Find hotels near Louisville Science Center, Louisville from $82

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Louisville Science Center hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 mi from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Location and the staff was fabulous."
United States
Madeline
$183 nightly
The price is $216
Feb 17 - Feb 18
Total with taxes and fees
21c Museum Hotel Louisville

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 mi from Louisville Science Center
9.4 out of 10, Exceptional, (1,005 reviews)
"Property was very well taken care of and unique. Staff was friendly and helpful. Room was very nice and the price was great!"
United States
Erica
$195 nightly
The price is $229
Feb 22 - Feb 23
Total with taxes and fees
The Grady

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.6 mi from Louisville Science Center
9.6 out of 10, Exceptional, (444 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
$195 nightly
The price is $229
Mar 8 - Mar 9
Total with taxes and fees
Hotel Distil, Autograph Collection

Market Street Inn

Market Street Inn
3.5 star property
1.3 mi from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
$185 nightly
The price is $209
Feb 16 - Feb 17
Total with taxes and fees
Market Street Inn

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 1.8 mi from Louisville Science Center
10.0 out of 10, Exceptional, (22 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
$265 nightly
The price is $308
Feb 15 - Feb 16
Total with taxes and fees
Louisville Bourbon Inn

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 1.7 mi from Louisville Science Center
9.8 out of 10, Exceptional, (102 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
$141 nightly
The price is $164
Feb 17 - Feb 18
Total with taxes and fees
DuPont Mansion Bed & Breakfast

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 0.8 mi from Louisville Science Center
9.4 out of 10, Exceptional, (1,182 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
$179 nightly
The price is $211
Feb 15 - Feb 16
Total with taxes and fees
The Brown Hotel

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.2 mi from Louisville Science Center
9.2 out of 10, Wonderful, (538 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
$114 nightly
The price is $134
Mar 1 - Mar 2
Total with taxes and fees
Towneplace Suites By Marriott Louisville Downtown

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 0.8 mi from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay "
United States
Sarah
$108 nightly
The price is $127
Feb 28 - Mar 1
Total with taxes and fees
Cambria Hotel Louisville Downtown-Whiskey Row

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 1.4 mi from Louisville Science Center
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
$159 nightly
The price is $185
Mar 11 - Mar 12
Total with taxes and fees
Stellar Suites

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 1.3 mi from Louisville Science Center
9.2 out of 10, Wonderful, (1,036 reviews)
"Spotless room and courteous staff "
United States
Mary
$135 nightly
The price is $159
Feb 17 - Feb 18
Total with taxes and fees
Hotel Genevieve part of JdV by Hyatt

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville, 1.8 mi from Louisville Science Center
9.2 out of 10, Wonderful, (63 reviews)
"My partner and I do regular romantic staycations at Central Park Inn and we love it. The rooms are comfortable and unique and the staff we've met are lovely. "
United States
Amanda
$134 nightly
The price is $156
Feb 15 - Feb 16
Total with taxes and fees
Central Park Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville, 1.4 mi from Louisville Science Center
10.0 out of 10, Exceptional, (4 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
$232 nightly
The price is $269
Feb 18 - Feb 19
Total with taxes and fees
Bourbon Barrel Inn Bed & Breakfast

Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 mi from Louisville Science Center
8.8 out of 10, Excellent, (1,002 reviews)
"Great space to stay while traveling; clean room; breakfast was good."
United States
Marleena
$111 nightly
The price is $131
Feb 26 - Feb 27
Total with taxes and fees
Residence Inn by Marriott Louisville Downtown

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
Downtown Louisville, 0.6 mi from Louisville Science Center
8.4 out of 10, Very Good, (1,007 reviews)
"nice hotel, great staff "
United States
Olivia
$105 nightly
The price is $124
Mar 1 - Mar 2
Total with taxes and fees
Hilton Garden Inn Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.7 mi from Louisville Science Center
8.4 out of 10, Very Good, (1,002 reviews)
"Great location "
United States
Corina
$110 nightly
The price is $129
Feb 15 - Feb 16
Total with taxes and fees
SpringHill Suites by Marriott Louisville Downtown

Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
Downtown Louisville, 0.6 mi from Louisville Science Center
8.4 out of 10, Very Good, (1,003 reviews)
"Good place to stay and a great location."
United States
Joshua
$88 nightly
The price is $103
Feb 17 - Feb 18
Total with taxes and fees
Hampton Inn Louisville Downtown

Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG
3.0 star property
Downtown Louisville, 0.7 mi from Louisville Science Center
8.0 out of 10, Very Good, (786 reviews)
"Overall, a really nice stay"
United States
Melissa
$70 nightly
The price is $82
Feb 16 - Feb 17
Total with taxes and fees
Holiday Inn Louisville Downtown by IHG

Hancock House

Hancock House
3.0 star property
East Market District, 1.1 mi from Louisville Science Center
8.2 out of 10, Very Good, (249 reviews)
"Great stay!"
United States
Tim
$121 nightly
The price is $141
Feb 11 - Feb 12
Total with taxes and fees
Hancock House

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott
3.5 star property
1.1 mi from Louisville Science Center
8.2 out of 10, Very Good, (1,002 reviews)
"Friendly helpful staff, clean rooms, well equipped gym. Easy parking & walkable to restaurants & town. Louisville just over the bridge."
United States
Mary
$93 nightly
The price is $105
Feb 28 - Mar 1
Total with taxes and fees
Sheraton Louisville Riverside by Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Louisville Science Center

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,004 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,005 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
444 reviews
View
Interior entrance
Market Street Inn
3.5 star property
9.8
Exceptional
120 reviews
View
Interior entrance
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
22 reviews
View

Top Louisville Science Center Hotel Reviews

Hotels near other Louisville Science Center attractions

Frequently asked questions

What are the top-rated hotels near Louisville Science Center?
Discover the top-rated hotels near the Louisville Science Center that promise an unforgettable stay filled with comfort and convenience.

Louisville Bourbon Inn

Louisville Bourbon Inn stands out with a perfect review rating of 10 and is a luxurious 5-star hotel located just 2.3 miles from the Louisville Science Center. This exquisite hotel features elegant rooms with premium bedding and Egyptian cotton sheets. Guests can indulge in a private hot tub, enjoy complimentary breakfasts daily, and relax on their furnished balcony. With amenities like in-room massages and couples dining, this hotel is ideal for a romantic getaway.

☼ 2 Bedrooms New / Elegant / Calm in HIP Highlands ► Walkable

This elegant 2-bedroom accommodation is located 3.1 miles from the Louisville Science Center and has earned a stellar review rating of 10, complemented by a 4-star rating. The hotel features a well-equipped kitchen and a spacious deck or patio, allowing travelers to enjoy the outdoors. With amenities like air conditioning and nearby fitness facilities, it provides a perfect blend of comfort and convenience, making it a great choice for those looking to explore the vibrant Highlands area.

First Class Stunner | Highlands Private 1 BR/1BA

First Class Stunner is a charming option just 3.1 miles from the Louisville Science Center, with an impressive review rating of 10. This inviting hotel offers a fully equipped kitchen with modern appliances, including a dishwasher and oven, perfect for those who enjoy cooking. Guests can unwind on the patio or engage in nearby hiking and biking activities. The historic charm of this accommodation, combined with its nearby local shopping and winery tours, makes it a delightful stay.
What hotels are within walking distance to Louisville Science Center?
Discover top-rated hotels just a stroll away from the Louisville Science Center, perfect for your next adventure.

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection is a 4-star hotel that offers an impressive review rating of 9.6, located just an 11-minute walk from the Louisville Science Center. Guests can enjoy a romantic atmosphere with riverside views from the rooftop terrace. The hotel features 24-hour fitness facilities, valet parking, and daily housekeeping to ensure a comfortable stay. Premium bedding and complimentary toiletries enhance the experience, making it a great choice for travelers seeking luxury and convenience.

The Brown Hotel

With a stellar review rating of 9.4, The Brown Hotel is a luxurious 4.5-star hotel located 19 minutes on foot from the Louisville Science Center. This historic hotel offers travelers an art gallery onsite, valet parking, and a boutique shopping experience. Comfort is prioritized with Egyptian cotton sheets and daily housekeeping. The hotel also features a lounge for club-level travelers where continental breakfast is served, perfect for travelers looking for a touch of elegance.

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row is a charming 3-star hotel a review rating of 9.4, situated just 16 minutes walking from the Louisville Science Center. Ideal for travelers looking for comfort, the hotel features an indoor pool, 24-hour fitness facilities, and convenient self-parking. With a focus on family-friendly amenities, travelers can enjoy a complimentary breakfast and an inviting atmosphere.
How much is a hotel near Louisville Science Center?
Staying near Louisville Science Center is a treat, with plenty of hotels from $82 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Louisville Science Center?
Finding the perfect family-friendly hotel near Louisville Science Center is essential for a memorable trip. Here are some top-rated options that cater to families and ensure a delightful stay.

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY is ideally located just 2 minutes from Louisville Science Center. This 3-star hotel boasts a great traveler rating score of 9.2 and caters perfectly to families with accessible pools, complimentary breakfast, and connecting rooms. Guests will also enjoy the convenience of a kitchenette equipped with a microwave and dishwasher, ensuring a comfortable and straightforward stay.

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown is just a 5-minute walk from Louisville Science Center, making it a convenient choice for families. Rated 9.2 by travelers, this 3-star hotel offers a host of family-friendly amenities including an indoor pool, free buffet breakfast, and toys for children. Guests will appreciate the fully equipped kitchens, featuring a microwave and dishwasher, which make meal prep easy during their stay.

Four Points by Sheraton Louisville Airport

Four Points by Sheraton Louisville Airport, located 4.5 miles from Louisville Science Center, is a family-friendly option with a review rating of 8.6. This 3-star hotel features amenities such as an accessible pool and kids' meals at the on-site restaurant. Families will appreciate the spacious suites equipped with separate living areas and rollaway beds available at no extra charge, perfect for a relaxing getaway.
Are there any 5-star hotels near Louisville Science Center?
Discover the top-rated 5-star hotels near the Louisville Science Center, where comfort meets elegance for an unforgettable stay.

Louisville Bourbon Inn

Louisville Bourbon Inn is a luxurious 5-star retreat located just 2.3 miles from the Louisville Science Center. With an outstanding review rating of 10, this hotel offers travelers an exquisite experience complete with private hot tubs and beautifully furnished balconies. Guests can savor a complimentary full breakfast each morning and enjoy the romantic ambiance enhanced by designer toiletries and premium bedding. With additional amenities like in-room massage services and the option for winery tours nearby, this hotel ensures a memorable stay for all travelers.
Which hotels near Louisville Science Center offer the best views?
Discover the perfect stay near Louisville Science Center with stunning views and top-rated amenities.

Hotel Distil, Autograph Collection

Hotel Distil is a luxurious 4-star hotel with an impressive 9.6 review rating, situated just an 11-minute walk from Louisville Science Center. Guests are treated to stunning river views and a rooftop terrace that provides a unique vantage point of the city. The hotel includes a 24-hour fitness center and a gourmet restaurant, perfect for those wanting to indulge after a day of sightseeing. With its romantic atmosphere and exceptional service, this hotel is ideal for travelers looking for a memorable stay.

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside, rated 8.2 by travelers, is a cozy 3.5-star hotel located 1.9 miles from Louisville Science Center. Guests can enjoy beautiful river views and access to a 24-hour fitness center. The hotel features an indoor pool and complimentary parking, making it convenient for those exploring the area. With its inviting atmosphere and friendly concierge service, it's a great choice for travelers seeking both comfort and scenic sights.

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel, a 4-star hotel, is just a 7-minute walk from Louisville Science Center and boasts a remarkable review rating of 8.8. This hotel offers breathtaking river views from its rooms, enhancing the overall experience for travelers. Amenities include a full-service spa, an outdoor pool, and a fitness center, as well as onsite shopping. Travelers can also indulge in a variety of spa treatments, making it a relaxing retreat after a day of exploration.
What are the best affordable hotels near Louisville Science Center?
For those looking for affordable stays that are both top-rated and family-friendly near Louisville Science Center, these options offer great comfort and convenience.

Heart of Kentucky Home! Ideal Location

Just 2.7 miles from Louisville Science Center, Heart of Kentucky Home boasts a perfect review rating of 10 and is rated 3 stars. This charming home is perfect for family gatherings and events, providing a warm atmosphere for travelers. Its prime location makes it easy to explore the nearby attractions while enjoying a comfortable stay.

First Class Stunner | Highlands Private 1 BR/1BA

Located 3.1 miles from Louisville Science Center, First Class Stunner offers a perfect retreat with a review rating of 10. This cozy one-bedroom features a kitchen with a refrigerator and oven, ideal for families wishing to prepare meals together. Guests can relax on the patio or enjoy the garden area, making it a lovely spot for unwinding after a day of exploration.

Sleep in a Restored 175-Year-Old Church

Sleep in a Restored 175-Year-Old Church is a unique stay located only 1.4 miles from Louisville Science Center. With a review rating of 9.8, this historical hotel combines charm with comfort. Families will appreciate the fully-equipped kitchen and kid-friendly amenities, including toys and games. The beautiful patio offers a serene space for relaxation after a busy day.
What are the best boutique hotels near Louisville Science Center?
For a delightful stay near Louisville Science Center, these top-rated boutique hotels offer charm and comfort, perfect for families or couples alike.

Market Street Inn

Market Street Inn is a charming 3.5-star boutique hotel located just 2.1 miles from Louisville Science Center. Rated 9.8 by travelers, this cozy retreat features romantic settings and offers complimentary breakfast to start your day. Guests appreciate the rooftop terrace, perfect for enjoying the view, and the cozy fireplace that adds warmth to your stay.

The Brown Hotel

The Brown Hotel is a historic 4.5-star boutique hotel situated within a scenic 19-minute walk from Louisville Science Center, a review rating of 9.4. Visitors can indulge in the convenience of valet parking and enjoy the premium bedding for a restful night.

21c Museum Hotel Louisville

21c Museum Hotel Louisville stands out with its unique artistic flair, situated a mere minute's walk from Louisville Science Center. With a travelers' rating of 9.2 and a 4.5-star designation, this boutique hotel features a full-service spa and 24-hour fitness facilities. Guests can unwind in luxurious rooms complete with designer toiletries and enjoy complimentary access to yoga classes, ensuring a rejuvenating experience.
Are there any hotels with pools close to Louisville Science Center?
If you're looking for hotels with pools near the Louisville Science Center, here are some excellent options that cater to your comfort and relaxation needs.

Homewood Suites By Hilton Louisville Airport

Homewood Suites By Hilton Louisville Airport is a cozy 3-star hotel situated 4.8 miles from the Louisville Science Center, with an impressive review rating of 9.4. The hotel features an accessible outdoor pool with sun loungers, perfect for family-friendly relaxation. Guests can also enjoy complimentary breakfast, fitness facilities, and convenient kitchen amenities for a home-like stay.

Omni Louisville Hotel

Omni Louisville Hotel, rated 9.2 by travelers, is a luxurious 4-star hotel located just a short 13-minute walk from the Louisville Science Center. The outdoor pool features sun loungers, cabanas, and a poolside bar, making it an ideal spot to relax. Guests can also indulge in spa services, enjoy fine dining, and take advantage of fitness facilities, providing a well-rounded experience.

The Myriad Hotel Louisville, Tapestry Collection by Hilton

The Range Hotel Louisville is a delightful 3.5-star hotel located just 2.6 miles from the Louisville Science Center, featuring a great traveler rating score of 9.0. Guests can enjoy an outdoor pool complete with sun loungers, cabanas, and a poolside bar, perfect for unwinding after a day of exploration. Additional amenities include a restaurant, fitness facilities, and premium bedding, ensuring a comfortable stay.
What are the best pet-friendly hotels near Louisville Science Center?
If you're looking for pet-friendly hotels near Louisville Science Center, you're in for a treat with these top-rated options that cater to both your and your furry friend's needs.

Candlewood Suites Louisville - NE Downtown Area by IHG

Candlewood Suites Louisville - NE Downtown Area by IHG offers a welcoming place for travelers and their pets, just 4.3 miles from Louisville Science Center. With a solid review rating of 9.0, travelers can enjoy amenities such as a dog exercise area and pet-friendly rooms. Additional features include a fitness center, accessible parking, and free self-parking, ensuring a comfortable stay for all.

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown is a fantastic choice just a short 5-minute walk from Louisville Science Center. Rated 9.2 by travelers, this 3-star hotel provides an array of pet-friendly amenities including food and water bowls for your furry companions. Guests can also enjoy complimentary breakfast, an indoor pool, and convenient onsite parking, making it an ideal spot for families and pet owners alike.

Moxy Louisville Downtown

Moxy Louisville Downtown is a vibrant hotel located just 12 minutes from Louisville Science Center, a review rating of 9.0. This 3.5-star hotel welcomes both dogs and cats, providing pet-friendly accommodations and essential amenities like food and water bowls. Guests can unwind on the terrace, take advantage of 24-hour fitness facilities, and enjoy daily housekeeping, ensuring a refreshing and inviting stay.
Can I book a fully refundable hotel close to Louisville Science Center?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Louisville Science Center", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.
Can I find Expedia discounts for hotels near Louisville Science Center?
To look for discounts on hotels near Louisville Science Center, join One Key™—our free travel rewards program. One Key members always get our best prices and earn OneKeyCash™* on eligible bookings for every dollar spent. Another way to save is by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Explore a world of travel with Expedia