Eastern Sicily Vacation Packages 2026 from $1,459

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Your Eastern Sicily Vacation

Head off on your next epic adventure with an Eastern Sicily vacation package, and leave relaxed knowing the finer details are already organized. Plus with the ability to customize your escape, you know it'll be one to remember. Start your trip to Eastern Sicily with some time in Catania visiting popular attractions like Etnaland and Via Etnea. Taormina is another top city that lures crowds from far and wide. Isola Bella and Greek Theatre are two of the top places to see here. Expedia has everything you need for organizing your Eastern Sicily vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.

The Latest Eastern Sicily vacation packages

Price found within the past 48 hours. Click for updated prices.

Ollen apartments

Picanello-Ognina-Barriera-Canalicchio

$1,459

per person

Nov 8 - Nov 14

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.6/10 Exceptional! (26 reviews)

The location was perfect, quiet and safe. The staff were amazing. They were super friendly and helpful. They cooked delicious food and made awesome drinks. Breakfast included and super clean. I would definitely recommend the Ollen Apartments.

Reviewed on Sep 16, 2026

Palazzo Vecchio Taormina

Taormina City Centre

Save 100% on your flight

$3,737

per person

Nov 7 - Nov 14

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.8/10 Exceptional! (62 reviews)

Hotel Metropole Taormina

Taormina City Centre

Save 100% on your flight

$2,485

per person

Nov 7 - Nov 14

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.4/10 Exceptional! (278 reviews)

Best hotel in Taormina! If you want the white lotus vibe, this is it

Reviewed on Sep 12, 2026

Wellness & Spa Hotel Principe di Fitalia

$1,987

per person

Oct 30 - Nov 4

found 3 hours ago

Roundtrip flight included

Boston (BOS) to Catania (CTA)

9.6/10 Exceptional! (97 reviews)

A very well maintained hotel. An excellent pool. Incredibly helpful staff even though we speak very limited Italian and an exceptional breakfast.

Reviewed on Jul 12, 2026

Villa Conrad by Hotel Metropole Taormina

Taormina City Centre

$1,708

per person

Nov 7 - Nov 14

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.2/10 Wonderful! (28 reviews)

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Where to stay in Eastern Sicily

Find the best Eastern Sicily areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Sicily

Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

An ancient ruin with a large rock formation in the background.

Taormina City Centre

1 out of top 10 points of interest in this area

The picturesque gardens and beautiful seaside views are top of the list for many visitors to Taormina City Centre. A stop by Corso Umberto or Piazza IX April might round out your trip.

A castle on a cliff overlooking a lake, surrounded by lush greenery and residential buildings.

Catania City Centre

1 out of top 10 points of interest in this area

Unique features of Catania City Centre include the historic sites and theaters. Make a stop by Via Crociferi or Piazza Stesicoro while you're exploring the area.

A historic stone fortress with arched windows and a central tower.

Old Town Catania

1 out of top 10 points of interest in this area

Baroque architecture and elegant piazzas decorate the historic core of a city framed by Mount Etna and filled with exciting attractions to suit varied interests.

A river with rocky shores, a bridge, and buildings on a hillside.

Mazzaro

The pristine beaches and ample dining options are top of the list for many visitors to Mazzaro. A stop by Lido Mazzaro or Isola Bella might round out your trip.

Stay near popular Eastern Sicily attractions

A beach with footprints, a mountain, and a city in the background.

Catania Beach

7.6/10 (368 reviews)

Why not spend a carefree afternoon at Catania Beach during your travels in Catania?

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A sailboat on a calm sea with a cityscape and a snow-capped mountain in the background.

Catania Port

7.6/10 (449 reviews)

Explore the waterfront in Catania with a trip to Catania Port. Discover the theater scene and cathedral in this culturally rich area.

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A snow-capped mountain at sunset with a village in the foreground.

Mount Etna

9.4/10 (212 reviews)

This tranquil city is in a stupendous position on the sea in front of Mount Etna, with a mild climate year round and marvellous scenery, where peace and quiet reign supreme. It's been world famous for centuries, which has brought an influx of noteworthy tourists, even today, thanks to the numerous holiday promotions for Taormina.

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A historic building with a dome and statues, surrounded by trees and people.

Piazza del Duomo

9.2/10 (1,188 reviews)

Elegant fountains, a superb cathedral and fine shopping and dining make Catania’s main square a great place to spend some time.

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A historic building with ornate balconies, pink flowers, and a street lamp.

Corso Umberto

9.0/10 (929 reviews)

During your visit to Taormina, you can enjoy retail therapy at Corso Umberto. While in this walkable area, you can savor the top-notch restaurants.

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A white cable car with a metal frame, a mesh window, and a door.

Taormina Cable Car

8.8/10 (866 reviews)

On this quick and practical lift system, appreciate the picturesque views as you soar above the beaches and coves of Mazzarò and spot the historic landmarks of Taormina.

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Port of Pozzallo

8.6/10 (25 reviews)

Explore the waterfront in Zona Portuale with a trip to Port of Pozzallo.

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Eastern Sicily Hotel Deals

Palace Catania | UNA Esperienze

Via Etnea 218 Catania CT

Fully refundableReserve now, pay when you stay

$297 nightly

$336 total

Oct 13 - Oct 14

Total with taxes and fees

9.2/10 Wonderful! (1,001 reviews)

"Location. Breakfast."

Reviewed on Sep 24, 2026

Quiete Taormina Naxos, Tapestry Collection by Hilton

Via dei Sei Mulini Giardini Naxos ME

Fully refundableReserve now, pay when you stay

$175 nightly

$202 total

Oct 26 - Oct 27

Total with taxes and fees

UNA Hotels Capotaormina

Via Nazionale, 105 Taormina ME

$279 nightly

$316 total

Oct 11 - Oct 12

Total with taxes and fees

9.2/10 Wonderful! (1,000 reviews)

"No light fixture on two bulbs. Sink looks like something wasn’t correct. The carpet and old elevators were terrible"

Reviewed on Sep 22, 2026

See all 14,003 properties in Eastern Sicily

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.