Isola Vacations from $1,121

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Isola Vacation

Known for its rich history and spectacular views, Isola is a fantastic getaway destination. Book one of our Isola vacation packages and uncover all that this lively city has to offer. If a sightseeing tour is on the agenda during your trip to Isola, look around leading attractions like Cathedral of Syracuse, Temple of Apollo and Castello Eurialo. Expedia is here to help you escape your routine. Tailor your vacation to Isola to suit your style of travel, whatever that may be!

The Latest Isola vacation packages

Price found within the past 48 hours. Click for updated prices.
B&B Marranzano

B&B Marranzano

3 out of 5
Price was $1,486, price is now $1,121 per person
$1,121
per person
May 5 - May 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Catania (CTA)
8.2/10 Very Good! (77 reviews)
The property is beautiful , walking distance to everything Giardini Naxos has to offer. My only complaint was not having hot water all the time.

Reviewed on Sep 25, 2025

Hotel Metropole Taormina

Hotel Metropole Taormina

5 out of 5
Taormina City Centre
Save 100% on your flight
Price was $10,025, price is now $6,295 per person
$6,295
per person
May 18 - May 24
found 4 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Catania (CTA)
9.4/10 Exceptional! (263 reviews)
Lucia at the front desk was the best part of the stay. She was great.

Reviewed on Dec 27, 2025

Hotel Elios

Hotel Elios

3 out of 5
Price was $1,795, price is now $1,236 per person
$1,236
per person
May 5 - May 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Catania (CTA)
6.8/10 (26 reviews)
Very well located in Taormina with a beautiful panoramic view of Mount Etna.

Reviewed on Aug 4, 2019

Hotel Condor

Hotel Condor

3 out of 5
Price was $1,564, price is now $1,169 per person
$1,169
per person
May 5 - May 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Catania (CTA)
8.8/10 Excellent! (646 reviews)
Great place to stay. Very helpful staff.

Reviewed on Nov 3, 2025

Hotel Casa Adele

Hotel Casa Adele

3 out of 5
Price was $1,708, price is now $1,283 per person
$1,283
per person
May 5 - May 7
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Catania (CTA)
9.8/10 Exceptional! (132 reviews)
Beautiful property. Friendly staff

Reviewed on Jun 2, 2025

Don't see what you're looking for?
See all available trips from Columbus to Isola
View all trips

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Discover the most popular places to visit in Isola

Magnificent view

Lungomare di Ortigia

4.5/5(37 reviews)

You can take time to visit Lungomare di Ortigia during your travels to Syracuse. Wander the seaside in this culturally rich area.

Lungomare di Ortigia
Temple of Apollo featuring a ruin and heritage elements

Temple of Apollo

4.5/5(86 reviews)

Discover over 2,000 years of history when you visit the oldest Doric temple in Sicily.

Temple of Apollo

Greek Theatre of Syracuse

4.5/5(61 reviews)

You can learn about the history of Syracuse with a visit to Greek Theatre of Syracuse. Wander the seaside in this culturally rich area.

Greek Theatre of Syracuse

What to do in Isola

Siracusa: Ortygia Island Boat Tour with Grotto Visit

Siracusa: Ortygia Island Boat Tour with Grotto Visit

$29
per adult
Siracusa: Ortygia Island Boat Tour with Grotto Visit
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves

Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves

$35
per adult
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

$47
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
See all activities in Isola

Isola Hotel Deals

House with private tennis court, pool, 300m to the beach, WiFi, air conditioning

House with private tennis court, pool, 300m to the beach, WiFi, air conditioning

Syrakus Sizilien
9/10 Wonderful! (31 reviews)
A great family villa. Lively hosts, Enzo was very helpful with any queries and Sebastian brought us some lovely fruit and pastries a couple of times. Well equipt villa with all required, kitchen facilities were good, plenty of towels for all. The bathing facilities could be improved ( showers). Pool ...

Reviewed on Oct 13, 2025

Get rates
House with private tennis court, pool, 300m to the beach, WiFi, air conditioning
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

4 out of 5
Via Vittorio Veneto 93 Syracuse SR
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $229 total per night from Mar 16 to Mar 17
$229 total
Mar 16 - Mar 17
Total with taxes and fees
9.6/10 Exceptional! (929 reviews)
Sonia who runs the dining room is amazing very helpful. She even remembers what you ordered the day before for breakfast.

Reviewed on Mar 4, 2026

Algila' Ortigia Charme Hotel
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $228 total per night from Mar 15 to Mar 16
$228 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (580 reviews)
Great location and beautiful scenery

Reviewed on Mar 11, 2026

Grand Hotel Ortigia Siracusa
See all 3,650 properties in Isola
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isola Vacation Packages

Isola Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Top Sights
Greek Theatre of Syracuse, Arenella Beach and Cathedral of Syracuse

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does an Isola vacation package cost?
Offering excellent value package deals from $1,121 on Expedia, you'll be surprised at how little a vacation to Isola costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Isola?
November, December and January are the best times to search for cheap Isola vacation packages. Opting to travel in quieter months means you can typically find reduced prices on accommodations and flights.
How many days is enough for Isola?
The ideal duration for your Isola vacation depends on what you'd like to see. Generally, a few days to a week will give you time to hit all the major sights and discover some hidden gems along the way.
How to find the best Isola package deals?
Landing a cheap Isola package deal is a cinch with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Isola package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book an Isola vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging hotels and flights separately. Better still, you can customize your Isola trip to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Isola?
Enjoy amazing discounts by booking your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Isola vacation.
How to plan a trip to Isola?

  1. Choose the right time to travel: Your schedule, favorite season and the type of weather you enjoy can all impact your decision on when to travel to Isola.
  2. Set a budget: Consider costs like flights, food and transportation when working out how much to set aside for your trip to Isola. Then, select a property that suits your budget, whether that's a wallet-friendly option or a high-end getaway.
  3. Organize your Isola getaway with our trip planning tool: Look for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to Isola together.
  4. Decide how long to go for: Now that you know more about Isola, you can work out the perfect length of your vacation. Pull together a rough itinerary and give yourself enough time for all the things you want to do.
  5. Bundle your airfare and accommodations: After you've settled on your dates and duration, book the ideal Isola vacation package for you.
  6. Book any day trips or activities: Here's the fun part — locking in everything you want to do and see. Browse some of the top things to do in Isola and reserve your tickets in advance to save time (and maybe some dollars too!).

Does Expedia offer Book Now, Pay Later Isola vacation packages?
Your Isola getaway is meant to be a relaxing escape from your busy life, not a source of money worries. So to give you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.