Title: Jeff-Vander-Lou Vacation Packages 2026 from $355 | Expedia.com

[Hotels in Jeff-Vander-Lou](https://expedia.com/Jeff-Vander-Lou-St-Louis-Hotels.0-n553248635976470399-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.com/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.com/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Car Rentals in Jeff-Vander-Lou](https://expedia.com/Car-Rentals-In-Jeff-Vander-Lou.d553248635976470399.Car-Rental-Guide)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium)

# Jeff-Vander-Lou Vacations from $355

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

## Your Jeff-Vander-Lou Vacation

Jeff-Vander-Lou is calling! Whatever type of escape you have in mind, you can see and experience the best of this neighborhood with a Jeff-Vander-Lou vacation package. Some popular nearby attractions to visit during your trip to Jeff-Vander-Lou include [Busch Stadium](https://www.expedia.com/Busch-Stadium-Downtown-St-Louis.d502872.Vacation-Attraction), [Gateway Arch](https://www.expedia.com/Gateway-Arch-Downtown-St-Louis.d502855.Vacation-Attraction) and [Dome at America’s Center](https://www.expedia.com/Dome-At-Americas-Center-Downtown-St-Louis.d6058090.Vacation-Attraction). Stop daydreaming and start doing. When it's time to lock in your next vacation to Jeff-Vander-Lou, Expedia is here to help.

## The Latest Jeff-Vander-Lou Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Wildwood Hotel

$355

per person

Apr 24 - Apr 27

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

9.2/10 Wonderful! (1,626 reviews)

Place was nice. Had handicap room. No living room type chair, just computer chair. Hot tub was like a four-seater and only two mild jets. Main pool half size of most and a nly went from 3 feet to 4 feet. Very small. Breakfast was excellent.

Reviewed on Mar 11, 2026

![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Save 100% on your flight

$442

per person

Apr 24 - Apr 27

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.8/10 Excellent! (1,060 reviews)

The property was beautiful and unique. The food was a disappointment. Unfortunately it was just too greasy for us.

Reviewed on Mar 6, 2026

![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Home2 Suites by Hilton St. Louis Downtown

Downtown West

Save 100% on your flight

$471

per person

Apr 21 - Apr 25

found 1 day ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

8/10 Very Good! (690 reviews)

We booked this hotel for the vicinity to the Dome and for the known chain name. There were several issues during our stay that i think were significant due to the fact the hotel was sold out for the weekend: Parking is only valet and there was only one person working valet, so, could take up to 45min to get the vehicle 3 elevators but only 1 was working We didnt have hot water the first morning we showered The handle on our bathroom drawer was broken, the piece put in the drawer, when we arrived There were dirty dishes from the previous guest in the dishwasher, which caused the room to smell bad

Reviewed on Mar 9, 2026

![Spacious 3-Bedroom with King Bed](https://images.trvl-media.com/lodging/110000000/109680000/109680000/109679988/f2203ae1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Spacious 3-Bedroom with King Bed

Central West End

Save 100% on your flight

$1,144

per person

May 21 - May 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.8/10 Excellent! (11 reviews)

Clean room nice area

Reviewed on Feb 1, 2026

![Hotel Saint Louis, Autograph Collection](https://images.trvl-media.com/lodging/28000000/27480000/27478600/27478599/8a12cc18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Saint Louis, Autograph Collection

Downtown St. Louis

Save 100% on your flight

$687

per person

Apr 21 - Apr 25

found 1 day ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

8.8/10 Excellent! (476 reviews)

Good location, sheets were dirty and bathroom shower was also covered in someone else’s hair.

Reviewed on Mar 10, 2026

## Where to stay in Jeff-Vander-Lou

Find the best Jeff-Vander-Lou areas and neighborhoods for the activities you enjoy most. [Learn more about Jeff-Vander-Lou](https://expedia.com/St-Louis-Jeff-Vander-Lou.dx553248635976470399)

![Meeting of the Waters Fountain showing a statue or sculpture and a fountain](https://images.trvl-media.com/place/553248621555612576/762dd336-6149-4976-83d5-b2545c390515.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown St. Louis

3 out of top 10 points of interest in this area

4/5(4,004 area reviews)

 Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River. 

[Find hotel + flight trips in Downtown St. Louis](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20St.%20Louis&DestID=800136&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Clayton

1 out of top 10 points of interest in this area

 Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station. 

[Find hotel + flight trips in Clayton](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Clayton&DestID=6058846&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![St. Louis](https://images.trvl-media.com/place/6272/26979a45-e5a8-4066-9ddd-1ba301b4bd4a.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Berkeley

 Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town. 

[Find hotel + flight trips in Berkeley](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Berkeley&DestID=6272&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Love this hotel.](https://images.trvl-media.com/place/3284/7d953ffd-a093-422e-8101-35af3b9eb6fc.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown West

3 out of top 10 points of interest in this area

 If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing. 

[Find hotel + flight trips in Downtown West](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20West&DestID=553248635976473134&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Central West End

4.5/5(450 area reviews)

 Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis. 

[Find hotel + flight trips in Central West End](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Central%20West%20End&DestID=6175135&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Jeff-Vander-Lou Hotel Deals

![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

$100 nightly

$116 total

Apr 12 - Apr 13

Total with taxes and fees

8.8/10 Excellent! (3,103 reviews)

This is an older property, but very clean, comfortable, spacious and convenient to downtown Clayton. Parking was convenient and free on the weekend. Breakfast was better than average, with chef-made omelets and waffles.

Reviewed on Mar 11, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true&regionId=553248635976470399)

![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

21C Museum Hotel St Louis 

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

$131 nightly

$153 total

Apr 5 - Apr 6

Total with taxes and fees

9/10 Wonderful! (1,648 reviews)

Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones.

Reviewed on Mar 11, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true&regionId=553248635976470399)

![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

$135 nightly

$158 total

Mar 16 - Mar 17

Total with taxes and fees

9.4/10 Exceptional! (3,362 reviews)

Very nice staff and great atmosphere. Quietest hotel room i have ever stayed in

Reviewed on Mar 10, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=546271&PinnedHotelID=546271&HadPinnedHotel=true&regionId=553248635976470399)

[See all 1,888 properties in Jeff-Vander-Lou](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&regionId=553248635976470399)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Jeff-Vander-Lou

![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game. 

[](https://expedia.com/St-Louis-Union-Station-Downtown-West.d502868.Vacation-Attraction)

![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game. 

[](https://expedia.com/Busch-Stadium-Downtown-St-Louis.d502872.Vacation-Attraction)

![Gateway Arch showing a city, a skyscraper and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

[](https://expedia.com/Gateway-Arch-Downtown-St-Louis.d502855.Vacation-Attraction)

### Things to do

![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Ghost Tour: Sinister Sins & Shadows

$24

per adult

[](https://expedia.com/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details)

![Lemp Haunted Neighborhood Walking Tour](https://mediaim.expedia.com/localexpert/1357747/a0055784-5adb-4f81-8c3e-b01a05d29286.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Lemp Haunted Neighborhood Walking Tour

$30

per adult

**84%** of travellers recommend

[](https://expedia.com/things-to-do/lemp-haunted-neighborhood-walking-tour.a1357747.activity-details)

![St. Louis Premium Driving Tour with Boat Ride & Arch](https://mediaim.expedia.com/localexpert/47712556/5e48de69-a78b-4315-bccd-6ae9dafd98a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Premium Driving Tour with Boat Ride & Arch

$174

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/st-louis-premium-driving-tour-with-boat-ride-arch.a47712556.activity-details)

[See all activities in St. Louis](https://expedia.com/things-to-do/search?rid=553248635976470399)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.