Title: Top 10 Hotels in Clarksdale, MO from $66 - Competitive Prices | Expedia.com

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## Go beyond your typical stay in Clarksdale

Cabin

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=CABIN)

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=PETS)

Family friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&travelerType=family_friendly)

Pool

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=POOL)

Hot tub

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=HOT_TUB)

Apart­ment

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=APARTMENT)

## Check prices for these dates

Tonight

[Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Clarksdale hotels

![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/965f4dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

Cameron

8.4/10

Very Good

(640 reviews)

"The room was clean, quiet and bed was very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vickie

$103 nightly

$115 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/d2e48a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/b90af532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

St. Joseph

8.2/10

Very Good

(675 reviews)

"Staff was very friendly. Kasey made checking in a breeze. She was so helpful and kind. Room was comfortable and clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$83 nightly

$96 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/dc26a342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

Cameron

8.8/10

Excellent

(1,007 reviews)

"Clean room, friendly staff, good location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$80 nightly

$89 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/60106125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Hotel by Best Western Cameron

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

Cameron

8.2/10

Very Good

(1,000 reviews)

"Very nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$70 nightly

$77 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites St Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(1,005 reviews)

"Loved this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vicki

$110 nightly

$127 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Room, 1 King Bed, Hot Tub | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/d3b97e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fd3d7861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

Cameron

8.4/10

Very Good

(651 reviews)

"The room was very clean, beds were very comfortable . Staff were friendly and helpful. It was almost like staying with family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$76 nightly

$83 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### My Place Hotel St Joseph MO

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(244 reviews)

"Clean rooms, friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

$88 nightly

$102 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(110 reviews)

"Staff is friendly and always helpful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

$110 nightly

$127 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Theme Suite with Whirlpool | Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stoney Creek Hotel St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(1,627 reviews)

"Great place for family big rooms pool is nice centrally located "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

$124 nightly

$143 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/c6efac2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3cfc730e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/873f6f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/96bdd18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Cameron, MO

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

Cameron

7.0/10

Good

(298 reviews)

"The staff was in great spirits, helped with extra sheets and a pillow when we asked. They checked on us which was appreciated. The smoke alarms were taken down, the mirrors were not cleaned in a long time. The residents were terrifying. The mattress cover looked like there had been a massacre. We will not be back. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jason

$59 nightly

$66 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/71deeec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(813 reviews)

"Wonderful stay with a restaurant quality breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cristine

$118 nightly

$137 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/e03c581b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/8fa32ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vineyard Mansion & Carriage House Bed & Breakfast

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(201 reviews)

"Very friendly staff willing to help anyway they can. Stayed two nights very easy access and felt more like home than a hotel would have."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donald

$147 nightly

$157 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/c9cd0093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, Ensuite (Single Queen ) | Bathroom | Combined shower/tub, hair dryer, towels, soap](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/w1000h963x0y0-b16dd7a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Whiskey Mansion

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(590 reviews)

"Holly was a wonderful host for our stay!! Breakfasts felt so fancy and made with love, definitely coming back again! The decor and vibe of the place was so beautiful :)"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

$124 nightly

$143 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/e0d9868d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/2dbfeb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

St. Joseph

9.6/10

Exceptional

(486 reviews)

"Clean room and friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

$105 nightly

$123 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Smoking, Ground Floor | Free cribs/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

Cameron

6.2/10

(162 reviews)

"Lovely staff. Very helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Colleen

$68 nightly

$75 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/w4032h2718x0y306-05e60f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | Living area | 100-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | In-room dining](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/9ed1ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cameron Suites

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

Cameron

$201 nightly

$220 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6685816e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/10d352cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AmeriStay Inn

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

St. Joseph

5.4/10

(722 reviews)

"Property needs quite a bit of work to bring it up to standards."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$71 nightly

$83 total

Apr 22 - Apr 23

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/eb107eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/8fa6ae99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/d7bb37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Saint Joseph, MO

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

St. Joseph

4.6/10

(1,000 reviews)

"Staff was very nice, very clean, pet friendly. Will definitely stay here again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

$65 nightly

$75 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Clarksdale Hotel Reviews

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg)

### Red Roof Inn Cameron

8/10 Good

"Yes"

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684_y.jpg)

### Fairfield Inn & Suites by Marriott St. Joseph

10/10 Excellent

"na"

[](https://expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Whiskey Mansion](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64_y.jpg)

### Whiskey Mansion

10/10 Excellent

"Great onsite prepared fresh breakfast. Coleman Hawkins playing in the background. Amazingly restored rooms reflecting 1885 style. Ambiance so great the local come to get away from home. Great job Olin!"

[](https://expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e_y.jpg)

### Stoney Creek Hotel St. Joseph

10/10 Excellent

"Massage chair in room was amazing. "

[](https://expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent

"Very clean, conveniently located and comfortable "

[](https://expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg)

### My Place Hotel St Joseph MO

10/10 Excellent

"Rooms clean and spacious with kitchenette "

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218_y.jpg)

### Drury Inn & Suites St Joseph

10/10 Excellent

"Clean rooms, accommodating staff, close to food and gas for travelers. The pool is huge (not heated) but indoor. "

[](https://expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Super 8 by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4_y.jpg)

### Super 8 by Wyndham Cameron

10/10 Excellent

"Very clean, comfortable beds. Will stay here again."

[](https://expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Home2 Suites By Hilton St. Joseph](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6_y.jpg)

### Home2 Suites By Hilton St. Joseph

10/10 Excellent

"Staff is friendly and always helpful. "

[](https://expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

## More cheap stays in Clarksdale

![Motel 6 Saint Joseph, MO](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Saint Joseph, MO

4021 Frederick Ave St. Joseph MO

$65 nightly

$75 total

Apr 1 - Apr 2

Total with taxes and fees

4.6/10 (1,000 reviews)

[](https://expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### SureStay Hotel by Best Western Cameron

2210 US Highway 36 Cameron MO

$70 nightly

$77 total

Apr 6 - Apr 7

Total with taxes and fees

8.2/10 Very Good! (1,000 reviews)

[](https://expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![AmeriStay Inn](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO

$71 nightly

$83 total

Apr 22 - Apr 23

Total with taxes and fees

5.4/10 (722 reviews)

[](https://expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Roof Inn Cameron

501 Northland Drive Cameron MO

$80 nightly

$89 total

Apr 5 - Apr 6

Total with taxes and fees

8.8/10 Excellent! (1,007 reviews)

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph MO

$83 nightly

$96 total

Apr 5 - Apr 6

Total with taxes and fees

8.2/10 Very Good! (675 reviews)

[](https://expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### My Place Hotel St Joseph MO

3621 N Village Dr St. Joseph MO

$88 nightly

$102 total

Apr 19 - Apr 20

Total with taxes and fees

9.2/10 Wonderful! (244 reviews)

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

## Hotels in Clarksdale with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

6 properties

[](https://expedia.com/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

27 properties

[](https://expedia.com/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Clarksdale?

> This central area is the heart of Clarksdale's blues music scene and is very walkable. You'll find a high concentration of blues clubs, juke joints, and historic markers. The Delta Blues Museum is also located downtown, offering a deep dive into the region's musical heritage. Many of the city's unique restaurants and shops are clustered here, making it convenient for exploring on foot.
> 
>   
> Solo travelers and couples often find this area ideal due to its lively evenings and the ease of accessing various entertainment options.

### When is the best time to go to Clarksdale?

> Spring brings mild temperatures, typically ranging from the 60s to 70s Fahrenheit, with blooming wildflowers and lush greenery. It's an excellent time for couples who enjoy outdoor activities like hiking or picnicking in nearby parks without the intense summer heat. The comfortable climate makes strolling through the small town center enjoyable.
> 
>   
> Fall also provides agreeable temperatures, usually in the 60s, along with the scenic beauty of changing leaves. This period is ideal for solo travelers or those seeking a quiet retreat. The cooler weather is superb for visiting local antique shops, exploring historical sites, or simply enjoying a warm drink at a local coffee shop.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Clarksdale hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Clarksdale hotel?

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