
La Mesilla Vacations from $451
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your La Mesilla Vacation
History, cuisine, art and more … There's so much to discover with a La Mesilla vacation package. And with the ability to customize your city adventure, you know it'll be one that's hard to forget. When it's time to get out and explore, be sure to include Tesuque Peak Trail and Bond House Museum on the itinerary for your trip to La Mesilla. Whoever you're going away with and whatever you plan to spend, your ultimate La Mesilla vacation is just a few clicks away with Expedia.
The Latest La Mesilla vacation packages

Motel 6 Espanola, NM
Reviewed on Sep 30, 2025



Hampton Inn & Suites Los Alamos White Rock
Reviewed on Nov 18, 2025

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Reviewed on Nov 26, 2025
Discover the most popular places to visit in La Mesilla

Puye Cliff Dwellings
Learn about the Pueblo Indians from these cave dwellings carved into the side of a cliff and atop a large mesa in the Rio Grande Valley.
Tesuque Peak Trail
You can take time to visit Tesuque Peak Trail during your travels to Espanola. Check out the casinos and top-notch restaurants in this relaxing area.
La Mesilla Hotel Deals

Hilton Santa Fe Buffalo Thunder
Our room had an old desk chair that looked like it had been there since the hotel opened. The shower had hair in the drain and there was hair on the shower door and on the shower wall-YUCK!!!
Reviewed on Dec 1, 2025

Bishop's Lodge, Auberge Collection
Great location, Resort, amenities, excellent service and great restaurant chef!!!!!
Reviewed on Nov 16, 2025

Hotel Glorieta
W
Reviewed on Nov 28, 2025
Find the Best La Mesilla Vacation Packages
La Mesilla Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Santa Fe Municipal Airport (SAF) |
Population | 1,750 |
Top Sights | Tesuque Peak Trail, Puye Cliff Dwellings and Bond House Museum |



















