Greenville Vacations from $313

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Greenville vacation packages

Price found within the past 48 hours. Click for updated prices.
White House at Grand Central

White House at Grand Central

4 out of 5
Grand Center
Save 100% on your flight
Price was $479, price is now $313 per person
$313
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (123 reviews)
Very clean and very friendly people

Reviewed on Nov 11, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $614, price is now $367 per person
$367
per person
Feb 13 - Feb 15
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
We enjoyed our stay! Close to skiing and tubing. Lots of restaurants close. Kids loves the small swimming pool

Reviewed on Jan 7, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $605, price is now $447 per person
$447
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
Loved the uniqueness of Cheshire inn and the themed rooms by authors. Had a great breakfast! Also the Fox and Hound Tavern inside and the Basso just a few steps away out the door. The one thing I did miss was having a mini fridge and microwave.

Reviewed on Jan 4, 2026

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $628, price is now $472 per person
$472
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (996 reviews)
Beautiful hotel, very clean. Dinner at restaurant was subpar.

Reviewed on Jan 7, 2026

Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
Woodson Terrace
Price was $589, price is now $454 per person
$454
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.6/10 Good! (1,000 reviews)
Room was good. Appearance is somewhat dated

Reviewed on Jan 3, 2026

Don't see what you're looking for?
See all available trips from Columbus to Greenville
View all trips

Discover the most popular places to visit in Greenville

Greenville Country Club

Enjoy a round of golf in Greenville at Greenville Country Club. You'll find more to see and do in this family-friendly area.

Greenville Country Club

Patriot's Park

You can take time to visit Patriot's Park during your travels to Greenville. Wander the parks in this family-friendly area.

Patriot's Park

Greenville Hotel Deals

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Jan 21 to Jan 22
$70 total
Jan 21 - Jan 22
Total with taxes and fees
7.8/10 Good! (767 reviews)
Room was clean and beds were super comfortable. Breakfast was nothing special, but it was plenty of variety for our family. Staff was friendly.

Reviewed on Jan 3, 2026

Super 8 by Wyndham Greenville
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 out of 5
2265 S. State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Feb 1 to Feb 2
$100 total
Feb 1 - Feb 2
Total with taxes and fees
8.4/10 Very Good! (418 reviews)
Good

Reviewed on Nov 29, 2025

Comfort Inn & Suites Greenville I-70
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

2.5 out of 5
1731 S State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $70 total per night from Jan 18 to Jan 19
$70 total
Jan 18 - Jan 19
Total with taxes and fees
7.4/10 Good! (563 reviews)
Clean room, a little outdated but the comfortable bed more than makes up for that. Heard a few loud vehicles early in the evening next door but by 10 pm it was quiet. Room was spacious and easy to get to.

Reviewed on Dec 24, 2025

SureStay Hotel by Best Western Greenville
See all 62 properties in Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Greenville Vacation Packages

Greenville Essential Information

Language
English
Currency
U.S dollars
Population
6,700
Max Temp Winter
40ºF
Max Temp Summer
80ºF

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Greenville vacation package cost?
Offering great value package deals from $313 on Expedia, you'll be pleasantly surprised at how much a vacation to Greenville costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Greenville?
If you're looking to score a cheap Greenville vacation package, consider visiting in January, March and December. You'll typically find lower prices on hotels and airfares during these months — perfect for travelers wishing to save money.
How many days is enough for Greenville?
Generally, a handful of days is enough to visit the major attractions during your Greenville vacation. However, if you want to have some time to unwind or take day tours, consider extending your itinerary.
How to find the best Greenville package deals?
Use Expedia's handy filters to find some great Greenville package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Greenville package deals in the off-season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Greenville vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll usually get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Greenville vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Greenville?
Enjoy incredible discounts by booking your flights in advance with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Greenville escape.
Does Expedia offer Book Now, Pay Later Greenville vacation packages?
If you're like us, you love exploring new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Greenville vacation over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.