Eastern South Dakota Vacations from $418
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Your Eastern South Dakota Vacation
Locking in one of our vacation packages to Eastern South Dakota makes it a breeze to see and do more. Get set to experience this exciting destination's rural countryside and beyond. Your trip to Eastern South Dakota wouldn't be complete without getting to some of its best cities, starting with Sioux Falls. Some of the most popular attractions here include Denny Sanford Premier Center and Empire Mall. Mitchell is another favorite with Eastern South Dakota travelers. Visitors to this exciting destination enjoy Corn Palace and Mitchell Aquatic Center. Start packing your bags, because your Eastern South Dakota vacation is just a few clicks away with Expedia.
The Latest Eastern South Dakota vacation packages
Price found within the past 48 hours. Click for updated prices.
Microtel Inn & Suites by Wyndham Sioux Falls
Mall District
Price was $729, price is now $641 per person
$641
per person
Jun 22 - Jun 26
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Sioux Falls (FSD)
7.6/10 Good! (39 reviews)
Internet speed was excellent here. Other than that I was very disappointed with staying here. I mean, if this place were out in western South Dakota, it would be okay but for Sioux Falls, there are so many better options. When we first checked in on Sunday I wanted to take a shower but we had no towels until after 5 p.m. Garbage bin on rear of motel was overflowing throughout our stay. Waffle machine could not cook evenly. Milk at breakfast was warm on the first day. We did enjoy the live prairie dog that apparently lives just outside of our room. (That is outside of our window.) The thermostat on the air conditioning/heating unit was very weird. Apparently a setting of 72 degrees on heat bears no relationship to the same setting when the unit is set to cool. Staff was friendly enough. Microtel Inns have way of sucking all the useful space out of a room and this Microtel was no exception. The worst issue of all had to do with our bed frames. The mattresses were a bit too small for the frame so WATCH OUT. Like us, you may find yourself with some bruises after your stay.
Reviewed on May 20, 2026
Highpoint Hotel
University Heights
Price was $847, price is now $752 per person
$752
per person
Jun 22 - Jun 26
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Sioux Falls (FSD)
9.8/10 Exceptional! (75 reviews)
Nice, spacious and clean room. Common areas were very nicely appointed.
Reviewed on May 19, 2026
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View all tripsWhere to stay in Eastern South Dakota
Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota
Downtown Sioux Falls
1 out of top 10 points of interest in this area
4.5/5(111 area reviews)
While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.
Discover the most popular places to visit in Eastern South Dakota
Falls Park
Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.
Corn Palace
After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.
Great Plains Zoo
Why not visit the native and exotic animals who live at Great Plains Zoo during your travels in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
Eastern South Dakota Hotel Deals
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
1301 West Russell Sioux Falls SD
$65 nightly
The price is $74 total per night from May 31 to Jun 1
$74 total
May 31 - Jun 1
Total with taxes and fees
7.8/10 Good! (1,564 reviews)
"The person that checked us in was just incredible. She was kind and friendly and all around very personable. The property itself was wonderful for a family trip to an indoor pool area. It was really cool. The pizza place/bar hooked on was so good. My only complaint was that it was very dark inside, ..."
Reviewed on May 19, 2026
Hotel On Phillips
100 N Phillips Ave Sioux Falls SD
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $194 total per night from Jun 7 to Jun 8
$194 total
Jun 7 - Jun 8
Total with taxes and fees
9.6/10 Exceptional! (1,418 reviews)
"Our favorite SF stay, every time"
Reviewed on May 18, 2026
AeroStay Hotel
2821 N Jaycee Lane Sioux Falls SD
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from May 25 to May 26
$134 total
May 25 - May 26
Total with taxes and fees
8.8/10 Excellent! (1,111 reviews)
"The hotel was nice, but there was a lot construction type work going on. The room numbers were taped on the doors. There was a huge room on the first that had lots of stuff like work supplies that the guests see, which looked really messy. Also, there was a conference room on the first floor that ..."
Reviewed on May 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Eastern South Dakota Vacation Packages
Eastern South Dakota Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Sioux Falls Regional Airport (FSD) |
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