
Esquilino Vacations from $962
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Your Esquilino Vacation
Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.
The Latest Esquilino Vacation Packages

Hotel Delle Civette
Reviewed on Feb 8, 2026

Palazzo Nainer
Reviewed on Feb 15, 2026

Relais de la Poste
Reviewed on Feb 10, 2026

Albergo Etico Roma
Reviewed on Feb 10, 2026

U-Visionary Roma Hotel
Reviewed on Jan 3, 2026
Where to stay in Esquilino

Rome City Centre
Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.
Esquilino Hotel Deals

Napoleon Hotel
Great location, spacious room, fantastic service. Need to tune the piano in the lobby :)
Reviewed on Feb 10, 2026

Hotel Terminal
Luggage storage was great! Across the street from a good restaurant. Close to the train station. Elevator was small. One person and their luggage at a time. Unable to adjust ac/heat so room was hot. Thankfully we opened the window. Beds were small & uncomfortable but it did the job. We were just ...
Reviewed on Feb 8, 2026

Hotel Contilia
After a last seconf cancelation by a different host, I ended up at this property and have a very good expperience. The staff were kind in helping me get my reservation changed over. The room was spotless and cleaned daily. Overall, a great experience!
Reviewed on Nov 10, 2025
Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore
Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Piazza Vittorio Emanuele II
Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Basilica di Santa Croce in Gerusalemme
Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica























