Esquilino Vacations from $670

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Your Esquilino Vacation

Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.

The Latest Esquilino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,187, price is now $670 per person
$670
per person
Dec 8 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (574 reviews)
Best location. Clean. Mattress was a little bit hard. Would recommend

Reviewed on Oct 5, 2025

Monastero dei Santi

Monastero dei Santi

5 out of 5
Municipio I
Save 100% on your flight
Price was $1,373, price is now $815 per person
$815
per person
Dec 8 - Dec 13
found 13 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
10/10 Exceptional! (23 reviews)
Elegant and renovated boutique hotel

Reviewed on Jul 5, 2025

The Fifteen Keys Hotel

The Fifteen Keys Hotel

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,591, price is now $1,048 per person
$1,048
per person
Dec 8 - Dec 13
found 13 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (367 reviews)
Amazing- would stay again

Reviewed on Sep 29, 2025

Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Price was $1,200, price is now $756 per person
$756
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.4/10 Good! (1,020 reviews)
Position was great for shopping and eating

Reviewed on Oct 4, 2025

Rhinoceros

Rhinoceros

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,072, price is now $1,359 per person
$1,359
per person
Nov 26 - Dec 1
found 12 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (23 reviews)
A one of a kind hotel. From the finishes of the building, story of how the hotel came about, truly an incredible hotel right in the heart of Rome.

Reviewed on Aug 28, 2025

Where to stay in Esquilino

Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Esquilino Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105, Rome, RM
$171 nightly
The price is $205 total per night from Nov 2 to Nov 3
$205 total
Nov 2 - Nov 3
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"The hotel itself is quite nice. The rooms very comfortable. Everything was quite clean. The restaurant in the hotel was nice. The rooftop bar was fun. The hotel is conveniently located near enough to the train station to walk, but far enough to not be bothered by it. Naples, unfortunately is not ..."

Reviewed on Sep 29, 2025

Napoleon Hotel
Hotel Morgana

Hotel Morgana

4 out of 5
Via Filippo Turati 31 33 35, Rome, RM
$158 nightly
The price is $192 total per night from Nov 4 to Nov 5
$192 total
Nov 4 - Nov 5
Total with taxes and fees
8.2/10 Very Good! (998 reviews)
"I would highly recommend others to try this hidden gem in Rome. Not only are the staff to be commended for their wonderful help and guidance, but the overall stay was for me, just superb. It’s a place I would return too without hesitation."

Reviewed on Sep 24, 2025

Hotel Morgana
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90, Rome, RM
$366 nightly
The price is $426 total per night from Nov 1 to Nov 2
$426 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
"Good location and much more peaceful than the historic centres. Excellent breakfast buffet. Helpful staff."

Reviewed on Sep 12, 2025

NH Collection Roma Palazzo Cinquecento
See all 691 properties in Esquilino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore

Piazza Santa Maria Maggiore

3.5/5(3 reviews)

Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed theater scene and fascinating museums in this vibrant area.

Piazza Santa Maria Maggiore
Palm Trees in the Evening Light

Piazza Vittorio Emanuele II

5/5(1 review)

Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Piazza Vittorio Emanuele II

Basilica di Santa Croce in Gerusalemme

5/5(1 review)

Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed theater scene and notable monuments in this vibrant area.

Basilica di Santa Croce in Gerusalemme

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$34
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.