Isola Vacations from $1,149

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Your Isola Vacation

Known for its rich history and spectacular views, Isola is a fantastic getaway destination. Book one of our Isola vacation packages and uncover all that this lively city has to offer. If a sightseeing tour is on the agenda during your trip to Isola, look around leading attractions like Cathedral of Syracuse, Temple of Apollo and Castello Eurialo. Expedia is here to help you escape your routine. Tailor your vacation to Isola to suit your style of travel, whatever that may be!

The Latest Isola vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Continental
Hotel Elios
Hotel Palladio
Hotel Villa Paradiso
Panoramic Hotel
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Discover the most popular places to visit in Isola

What to do in Isola

Isola Hotel Deals

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

4 out of 5
Via Vittorio Veneto 93 Syracuse SR
Fully refundableReserve now, pay when you stay
$358 nightly
The price is $405 total per night from May 17 to May 18
$405 total
May 17 - May 18
Total with taxes and fees
9.6/10 Exceptional! (952 reviews)
The room was comfortable, spacious and quiet. We had a second small room as a sitting area. We had a small Juliette balcony overlooking the waterfront. Nice bathroom. Very central location. Coffee in room wasn’t that great compared to other hotels in this price point. Instant coffee. Great restaurant ...

Reviewed on May 10, 2026

Algila' Ortigia Charme Hotel
Mangia's Brucoli, Sicily, Autograph Collection

Mangia's Brucoli, Sicily, Autograph Collection

5 out of 5
Contrada Gisira 1 Augusta SR
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $216 total per night from Jun 7 to Jun 8
$216 total
Jun 7 - Jun 8
Total with taxes and fees
8.6/10 Excellent! (125 reviews)
Nice location, very friendly staff, Breakfast was especially good

Reviewed on May 10, 2026

Mangia's Brucoli, Sicily, Autograph Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $348 total per night from May 21 to May 22
$348 total
May 21 - May 22
Total with taxes and fees
Grand Hotel Ortigia Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isola Vacation Packages

Isola Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Top Sights
Greek Theatre of Syracuse, Arenella Beach and Cathedral of Syracuse

More vacations you might like

Frequently asked questions

How much does an Isola vacation package cost?
Offering excellent value package deals from $1,149 on Expedia, you'll be surprised at how little a vacation to Isola costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Isola?
November, December and January are the best times to search for cheap Isola vacation packages. Opting to travel in quieter months means you can typically find reduced prices on accommodations and flights.
How many days is enough for Isola?
The ideal duration for your Isola vacation depends on what you'd like to see. Generally, a few days to a week will give you time to hit all the major sights and discover some hidden gems along the way.
How to find the best Isola package deals?
Landing a cheap Isola package deal is a cinch with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Isola package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book an Isola vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging hotels and flights separately. Better still, you can customize your Isola trip to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Isola?
Enjoy amazing discounts by booking your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Isola vacation.
How to plan a trip to Isola?

  1. Choose the right time to travel: Your schedule, favorite season and the type of weather you enjoy can all impact your decision on when to travel to Isola.
  2. Set a budget: Consider costs like flights, food and transportation when working out how much to set aside for your trip to Isola. Then, select a property that suits your budget, whether that's a wallet-friendly option or a high-end getaway.
  3. Organize your Isola getaway with our trip planning tool: Look for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to Isola together.
  4. Decide how long to go for: Now that you know more about Isola, you can work out the perfect length of your vacation. Pull together a rough itinerary and give yourself enough time for all the things you want to do.
  5. Bundle your airfare and accommodations: After you've settled on your dates and duration, book the ideal Isola vacation package for you.
  6. Book any day trips or activities: Here's the fun part — locking in everything you want to do and see. Browse some of the top things to do in Isola and reserve your tickets in advance to save time (and maybe some dollars too!).

Does Expedia offer Book Now, Pay Later Isola vacation packages?
Your Isola getaway is meant to be a relaxing escape from your busy life, not a source of money worries. So to give you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.