Title: Misiones Department Vacation Packages 2026 | Expedia.com [Misiones Department Hotels](https://expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Hotel-Destinations)[Vacation Rentals in Misiones Department](https://expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Vacation-Rental-Destinations)[Car Rentals in Misiones Department](https://expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Car-Rental-Destinations) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Misiones Department Vacations & Trips ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635975177264) ## Find the Best Misiones Department Vacation Packages ## Misiones Department Essential Information | Language | Spanish | | --------------- | ------------------------------------- | | Currency | Paraguayan guaranís | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Silvio Pettirossi Intl. Airport (ASU) | ## Misiones Department Hotel Deals ![Rio Hotel by Bourbon Ciudad del Este](https://images.trvl-media.com/lodging/19000000/18130000/18123500/18123416/1c8bab57_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Rio Hotel by Bourbon Ciudad del Este Calle Boqueron 305 Ciudad Del Este 9.2/10 Wonderful! (949 reviews) Nice stay, great staff Reviewed on Nov 16, 2025 [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&selected=18123416&PinnedHotelID=18123416&HadPinnedHotel=true®ionId=553248635975177264) [](https://expedia.com/Hotel-Search?startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&selected=18123416&PinnedHotelID=18123416&HadPinnedHotel=true®ionId=553248635975177264) ![Nobile Hotel Convention Ciudad Del Este](https://images.trvl-media.com/lodging/8000000/7400000/7394600/7394562/f2da1e32_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Nobile Hotel Convention Ciudad Del Este Avda. Quito - Km. 7 Ciudad Del Este Fully refundableReserve now, pay when you stay $51 nightly $56 total Feb 18 - Feb 19 Total with taxes and fees 9/10 Wonderful! (620 reviews) Great service overall. Reviewed on Jan 19, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F18%2F2026&endDate=2%2F19%2F2026&selected=7394562&PinnedHotelID=7394562&HadPinnedHotel=true®ionId=553248635975177264) ![Darling Hotel Ciudad del Este](https://images.trvl-media.com/lodging/109000000/108440000/108435900/108435884/223d9bd0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Darling Hotel Ciudad del Este Emiliano R. Fernandez Ciudad Del Este Alto Paraná Fully refundableReserve now, pay when you stay $47 nightly $52 total Mar 12 - Mar 13 Total with taxes and fees 8/10 Very Good! (78 reviews) My one bed room was small. Small bathroom and sink. Breakfast was okay, fruit, pastries, scrambled eggs, sliced cold cut meats, cereals, milk, coffee, tea, orange juice. Check in and out was easy. Reviewed on Jan 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=108435884&PinnedHotelID=108435884&HadPinnedHotel=true®ionId=553248635975177264) [See all 418 properties in Paraguay](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F15%2F2026&endDate=2%2F16%2F2026®ionId=143) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf 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![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) Explore a world of travel with Expedia ## Other vacations you might like - Top cities in Misiones Department - Vacations and getaways similar to Misiones Department - Best vacation destinations by month - [Ayolas Vacations ](https://expedia.com/Ayolas.d3000472762.Destination-Travel-Guides) - [Santa Rosa Vacations ](https://expedia.com/Santa-Rosa.d3000379166.Destination-Travel-Guides) - [Cordillera Vacations ](https://expedia.com/Cordillera.d3000652124.Destination-Travel-Guides) - [San Pedro Department Vacations ](https://expedia.com/San-Pedro-Department.d3000429885.Destination-Travel-Guides) - [Guaira Department Vacations 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](https://www.expedia.com/lp/b/where-to-go/vacations-september) - [October Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-october) - [November Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-november) - [December Vacations and Deals ](https://www.expedia.com/lp/b/where-to-go/vacations-december) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app