Title: Top Misiones Department Hotels: 2026 Best Hotels in Misiones Department - Expedia.com [Vacation Rentals in Misiones Department](https://expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Vacation-Rental-Destinations)[Car Rentals in Misiones Department](https://expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Car-Rental-Destinations)[Misiones Department Vacations](https://expedia.com/Misiones-Department.d553248635975177264.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - 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Explore a world of travel with Expedia ### Expedia's Latest Trends Hotels - [All-inclusive Resorts in Galápagos](https://expedia.com/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllinclusiveHotel.Hotel-Filter-Destinations) - [Santa Rosa 5 Star Hotels](https://expedia.com/5Star-Santa-Rosa-Hotels.s50-0-d3000379166.Travel-Guide-Filter-Hotels) - [All-inclusive Resorts in Rio de Janeiro State](https://expedia.com/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllinclusiveHotel.Hotel-Filter-Destinations) - [Hotels in Asunción Department](https://expedia.com/Destinations-In-Asuncion-Department.d553248635975177338.Hotel-Destinations) - [Hotels in Galápagos](https://expedia.com/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [Hotels & Resorts for Couples in Cordillera](https://expedia.com/Destinations-In-Cordillera-Couples-Resorts-Hotels.0-0-d3000652124-tCouplesResortsHotels.Hotel-Filter-Destinations) Flights - [Cheap Flights to Galápagos](https://expedia.com/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Cheap Flights to Asunción Department](https://expedia.com/Destinations-In-Asuncion-Department.d553248635975177338.Flight-Destinations) Cars - [Car rentals in Cordillera](https://expedia.com/Destinations-In-Cordillera.d3000652124.Car-Rental-Destinations) Cruises - [Cruises to Galápagos](https://expedia.com/Cruises-to-Galapagos.d1371.Travel-Guide-Cruise) Packages - [Holiday in Galápagos](https://expedia.com/Galapagos.d1371.Destination-Travel-Guides) - [Galápagos All Inclusive Vacation Packages](https://expedia.com/lp/theme-vacations/all-inclusive-vacations/1371/Galapagos) General - [Visit Mato Grosso do Sul](https://expedia.com/Mato-Grosso-Do-Sul.dx6052631) - [Visit Magallanes y Antartica Chilena](https://expedia.com/Magallanes-Y-Antartica-Chilena.dx6236290) - [Visit La Pampa Province](https://expedia.com/La-Pampa-Province.dx6232299) - [Visit Buenos Aires Province](https://expedia.com/Buenos-Aires-Province.dx6054206) - [Visit Santa Fe Province](https://expedia.com/Santa-Fe-Province.dx6232320) - [Visit Paraná](https://expedia.com/Parana.dx6052638) - [Visit San Andrés y Providencia](https://expedia.com/San-Andres-Y-Providencia.dx6226974) - [Visit La Paz](https://expedia.com/La-Paz.dx6297090) - [Visit Valle del Cauca](https://expedia.com/Valle-Del-Cauca.dx6238734) - [Visit Pernambuco](https://expedia.com/Pernambuco.dx6052639) - [Visit Ceará](https://expedia.com/Ceara.dx6052624) - [Visit Santa Catarina](https://expedia.com/Santa-Catarina.dx6052646) - [Visit Entre Ríos Province](https://expedia.com/Entre-Rios-Province.dx6232337) - [Visit Rio Grande do Sul](https://expedia.com/Rio-Grande-Do-Sul.dx6052643) - [Visit Jujuy Province](https://expedia.com/Jujuy-Province.dx6232492) - [Visit Lima Region](https://expedia.com/Lima-Region.dx6235880) - [Visit Cundinamarca](https://expedia.com/Cundinamarca.dx6238682) - [Visit Santa Cruz](https://expedia.com/Santa-Cruz.dx6297178) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - 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