Name: Comfort Inn Santa Rosa on Route 66
Price range: $105 total
Rating: 8.4

Your Guadalupe County Vacation

Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.

Top destinations in Guadalupe County

Panorama of a severe thunderstorm over the Black Mesa Park at the border of Oklahoma and New Mexico

The Latest Guadalupe County Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Ohkay Casino Resort Hotel

$467

per person

Aug 14 - Aug 17

found 14 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Santa Fe (SAF)

8/10 Very Good! (831 reviews)

Great hotel room, very clean and quiet!

Reviewed on May 29, 2026

The Inn at the Delta

$496

per person

Aug 14 - Aug 17

found 14 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Santa Fe (SAF)

9.4/10 Exceptional! (1,004 reviews)

A beautiful place to stay. The grounds are a mini botanical garden and the room was spacious and beautifully furnished.

Reviewed on May 24, 2026

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

$1,415

per person

Jul 20 - Jul 27

found 1 day ago

Roundtrip non-stop flight included

Washington (IAD) to Santa Fe (SAF)

8.8/10 Excellent! (780 reviews)

Would not give me a receipt.

Reviewed on May 25, 2026

Motel 6 Espanola, NM

$467

per person

Aug 14 - Aug 17

found 14 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Santa Fe (SAF)

6.4/10 (529 reviews)

Parking and entry were odd.

Reviewed on May 26, 2026

Hampton Inn & Suites Los Alamos White Rock

$566

per person

Aug 14 - Aug 17

found 14 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Santa Fe (SAF)

9/10 Wonderful! (714 reviews)

There was a funky smell to the room one night and they offered to bring up air freshener. It cleared by morning. Our tub didn’t feel particularly safe for showers. The tub sloped and there wasn’t much grippy coating left on the bottom for balance on a slippery tub bottom. Breakfast was ok but the ice machine was wicked loud if you sat by it.

Reviewed on May 5, 2026

Find the Best Guadalupe County Vacation Packages

Guadalupe County Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Albuquerque Intl. Sunport Airport (ABQ)
Top Sights	Blue Hole, Santa Rosa Lake State Park and Blue Hole

Guadalupe County Hotel Deals

La Quinta Inn & Suites by Wyndham Santa Rosa

2277 Historic Route 66 Santa Rosa NM

Fully refundableReserve now, pay when you stay

$130 nightly

$147 total

May 31 - Jun 1

Total with taxes and fees

9.2/10 Wonderful! (1,514 reviews)

"Hotel is easy to find from the highway. The beds were so comfortable! Breakfast was your average hotel free breakfast but it was enough to get us started. If I had one complaint it would be that the parking lot is quite small, especially if there are several vehicles with trailers in the lot."

Reviewed on May 30, 2026

Days Inn & Suites by Wyndham Santa Rosa

2255 Historic Route 66 Santa Rosa NM

Fully refundableReserve now, pay when you stay

$96 nightly

$109 total

Jun 14 - Jun 15

Total with taxes and fees

8.6/10 Excellent! (649 reviews)

"I want give a shoutout to the staff for being very helpful when I was to blame for a problematic booking through a 3rd party. I would recommend and stay there again as I travel that route frequently."

Reviewed on May 25, 2026

Comfort Inn Santa Rosa on Route 66

2524 Historic Route 66 Santa Rosa NM

Fully refundable

$93 nightly

$105 total

Jun 21 - Jun 22

Total with taxes and fees

8.4/10 Very Good! (1,008 reviews)

"The rooms were clean. Great breakfast, maybe one of the better ones I’ve been to. Friendly helpful staff who went above and beyond to help us out with a difficult situation. Plenty of parking. The pool looked nice although we didn’t use it."

Reviewed on May 29, 2026

See all 26 properties in Guadalupe County

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.