
Esquilino Vacations from $1,160
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Your Esquilino Vacation
Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.
The Latest Esquilino Vacation Packages


Albergo Etico Roma
Reviewed on Feb 21, 2026

Exe International Palace
Reviewed on Feb 3, 2026

TB Place Roma
Reviewed on Feb 22, 2026

Hotel Splendide Royal - The Leading Hotels of the World
Reviewed on Feb 28, 2026
Where to stay in Esquilino

Rome City Centre
Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.
Esquilino Hotel Deals

NH Collection Roma Palazzo Cinquecento
Staff at reception not particularly friendly or welcoming.
Reviewed on Mar 6, 2026

Hotel Aphrodite
I have very bad allergies when staying in this hotel. Not sure what exactly am I allergic to in the room. Other than that, hotel is okay.
Reviewed on Mar 2, 2026

Mecenate Palace
Very courteous and helpful staff. Great breakfast. Location very convenient to Roma Termini.
Reviewed on Mar 3, 2026
Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore
Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Piazza Vittorio Emanuele II
Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Basilica di Santa Croce in Gerusalemme
Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Things to do

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour























