Clarkson Valley Vacation Rentals

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Our top choices for Clarkson Valley vacation rentals

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
$123 nightly
The price is $144
Jan 4 - Jan 5, 2026
Total with taxes and fees
White House at Grand Central

The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles Historic District
10.0 out of 10, Exceptional, (136)
"We loved staying here in this adorable clean house that was only 1 block off of downtown Main Street shopping. "
United States
Lisa S.
The St. Charles Guest House, lovely historic home, fun for families and groups

Value Suites Extended Stay - St Louis

Value Suites Extended Stay - St Louis
3.0 star property
Maryland Heights
7.0 out of 10, Good, (1110)
"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."
United States
Timothy
$453 nightly
The price is $525
Dec 13 - Dec 14
Total with taxes and fees
Value Suites Extended Stay - St Louis

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (160)
"Very clean, check in was easy, great neighborhood with lots of food close. "
United States
Laura H.
$132 nightly
The price is $134
Dec 14 - Dec 15
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (102)
"Check-in was easy and the house was lovely "
United States
Delfino A.
$314 nightly
The price is $320
Dec 23 - Dec 24
Total with taxes and fees
Stunning 1890's Home - Sleeps 8!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
St. Charles Historic District
10.0 out of 10, Exceptional, (211)
"Nice view of the Mississippi in the morning. Just off of the main street in old town St Charles, this place was perfect for our needs."
United States
Ralph
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

Cozy Clark Suite in Frenchtown Saint Charles

Cozy Clark Suite in Frenchtown Saint Charles
St. Charles Historic District
9.6 out of 10, Exceptional, (14)
"Awesome place to stay"
United States
paul
Cozy Clark Suite in Frenchtown Saint Charles

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (134)
"We will be back. Nice quiet stay. "
United States
Kathe H.
$251 nightly
The price is $251
Dec 15 - Dec 16
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

Honky Tonk Hideaway

Honky Tonk Hideaway
St. Charles Historic District
8.8 out of 10, Excellent, (12)
"Great location close to historic district."
United States
Hugh S.
$308 nightly
The price is $316
Dec 25 - Dec 26
Total with taxes and fees
Honky Tonk Hideaway

Home Near Main Street-Covered Patio-Hot Tub!

Home Near Main Street-Covered Patio-Hot Tub!
Saint Charles
9.8 out of 10, Exceptional, (26)
"The place was great! "
United States
Melissa I.
$443 nightly
The price is $452
Dec 15 - Dec 16
Total with taxes and fees
Home Near Main Street-Covered Patio-Hot Tub!

Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St
St. Charles Historic District
8.6 out of 10, Excellent, (14)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
$209 nightly
The price is $235
Dec 14 - Dec 15
Total with taxes and fees
Madison House 1 -Walk to Main St

Tamm Ave 3-BR Retreat

Tamm Ave 3-BR Retreat
Dogtown
9.6 out of 10, Exceptional, (48)
"We enjoyed are stay at this house. It was very clean and comfortable. Host was very quick to respond and easy check in. Nice neighborhood, felt very safe. Would for sure stay here again!!"
United States
Cindy A.
Tamm Ave 3-BR Retreat

StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.

StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.
Southwest Garden
10.0 out of 10, Exceptional, (288)
"A comfortable stay in a wonderful neighborhood. This location was great and allowed us to visit all the places we planned. It was very clean and well stocked "
United States
Karen F.
$145 nightly
The price is $159
Dec 14 - Dec 15
Total with taxes and fees
StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.

Residence on the Roundabout

Residence on the Roundabout
St Charles
9.4 out of 10, Exceptional, (144)
"House was very nice. Pictures were good and we knew what to expect. Location was great for where we wanted to go.Owner was punctual when we had any questions!"
United States
Anne L.
Residence on the Roundabout

Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (136)
"Very cute property in historic neighborhood. We enjoyed our stay!"
United States
Jo L.
$143 nightly
The price is $168
Dec 15 - Dec 16
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (31)
"House and yard were great! Loved the location."
United States
Jennifer P.
$443 nightly
The price is $452
Dec 14 - Dec 15
Total with taxes and fees
Charming open 4bd and screen-in porch! Sleeps 10!

The Otter Suite at Divine Otter

The Otter Suite at Divine Otter
St. Charles Historic District
9.0 out of 10, Wonderful, (7)
"We absolutely loved this place! I would recommend this place. We had one issue but it was resolved. If you have children, I would probably stay somewhere else. There are bars all around and gets loud at night but it does get really quiet after 1:30 a.m. The property manager was absolutely amazing and is very quick to respond to your needs. "
United States
kim F.
The Otter Suite at Divine Otter

Spacious 2 BR Balcony Hideaway

Spacious 2 BR Balcony Hideaway
Northampton
8.0 out of 10, Very Good, (15)
"Great stay! Management was easy to reach and very helpful when we couldnt find the correct wifi network. Nice place, would stay again."
United States
Bob C.
Spacious 2 BR Balcony Hideaway

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟
St. Charles Historic District
9.8 out of 10, Exceptional, (75)
"Great location, lovely house.Easy to find restaurants, places to shop and nice area for strolling."
United States
Dianne P.
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
St. Charles Historic District
9.8 out of 10, Exceptional, (61)
"We had a great weekend and enjoyed the house very much! We had everything we needed!"
United States
Laurie S.
$412 nightly
The price is $420
Dec 14 - Dec 15
Total with taxes and fees
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clarkson Valley Hotel Reviews

Find out more about Clarkson Valley

Everything you need to know about Clarkson Valley vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Clarkson Valley vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Clarkson Valley vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Clarkson Valley vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Clarkson Valley. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Clarkson Valley in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $134 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Clarkson Valley rentals

At Expedia, we put the best Clarkson Valley vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Clarkson Valley rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Clarkson Valley vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Clarkson Valley. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Clarkson Valley?

Yes, you can find vacation rentals near the most popular local attractions in Clarkson Valley, or you can go with a secluded option if you want a relaxing place to stay. Clarkson Valley is known for its baseball games.

What are some of the best vacation rentals in Clarkson Valley?

Stunning 1890's Home - Sleeps 8! : This vacation home rental near Clarkson Valley is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What can I see and do in Clarkson Valley?

While exploring the area, visit family-friendly sights like Chesterfield Sports Fusion, or get outside and enjoy nature at Lou Fusz Soccer Complex. In the larger area, you’ll find The Factory and St. Louis Premium Outlets.

What are vacation rentals like in Clarkson Valley?

Vacation rentals are privately owned properties you can book for several days or more in Clarkson Valley. Vacation rentals provide amenities such as laundry facilities and kitchens so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from shared hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for family gatherings.