Matthews Vacations from $355

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The Latest Matthews vacation packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
8.8/10 Excellent! (576 reviews)
Our first room was stained, dirty, and not acceptable. I asked for another room and was given a room that looked like it was in another hotel altogether. It was clean, big, comfortable. Perfect. The staff was super friendly and helpful.

Reviewed on Jul 4, 2025

Makanda Inn

Makanda Inn

3.5 out of 5
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
10/10 Exceptional! (32 reviews)
Peaceful and relaxing.

Reviewed on May 20, 2025

Rockwood Inn

Rockwood Inn

2 out of 5
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
10/10 Exceptional! (12 reviews)
The property seemed to run on its own. We never saw the staff, except for one brief meeting of the owner. The Inn is beautiful and well maintained. We were quite comfortable.

Reviewed on May 28, 2025

The Riverview

The Riverview

2 out of 5
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.4/10 Exceptional! (306 reviews)
Wonderful place to stay. Very clean and affordable!

Reviewed on Jul 6, 2025

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
per person
Sep 11 - Sep 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.6/10 Exceptional! (73 reviews)
Great, clean room and the restaurant attached was delicious- best breakfast!

Reviewed on Jun 29, 2025

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Matthews Hotel Deals

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Jul 13 to Jul 14
$101 total
Jul 13 - Jul 14
Total includes taxes and fees
8.2/10 Very Good! (1,005 reviews)
"Didn’t have to think about anything. It was all right."

Reviewed on Jul 3, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $117 total per night from Jul 11 to Jul 12
$117 total
Jul 11 - Jul 12
Total includes taxes and fees
9.4/10 Exceptional! (1,003 reviews)
Nice place to stop.
"Nice, clean hotel. It’s a very small town, but there is fast food nearby and close to the interstate. We made a quick one night stop but enjoyed the indoor/outdoor pool and indoor hot tub. The parking lot was very wel lit and the area felt safe."

Reviewed on Jun 30, 2025

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Jul 13 to Jul 14
$103 total
Jul 13 - Jul 14
Total includes taxes and fees
9.2/10 Wonderful! (1,001 reviews)
"Very clean room and pool and good breakfast!"

Reviewed on Jun 30, 2025

Pear Tree Inn Sikeston
See all 35 properties in Matthews
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Matthews Vacation Packages

Matthews Essential Information

Language
English
Currency
U.S dollars
Population
630

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Frequently asked questions

How much does a Matthews vacation package cost?
You'll find cheap prices from $355 on Expedia for your Matthews escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Matthews costs.
What are the cheapest months to go to Matthews?
If you're hoping to score a cheap Matthews vacation package, consider traveling in January, September and November. You're likely to find better prices on flights and accommodations during these months --- perfect for travelers wishing to save money.
How many days is enough for Matthews?
Usually, a handful of days is enough to visit the major attractions during your Matthews vacation. But if you want to have time to chill out or take day tours, think about extending your trip.
How to find the best Matthews package deals?
Begin your search for a Matthews package deal by entering your travel dates and destination under our "Packages" tab. Then apply some filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Matthews package deal right away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Matthews escape off to a flying start.
Is it cheaper to book a Matthews vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging accommodations and flights separately. Better still, you can customize your Matthews trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Matthews?
If you've got your Matthews travel dates locked in, book as early as you can to bag some unbeatable deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for traveling on a whim.
Does Expedia offer Book Now, Pay Later Matthews vacation packages?
Your Matthews getaway should be a relaxing escape from your busy life, not a reason for money worries. So to allow you that extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.