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Compare 1,809 hotels close to Louisville Science Center with room rates, reviews, and availability. Most hotels are fully refundable.

The Grady

4.0 star property
9.4 out of 10, Exceptional, (997)
"Lovely hotel at a great location. "
$160 nightly
The price is $188
Jul 27 - Jul 28
Total includes taxes and fees
The Grady

Hotel Distil, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (390)
"Great bar"
$159 nightly
The price is $187
Aug 10 - Aug 11
Total includes taxes and fees
Hotel Distil, Autograph Collection

Homewood Suites by Hilton Louisville Downtown, KY

3.0 star property
9.2 out of 10, Wonderful, (1003)
"Good hotel "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Homewood Suites by Hilton Louisville Downtown, KY

Market Street Inn

3.5 star property
9.8 out of 10, Exceptional, (112)
"Beautiful historic building that has been done up to luxury status. Very thoughtful things like bottled water and popcorn are available."
$167 nightly
The price is $188
Jul 20 - Jul 21
Total includes taxes and fees
Market Street Inn

Louisville Bourbon Inn

5.0 star property
10.0 out of 10, Exceptional, (16)
"Wonderful experience with Victorian era Decor and fabulous Southern Breakfast. "
$265 nightly
The price is $308
Jul 14 - Jul 15
Total includes taxes and fees
Louisville Bourbon Inn

The Brown Hotel

4.5 star property
9.4 out of 10, Exceptional, (1023)
"Great stay "
$179 nightly
The price is $211
Jul 20 - Jul 21
Total includes taxes and fees
The Brown Hotel

21c Museum Hotel Louisville

4.5 star property
9.2 out of 10, Wonderful, (1004)
"Excellent place to stay. "
$155 nightly
The price is $183
Aug 11 - Aug 12
Total includes taxes and fees
21c Museum Hotel Louisville

Cambria Hotel Louisville Downtown-Whiskey Row

3.0 star property
9.4 out of 10, Exceptional, (1014)
"Great room and staff The hotel is excellent and will stay there in the future"
$118 nightly
The price is $139
Jul 27 - Jul 28
Total includes taxes and fees
Cambria Hotel Louisville Downtown-Whiskey Row

DuPont Mansion Bed & Breakfast

3.0 star property
9.8 out of 10, Exceptional, (76)
"The property was beautiful and so peaceful "
$141 nightly
The price is $164
Jul 22 - Jul 23
Total includes taxes and fees
DuPont Mansion Bed & Breakfast

Omni Louisville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1503)
"Fantastic stay."
$159 nightly
The price is $187
Aug 8 - Aug 9
Total includes taxes and fees
Omni Louisville Hotel

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
9.4 out of 10, Exceptional, (643)
"wonderful stay"
$127 nightly
The price is $149
Jul 17 - Jul 18
Total includes taxes and fees
Tempo By Hilton Louisville Downtown Nulu

Stellar Suites

4.5 star property
9.6 out of 10, Exceptional, (99)
"Great spot a must stay"
$165 nightly
The price is $192
Jul 28 - Jul 29
Total includes taxes and fees
Stellar Suites

Towneplace Suites By Marriott Louisville Downtown

3.0 star property
9.0 out of 10, Wonderful, (414)
"Very clean and excellent location - friendly staff "
$97 nightly
The price is $114
Aug 3 - Aug 4
Total includes taxes and fees
Towneplace Suites By Marriott Louisville Downtown

Holiday Inn Express & Suites Louisville Downtown by IHG

2.5 star property
8.8 out of 10, Excellent, (1491)
"Great staff, nice and clean hotel. "
$83 nightly
The price is $98
Aug 4 - Aug 5
Total includes taxes and fees
Holiday Inn Express & Suites Louisville Downtown by IHG

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
8.8 out of 10, Excellent, (3447)
"Great stay"
$141 nightly
The price is $166
Aug 10 - Aug 11
Total includes taxes and fees
Galt House Hotel Trademark Collection by Wyndham

Aloft Louisville Downtown

3.0 star property
9.0 out of 10, Wonderful, (1007)
"Great location on Whiskey Row with friendly staff! Beds are comfortable and restaurant onsite. "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Aloft Louisville Downtown

Hotel Genevieve part of JdV by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (894)
"Great stay! "
$135 nightly
The price is $159
Jul 20 - Jul 21
Total includes taxes and fees
Hotel Genevieve part of JdV by Hyatt

Louisville Marriott Downtown

4.0 star property
9.0 out of 10, Wonderful, (1001)
"Beautiful hotel and excellent service. Location is great too. Will stay at the Marriott when back in Louisville "
$159 nightly
The price is $187
Aug 1 - Aug 2
Total includes taxes and fees
Louisville Marriott Downtown

Moxy Louisville Downtown

3.5 star property
9.0 out of 10, Wonderful, (632)
"Cool property, good restaurant and solid location! "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Moxy Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
8.8 out of 10, Excellent, (1009)
"Great hotel"
$118 nightly
The price is $139
Aug 3 - Aug 4
Total includes taxes and fees
Embassy Suites Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 247 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 247 hotels and other accommodations within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.