Eastern Sicily Vacation Packages 2026 from $1,153

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Your Eastern Sicily Vacation

Head off on your next epic adventure with an Eastern Sicily vacation package, and leave relaxed knowing the finer details are already organized. Plus with the ability to customize your escape, you know it'll be one to remember. Start your trip to Eastern Sicily with some time in Catania visiting popular attractions like Etnaland and Via Etnea. Taormina is another top city that lures crowds from far and wide. Isola Bella and Greek Theatre are two of the top places to see here. Expedia has everything you need for organizing your Eastern Sicily vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.

The Latest Eastern Sicily vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Amarea

$1,153

per person

Sep 20 - Sep 26

found 20 hours ago

Roundtrip non-stop flight included

New York (NYC) to Catania (CTA)

8.2/10 Very Good! (56 reviews)

Staff Allessia lovely. The hotel awful

Reviewed on Sep 20, 2018

The Ashbee Hotel - The Leading Hotels of the World

Save 100% on your flight

$4,297

per person

Oct 12 - Oct 15

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.2/10 Wonderful! (143 reviews)

Wellness & Spa Hotel Principe di Fitalia

$1,832

per person

Oct 11 - Oct 17

found 1 day ago

Roundtrip flight included

New York (NYC) to Catania (CTA)

9.6/10 Exceptional! (96 reviews)

A very well maintained hotel. An excellent pool. Incredibly helpful staff even though we speak very limited Italian and an exceptional breakfast.

Reviewed on Jul 12, 2026

Castello San Marco Charming Hotel & Spa

Save 100% on your flight

$6,384

per person

Sep 13 - Sep 19

found 24 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.4/10 Exceptional! (192 reviews)

Incredible stay with incredibly kind and professional staff. Breakfast was wonderful. Will definitely be back to visit!

Reviewed on Aug 9, 2026

Duomo Suites & Spa

Catania City Centre

$1,583

per person

Sep 14 - Sep 19

found 17 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9/10 Wonderful! (458 reviews)

We had a nice stay!

Reviewed on Aug 4, 2026

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Where to stay in Eastern Sicily

Find the best Eastern Sicily areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Sicily

Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

An ancient ruin with a large rock formation in the background.

Taormina City Centre

The picturesque gardens and beautiful seaside views are top of the list for many visitors to Taormina City Centre. A stop by Corso Umberto or Piazza IX April might round out your trip.

A castle on a cliff overlooking a lake, surrounded by lush greenery and residential buildings.

Catania City Centre

1 out of top 10 points of interest in this area

Unique features of Catania City Centre include the historic sites and theaters. Make a stop by Via Crociferi or Piazza Stesicoro while you're exploring the area.

A historic stone fortress with arched windows and a central tower.

Old Town Catania

1 out of top 10 points of interest in this area

Baroque architecture and elegant piazzas decorate the historic core of a city framed by Mount Etna and filled with exciting attractions to suit varied interests.

A river with rocky shores, a bridge, and buildings on a hillside.

Mazzaro

The pristine beaches and ample dining options are top of the list for many visitors to Mazzaro. A stop by Lido Mazzaro or Isola Bella might round out your trip.

Stay near popular Eastern Sicily attractions

A beach with footprints, a mountain, and a city in the background.

Catania Beach

7.6/10 (368 reviews)

Why not spend a carefree afternoon at Catania Beach during your travels in Contrada Pantano d'Arci?

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A snow-capped mountain at sunset with a village in the foreground.

Mount Etna

9.4/10 (212 reviews)

This tranquil city is in a stupendous position on the sea in front of Mount Etna, with a mild climate year round and marvellous scenery, where peace and quiet reign supreme. It's been world famous for centuries, which has brought an influx of noteworthy tourists, even today, thanks to the numerous holiday promotions for Taormina.

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