Top 10 Hotels in Clarksdale, MO (from $69) 2026 - Competitive Prices

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Our top choices for Clarksdale hotels

An indoor swimming pool with clear glass walls, a tiled floor, and overhead lighting.

A reception desk with a clock, a framed picture, and a wall with a 'smile' sign.

A neatly made bed with white linens and a headboard.

A snack and beverage vending area with various snack options and refrigerated beverage dispensers.

1. Hampton Inn St. Joseph

St. Joseph

Gary

$80 nightly

$92 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel lobby with a green sofa, yellow armchairs, a patterned carpet, and a reception desk.

A building with a sign for Holiday Inn Express & Suites.

A breakfast bar with a variety of food options including cereal, fruit, yogurt, eggs, and milk.

A swimming pool with a clear blue water surface, surrounded by wooden lounge chairs and a tiled deck.

2. Holiday Inn Express Hotel & Suites St. Joseph by IHG

St. Joseph

Teresa

$107 nightly

$124 total

Nov 22 - Nov 23

Total with taxes and fees

A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.

A wooden reception desk with a moose mural, a mounted cow head, and a framed map on the wall.

A pool area with a rock formation backdrop, a wooden post, and a sign indicating a clinic.

A cozy log cabin interior with a fireplace, wooden furniture, and a television.

3. Stoney Creek Hotel St. Joseph

St. Joseph

Barbara

$105 nightly

$122 total

Oct 25 - Oct 26

Total with taxes and fees

A lobby with a seating area, a reception desk, and a chandelier.

A Drury Inn & Suites hotel with a modern architectural design, featuring a covered entrance and a parking lot.

A hotel room with a kitchenette, a sofa, a bench, a lamp, and a framed picture on the wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

4. Drury Inn & Suites St Joseph

St. Joseph

Harriet

$110 nightly

$127 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.

An indoor swimming pool with clear water, surrounded by white plastic chairs and tables, and a lifeguard sign on the wall.

A reception area with a marble counter, a fish tank, a welcome sign, and a 'Super 8' sign.

A two-story building with a covered parking area and a brick facade.

5. Super 8 by Wyndham Cameron

Cameron

richard

$88 nightly

$97 total

Oct 31 - Nov 1

Total with taxes and fees

A multi-story hotel with a flat roof, a central entrance, and a parking lot in front.

A hotel room with a bed, a desk with a TV, a chair, and a window with curtains.

A compact kitchen with a built-in microwave, a refrigerator, and a sink.

A laundry room with a row of stacked washing machines, a wooden door, and a bench.

6. Woodspring Suites St. Joseph

St. Joseph

Robert

$94 nightly

$109 total

Oct 25 - Oct 26

Total with taxes and fees

A modern living room with a blue sofa, a fireplace, and a stone accent wall.

A Fairfield Inn & Suites Marriott hotel entrance with a modern design, including a prominent overhang and a stone pillar.

A modern hotel lobby with a stone fireplace, blue sofas, a round table, and large windows offering a view of the parking lot.

A restaurant with a long wooden table, chairs, and a bar area.

7. Fairfield Inn & Suites by Marriott St. Joseph

St. Joseph

Chris

$105 nightly

$122 total

Nov 1 - Nov 2

Total with taxes and fees

A modern restaurant with a bar area, seating arrangements, and a kitchen in the background.

A multi-story hotel with a 'My Place' sign, featuring a stone facade and a covered entrance.

8. My Place Hotel St Joseph MO

St. Joseph

Jeanne

$83 nightly

$96 total

Nov 22 - Nov 23

Total with taxes and fees

A compact kitchen with wooden cabinets, a dining table with chairs, and a coffee machine.

A hotel room with a bed, a desk, a microwave, a telephone, and a wall-mounted lamp.

A hotel room with a bed, a desk, a chair, a television, and an air conditioning unit.

A Red Roof Inn with a two-story building, multiple windows, and a fenced outdoor area.

9. Red Roof Inn Cameron

Cameron

Bret

$91 nightly

$101 total

Nov 1 - Nov 2

Total with taxes and fees

A swimming pool with a hot tub, a ladder, and a slide.

A hotel room with a brown sofa, a wooden coffee table, a desk with a chair, and a lamp. There are three framed pictures on the wall, a window with curtains, and a radiator.

A reception area with a coffee station, a potted plant, and a banner promoting breakfast.

A hotel room with a large bed, two bedside tables with lamps, a desk, and a chair.

10. Quality Inn Cameron

Cameron

Barbara

$106 nightly

$117 total

Nov 24 - Nov 25

Total with taxes and fees

A living room with two sofas, a coffee table, a lamp, and a potted plant.

A hotel with a covered outdoor seating area, a clock tower, and a well-lit facade.

A hotel room with a large bed, a desk, a television, and a window with curtains.

A reception area with a Days Inn sign, a wooden bench, a small table, and a potted plant.

11. Days Inn by Wyndham Cameron

Cameron

Catherine Louise

$71 nightly

$78 total

Nov 1 - Nov 2

Total with taxes and fees

An outdoor patio with tables and chairs, string lights, and a view of the landscape.

A hotel room with a sofa, two beds, a patterned ottoman, a wall art piece, and a window with a view.

A gym with exercise equipment including treadmills, a bench, and a weightlifting station.

A compact hotel room with a kitchenette, a dining area, and a TV.

12. Home2 Suites By Hilton St. Joseph

St. Joseph

Lindsey

$135 nightly

$156 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a large bed, a red wall, and a cityscape painting above the bed.

A restaurant with green tables and red chairs, a counter with a coffee machine, and a painting on the wall.

A hotel room with a television, a lamp, a microwave, and a desk with a chair.

A reception desk with a clock, decorative wall art, and American flags.

13. AmeriStay Inn

St. Joseph

Jennifer

$73 nightly

$84 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with two beds, a desk, a chair, and a television.

A vending machine with snacks and a 7UP machine in a hallway with a staircase.

A hotel reception area with a wooden counter, a coffee machine, a phone, and a television.

A hallway with a 7UP vending machine, white doors, and a brown mat.

14. Motel 6 Saint Joseph, MO

St. Joseph

Picaso

$60 nightly

$69 total

Nov 8 - Nov 9

Total with taxes and fees

A large, historic brick building with a prominent tower and a grand entrance.

A brick building with a covered porch and a large bush of white flowers.

A traditional interior with a fireplace, wooden furniture, and a chandelier.

A grand room with a red patterned carpet, a large potted plant, a wooden staircase, and a chandelier.

15. Vineyard Mansion & Carriage House Bed & Breakfast

St. Joseph

Keith

$147 nightly

$157 total

Oct 25 - Oct 26

Total with taxes and fees

A balcony with a stainless steel refrigerator, a wicker chair, and an air conditioning unit.

A motel with a large sign, a parking lot, and a building with a sloped roof.

A cluttered office space with a desk, computer, printer, and various office supplies.

A building with a covered entrance, a small patio with chairs, and a window with blinds.

16. Capri Motel By OYO Elwood, Wathena

Wathena

Glen

$83 nightly

$90 total

Oct 31 - Nov 1

Total with taxes and fees

A large brick building with multiple windows and a covered porch area.

A grand entrance with a stained glass window, a red upholstered sofa, and a wooden chair.

A traditional interior with a fireplace, a wooden staircase, and a patterned floor.

A red brick building with a garden in front.

17. Whiskey Mansion

St. Joseph

Lana

$134 nightly

$155 total

Nov 24 - Nov 25

Total with taxes and fees

A hotel room with two beds, a nightstand with a lamp, a small table, a mirror, and a window.

A gazebo with a metal roof and wooden benches.

A hotel room with a wooden desk, two red chairs, a TV mounted on the wall, a mirror, and a wardrobe.

A living room with a leather sofa, a glass coffee table, and various potted plants.

18. Econo Lodge Cameron

Cameron

Barbara

$77 nightly

$85 total

Nov 24 - Nov 25

Total with taxes and fees

A reception desk with a "WELCOME" sign, a clock, and a mirror.

A hotel room with two beds, a desk with a chair, a microwave, a TV, and a small shelf with toiletries.

A kitchenette with a coffee machine, a trash can, and a sign indicating coffee service hours.

A compact kitchenette with a microwave, sink, and small refrigerator.

19. Motel 6 Cameron, MO

Cameron

Mark

$75 nightly

$82 total

Oct 25 - Oct 26

Total with taxes and fees

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Top Clarksdale Hotel Reviews

Woodspring Suites St. Joseph

8/10 Good

"Clean, quiet, comfortable Full kitchen, but no dishes, utensils, hand towels, etc Few amenities, no breakfast only coffee, no hairdryer"

My Place Hotel St Joseph MO

10/10 Excellent

"Great trip."

SureStay Hotel by Best Western Cameron

10/10 Excellent

"Great stay and pets stay free. Also the property was really cool"

Holiday Inn Express Hotel & Suites St. Joseph by IHG

10/10 Excellent

"Best hotel in a 2-week trip. Friendly staff. Ultra clean. Great view. Extremely comfortable and clean furniture. Other hotels should pay attention."

Red Roof Inn Cameron

10/10 Excellent

"Check in was nice and the hotel was very clean. Coffee was instant but still okay. Appreciate having a dog friendly room"

Whiskey Mansion

10/10 Excellent

"Nos gustó mucho, me volvería a quedar"

Home2 Suites By Hilton St. Joseph

10/10 Excellent

"👍"

Vineyard Mansion & Carriage House Bed & Breakfast

10/10 Excellent

"Wonderful and charming place to stay"

Motel 6 Saint Joseph, MO

8/10 Good

"Great road side stray for a night. Slept great."

More cheap stays in Clarksdale

AmeriStay Inn

4502 SE US HWY 169 St. Joseph MO

$73 nightly

$84 total

Oct 25 - Oct 26

Total with taxes and fees