Title: Top 10 Hotels in Clarksdale, MO from $66 - Competitive Prices | Expedia.com

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## Go beyond your typical stay in Clarksdale

Family friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-22&d2=2026-04-22&travelerType=family_friendly)

Cabin

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-22&d2=2026-04-22&lodging=CABIN)

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-22&d2=2026-04-22&amenities=PETS)

Pool

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-22&d2=2026-04-22&amenities=POOL)

Apart­ment

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-22&d2=2026-04-22&lodging=APARTMENT)

## Check prices for these dates

Tonight

[Apr 6 - Apr 7](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Clarksdale hotels

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/33a59e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Hotel by Best Western Cameron

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

Cameron

8.2/10

Very Good

(1,004 reviews)

"Very nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$70 nightly

$77 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/cc53b139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

Cameron

8.8/10

Excellent

(1,007 reviews)

"Clean room, friendly staff, good location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$80 nightly

$89 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/w3000h1897x0y3-644920c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### My Place Hotel St Joseph MO

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(245 reviews)

"Clean rooms, friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

$88 nightly

$102 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/965f4dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

Cameron

8.4/10

Very Good

(641 reviews)

"The room was clean, quiet and bed was very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vickie

$111 nightly

$123 total

May 6 - May 7

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/d2e48a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/923f99c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

St. Joseph

8.2/10

Very Good

(676 reviews)

"Staff was very friendly. Kasey made checking in a breeze. She was so helpful and kind. Room was comfortable and clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$83 nightly

$96 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Room, 1 King Bed, Hot Tub | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fd3d7861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/3d5ca308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

Cameron

8.4/10

Very Good

(653 reviews)

"The room was very clean, beds were very comfortable . Staff were friendly and helpful. It was almost like staying with family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$78 nightly

$86 total

Apr 18 - Apr 19

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(111 reviews)

"Staff is friendly and always helpful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

$110 nightly

$127 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Accessible (Sofa Sleeper, Roll-in Shower, 2 Rooms) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites St Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(1,005 reviews)

"Loved this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vicki

$110 nightly

$127 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Theme Suite with Whirlpool | Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stoney Creek Hotel St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(1,637 reviews)

"Great place for family big rooms pool is nice centrally located "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

$124 nightly

$143 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/71deeec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(814 reviews)

"Wonderful stay with a restaurant quality breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cristine

$114 nightly

$132 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, Ensuite (Single Queen ) | Bathroom | Combined shower/tub, hair dryer, towels, soap](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/c9cd0093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Whiskey Mansion

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(590 reviews)

"Holly was a wonderful host for our stay!! Breakfasts felt so fancy and made with love, definitely coming back again! The decor and vibe of the place was so beautiful :)"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

$120 nightly

$138 total

Apr 22 - Apr 23

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/c6efac2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/873f6f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3cfc730e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/96bdd18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Cameron, MO

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

Cameron

7.0/10

Good

(298 reviews)

"The staff was in great spirits, helped with extra sheets and a pillow when we asked. They checked on us which was appreciated. The smoke alarms were taken down, the mirrors were not cleaned in a long time. The residents were terrifying. The mattress cover looked like there had been a massacre. We will not be back. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jason

$59 nightly

$66 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f4c6728d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/8fa32ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vineyard Mansion & Carriage House Bed & Breakfast

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(201 reviews)

"Very friendly staff willing to help anyway they can. Stayed two nights very easy access and felt more like home than a hotel would have."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donald

$147 nightly

$157 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/2dbfeb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

St. Joseph

9.6/10

Exceptional

(486 reviews)

"Clean room and friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

$105 nightly

$123 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | Living area | 100-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/w4032h2718x0y306-05e60f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | In-room dining](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/9ed1ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cameron Suites

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

Cameron

$201 nightly

$220 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Smoking, Ground Floor | Free cribs/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

Cameron

6.2/10

(162 reviews)

"Lovely staff. Very helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Colleen

$68 nightly

$75 total

Apr 25 - Apr 26

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6328c1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/10d352cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AmeriStay Inn

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

St. Joseph

5.4/10

(724 reviews)

"Always friendly staff and clean quiet rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacob

$71 nightly

$82 total

May 3 - May 4

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/d7bb37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/8fa6ae99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/eb107eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Saint Joseph, MO

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

St. Joseph

4.6/10

(1,002 reviews)

"Staff was very nice, very clean, pet friendly. Will definitely stay here again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

$65 nightly

$75 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Clarksdale Hotel Reviews

![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e_y.jpg)

### Stoney Creek Hotel St. Joseph

10/10 Excellent

"The room we had had a jacuzzi tub and plenty of room. I loved that there was everything we needed and very comfortable. The front staff was very nice, helpful, and quick to check in. The breakfast was hot, delicious and a wonderful variety of food for all. "

[](https://expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b_y.jpg)

### SureStay Hotel by Best Western Cameron

2/10 Terrible

"So bad we actually left the property and drove an additional two hours to find a decent property! Lobby reeked of weed, staff were questionable, ac was not working, water wouldn’t turn off, heard something scurrying away when I opened the door, the room had a terrible smell and was very humid, they say no pets allowed but there was a large dog barking constantly 2 doors down. Overall just a disgusting room and I did not feel safe."

[](https://expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218_y.jpg)

### Drury Inn & Suites St Joseph

8/10 Good

"Clean room, staff accommodating. My only complaint would be the free breakfast. I’m a celiac and can’t eat food most anywhere I go but I can have fruit or look forward to oatmeal. Unfortunately whomever had made the oatmeal put too much water in with the oats and it looked like a loose gruel. Very unappealing. "

[](https://expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Home2 Suites By Hilton St. Joseph](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6_y.jpg)

### Home2 Suites By Hilton St. Joseph

10/10 Excellent

"Clean Room, Great Parking, Pro-Staff"

[](https://expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg)

### Red Roof Inn Cameron

10/10 Excellent

"Very clean & friendly staff !"

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![AmeriStay Inn](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430_y.jpg)

### AmeriStay Inn

2/10 Terrible

"The room was musty smelling. Toilet was not cleaned, room was dirty, TV Remote did not work. Property was not maintained well at all inside and out."

[](https://expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Motel 6 Saint Joseph, MO](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7_y.jpg)

### Motel 6 Saint Joseph, MO

2/10 Terrible

"My room didn’t have toilet paper or a holder, no towels of any kind, a foul smell, I didn’t trust the bed was actually clean from the stains and paw prints on the bed. I slept in the truck. Crossed my fingers for hot water to at least rinse off and no. None. Luke warm water no towels…. I learned my lesson. Don’t make the same mistake and pick the cheap one. "

[](https://expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg)

### Hampton Inn St. Joseph

8/10 Good

"Carpet not cleaned"

[](https://expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Quality Inn Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016_y.jpg)

### Quality Inn Cameron

4/10 Poor

"Property is old and run down. Room looked out on I-35 and corresponding noise. Ice buck was dirty. Food at breakfast was good and staff person there tried her best to keep up but there was a leak in the ceiling in the middle of the room that required a bucket. Coffee was horrible.., just coffee colored water. "

[](https://expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

## More cheap stays in Clarksdale

![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### SureStay Hotel by Best Western Cameron

2210 US Highway 36 Cameron MO

$70 nightly

$77 total

Apr 13 - Apr 14

Total with taxes and fees

8.2/10 Very Good! (1,004 reviews)

[](https://expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![AmeriStay Inn](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO

$71 nightly

$82 total

May 3 - May 4

Total with taxes and fees

5.4/10 (724 reviews)

[](https://expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Roof Inn Cameron

501 Northland Drive Cameron MO

$80 nightly

$89 total

Apr 12 - Apr 13

Total with taxes and fees

8.8/10 Excellent! (1,007 reviews)

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph MO

$83 nightly

$96 total

Apr 19 - Apr 20

Total with taxes and fees

8.2/10 Very Good! (676 reviews)

[](https://expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### My Place Hotel St Joseph MO

3621 N Village Dr St. Joseph MO

$88 nightly

$102 total

Apr 26 - Apr 27

Total with taxes and fees

9.2/10 Wonderful! (245 reviews)

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

3600 N. Village Dr. St. Joseph MO

$114 nightly

$132 total

Apr 12 - Apr 13

Total with taxes and fees

9.2/10 Wonderful! (814 reviews)

[](https://expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

## Hotels in Clarksdale with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

6 properties

[](https://expedia.com/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

27 properties

[](https://expedia.com/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Clarksdale?

> This central area is the heart of Clarksdale's blues music scene and is very walkable. You'll find a high concentration of blues clubs, juke joints, and historic markers. The Delta Blues Museum is also located downtown, offering a deep dive into the region's musical heritage. Many of the city's unique restaurants and shops are clustered here, making it convenient for exploring on foot.
> 
>   
> Solo travelers and couples often find this area ideal due to its lively evenings and the ease of accessing various entertainment options.

### When is the best time to go to Clarksdale?

> Spring brings mild temperatures, typically ranging from the 60s to 70s Fahrenheit, with blooming wildflowers and lush greenery. It's an excellent time for couples who enjoy outdoor activities like hiking or picnicking in nearby parks without the intense summer heat. The comfortable climate makes strolling through the small town center enjoyable.
> 
>   
> Fall also provides agreeable temperatures, usually in the 60s, along with the scenic beauty of changing leaves. This period is ideal for solo travelers or those seeking a quiet retreat. The cooler weather is superb for visiting local antique shops, exploring historical sites, or simply enjoying a warm drink at a local coffee shop.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Clarksdale hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Clarksdale hotel?

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