Greenville Vacations from $332

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The Latest Greenville vacation packages

Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Save 100% on your flight
Price was $461, price is now $332 per person
$332
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,981 reviews)
When we got in late on Wednesday night, our room was not available. Some BS story about not being cleaned. We had to drive around for hours looking for another place to stay and it cost $400 for one night. The rooftop bars were not available due to either rain or heat. The restaurant closed early every day for breakfast and for dinner.

Reviewed on Jun 30, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $500, price is now $359 per person
$359
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,000 reviews)
fun place to stay and a great location

Reviewed on Jun 30, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $946, price is now $749 per person
$749
per person
Aug 17 - Aug 22
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
Such a great place to stay! We had the best time and will be back

Reviewed on Jun 30, 2026

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
Save 100% on your flight
Price was $425, price is now $339 per person
$339
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,003 reviews)
Great value but room not clean. The floor was not vacuumed. Desk staff covering desk and Starbucks cafe at same time. Guests had to wait due to short staffing.

Reviewed on Jun 27, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was $764, price is now $610 per person
$610
per person
Aug 17 - Aug 22
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.8/10 Excellent! (1,074 reviews)
Beautiful rooms

Reviewed on Jun 30, 2026

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Stay near popular Greenville attractions

Patriot's Park

8.4/10 (14 reviews)
This peaceful community park offers scenic trails around a serene lake, plus disc golf and playgrounds. Enjoy a morning walk through wooded areas to spot local wildlife or cast a line for some relaxing fishing.
See properties

Greenville Hotel Deals

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 out of 5
2265 S. State Route 127 Greenville IL
Fully refundable
$106 nightly
The price is $118 total per night from Jul 9 to Jul 10
$118 total
Jul 9 - Jul 10
Total with taxes and fees
8.4/10 Very Good! (449 reviews)
"We were very pleased with our stay here. Staff were helpful and our room was great!"

Reviewed on Jun 27, 2026

Comfort Inn & Suites Greenville I-70
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Jul 6 to Jul 7
$72 total
Jul 6 - Jul 7
Total with taxes and fees
8/10 Very Good! (812 reviews)
"Wasn’t a bad stay, room wasn’t up to par with prior reviews though. Beds were fairly comfortable but nothing to write home to mom about."

Reviewed on Jun 30, 2026

Super 8 by Wyndham Greenville
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

2.5 out of 5
1731 S State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Jul 5 to Jul 6
$68 total
Jul 5 - Jul 6
Total with taxes and fees
7.4/10 Good! (587 reviews)
"The room was very clean and spacious for what we needed."

Reviewed on Jun 15, 2026

SureStay Hotel by Best Western Greenville
See all 70 properties in Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Greenville Vacation Packages

Greenville Essential Information

Language
English
Currency
U.S dollars
Population
6,700
Max Temp Winter
40ºF
Max Temp Summer
80ºF

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Frequently asked questions

How much does a Greenville vacation package cost?
Offering great value package deals from $332 on Expedia, you'll be pleasantly surprised at how much a vacation to Greenville costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Greenville?
If you're looking to score a cheap Greenville vacation package, consider visiting in January, March and December. You'll typically find lower prices on hotels and airfares during these months — perfect for travelers wishing to save money.
How many days is enough for Greenville?
Generally, a handful of days is enough to visit the major attractions during your Greenville vacation. However, if you want to have some time to unwind or take day tours, consider extending your itinerary.
How to find the best Greenville package deals?
Use Expedia's handy filters to find some great Greenville package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Greenville package deals in the off-season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Greenville vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll usually get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Greenville vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Greenville?
Enjoy incredible discounts by booking your flights in advance with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Greenville escape.
Does Expedia offer Book Now, Pay Later Greenville vacation packages?
If you're like us, you love exploring new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Greenville vacation over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.