Isolotto Vacations from $831

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Your Isolotto Vacation

Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.

The Latest Isolotto Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze
Aurum Uffizi
Grand Hotel Cavour
Hotel La Scaletta Al Ponte Vecchio
Hotel Villani

Where to stay in Isolotto

Find the best Isolotto areas and neighborhoods for the activities you enjoy most. Learn more about Isolotto

Isolotto Hotel Deals

IQ Hotel Firenze

IQ Hotel Firenze

4 out of 5
Via Camillo Cavour, 88 Florence FI
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $163 total per night from Mar 5 to Mar 6
$163 total
Mar 5 - Mar 6
Total with taxes and fees
9.6/10 Exceptional! (1,172 reviews)
Yes to all

Reviewed on Feb 25, 2026

IQ Hotel Firenze
c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Via Luigi Alamanni 3 Florence FI
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $155 total per night from Mar 1 to Mar 2
$155 total
Mar 1 - Mar 2
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
It was amazing and clean and really really perfect

Reviewed on Feb 17, 2026

c-hotels Ambasciatori
Hotel Delle Nazioni

Hotel Delle Nazioni

3 out of 5
Via Luigi Alamanni, 15 Florence FI
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $126 total per night from Mar 3 to Mar 4
$126 total
Mar 3 - Mar 4
Total with taxes and fees
8.4/10 Very Good! (1,008 reviews)
The staff was extremely helpful. Much appreciated. The location was great, right across from the Central Station, so convenient. I would, for sure, recommend this hotel for visiting Florence

Reviewed on Feb 18, 2026

Hotel Delle Nazioni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Isolotto

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.