Guadalupe County Vacations & Trips from $412
Book a Hotel + Flight or Car together to unlock savings
Photo by Kate Cadwell
Your Guadalupe County Vacation
Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.
Top destinations in Guadalupe County
Santa Rosa
Vaughn
The Latest Guadalupe County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Motel 6 Espanola, NM
Price was $499, price is now $474 per person
$474
per person
Apr 30 - May 3
found 17 hours ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Santa Fe (SAF)
6.4/10 (515 reviews)
One of the cleanest motels I’ve been in a long time. The water was hot. It was good and they provided coffee. I will definitely stay here again.
Reviewed on Sep 30, 2025
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Price was $871, price is now $848 per person
$848
per person
May 22 - May 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Santa Fe (SAF)
8.8/10 Excellent! (734 reviews)
Room was clean, staff was friendly. Breakfast was excellent.
Reviewed on Feb 25, 2026
Find the Best Guadalupe County Vacation Packages
Guadalupe County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Albuquerque Intl. Sunport Airport (ABQ) |
Top Sights | Blue Hole, Santa Rosa Lake State Park and Blue Hole |
Guadalupe County Hotel Deals
La Quinta Inn & Suites by Wyndham Santa Rosa
2277 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $164 total per night from Mar 8 to Mar 9
$164 total
Mar 8 - Mar 9
Total with taxes and fees
9.2/10 Wonderful! (1,477 reviews)
Oo
Reviewed on Feb 25, 2026
Super 8 by Wyndham Santa Rosa
2075 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Mar 5 to Mar 6
$81 total
Mar 5 - Mar 6
Total with taxes and fees
7.8/10 Good! (1,000 reviews)
Nice overnight stop
Reviewed on Feb 19, 2026
Comfort Inn Santa Rosa on Route 66
2524 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Mar 1 to Mar 2
$119 total
Mar 1 - Mar 2
Total with taxes and fees
8.4/10 Very Good! (1,001 reviews)
Very nice
Reviewed on Feb 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
Other vacations you might like
- Top cities in Guadalupe County
- Vacations and getaways similar to Guadalupe County
- Best vacation destinations by month
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.