the satellite tv service which had to be disconnected and reconnected every time the tv was turned off. There is a truck stop/gas station/convenience store nearby but the room was so quiet that was not an issue at all. Parking is convenient even for vehicles pulling trailers. There is a lot of adjacent open space for dog walking. "

[](https://expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg)

### Red Roof Inn Cameron

10/10 Excellent

"Yes"

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Days Inn by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/cdd2480a_y.jpg)

### Days Inn by Wyndham Cameron

10/10 Excellent

"We had a hard time finding the motel, thought it was on the freeway. It was after dark and once we found it, the entrance was equally hard to find. Almost went over a curb as the motel parking lot next door did not connect. Staff was exceptionally friendly and helpful. We would stay here again."

[](https://expedia.com/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information)

## More cheap stays in Clarksdale

![Motel 6 Saint Joseph, MO](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Saint Joseph, MO

4021 Frederick Ave St. Joseph MO

$65 nightly

$75 total

Mar 30 - Mar 31

Total with taxes and fees

4.6/10 (1,000 reviews)

[](https://expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### SureStay Hotel by Best Western Cameron

2210 US Highway 36 Cameron MO

$70 nightly

$77 total

Apr 4 - Apr 5

Total with taxes and fees

8.2/10 Very Good! (1,001 reviews)

[](https://expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![AmeriStay Inn](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO

$71 nightly

$83 total

Apr 22 - Apr 23

Total with taxes and fees

5.4/10 (721 reviews)

[](https://expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Roof Inn Cameron

501 Northland Drive Cameron MO

$80 nightly

$89 total

Mar 30 - Mar 31

Total with taxes and fees

8.8/10 Excellent! (1,002 reviews)

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph MO

$83 nightly

$96 total

Apr 12 - Apr 13

Total with taxes and fees

8.2/10 Very Good! (675 reviews)

[](https://expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### My Place Hotel St Joseph MO

3621 N Village Dr St. Joseph MO

$88 nightly

$102 total

Apr 19 - Apr 20

Total with taxes and fees

9.2/10 Wonderful! (243 reviews)

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

## Hotels in Clarksdale with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

6 properties

[](https://expedia.com/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

27 properties

[](https://expedia.com/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Clarksdale?

> This central area is the heart of Clarksdale's blues music scene and is very walkable. You'll find a high concentration of blues clubs, juke joints, and historic markers. The Delta Blues Museum is also located downtown, offering a deep dive into the region's musical heritage. Many of the city's unique restaurants and shops are clustered here, making it convenient for exploring on foot.
> 
>   
> Solo travelers and couples often find this area ideal due to its lively evenings and the ease of accessing various entertainment options.

### When is the best time to go to Clarksdale?

> Spring brings mild temperatures, typically ranging from the 60s to 70s Fahrenheit, with blooming wildflowers and lush greenery. It's an excellent time for couples who enjoy outdoor activities like hiking or picnicking in nearby parks without the intense summer heat. The comfortable climate makes strolling through the small town center enjoyable.
> 
>   
> Fall also provides agreeable temperatures, usually in the 60s, along with the scenic beauty of changing leaves. This period is ideal for solo travelers or those seeking a quiet retreat. The cooler weather is superb for visiting local antique shops, exploring historical sites, or simply enjoying a warm drink at a local coffee shop.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Clarksdale hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Clarksdale hotel?

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- [Flights to Helena ](https://www.expedia.com/Cheap-Flights-To-Helena.d6179513.Travel-Guide-Flights)
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- [Cool Crest Garden Golf ](https://www.expedia.com/Cool-Crest-Garden-Golf-St-Joseph.d553248621532648958.Vacation-Attraction)
- [Glore Psychiatric Museum ](https://www.expedia.com/Glore-Psychiatric-Museum-St-Joseph.d553248621532648959.Vacation-Attraction)
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- [Mount Mora Cemetery ](https://www.expedia.com/Mount-Mora-Cemetery-St-Joseph.d553248621532648954.Vacation-Attraction)
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- [St. Joseph Vacation Rentals ](https://www.expedia.com/St-Joseph-Vacation-Rentals.d9934.Travel-Guide-VacationRentals)