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Book Greenville Bed & Breakfast

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    Check prices for these dates, December 13 – 14, 2026

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    Recommended hotels in Greenville

    1. Hotel 27

    Breakfast area

    2. Harlow's Casino Resort & Spa

    A person sitting by a pool with clear blue water, wearing a white bikini and a large straw hat.

    3. Tru By Hilton Greenville

    A modern reception area with a curved counter, seating with cushions, and a view of the outdoors.

    4. Holiday Inn Express and Suites Greenville by IHG

    A spacious living room with a large sofa, armchairs, and a fireplace.

    5. Hampton Inn

    A hotel reception area with a coffee station, a wall with a colorful pattern, and a sofa in the background.

    6. Cotton House, Cleveland, a Tribute Portfolio Hotel

    A spacious living area with a wooden floor, a sofa, a coffee table, and a dining area visible through a glass door.

    7. Days Inn by Wyndham Greenville MS

    A hotel room with two beds, a desk, a chair, and artwork on the wall.

    8. Econo Lodge Greenville

    A modern hotel dining area with a large table and chairs, a kitchen area with appliances, and a large window offering a view.

    9. Americas Best Value Inn & Suites Greenville

    A spacious room with wooden flooring, beige sofas, a wooden coffee table, and large windows offering a view of the outdoors.

    10. Quality Inn Indianola

    A modern lounge area with leather sofas, a glass-top coffee table, and a brick wall with a fireplace.

    11. Lyric Hotel West End, Trademark Collection by Wyndham

    A modern restaurant with brick walls, multiple seating areas, and pendant lighting.

    12. The 'Serene' Retreat has everything you need. You will feel like this is HOME!

    A living room with a white sofa, a coffee table, and a ceiling fan. There is a dining area visible through an open door.

    13. Super 8 by Wyndham Indianola

    A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

    14. Holiday Inn Express Hotel & Suites Cleveland by IHG

    A buffet with labeled sections for omelets and cheese.

    15. Motel 6 Cleveland, MS - Delta State University

    A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

    16. Honnoll's High Cotton Guest House

    A bedroom with a wooden headboard, a quilted bedspread, and a nightstand.

    17. Peaceful country home in charming Indianola great for entertaining or relaxing

    Room

    18. c towninn and suites

    A hotel room with a bed, a dresser, a television, and a small refrigerator.

    19. Americas Best Value Inn Indianola

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    20. Days Inn by Wyndham Lake Village

    A hotel room with two beds, a wooden headboard, a large landscape painting, and a nightstand with a phone.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Greenville and related destinations

    The birthplace of blues legends offers visitors a moving journey along the Mississippi Blues Trail and riverfront museums. Spend afternoons exploring historic downtown shops before catching live music at local venues where talented musicians honor the city's rich musical heritage.

    See all hotels in Greenville

    A suspension bridge over a river with a cargo ship in the water.

    Top reviews in Greenville

    Turn On Inn

    Property amenity

    Hotel 27

    Breakfast area

    Cotton House, Cleveland, a Tribute Portfolio Hotel

    A spacious living area with a wooden floor, a sofa, a coffee table, and a dining area visible through a glass door.

    Lyric Hotel West End, Trademark Collection by Wyndham

    A modern restaurant with brick walls, multiple seating areas, and pendant lighting.

    Tru By Hilton Greenville

    A modern reception area with a curved counter, seating with cushions, and a view of the outdoors.

    Motel 6 Cleveland, MS - Delta State University

    A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

    Holiday Inn Express and Suites Greenville by IHG

    A spacious living room with a large sofa, armchairs, and a fireplace.

    Harlow's Casino Resort & Spa

    A person sitting by a pool with clear blue water, wearing a white bikini and a large straw hat.

    Quality Inn Indianola

    A modern lounge area with leather sofas, a glass-top coffee table, and a brick wall with a fireplace.

    Americas Best Value Inn Indianola

    Room

    Super 8 by Wyndham Indianola

    A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

    Days Inn by Wyndham Lake Village

    A hotel room with two beds, a wooden headboard, a large landscape painting, and a nightstand with a phone.

    Americas Best Value Inn & Suites Greenville

    A spacious room with wooden flooring, beige sofas, a wooden coffee table, and large windows offering a view of the outdoors.

    Econo Lodge Greenville

    A modern hotel dining area with a large table and chairs, a kitchen area with appliances, and a large window offering a view.

    Rolling Fork Motel

    A hotel room with a large bed, a desk, a chair, a nightstand with a lamp, and two framed pictures on the walls.

    Frequently Asked Questions

    What is the nightly rate for a Bed and Breakfast in Greenville?

    Prices for B&Bs in Greenville often vary, but you can find a great deal from $59 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Greenville B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.

    When is the best time to book a Bed & Breakfast in Greenville?

    The best time to book a B&B in Greenville is during the vibrant months of April to June, when the city comes alive with spring blooms and outdoor activities. This peak season offers a delightful mix of comfortable weather and abundant opportunities for exploration. With temperatures ranging from the mid-50s to mid-80s Fahrenheit, visitors can enjoy leisurely strolls through parks, take part in local festivals, or explore the picturesque downtown area.

    April is particularly charming, as the city’s gardens burst into color, creating a stunning backdrop for outdoor events and sightseeing. It's an ideal time for those who appreciate a blend of culture and nature, with easy access to scenic trails and the enchanting Reedy River.

    If you're looking for a more budget-friendly experience, consider visiting in November. This month often features mild weather and fewer crowds, allowing for peaceful exploration of the local attractions and cozy evenings at your chosen B&B. Enjoy the charm of Greenville’s autumn foliage while savoring a relaxing atmosphere away from the busier tourist season.

    What is the difference between a Greenville Bed & Breakfast and a hotel?

    Every Greenville B&B has its own unique feel. Whether it’s a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Greenville B&Bs.

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