Plan your trip

A curved road alongside a body of water with a stone embankment, surrounded by trees with autumn foliage.

Find all hotels by Motel 6 in St. Joseph, MO from $69

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices

    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

  • Check prices for these dates

    Check prices for these dates, December 12 – 13, 2026

    View in a map

    Our top choices for St. Joseph Motel 6

    1. Motel 6 Percival, IA

    A hotel room with a large bed, two single beds, a desk, a chair, a TV, and a heater.

    2. Motel 6 Saint Joseph, MO

    A hotel room with two beds, a desk, a chair, and a television.

    3. Motel 6 Cameron, MO

    A reception desk with a "WELCOME" sign, a clock, and a mirror.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

    View all properties

    Top St. Joseph Hotel Reviews

    Hamburg Inn & Suites

    A building with a sign reading "Hamburg Inn & Suites" and a covered outdoor seating area with tables and chairs.

    Whiskey Mansion

    A large brick building with multiple windows and a covered porch area.

    Cobblestone Inn & Suites - Maryville

    A patio with picnic tables and a grassy field.

    My Place Hotel St Joseph MO

    Private kitchen

    Holiday Inn Express Hotel & Suites St. Joseph by IHG

    A buffet with various food items, including omelets and other dishes, served in metal containers.

    Lied Lodge & Conference Center

    An outdoor patio with wooden tables and chairs, a curved stone wall, and a view of the sunset.

    Cobblestone Inn & Suites - Clarinda

    A spacious lobby with a fireplace, seating area, and a television mounted on the wall.

    Cobblestone Inn & Suites - Lamoni

    A living room with a stone wall, a fireplace, a flat-screen TV, and two patterned armchairs.

    Holiday Inn Express & Suites Kearney by IHG

    A Holiday Inn Express & Suites building with a covered entrance, stone pillars, and a fire lane.

    Shenandoah Inn & Suites

    A reception desk at Shenandoah Inn & Suites with a wooden panel design, a sign above the desk, and various items on the counter.

    Vineyard Mansion & Carriage House Bed & Breakfast

    A large, historic brick building with a prominent tower and a grand entrance.

    Explore a world of travel with Expedia