Historic Southwest Vacations from $565

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Photo by Sara Crotts

Your Historic Southwest Vacation

Book a Historic Southwest vacation package and immerse yourself in the rhythm and vibe of this interesting neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is having a great time. When it's time to head out and explore, you'll find lots of big-name attractions nearby including Mayo Civic Center, Apache Mall and Rochester Recreation Center. Visit one, two or all during your trip to Historic Southwest. Stop dreaming and start doing. When it's time to book your next vacation to Historic Southwest, Expedia is here to help.

The Latest Historic Southwest Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
Downtown Rochester
Price was $674, price is now $565 per person
$565
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boise (BOI) to Rochester (RST)
8.8/10 Excellent! (815 reviews)
I love that there is no carpeting in the rooms. The handicapped bathroom is amazing.

Reviewed on Aug 28, 2025

Aspen Select

Aspen Select

3.5 out of 5
Price was $688, price is now $574 per person
$574
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boise (BOI) to Rochester (RST)
8.4/10 Very Good! (1,004 reviews)
This property is close to my destination and I like that. Parking is very tight and dark, it makes a person feels uncomfortable.

Reviewed on Aug 27, 2025

Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center

3 out of 5
Price was $680, price is now $577 per person
$577
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boise (BOI) to Rochester (RST)
9/10 Wonderful! (480 reviews)
The front desk gal during check-in was excellent. She was friendly, courteous, and efficient. I stay here for my annual appointment at Mayo for many reasons, but really appreciate a friendly smile when I arrive.

Reviewed on Aug 25, 2025

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Kutzky Park
Price was $672, price is now $575 per person
$575
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boise (BOI) to Rochester (RST)
9.2/10 Wonderful! (445 reviews)
We had a trailer and the night staff was extremely helpful in providing us on-site parking.

Reviewed on Aug 24, 2025

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

3 out of 5
Downtown Rochester
Price was $879, price is now $765 per person
$765
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boise (BOI) to Rochester (RST)
9.2/10 Wonderful! (159 reviews)
Great spacious apartments for long stay.

Reviewed on Aug 25, 2025

Where to stay in Historic Southwest

Find the best Historic Southwest areas and neighborhoods for the activities you enjoy most. Learn more about Historic Southwest
Rochester showing skyline and a city

Downtown Rochester

3 out of top 10 points of interest in this area
4.5/5(250 area reviews)

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Find hotels in Downtown Rochester

Historic Southwest Hotel Deals

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway, Rochester, MN
Fully refundable
$80 nightly
The price is $92 total per night from Sep 12 to Sep 13
$92 total
Sep 12 - Sep 13
Total with taxes and fees
8.8/10 Excellent! (814 reviews)
"Generally, we found the staff at Mayo Clinic and others met in Rochester very friendly and helpful. The Indigo hotel staff not so much."

Reviewed on Aug 18, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $142 total per night from Aug 30 to Aug 31
$142 total
Aug 30 - Aug 31
Total with taxes and fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway, Rochester, MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Sep 5 to Sep 6
$136 total
Sep 5 - Sep 6
Total with taxes and fees
Hilton Garden Inn Rochester Downtown, MN
See all 361 properties in Historic Southwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Historic Southwest

Soldier Field Park

Soldiers Field Veterans Memorial

You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.

Soldiers Field Veterans Memorial

Plummer House

Find out about the history of Rochester with a stop at Plummer House. Attend a sporting event or visit the shops in this family-friendly area.

Plummer House

Mayo Clinic

Though Mayo Clinic might be what brings you to town, perhaps you'll have a chance to explore more of Rochester while you are here.

Mayo Clinic
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.