Esquilino Vacations from $783

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Your Esquilino Vacation

Avoid the hassle of travel planning with an Esquilino vacation package. With everything organized before you take off, all that's left to do is enjoy this commercial neighborhood's history, dining and culture. Not sure what to do and see during your trip to Esquilino? Nearby attractions like St. Peters Basilica, Roman Forum and Pantheon are great places to start. Don't just imagine it — turn it into reality! Book your ideal Esquilino vacation with Expedia and travel your way.

The Latest Esquilino Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Villa Grazioli

Hotel Villa Grazioli

4 out of 5
Parioli
Price was $1,081, price is now $783 per person
$783
per person
Jan 1 - Jan 8
found 19 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8.2/10 Very Good! (167 reviews)
Everything very good but the building and common spaces are a bit old

Reviewed on Oct 4, 2025

TB Place Roma

TB Place Roma

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,684, price is now $1,154 per person
$1,154
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (43 reviews)
We pretty much likes everything about the property. My wife and I travel a lot and normally go to very good hotels which are bigger, but we wanted to try a boutique hotel this time and it did not disappoint. We stayed for 6 nights. For starters, their people are wonderful, with a special shout out to Martina at the front desk and the young lady that runs the breakfast (we should know her name). The location is great, the hotel is in great condition. We stayed in a junior suite and it was a really good size. We tend to be on the picky side, and honestly we can’t find anything bad to say. Keep it up!

Reviewed on Jun 1, 2025

ROMANICO PALACE LUXURY HOTEL & SPA

ROMANICO PALACE LUXURY HOTEL & SPA

4 out of 5
Rome City Centre
Price was $1,457, price is now $1,035 per person
$1,035
per person
Jan 1 - Jan 8
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
7.8/10 Good! (740 reviews)
The room was very nice. Just a little small, but beautiful. We don't drink.

Reviewed on Oct 19, 2025

Room Select Via Veneto

Room Select Via Veneto

4 out of 5
Rome City Centre
Price was $1,222, price is now $890 per person
$890
per person
Jan 1 - Jan 8
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8.8/10 Excellent! (233 reviews)
Great area, not far from Trevi Fountain or Roma Termini

Reviewed on Oct 15, 2025

EXE Domus Aurea

EXE Domus Aurea

3 out of 5
Rome City Centre
Price was $1,132, price is now $832 per person
$832
per person
Nov 29 - Dec 6
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8/10 Very Good! (483 reviews)
Good location and friendly staff. Although this didn’t bother me, it could be a bit noisy at night due to some night walkers on the street.

Reviewed on Nov 19, 2024

Where to stay in Esquilino

Find the best Esquilino areas and neighborhoods for the activities you enjoy most. Learn more about Esquilino
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Esquilino Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105, Rome, RM
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $191 total per night from Nov 2 to Nov 3
$191 total
Nov 2 - Nov 3
Total with taxes and fees
8.2/10 Very Good! (1,018 reviews)
"The staff was fantastic.Unfortunately outside the neighborhood is filthy"

Reviewed on Oct 18, 2025

Napoleon Hotel
Hotel Aphrodite

Hotel Aphrodite

4 out of 5
Via Marsala 90, Rome, RM
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $165 total per night from Nov 18 to Nov 19
$165 total
Nov 18 - Nov 19
Total with taxes and fees
7.6/10 Good! (995 reviews)
One night super comfortable
"We had to stay in Rome for 1 night due to a flight delay. Hotel Aphrodite was a great choice. Very close to Roma termini. Perfect breakfast. Friendly staff"

Reviewed on Oct 13, 2025

Hotel Aphrodite
Hotel Terminal

Hotel Terminal

3 out of 5
Via Principe Amedeo 103, Rome, RM
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $105 total per night from Nov 3 to Nov 4
$105 total
Nov 3 - Nov 4
Total with taxes and fees
7.6/10 Good! (304 reviews)
"Great place."

Reviewed on Oct 16, 2025

Hotel Terminal
See all 681 properties in Esquilino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Esquilino

Piazza Santa Maria Maggiore

Piazza Santa Maria Maggiore

3.5/5(3 reviews)

Find out about the history of Rome when you take a trip to Piazza Santa Maria Maggiore. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Piazza Santa Maria Maggiore
Palm Trees in the Evening Light

Piazza Vittorio Emanuele II

5/5(1 review)

Explore the great outdoors at Piazza Vittorio Emanuele II, a lovely green space in Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Piazza Vittorio Emanuele II

Basilica di Santa Croce in Gerusalemme

5/5(1 review)

Find out about the history of Rome when you take a trip to Basilica di Santa Croce in Gerusalemme. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Basilica di Santa Croce in Gerusalemme

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.