Title: La Raya de Santa María Vacation Packages 2026 from $729 | Expedia.com

[La Raya de Santa María Travel Guide](https://expedia.com/La-Raya-De-Santa-Maria.dx829297289699811328)[Hotels in La Raya de Santa María](https://expedia.com/La-Raya-De-Santa-Maria-Hotels.d829297289699811328.Travel-Guide-Hotels)[Vacation Rentals in La Raya de Santa María](https://expedia.com/La-Raya-De-Santa-Maria-Vacation-Rentals.d829297289699811328.Travel-Guide-VacationRentals)[Car Rentals in La Raya de Santa María](https://expedia.com/Car-Rentals-In-La-Raya-De-Santa-Maria.d829297289699811328.Car-Rental-Guide)

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# La Raya de Santa María Vacations from $729

## Book a Hotel + Flight or Car together to unlock savings

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## The Latest La Raya de Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.

![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Mahogany Suites

$729

per person

Mar 8 - Mar 15

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

10/10 Exceptional! (1 review)

Excellent apartment on a golf resort. 5 Star.

Reviewed on Jan 28, 2026

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,023

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Location, amenities and staff were great.

Reviewed on Feb 3, 2026

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Panama

Bella Vista

$921

per person

Mar 8 - Mar 15

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (4,515 reviews)

The hotel is centrally located n Panama City from where one can easily access to other part of the city by a short taxi ride, Our hotel room is always kept very clean, and it is very spacious and takes plenty of sunshine. Bathroom is a decent size with a .modern shover and double sinks it is always kept very clean and spotless with clean towels which are daily changed. No reason to say 24 hours receptions, the receptionists are multi lingual and fluent in English also very friendly, helpful and professional. Hotel provides excellent and very delicious breakfast with a great diversity of food including vegetarian and vegan choices, In addition, there are two restaurants: 1\. Spanish Restaurant; 2, Ibiza Restaurant near the swimming pool. Both restaurants provides excellent and delicious meals with a reasonable price. We really like The Spanish Restaurant very much because the quality of the meals and food in this restaurant are very authentic and as good as Spanish food in Spain even better in some instances. Swimming pool is great and I believe in an olympic size swimming pool. Weekends it becomes relatively crowded and also locals participate with larger number than that of other days. I believe that Hotel Riu Plaza in Panama City is an excellent place to spent your vacation.

Reviewed on Feb 5, 2026

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

$746

per person

Apr 23 - Apr 28

found 22 hours ago

Roundtrip non-stop flight included

New York (NYC) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,376

per person

Mar 8 - Mar 15

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

Excellent service, large rooms and very clean

Reviewed on Jan 28, 2026

Don't see what you're looking for?

See all available trips from Columbus to La Raya de Santa María

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-05/2026-03-12/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=CTD&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## La Raya de Santa María Hotel Deals

![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Gran David

Vía Interamericana Santiago Veraguas

Fully refundableReserve now, pay when you stay

$71 nightly

$79 total

Feb 15 - Feb 16

Total with taxes and fees

8.4/10 Very Good! (373 reviews)

Great Service! Clean and comfortable rooms. The owner and staff very friendly. I will come back again. Recommend it !

Reviewed on Feb 2, 2026

[](https://expedia.com/Hotel-Search?startDate=2%2F15%2F2026&endDate=2%2F16%2F2026&selected=12003378&PinnedHotelID=12003378&HadPinnedHotel=true&regionId=829297289699811328)

![Hotel Mykonos Panama](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/cdb98b1d_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Mykonos Panama

Panamerican Highway Nuevo Santiago Veraguas

$90 nightly

$99 total

Feb 6 - Feb 7

Total with taxes and fees

8.8/10 Excellent! (544 reviews)

Everything was great!

Reviewed on Dec 17, 2025

[](https://expedia.com/Hotel-Search?startDate=2%2F6%2F2026&endDate=2%2F7%2F2026&selected=5270392&PinnedHotelID=5270392&HadPinnedHotel=true&regionId=829297289699811328)

![HOTEL VISTA LAGO](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/4e3dd11f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

HOTEL VISTA LAGO

Rincón Largo La Pena Santiago de Veraguas

Fully refundableReserve now, pay when you stay

$77 nightly

$84 total

Feb 6 - Feb 7

Total with taxes and fees

9.2/10 Wonderful! (90 reviews)

Great atmosphere around the restaurant and pool. We found it very relaxing in an otherwise busy city. Restaurant makes good meals and the service is great.

Reviewed on Feb 4, 2026

[](https://expedia.com/Hotel-Search?startDate=2%2F6%2F2026&endDate=2%2F7%2F2026&selected=95675257&PinnedHotelID=95675257&HadPinnedHotel=true&regionId=829297289699811328)

[See all 15 properties in La Raya de Santa María](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026&regionId=829297289699811328)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best La Raya de Santa María Vacation Packages

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## Frequently asked questions

### How to find the best La Raya de Santa María package deals?

### When to book a vacation package to La Raya de Santa María?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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