Matthews Vacation Rentals

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In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

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Top Matthews Hotel Reviews

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston

10/10 Excellent

Staff was really nice
United States
Stacey
Reviewed April 10, 2025
Hampton Inn Sikeston

Find out more about Matthews

Everything you need to know about Matthews vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Matthews vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Matthews vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Matthews vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Matthews. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Matthews in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $154 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Matthews rentals

At Expedia, we put the best Matthews vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Matthews rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Matthews vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Matthews. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Are there vacation rentals in Matthews?

Yes, we offer vacation rentals near the most popular local attractions in Matthews, or you can choose a secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Matthews has to offer?

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This vacation home rental near Matthews offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games.

What’s there to see and do in Matthews?

While you're exploring the area, Big Oak Tree State Park and Central Park are a couple of picturesque spots to get outside and enjoy nature. Marston Community Center and Sikeston Depot Museum are a couple of places you'll find in the larger area.

What’s a vacation rental in Matthews like?

Vacation rentals are privately owned properties you can book for a few weeks or just a few days in Matthews. Vacation rentals feature amenities such as laundry facilities and kitchens so you'll have all the conveniences of home. If you're concerned about a clean environment, vacation rentals can offer a sense of security away from shared hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.