Default HTG hotel image

Find hotels in Clarksdale, MO from $69

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 22 - Oct 23
Tomorrow
Oct 23 - Oct 24
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Filter by

Star rating

Guest rating

Our top choices for Clarksdale hotels

An indoor swimming pool with clear lane markings, a lifeguard chair, and a pool ladder.
A neatly made bed with white linens and a headboard.
A Hampton Inn by Hilton building with a modern facade, large windows, and a well-lit entrance.
A reception desk with a clock, a framed picture, and a wall with a 'smile' sign.

1. Hampton Inn St. Joseph

Hampton Inn St. Joseph
St. Joseph
United States
Gary
$80 nightly
$92 total
Nov 1 - Nov 2
Total with taxes and fees
Hampton Inn St. Joseph
A hotel room with a bed, a sofa, a small table, a microwave, and a TV.
A Holiday Inn Express & Suites sign with a building in the background.
A coffee station with two coffee machines and a sign that reads 'MUST. HAVE. COFFEE.'
A gym with treadmills, elliptical machines, and weightlifting equipment.

2. Holiday Inn Express Hotel & Suites St. Joseph by IHG

Holiday Inn Express Hotel & Suites St. Joseph by IHG
St. Joseph
United States
Teresa
$107 nightly
$124 total
Nov 22 - Nov 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites St. Joseph by IHG
A pool area with a rock formation backdrop, a wooden post, and a sign indicating a clinic.
A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.
A wooden reception desk with a moose mural, a mounted cow head, and a framed map on the wall.
A cozy log cabin interior with a fireplace, wooden furniture, and a television.

3. Stoney Creek Hotel St. Joseph

Stoney Creek Hotel St. Joseph
St. Joseph
United States
Amy
$105 nightly
$122 total
Oct 25 - Oct 26
Total with taxes and fees
Stoney Creek Hotel St. Joseph
A lobby with a seating area, a reception desk, and a chandelier.
A Drury Inn & Suites hotel with a modern architectural design, featuring a covered entrance and a parking lot.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A hotel lobby with a reception desk, seating area, and a refrigerator.

4. Drury Inn & Suites St Joseph

Drury Inn & Suites St Joseph
St. Joseph
United States
Kevin
$110 nightly
$127 total
Oct 27 - Oct 28
Total with taxes and fees
Drury Inn & Suites St Joseph
A hotel room with two beds, a desk, a television, and a bathroom visible through an open door.
A modern kitchen with granite countertops, wooden cabinets, and a central island.
A 8 ft. clearance hotel entrance with a SureStay sign, brick exterior, and potted plants.
A hotel with a covered outdoor area, a brick building, and a sign for a nearby Subway.

5. SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron
Cameron
United States
Richard
$78 nightly
$86 total
Oct 29 - Oct 30
Total with taxes and fees
SureStay Hotel by Best Western Cameron
A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.
An indoor swimming pool with clear water, surrounded by white plastic chairs and tables, and a lifeguard sign on the wall.
A hotel room with a bed, a desk with a computer, a chair, a TV, and a window with a view.
A two-story building with a covered parking area and a brick facade.

6. Super 8 by Wyndham Cameron

Super 8 by Wyndham Cameron
Cameron
United States
richard
$88 nightly
$97 total
Oct 30 - Oct 31
Total with taxes and fees
Super 8 by Wyndham Cameron
A compact kitchen with a microwave, sink, and refrigerator.
Exterior
A hotel room with a bed, a desk with a TV, a chair, and a window with curtains.
A modern hotel lobby with a reception desk, seating area, and a large window with curtains.

7. Woodspring Suites St. Joseph

Woodspring Suites St. Joseph
St. Joseph
United States
Robert
$94 nightly
$109 total
Oct 25 - Oct 26
Total with taxes and fees
Woodspring Suites St. Joseph
A modern living room with a blue sofa, a fireplace, and a stone accent wall.
An indoor swimming pool with clear water, a lifeguard chair, and a pool ladder.
A modern hotel lobby with a stone fireplace, blue sofas, a round table, and large windows offering a view of the parking lot.
A restaurant with a long wooden table, chairs, and a bar area.

8. Fairfield Inn & Suites by Marriott St. Joseph

Fairfield Inn & Suites by Marriott St. Joseph
St. Joseph
United States
Chris
$105 nightly
$122 total
Nov 1 - Nov 2
Total with taxes and fees
Fairfield Inn & Suites by Marriott St. Joseph
A spacious kitchen with wooden cabinets, a dining area with a table and chairs, and a hallway leading to another room.
A hotel reception area with a reception desk, a telephone, and a sign indicating free Wi-Fi in all rooms.
A hotel room with a bed, a desk, a chair, a television, and an air conditioning unit.
A hotel room with a bed, a desk with a computer, a microwave, a red chair, and a window with curtains.

9. Red Roof Inn Cameron

Red Roof Inn Cameron
Cameron
United States
Bret
$91 nightly
$101 total
Nov 1 - Nov 2
Total with taxes and fees
Red Roof Inn Cameron
Private kitchen
Breakfast meal
A modern restaurant with a bar area, seating arrangements, and a kitchen in the background.
A multi-story hotel with a 'My Place' sign, featuring a stone facade and a covered entrance.

10. My Place Hotel St Joseph MO

My Place Hotel St Joseph MO
St. Joseph
United States
paul
$83 nightly
$96 total
Nov 22 - Nov 23
Total with taxes and fees
My Place Hotel St Joseph MO
A swimming pool with a hot tub, a ladder, and a slide.
A hotel room with a large bed, two bedside tables with lamps, a desk, and a chair.
A reception area with a coffee station, a potted plant, and a banner promoting breakfast.
A reception area with a reception desk, a plant, a coffee station, and a sign for breakfast.

11. Quality Inn Cameron

Quality Inn Cameron
Cameron
United States
Barbara
$102 nightly
$113 total
Nov 22 - Nov 23
Total with taxes and fees
Quality Inn Cameron
A hotel room with a sofa, two beds, a patterned ottoman, a wall art piece, and a window with a view.
A compact hotel room with a kitchenette, a dining area, and a TV.
A hotel dining area with multiple seating options including booths and tables, a flat-screen TV mounted on the wall, and a self-service beverage station.
A hotel room with a desk, chair, television, sofa, ottoman, and a window with a patterned curtain.

12. Home2 Suites By Hilton St. Joseph

Home2 Suites By Hilton St. Joseph
St. Joseph
United States
Lindsey
$135 nightly
$156 total
Nov 1 - Nov 2
Total with taxes and fees
Home2 Suites By Hilton St. Joseph
A hotel room with two beds, a desk, a chair, and a television.
A hallway with a 7UP vending machine, white doors, and a brown mat.
A vending machine with snacks and a 7UP machine in a hallway with a staircase.
A hotel reception area with a wooden counter, a coffee machine, a phone, and a television.

13. Motel 6 Saint Joseph, MO

Motel 6 Saint Joseph, MO
St. Joseph
United States
Picaso
$60 nightly
$69 total
Nov 8 - Nov 9
Total with taxes and fees
Motel 6 Saint Joseph, MO
A living room with two sofas, a coffee table, a lamp, and a potted plant.
A hotel room with a large bed, a desk, a television, and a window with curtains.
A hotel with a covered outdoor seating area, a clock tower, and a well-lit facade.
An indoor swimming pool with clear blue water, surrounded by white lounge chairs and a wooden ceiling.

14. Days Inn by Wyndham Cameron

Days Inn by Wyndham Cameron
Cameron
United States
Deborah
$71 nightly
$78 total
Nov 1 - Nov 2
Total with taxes and fees
Days Inn by Wyndham Cameron
A hotel room with a large bed, a red wall, and a cityscape painting above the bed.
A vending machine with a Pepsi logo and a water dispenser with instructions.
A hotel room with a television, a lamp, a microwave, and a desk with a chair.
A reception desk with a clock, decorative wall art, and American flags.

15. AmeriStay Inn

AmeriStay Inn
St. Joseph
United States
Jennifer
$75 nightly
$87 total
Oct 26 - Oct 27
Total with taxes and fees
AmeriStay Inn
A large, historic brick building with a prominent tower and a grand entrance.
A traditional room with a fireplace, ornate chandelier, and classic furniture.
A traditional interior with a fireplace, wooden furniture, and a chandelier.
A grand room with a red patterned carpet, a large potted plant, a wooden staircase, and a chandelier.

16. Vineyard Mansion & Carriage House Bed & Breakfast

Vineyard Mansion & Carriage House Bed & Breakfast
St. Joseph
United States
Keith
$142 nightly
$151 total
Oct 23 - Oct 24
Total with taxes and fees
Vineyard Mansion & Carriage House Bed & Breakfast
A large brick building with multiple windows and a covered porch area.
A covered porch with columns, potted plants, and a brick wall.
A grand entrance with a stained glass window, a red upholstered sofa, and a wooden chair.
A traditional interior with a fireplace, a wooden staircase, and a patterned floor.

17. Whiskey Mansion

Whiskey Mansion
St. Joseph
United States
Lana
$136 nightly
$157 total
Oct 25 - Oct 26
Total with taxes and fees
Whiskey Mansion
A gazebo with a metal roof and wooden benches.
A hotel room with two beds, a nightstand with a lamp, a small table, a mirror, and a window.
A living room with a leather sofa, a glass coffee table, and various potted plants.
A lobby with a fireplace, a table with four chairs, and a patterned carpet.

18. Econo Lodge Cameron

Econo Lodge Cameron
Cameron
United States
Barbara
$77 nightly
$85 total
Nov 22 - Nov 23
Total with taxes and fees
Econo Lodge Cameron
A balcony with a stainless steel refrigerator, a wicker chair, and an air conditioning unit.
A building with a covered entrance, a small patio with chairs, and a window with blinds.
A cluttered office space with a desk, computer, printer, and various office supplies.
A motel with a large sign, a parking lot, and a building with a sloped roof.

19. Capri Motel By OYO Elwood, Wathena

Capri Motel By OYO Elwood, Wathena
Wathena
United States
Glen
$83 nightly
$90 total
Oct 31 - Nov 1
Total with taxes and fees
Capri Motel By OYO Elwood, Wathena
A reception desk with a "WELCOME" sign, a clock, and a mirror.
A kitchenette with a coffee machine, a trash can, and a sign indicating coffee service hours.
A compact kitchenette with a microwave, sink, and small refrigerator.
A hotel room with two beds, a desk with a chair, a microwave, a TV, and a small shelf with toiletries.

20. Motel 6 Cameron, MO

Motel 6 Cameron, MO
Cameron
United States
Mark
$75 nightly
$82 total
Oct 24 - Oct 25
Total with taxes and fees
Motel 6 Cameron, MO
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Clarksdale Hotel Reviews

My Place Hotel St Joseph MO

My Place Hotel St Joseph MO

8/10 Good
"The aesthetics were not great, but the accommodations and cleanliness made up for it!"
Jeanne 1-night trip
Posted 1 hour ago
My Place Hotel St Joseph MO
SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron

10/10 Excellent
"Great stay and pets stay free. Also the property was really cool"
Joshua 1-night trip
Posted 6 hours ago
SureStay Hotel by Best Western Cameron
Woodspring Suites St. Joseph

Woodspring Suites St. Joseph

10/10 Excellent
"New Hotel, only open a couple weeks. So, very clean and very nice. Staff was very friendly and helpful! Could of used couple more towels. Not a fan of the moisture barrier mattress cover, makes me sweat."
paula 1-night trip
Posted 2 days ago
Woodspring Suites St. Joseph
Holiday Inn Express Hotel & Suites St. Joseph by IHG

Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent
"Best hotel in a 2-week trip. Friendly staff. Ultra clean. Great view. Extremely comfortable and clean furniture. Other hotels should pay attention."
robert 1-night trip
Posted 2 days ago
Holiday Inn Express Hotel & Suites St. Joseph by IHG
Super 8 by Wyndham Cameron

Super 8 by Wyndham Cameron

8/10 Good
"N/A"
Eric 2-night trip
Posted 4 days ago
Super 8 by Wyndham Cameron
Red Roof Inn Cameron

Red Roof Inn Cameron

10/10 Excellent
"Check in was nice and the hotel was very clean. Coffee was instant but still okay. Appreciate having a dog friendly room"
shamera 1-night trip
Posted 4 days ago
Red Roof Inn Cameron
Whiskey Mansion

Whiskey Mansion

10/10 Excellent
"Nos gustó mucho, me volvería a quedar"
RAFAEL 4-night trip
Posted 7 days ago
Whiskey Mansion
Home2 Suites By Hilton St. Joseph

Home2 Suites By Hilton St. Joseph

10/10 Excellent
"👍"
Thomas 3-night trip
Posted 7 days ago
Home2 Suites By Hilton St. Joseph
Vineyard Mansion & Carriage House Bed & Breakfast

Vineyard Mansion & Carriage House Bed & Breakfast

10/10 Excellent
"Wonderful and charming place to stay"
Dennis 1-night trip
Posted 11 days ago
Vineyard Mansion & Carriage House Bed & Breakfast

More cheap stays in Clarksdale

SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron

2210 US Highway 36 Cameron MO
$78 nightly
$86 total
Oct 29 - Oct 30
Total with taxes and fees
8/10 Very Good! (1,002 reviews)
SureStay Hotel by Best Western Cameron
AmeriStay Inn

AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO
$75 nightly
$87 total
Oct 26 - Oct 27
Total with taxes and fees
AmeriStay Inn
Hampton Inn St. Joseph

Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph MO
$80 nightly
$92 total
Nov 1 - Nov 2
Total with taxes and fees
8.2/10 Very Good! (768 reviews)
Hampton Inn St. Joseph
My Place Hotel St Joseph MO

My Place Hotel St Joseph MO

3621 N Village Dr St. Joseph MO
$83 nightly
$96 total
Nov 22 - Nov 23
Total with taxes and fees
9.2/10 Wonderful! (380 reviews)
My Place Hotel St Joseph MO
Red Roof Inn Cameron

Red Roof Inn Cameron

501 Northland Drive Cameron MO
$91 nightly
$101 total
Nov 1 - Nov 2
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
Red Roof Inn Cameron
Quality Inn Cameron

Quality Inn Cameron

1803 Comfort Ln Cameron MO
$102 nightly
$113 total
Nov 22 - Nov 23
Total with taxes and fees
Quality Inn Cameron

Hotels in Clarksdale with star-rating

Frequently asked questions

What is the best area to stay in Clarksdale?
The best area to stay in Clarksdale is the downtown area, particularly around Yazoo Avenue and Delta Avenue, which offers the most concentrated experience for visitors.This central area is the heart of Clarksdale's blues music scene and is very walkable. You'll find a high concentration of blues clubs, juke joints, and historic markers. The Delta Blues Museum is also located downtown, offering a deep dive into the region's musical heritage. Many of the city's unique restaurants and shops are clustered here, making it convenient for exploring on foot.Solo travelers and couples often find this area ideal due to its lively evenings and the ease of accessing various entertainment options.
When is the best time to go to Clarksdale?
The best time to go to Clarksdale, Missouri, is during the spring (late April to early June) and fall (September to October) months. These seasons offer the most pleasant weather for exploring the area.Spring brings mild temperatures, typically ranging from the 60s to 70s Fahrenheit, with blooming wildflowers and lush greenery. It's an excellent time for couples who enjoy outdoor activities like hiking or picnicking in nearby parks without the intense summer heat. The comfortable climate makes strolling through the small town center enjoyable.Fall also provides agreeable temperatures, usually in the 60s, along with the scenic beauty of changing leaves. This period is ideal for solo travelers or those seeking a quiet retreat. The cooler weather is superb for visiting local antique shops, exploring historical sites, or simply enjoying a warm drink at a local coffee shop.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Clarksdale.
How much is the nightly rate at a Clarksdale hotel?
Prices for hotels in Clarksdale often vary, but you can find a great deal from $69 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia