Guadalupe County Vacations & Trips from $538

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Your Guadalupe County Vacation

Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.

Top destinations in Guadalupe County

The Latest Guadalupe County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Ohkay Casino Resort Hotel
Wingate by Wyndham Los Alamos
The Inn at the Delta
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Historic Plaza Hotel

Find the Best Guadalupe County Vacation Packages

Guadalupe County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Albuquerque Intl. Sunport Airport (ABQ)
Top Sights
Blue Hole, Santa Rosa Lake State Park and Blue Hole

Guadalupe County Hotel Deals

La Quinta Inn & Suites by Wyndham Santa Rosa

La Quinta Inn & Suites by Wyndham Santa Rosa

3 out of 5
2277 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $157 total per night from Jul 19 to Jul 20
$157 total
Jul 19 - Jul 20
Total with taxes and fees
9.2/10 Wonderful! (1,536 reviews)
"Nice stay"

Reviewed on Jul 14, 2026

La Quinta Inn & Suites by Wyndham Santa Rosa
Hotel Blue 66, BW Signature Collection

Hotel Blue 66, BW Signature Collection

2.5 out of 5
2533 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $135 total per night from Jul 21 to Jul 22
$135 total
Jul 21 - Jul 22
Total with taxes and fees
8.4/10 Very Good! (358 reviews)
"Excellent service Nanci was very helpful in sorting out my booking mistakes can’t recommend enough and looking forward to my next stay there"

Reviewed on Jul 13, 2026

Hotel Blue 66, BW Signature Collection
Super 8 by Wyndham Santa Rosa

Super 8 by Wyndham Santa Rosa

2 out of 5
2075 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from Jul 16 to Jul 17
$90 total
Jul 16 - Jul 17
Total with taxes and fees
7.8/10 Good! (1,013 reviews)
"The beds were comfortable enough. The room was very hot when we got inside and the cooling system was tripped. It took a while to figure it out and cool down the room. We woke early for breakfast and there was a big coffee maker with a sign it was broken. There was a cheap 10 cup machine brought ..."

Reviewed on Jul 15, 2026

Super 8 by Wyndham Santa Rosa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Guadalupe County attractions

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.