La Mesilla Vacations from $363

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Your La Mesilla Vacation

History, cuisine, art and more … There's so much to discover with a La Mesilla vacation package. And with the ability to customize your city adventure, you know it'll be one that's hard to forget. When it's time to get out and explore, be sure to include Tesuque Peak Trail and Bond House Museum on the itinerary for your trip to La Mesilla. Whoever you're going away with and whatever you plan to spend, your ultimate La Mesilla vacation is just a few clicks away with Expedia.

The Latest La Mesilla vacation packages

Price found within the past 48 hours. Click for updated prices.
Rodeway Inn

Rodeway Inn

2 out of 5
Price was $394, price is now $363 per person
$363
per person
Sep 25 - Sep 28
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
6.2/10 (450 reviews)
The young woman who checked us in was very friendly

Reviewed on Aug 18, 2025

Ohkay Casino Resort Hotel

Ohkay Casino Resort Hotel

2.5 out of 5
Price was $557, price is now $432 per person
$432
per person
Oct 6 - Oct 10
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
8/10 Very Good! (764 reviews)
I LIKED THE crab leg plate a bit not too meaty, should've gotten a burger. The room bed wise was good but noisy children next room too loud because of thin walls.

Reviewed on Aug 19, 2025

Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

2.5 out of 5
Price was $815, price is now $700 per person
$700
per person
Oct 7 - Oct 11
found 1 day ago
Roundtrip non-stop flight included
Tampa (TPA) to Santa Fe (SAF)
8/10 Very Good! (543 reviews)
We stay at this property because it is close to our grandchildren. There seems to be construction going on in the hotel. Our room was very spartan and didn't seem finished. There was no place to hang clothes other than a few hooks on the wall. The room didn't have a full bathroom - a wash basin was situated in the entry hall and the rest of what should have been a bathroom was located across that entry hall. For this we paid a premium price. I am looking for some other place, near our grandchildren, to stay.

Reviewed on Aug 11, 2025

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

2.5 out of 5
Price was $489, price is now $442 per person
$442
per person
Nov 6 - Nov 9
found 22 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Santa Fe (SAF)
8.8/10 Excellent! (705 reviews)
This was a convenient place to stay and call home for 4 days right outside of Los Alamos. The staff was friendly and helpful when we needed extra supplies.

Reviewed on Aug 23, 2025

Motel 6 Espanola, NM

Motel 6 Espanola, NM

2 out of 5
Price was $441, price is now $414 per person
$414
per person
Nov 6 - Nov 9
found 22 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to Santa Fe (SAF)
6.4/10 (504 reviews)
New management is awesome

Reviewed on Jul 24, 2025

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Discover the most popular places to visit in La Mesilla

Puye Cliff Dwellings

Puye Cliff Dwellings

Learn about the Pueblo Indians from these cave dwellings carved into the side of a cliff and atop a large mesa in the Rio Grande Valley.

Puye Cliff Dwellings

Tesuque Peak Trail

You can take time to visit Tesuque Peak Trail during your travels to Espanola. Check out the casinos and top-notch restaurants in this relaxing area.

Tesuque Peak Trail

La Mesilla Hotel Deals

Cities Of Gold Casino

Cities Of Gold Casino

3 out of 5
10-A Cities of Gold Road, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Sep 25 to Sep 26
$96 total
Sep 25 - Sep 26
Total with taxes and fees
8/10 Very Good! (1,048 reviews)
"Proximity to downtown Santa Fe"

Reviewed on Aug 22, 2025

Cities Of Gold Casino
Hotel Glorieta

Hotel Glorieta

3.5 out of 5
750 N. St Francis Dr, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $184 total per night from Sep 10 to Sep 11
$184 total
Sep 10 - Sep 11
Total with taxes and fees
7.8/10 Good! (1,008 reviews)
"The property itself is beautiful and the staff were nice. The hotel changed names and owners since I booked, and they were in the process of making some updates. The restaurant was closed, but I do think having a few bagel or muffin options on the morning would be a nice touch since there’s nothing ..."

Reviewed on Aug 23, 2025

Hotel Glorieta
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

4 out of 5
20 Buffalo Thunder Trl, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $196 total per night from Sep 1 to Sep 2
$196 total
Sep 1 - Sep 2
Total with taxes and fees
8.4/10 Very Good! (1,002 reviews)
"Great accommodations"

Reviewed on Aug 20, 2025

Hilton Santa Fe Buffalo Thunder
See all 309 properties in La Mesilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a La Mesilla vacation package cost?
You can grab a vacation package to this popular destination from $363 on Expedia. But how much your vacation to La Mesilla costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to La Mesilla?
If you're hoping to score a cheap La Mesilla vacation package, consider visiting in February, November and December. You'll generally find better prices on accommodations and flights during these quieter months — perfect for budget-conscious travelers.
How many days is enough for La Mesilla?
With a well-organized travel plan, you can easily hit the top La Mesilla sights in a handful of days. But if you want to venture off the beaten track or go on day trips, consider booking your La Mesilla vacation for longer.
How to find the best La Mesilla package deals?
Use Expedia's handy filters to find some tempting La Mesilla package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for La Mesilla package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a La Mesilla vacation as a package?
You can enjoy significant savings on your La Mesilla retreat by booking a customized vacation package. Check the "Package" heading, then select your destination and travel dates to view the best flight and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to La Mesilla?
Land incredible bargains by booking your flights ahead of time with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for a spur-of-the-moment La Mesilla trip.
Does Expedia offer Book Now, Pay Later La Mesilla vacation packages?
If you're anything like us, you love exploring new places but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your La Mesilla trip over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.