Isolotto Vacations from $641

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

The Latest Isolotto Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Eurostars Florence Boutique
Aurum Uffizi
Villa Cora
Dimora Palanca Boutique & SPA
Aurum Firenze

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72, Florence, FI
Fully refundable
$106 nightly
The price is $134 total per night from Nov 2 to Nov 3
$134 total
Nov 2 - Nov 3
Total with taxes and fees
8.8/10 Excellent! (1,229 reviews)
"Next to tram stop. Near train station."

Reviewed on Oct 3, 2025

The Social Hub Florence Lavagnini
Hotel Machiavelli Palace

Hotel Machiavelli Palace

3 out of 5
Via Nazionale 10, Florence, FI
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $107 total per night from Nov 2 to Nov 3
$107 total
Nov 2 - Nov 3
Total with taxes and fees
8.4/10 Very Good! (95 reviews)
"Place was in a busy area which was convenient, not so quiet, bathroom is very small. Staff were very nice and breakfast is a bonus."

Reviewed on Sep 27, 2025

Hotel Machiavelli Palace
c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Via Luigi Alamanni 3, Florence, FI
$187 nightly
The price is $223 total per night from Nov 2 to Nov 3
$223 total
Nov 2 - Nov 3
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"Best, tram and station and all the attractions just walkable"

Reviewed on Sep 26, 2025

c-hotels Ambasciatori
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.