La Mesilla Vacations from $365

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Your La Mesilla Vacation

History, cuisine, art and more … There's so much to discover with a La Mesilla vacation package. And with the ability to customize your city adventure, you know it'll be one that's hard to forget. When it's time to get out and explore, be sure to include Tesuque Peak Trail and Bond House Museum on the itinerary for your trip to La Mesilla. Whoever you're going away with and whatever you plan to spend, your ultimate La Mesilla vacation is just a few clicks away with Expedia.

The Latest La Mesilla vacation packages

Price found within the past 48 hours. Click for updated prices.
Historic Plaza Hotel

Historic Plaza Hotel

2 out of 5
Price was $399, price is now $365 per person
$365
per person
Nov 20 - Nov 23
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Santa Fe (SAF)
8.6/10 Excellent! (110 reviews)
Room was clean and quiet. Everything worked properly. Beautiful historic hotel with nice staff.

Reviewed on Oct 6, 2025

The Inn at the Delta

The Inn at the Delta

3 out of 5
Price was $1,005, price is now $795 per person
$795
per person
Dec 30 - Jan 5
found 4 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Santa Fe (SAF)
9.4/10 Exceptional! (1,001 reviews)
Didn't use the fireplace. The room was beautiful. There was no information about any amenities if there were any. Some of the ads & reviews acted like there was? Guests should be warned 27 steps up a steep stairway to room. We were ok but some may not be.

Reviewed on Sep 25, 2025

Days Inn by Wyndham Espanola

Days Inn by Wyndham Espanola

2 out of 5
Price was $614, price is now $513 per person
$513
per person
Dec 30 - Jan 5
found 4 hours ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
5.8/10 (576 reviews)
There's a reason it appears less expensive than surrounding hotels. Apparently foregoing some housekeeping and repair/maintenance.

Reviewed on Oct 8, 2025

Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

2.5 out of 5
Price was $562, price is now $474 per person
$474
per person
Nov 27 - Dec 1
found 8 hours ago
Roundtrip flight included
Denver (DEN) to Santa Fe (SAF)
8/10 Very Good! (547 reviews)
Was great minus very small parking lot. Didn’t have fresh towels, drains didn’t drain well, no shampoo

Reviewed on Sep 21, 2025

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

2.5 out of 5
Price was $498, price is now $441 per person
$441
per person
Nov 27 - Dec 1
found 8 hours ago
Roundtrip flight included
Denver (DEN) to Santa Fe (SAF)
8.8/10 Excellent! (717 reviews)
Staff were exceptional and cleanness

Reviewed on Oct 14, 2025

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Discover the most popular places to visit in La Mesilla

Puye Cliff Dwellings

Puye Cliff Dwellings

4.5/5(66 reviews)

Learn about the Pueblo Indians from these cave dwellings carved into the side of a cliff and atop a large mesa in the Rio Grande Valley.

Puye Cliff Dwellings

Tesuque Peak Trail

You can take time to visit Tesuque Peak Trail during your travels to Espanola. Check out the casinos and top-notch restaurants in this relaxing area.

Tesuque Peak Trail

La Mesilla Hotel Deals

Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

4 out of 5
20 Buffalo Thunder Trl, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from Oct 29 to Oct 30
$133 total
Oct 29 - Oct 30
Total with taxes and fees
8.4/10 Very Good! (1,021 reviews)
"Balcony was very quiet"

Reviewed on Oct 13, 2025

Hilton Santa Fe Buffalo Thunder
Cities Of Gold Casino

Cities Of Gold Casino

3 out of 5
10-A Cities of Gold Road, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Nov 13 to Nov 14
$96 total
Nov 13 - Nov 14
Total with taxes and fees
8/10 Very Good! (1,065 reviews)
"Not bad coffee was great"

Reviewed on Oct 13, 2025

Cities Of Gold Casino
Hotel Glorieta

Hotel Glorieta

3.5 out of 5
750 N. St Francis Dr, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $143 total per night from Nov 13 to Nov 14
$143 total
Nov 13 - Nov 14
Total with taxes and fees
Hotel Glorieta
See all 308 properties in La Mesilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

La Mesilla Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Santa Fe Municipal Airport (SAF)
Population
1,750
Top Sights
Tesuque Peak Trail, Puye Cliff Dwellings and Bond House Museum

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Frequently asked questions

How much does a La Mesilla vacation package cost?
You can grab a vacation package to this popular destination from $365 on Expedia. But how much your vacation to La Mesilla costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to La Mesilla?
If you're hoping to score a cheap La Mesilla vacation package, consider visiting in February, November and December. You'll generally find better prices on accommodations and flights during these quieter months — perfect for budget-conscious travelers.
How many days is enough for La Mesilla?
With a well-organized travel plan, you can easily hit the top La Mesilla sights in a handful of days. But if you want to venture off the beaten track or go on day trips, consider booking your La Mesilla vacation for longer.
How to find the best La Mesilla package deals?
Use Expedia's handy filters to find some tempting La Mesilla package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for La Mesilla package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a La Mesilla vacation as a package?
You can enjoy significant savings on your La Mesilla retreat by booking a customized vacation package. Check the "Package" heading, then select your destination and travel dates to view the best flight and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to La Mesilla?
Land incredible bargains by booking your flights ahead of time with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for a spur-of-the-moment La Mesilla trip.
Does Expedia offer Book Now, Pay Later La Mesilla vacation packages?
If you're anything like us, you love exploring new places but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your La Mesilla trip over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.