Top 10 Hotels in Clarksdale, MO (from $69) 2026 - Competitive Prices

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Our top choices for Clarksdale hotels

An indoor swimming pool with clear glass walls, a tiled floor, and overhead lighting.

A neatly made bed with white linens and a headboard.

A Hampton Inn by Hilton building with a modern facade, large windows, and a well-lit entrance.

A snack and beverage vending area with various snack options and refrigerated beverage dispensers.

1. Hampton Inn St. Joseph

St. Joseph

Gary

$80 nightly

$92 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.

A pool area with a rock formation backdrop, a wooden post, and a sign indicating a clinic.

A wooden reception desk with a moose mural, a mounted cow head, and a framed map on the wall.

A cozy log cabin interior with a fireplace, wooden furniture, and a television.

2. Stoney Creek Hotel St. Joseph

St. Joseph

Eduardo

$106 nightly

$123 total

Oct 29 - Oct 30

Total with taxes and fees

A lobby with a seating area, a reception desk, and a chandelier.

A hotel lobby with a reception desk, seating area, and a refrigerator.

A Drury Inn & Suites hotel with a modern architectural design, featuring a covered entrance and a parking lot.

A hotel room with a kitchenette, a sofa, a bench, a lamp, and a framed picture on the wall.

3. Drury Inn & Suites St Joseph

St. Joseph

Harriet

$110 nightly

$127 total

Nov 1 - Nov 2

Total with taxes and fees

A Holiday Inn Express & Suites hotel with a covered entrance and a stone facade.

A hotel room with a bed, a desk, a microwave, a sofa, and a chair.

A swimming pool with a clear blue water surface, surrounded by wooden lounge chairs and a tiled deck.

A hotel lobby with a green sofa, yellow armchairs, a patterned carpet, and a reception desk.

4. Holiday Inn Express Hotel & Suites St. Joseph by IHG

St. Joseph

Teresa

$111 nightly

$128 total

Nov 23 - Nov 24

Total with taxes and fees

A modern living room with a blue sofa, a fireplace, and a stone accent wall.

A Fairfield Inn & Suites Marriott hotel entrance with a modern design, including a prominent overhang and a stone pillar.

An indoor swimming pool with clear water, a lifeguard chair, and a pool ladder.

A modern hotel lobby with a stone fireplace, blue sofas, a round table, and large windows offering a view of the parking lot.

5. Fairfield Inn & Suites by Marriott St. Joseph

St. Joseph

Chris

$105 nightly

$122 total

Nov 1 - Nov 2

Total with taxes and fees

A multi-story hotel with a prominent sign for Woodspring Suites.

A compact room with a bed, kitchenette, TV, and a wardrobe.

A modern kitchen with a wooden table, white chairs, and a blue accent wall.

A hotel sign for WoodSpring Suites with a clear view of the building in the background.

6. Woodspring Suites St. Joseph

St. Joseph

Robert

$94 nightly

$109 total

Oct 26 - Oct 27

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a kitchenette, and a framed picture on the wall.

A multi-story hotel with a 'My Place' sign, featuring a stone facade and a covered entrance.

A modern restaurant with a bar area, seating arrangements, and a kitchen in the background.

7. My Place Hotel St Joseph MO

St. Joseph

Jeanne

$83 nightly

$96 total

Nov 22 - Nov 23

Total with taxes and fees

A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.

A two-story building with a covered parking area and a brick facade.

An indoor swimming pool with clear water, surrounded by white plastic chairs and tables, and a lifeguard sign on the wall.

A reception area with a marble counter, a fish tank, a welcome sign, and a 'Super 8' sign.

8. Super 8 by Wyndham Cameron

Cameron

richard

$89 nightly

$98 total

Nov 20 - Nov 21

Total with taxes and fees

A kitchen with wooden cabinets, a toaster, a fruit bowl, and a waffle maker.

A hotel room with a bed, a desk, a chair, a television, and a bathroom.

A hotel room with a bed, a desk, a chair, a television, and an air conditioning unit.

A RedRoof Inn building with a flat facade, multiple windows, and a covered entrance.

9. Red Roof Inn Cameron

Cameron

Bret

$91 nightly

$101 total

Nov 1 - Nov 2

Total with taxes and fees

A swimming pool with a hot tub, a ladder, and a slide.

A reception area with a reception desk, a plant, a coffee station, and a sign for breakfast.

A hotel room with a large bed, two bedside tables with lamps, a desk, and a chair.

A reception area with a coffee station, a potted plant, and a banner promoting breakfast.

10. Quality Inn Cameron

Cameron

Barbara

$106 nightly

$118 total

Nov 24 - Nov 25

Total with taxes and fees

A living room with two sofas, a coffee table, a lamp, and a potted plant.

An indoor swimming pool with clear blue water, surrounded by white lounge chairs and a wooden ceiling.

A hotel room with a large bed, a desk, a television, and a window with curtains.

A reception area with a Days Inn sign, a wooden bench, a small table, and a potted plant.

11. Days Inn by Wyndham Cameron

Cameron

Catherine Louise

$71 nightly

$78 total

Nov 2 - Nov 3

Total with taxes and fees

An outdoor seating area with a fire feature, a pool, and a view of the building.

A modern hotel reception desk with a wooden finish, a 'HOME 2' sign above, and a blue 'Hilton Honors' sign on the counter.

A multi-story hotel with a prominent 'HOME 2' sign, outdoor seating area, and a covered entrance.

A hotel room with two beds, a desk, a TV, and a view of the outdoors.

12. Home2 Suites By Hilton St. Joseph

St. Joseph

Lindsey

$135 nightly

$156 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a desk, a chair, and a television.

A vending machine with snacks and a 7UP machine in a hallway with a staircase.

A building with a 'welcome' sign, a number '6' on the door, and a covered entrance area.

A hotel reception area with a wooden counter, a coffee machine, a phone, and a television.

13. Motel 6 Saint Joseph, MO

St. Joseph

Picaso

$60 nightly

$69 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with a large bed, a red wall, and a cityscape painting above the bed.

A hotel room with a television, a lamp, a microwave, and a desk with a chair.

A reception desk with a clock, decorative wall art, and American flags.

A restaurant with green tables and red chairs, a counter with a coffee machine, and a painting on the wall.

14. AmeriStay Inn

St. Joseph

Jennifer

$75 nightly

$87 total

Oct 27 - Oct 28

Total with taxes and fees

A large, historic brick building with a prominent tower and a grand entrance.

A traditional interior with a fireplace, wooden furniture, and a chandelier.

A traditional room with a fireplace, ornate chandelier, and classic furniture.

A grand room with a red patterned carpet, a large potted plant, a wooden staircase, and a chandelier.

15. Vineyard Mansion & Carriage House Bed & Breakfast

St. Joseph

Keith

$147 nightly

$157 total

Oct 26 - Oct 27

Total with taxes and fees

A large brick building with multiple windows and a covered porch area.

A grand entrance with a stained glass window, a red upholstered sofa, and a wooden chair.

A red brick building with a garden in front.

A traditional interior with a fireplace, a wooden staircase, and a patterned floor.

16. Whiskey Mansion

St. Joseph

Lana

$136 nightly

$157 total

Oct 28 - Oct 29

Total with taxes and fees

A balcony with a stainless steel refrigerator, a wicker chair, and an air conditioning unit.

A building with a covered entrance, a small patio with chairs, and a window with blinds.

A cluttered office space with a desk, computer, printer, and various office supplies.

A motel with a large sign, a parking lot, and a building with a sloped roof.

17. Capri Motel By OYO Elwood, Wathena

Wathena

Glen

$83 nightly

$90 total

Oct 31 - Nov 1

Total with taxes and fees

A hotel room with two beds, a nightstand with a lamp, a small table, a mirror, and a window.

A living room with a leather sofa, a glass coffee table, and various potted plants.

A hotel room with a wooden desk, two red chairs, a TV mounted on the wall, a mirror, and a wardrobe.

A lobby with a fireplace, a table with four chairs, and a patterned carpet.

18. Econo Lodge Cameron

Cameron

Barbara

$78 nightly

$85 total

Nov 24 - Nov 25

Total with taxes and fees

A reception desk with a "WELCOME" sign, a clock, and a mirror.

A compact refrigerator with a microwave on top, an air conditioner, and a power outlet on the wall.

A hotel room with two beds, a desk with a chair, a microwave, a TV, and a small shelf with toiletries.

A kitchenette with a coffee machine, a trash can, and a sign indicating coffee service hours.

19. Motel 6 Cameron, MO

Cameron

Mark

$75 nightly

$82 total

Oct 26 - Oct 27

Total with taxes and fees

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Top Clarksdale Hotel Reviews

My Place Hotel St Joseph MO

10/10 Excellent

"Everything was great. The room was clean and stocked with plenty of towels. Had an extra blanket on the bed. Staff was friendly and answered all my questions. Property sits far enough from the main roads that there was very low traffic noise."

Stoney Creek Hotel St. Joseph

10/10 Excellent

"The staff were super helpful"

Home2 Suites By Hilton St. Joseph

10/10 Excellent

"It was a great hotel"

Drury Inn & Suites St Joseph

10/10 Excellent

"Drury’s inns have great reputations and they are well deserved. Totally top of its class!"

Vineyard Mansion & Carriage House Bed & Breakfast

10/10 Excellent

"This b&b is indeed a mansion, and a true Victorian beauty, lovingly restored and fully furnished with beautiful antiques and art. Our room was gorgeous, very spacious and extremely comfortable; we wish we could have stayed longer! Our host was extremely helpful and gracious, and we appreciated the variety of food on offer for breakfast and snacks. We will certainly make a point of staying there again should we return to the area, and we highly recommend this property to anyone who appreciates historic homes."

Woodspring Suites St. Joseph

8/10 Good

"Clean, quiet, comfortable Full kitchen, but no dishes, utensils, hand towels, etc Few amenities, no breakfast only coffee, no hairdryer"

SureStay Hotel by Best Western Cameron

10/10 Excellent

"Great stay and pets stay free. Also the property was really cool"

Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent

"Best hotel in a 2-week trip. Friendly staff. Ultra clean. Great view. Extremely comfortable and clean furniture. Other hotels should pay attention."

Red Roof Inn Cameron

10/10 Excellent

"Check in was nice and the hotel was very clean. Coffee was instant but still okay. Appreciate having a dog friendly room"

More cheap stays in Clarksdale

AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO

$75 nightly

$87 total

Oct 27 - Oct 28

Total with taxes and fees