Eastern South Dakota Vacations from $489
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Your Eastern South Dakota Vacation
Locking in one of our vacation packages to Eastern South Dakota makes it a breeze to see and do more. Get set to experience this exciting destination's rural countryside and beyond. Your trip to Eastern South Dakota wouldn't be complete without getting to some of its best cities, starting with Sioux Falls. Some of the most popular attractions here include Denny Sanford Premier Center and Empire Mall. Mitchell is another favorite with Eastern South Dakota travelers. Visitors to this exciting destination enjoy Corn Palace and Mitchell Aquatic Center. Start packing your bags, because your Eastern South Dakota vacation is just a few clicks away with Expedia.
The Latest Eastern South Dakota vacation packages
Microtel Inn & Suites by Wyndham Sioux Falls
Reviewed on Mar 1, 2026
Hotel On Phillips
Reviewed on Mar 3, 2026
AeroStay Hotel
Reviewed on Mar 2, 2026
Where to stay in Eastern South Dakota
Downtown Sioux Falls
While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.
Discover the most popular places to visit in Eastern South Dakota
Falls Park
Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.
Corn Palace
After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.
Great Plains Zoo
Why not visit the native and exotic animals who live at Great Plains Zoo during your travels in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
Eastern South Dakota Hotel Deals
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Elevator got stuck. No out of order sign. Cheap rates. No free breakfast. Friendly staff. Room was pretty clean besides some mystery stains on the sides of the mattresses. The pull out couch mattress was paper thin and was impossible to sleep on. Hot tub water looked brown. Room smelled like dirt ...
Reviewed on Mar 3, 2026
Hotel On Phillips
Everything was so clean so quiet and we really enjoyed the stay and we will go stay again.
Reviewed on Mar 3, 2026
La Quinta Inn & Suites by Wyndham Sioux Falls
Clean room clean beds
Reviewed on Feb 27, 2026
Find the Best Eastern South Dakota Vacation Packages
Eastern South Dakota Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Sioux Falls Regional Airport (FSD) |
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