Esquilino Vacations from $1,179

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Your Esquilino Vacation

Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.

The Latest Esquilino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Albergo Etico Roma

Albergo Etico Roma

Flaminio
Save 100% on your flight
$1,179
per person
Oct 30 - Nov 3
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.8/10 Exceptional! (379 reviews)
Monastero dei Santi

Monastero dei Santi

Municipio I
Save 100% on your flight
$2,643
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (31 reviews)
U-Visionary Roma Hotel

U-Visionary Roma Hotel

Rome City Centre
Save 100% on your flight
$3,070
per person
Nov 11 - Nov 17
found 13 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Rome (FCO)
9.6/10 Exceptional! (502 reviews)
Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Pinciano
Save 100% on your flight
$2,237
per person
Oct 24 - Oct 30
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9/10 Wonderful! (892 reviews)
We enjoyed a wonderful stay at Parco Dei Principi, celebrating our Silver Wedding. Staff were without exception lovely, and the large, well-appointed and comfortable room was very good value. We greatly appreciated having a spa, gym and two pools to choose from. On the minus side were a couple of small things: a leak from upstairs into the bathroom which we reported to staff for fixing, and an ill-fitting bathroom door. The new restaurant was expensive (as one would expect in a 5-star hotel), but the menu didn't appeal to us and we didn't try it. But overall we'd thoroughly recommend this hotel.

Reviewed on Sep 3, 2026

Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
$1,297
per person
Nov 14 - Nov 18
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Rome (FCO)
No reviews

Where to stay in Esquilino

Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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Esquilino Hotel Deals

Napoleon Hotel

Napoleon Hotel

Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
$148 nightly
$163 total
Sep 9 - Sep 10
Total with taxes and fees
8.6/10 Excellent! (1,033 reviews)
"The hotel was extremely old and not kept up. Could use an overhaul to the entire hotel."

Reviewed on Sep 7, 2026

Napoleon Hotel
Hotel Terminal

Hotel Terminal

Via Principe Amedeo 103 Rome RM
Fully refundableReserve now, pay when you stay
$115 nightly
$140 total
Sep 13 - Sep 14
Total with taxes and fees
7.6/10 Good! (440 reviews)
"La habitación es súper pequeña, las condiciones de la cama no es bueno, para pasar una solo noche pasa. Lo bueno es que está muy bien ubicado."

Reviewed on Sep 7, 2026

Hotel Terminal
Rome Experience Hostel

Rome Experience Hostel

Via Statilia 31 Rome RM
$49 nightly
$70 total
Sep 10 - Sep 11
Total with taxes and fees
6.4/10 (168 reviews)
"The room was fine, as expected from the photos, but make sure you have locks on your bags and don’t leave your bags in the room without you there. There are no lockers in the room, the only lockers are by reception which is nice because someone is always there, but most of the locker doors are busted ..."

Reviewed on Jun 23, 2026

Rome Experience Hostel
See all 758 properties in Esquilino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Esquilino attractions

Piazza Santa Maria Maggiore

8.0/10 (7 reviews)
Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed art scene and fascinating museums in this vibrant area.
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Piazza Vittorio Emanuele II

8.6/10 (4 reviews)
Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Basilica di Santa Croce in Gerusalemme

9.4/10 (3 reviews)
Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Historic Museum of the Liberation

You can browse the exhibits at Historic Museum of the Liberation, a museum with a storied past, during your travels to Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.
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La Scala Sancta

Learn about the local history of Rome with a stop at La Scala Sancta. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Teatro Ambra Jovinelli

Enjoy a performance at Teatro Ambra Jovinelli, a storied theater in Rome. Discover the fascinating museums and churches in this vibrant area.
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Giardini Nicola Calipari

Enjoy an outing to Giardini Nicola Calipari during your stay in Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Palace of the Holy Steps

You can learn about the history of Rome when you stop by Palace of the Holy Steps (Santuario della Scala Santa). Visit the stunning cathedral and notable monuments in this vibrant area.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Culinary Delights: Cooking Class and Market Food Tour in Rome

Rome Pasta and Gelato Cooking Class a Hands-On Italian Culinary Experience

$87
per adult
100% of travellers recommend
Rome Pasta and Gelato Cooking Class a Hands-On Italian Culinary Experience
3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu

Rome 3 in 1 Cooking Class: Fettuccine, Ravioli & Tiramisu

$61
per adult
98% of travellers recommend
Rome 3 in 1 Cooking Class: Fettuccine, Ravioli & Tiramisu
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.