Title: Top 10 Hotels in Clarksdale, MO from $66 - Competitive Prices | Expedia.com

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## Go beyond your typical stay in Clarksdale

Pool

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=POOL)

Pet-friendly

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=PETS)

Great for families

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.com/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America&regionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=APARTMENT)

## Check prices for these dates

Tonight

[Feb 26 - Feb 27](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634983445286&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Clarksdale hotels

![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f4c6728d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/e03c581b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vineyard Mansion & Carriage House Bed & Breakfast

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

St. Joseph

9.0/10

Wonderful

(200 reviews)

"Enjoyed our stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vincent

$147 nightly

$157 total

Feb 28 - Mar 1

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### My Place Hotel St Joseph MO

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(220 reviews)

"It was a clean place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ayden

$74 nightly

$85 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, Ensuite (Single Queen ) | Bathroom | Combined shower/tub, hair dryer, towels, soap](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/c9cd0093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Whiskey Mansion

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(589 reviews)

"Bueatiful home, clean, quiet and fantastic service and food!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ellie

$148 nightly

$172 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6685816e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/10d352cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6328c1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AmeriStay Inn

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

St. Joseph

5.4/10

(705 reviews)

"Always friendly staff and clean quiet rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacob

$71 nightly

$82 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(102 reviews)

"Great stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marcella M

$106 nightly

$122 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/71deeec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/d40daa76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(809 reviews)

"Breakfast was good, nice selection of food, Front desk staff were courteous and helpful, cleaning ladies were helpful, room was adequate, nice location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kim

$95 nightly

$110 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/923f99c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/d2e48a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

St. Joseph

8.2/10

Very Good

(668 reviews)

"A great place to stay-clean and friendly staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

$79 nightly

$92 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/e0d9868d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

St. Joseph

9.6/10

Exceptional

(479 reviews)

"Clean room and friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

$96 nightly

$112 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/8fa6ae99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/f99f9ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/d7bb37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Saint Joseph, MO

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

St. Joseph

4.6/10

(1,000 reviews)

"Staff was very nice, very clean, pet friendly. Will definitely stay here again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

$70 nightly

$81 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Theme Suite with Whirlpool | Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stoney Creek Hotel St. Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

St. Joseph

9.2/10

Wonderful

(1,603 reviews)

"Always enjoy staying here . Staff was awesome 👍"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

evvamae

$124 nightly

$143 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/cdd2480a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/9fa0a9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/eea04022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information)

Cameron

7.6/10

Good

(842 reviews)

"Easy to locate, quiet, room was clean, breakfast was OK"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vicki

$67 nightly

$74 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/dc26a342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

Cameron

8.8/10

Excellent

(1,001 reviews)

"Clean room and friendly staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica

$79 nightly

$87 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/60106125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Hotel by Best Western Cameron

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

Cameron

8.2/10

Very Good

(1,000 reviews)

"Good one night stay experience "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

LIQIANG

$70 nightly

$77 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Accessible (Sofa Sleeper, Roll-in Shower, 2 Rooms) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites St Joseph

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

St. Joseph

9.4/10

Exceptional

(1,001 reviews)

"Amazing friendly staff, clean rooms, bathroom was spotless. Enjoyed my stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron

$100 nightly

$116 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/28b1385b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

Cameron

8.4/10

Very Good

(634 reviews)

"Surprisingly quite next to the interstate. Older hotel, but still has some charm. Breakfast, customer service and the rooms were nice. My family and I enjoyed our stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

$106 nightly

$118 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

![Room, 1 King Bed, Hot Tub | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/d3b97e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/3d5ca308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

Cameron

8.4/10

Very Good

(645 reviews)

"Very clean and friendly staff. Nice place!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dean

$77 nightly

$84 total

Mar 6 - Mar 7

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Smoking, Ground Floor | Free cribs/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Cameron

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

Cameron

6.2/10

(162 reviews)

"Lovely staff. Very helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Colleen

$68 nightly

$75 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/d807d6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free valet parking](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/abdbbdba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/132d826f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/c67791cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Capri Motel By OYO Elwood, Wathena

[](https://www.expedia.com/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information)

Wathena

$75 nightly

$81 total

Feb 28 - Mar 1

Total with taxes and fees

[](https://www.expedia.com/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/c6efac2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/96bdd18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/873f6f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3cfc730e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Cameron, MO

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

Cameron

7.0/10

Good

(295 reviews)

"Very clean and comfortable. Great staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joseph

$59 nightly

$66 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information)

![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/w4032h2718x0y306-05e60f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | In-room dining](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/9ed1ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f2b04a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cameron Suites

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

Cameron

$201 nightly

$220 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Clarksdale Hotel Reviews

![Home2 Suites By Hilton St. Joseph](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635_y.jpg)

### Home2 Suites By Hilton St. Joseph

10/10 Excellent

"Everything is always perfect when we stay here. Always clean! The room is perfect it’s really like home away. "

[](https://expedia.com/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information)

![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29_y.jpg)

### Drury Inn & Suites St Joseph

10/10 Excellent

"Excellent room. Wonderful staff"

[](https://expedia.com/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information)

![Super 8 by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4_y.jpg)

### Super 8 by Wyndham Cameron

10/10 Excellent

"Staff was really nice and friendly."

[](https://expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg)

### My Place Hotel St Joseph MO

10/10 Excellent

"Very nice hotel, clean and efficient staff."

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/342fa799_y.jpg)

### Stoney Creek Hotel St. Joseph

10/10 Excellent

"Always enjoy staying here . Staff was awesome 👍"

[](https://expedia.com/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information)

![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79_y.jpg)

### Fairfield Inn & Suites by Marriott St. Joseph

10/10 Excellent

"As great"

[](https://expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

![Whiskey Mansion](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103_y.jpg)

### Whiskey Mansion

10/10 Excellent

"Holly was a wonderful host for our stay!! Breakfasts felt so fancy and made with love, definitely coming back again! The decor and vibe of the place was so beautiful :)"

[](https://expedia.com/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information)

![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent

"Very nice rooms. Friendly check in. Generous free breakfast. "

[](https://expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Quality Inn Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/5baaa282_y.jpg)

### Quality Inn Cameron

10/10 Excellent

"Yes"

[](https://expedia.com/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information)

## More cheap stays in Clarksdale

![Days Inn by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Cameron

601 E. Bryan Road Cameron MO

$67 nightly

$74 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://expedia.com/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information)

![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### My Place Hotel St Joseph MO

3621 N Village Dr St. Joseph MO

$74 nightly

$85 total

Mar 8 - Mar 9

Total with taxes and fees

9.2/10 Wonderful! (220 reviews)

[](https://expedia.com/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information)

![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Roof Inn Cameron

501 Northland Drive Cameron MO

$79 nightly

$87 total

Feb 27 - Feb 28

Total with taxes and fees

8.8/10 Excellent! (1,001 reviews)

[](https://expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information)

![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph MO

$79 nightly

$92 total

Mar 8 - Mar 9

Total with taxes and fees

8.2/10 Very Good! (668 reviews)

[](https://expedia.com/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information)

![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express Hotel & Suites St. Joseph by IHG

3600 N. Village Dr. St. Joseph MO

$95 nightly

$110 total

Mar 1 - Mar 2

Total with taxes and fees

9.2/10 Wonderful! (809 reviews)

[](https://expedia.com/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information)

![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott St. Joseph

4779 Tuscany Drive St. Joseph MO

$96 nightly

$112 total

Mar 8 - Mar 9

Total with taxes and fees

9.6/10 Exceptional! (479 reviews)

[](https://expedia.com/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information)

## Hotels in Clarksdale with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

6 properties

[](https://expedia.com/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

27 properties

[](https://expedia.com/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Clarksdale?

> This central area is the heart of Clarksdale's blues music scene and is very walkable. You'll find a high concentration of blues clubs, juke joints, and historic markers. The Delta Blues Museum is also located downtown, offering a deep dive into the region's musical heritage. Many of the city's unique restaurants and shops are clustered here, making it convenient for exploring on foot.
> 
>   
> Solo travelers and couples often find this area ideal due to its lively evenings and the ease of accessing various entertainment options.

### When is the best time to go to Clarksdale?

> Spring brings mild temperatures, typically ranging from the 60s to 70s Fahrenheit, with blooming wildflowers and lush greenery. It's an excellent time for couples who enjoy outdoor activities like hiking or picnicking in nearby parks without the intense summer heat. The comfortable climate makes strolling through the small town center enjoyable.
> 
>   
> Fall also provides agreeable temperatures, usually in the 60s, along with the scenic beauty of changing leaves. This period is ideal for solo travelers or those seeking a quiet retreat. The cooler weather is superb for visiting local antique shops, exploring historical sites, or simply enjoying a warm drink at a local coffee shop.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Clarksdale hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Clarksdale hotel?

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