Plan your trip

A wooden boardwalk leading to a beach with a palm tree and ocean in the background.

Search Guest Houses in Isabela

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

  • Check prices for these dates

    Check prices for these dates, December 15 – 16, 2026

    View in a map

    Our top choices for Isabela guest houses

    1. Medusas Hostel

    A beach with a sandy path leading to the water, surrounded by greenery and palm trees.

    2. Luna @ iLSognatore · A Little Italy in the Tropics

    A patio area with a mosaic floor, a round table with four chairs, and a grill station.

    3. Sunset Cliff - Cozy 2-bedrooms guest house in adorable Aguadilla - Ocean View

    View from main gate

    4. Rincon View Suites

    A modern two-story house with a swimming pool and outdoor seating.

    5. Casa Patriota

    A neatly made bed with a headboard, two bedside tables with lamps, and a framed picture on the wall.

    6. Red Flamboyan Guesthouse

    A rooftop terrace with white lounge chairs, a small table, and a string of lights.

    7. Caño Tiburones Guest House

    A hotel room with a bed, a TV, a desk, a chair, a lamp, a painting, and a view of the outside.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

    View all properties

    Learn more about Isabela

    Surf-battered beaches and lush forests beckon adventurers to this northwestern coastal gem. Hike to hidden waterfalls, explore caves at Guajataca Forest Reserve, or catch waves at Jobos Beach's world-class breaks.

    See all hotels in Isabela

    A wooden boardwalk leading to a beach with a palm tree and ocean in the background.

    Top reviews in Isabela

    Red Flamboyan Guesthouse

    A rooftop terrace with white lounge chairs, a small table, and a string of lights.

    Casa Patriota

    A neatly made bed with a headboard, two bedside tables with lamps, and a framed picture on the wall.

    Caño Tiburones Guest House

    A hotel room with a bed, a TV, a desk, a chair, a lamp, a painting, and a view of the outside.

    Medusas Hostel

    A beach with a sandy path leading to the water, surrounded by greenery and palm trees.

    Frequently Asked Questions

    What are the most popular guest houses in Isabela according to reviews?

    Islabella Guest House is a fantastic option for travelers seeking a memorable stay in Isabela, Puerto Rico. With inviting amenities like a shared refrigerator and a fully equipped kitchen, guests can easily prepare their favorite meals and enjoy them in the lovely yard. This property is great for those who appreciate convenience and a cozy feel while exploring the beauty of the island.

    What is the nightly rate for a guest house in Isabela?

    Rates for Isabela guest houses vary, but travelers can find great-value prices from $60 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Isabela guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.

    What's the difference between a Isabela guest house and a B&B?

    A guest house in Isabela is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

    Explore a world of travel with Expedia