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Expedia's extensive Lithuania database doesn't list any places to stay in the vicinity of Mazeikiai.
Liepaja is 50 miles to the west of Mazeikiai, and is home to the House of Peter and Northern Fort. If you'd like to spend a night or two in Liepaja, be sure to check out the Promenade Hotel and Liva Hotel. 55 miles to the southwest of Mazeikiai is Palanga, home to the Palanga SPA Luxury Hotel and Palangos Vetra. Palanga Beach and Palanga Pier are popular attractions to experience for those visiting Palanga.
60 miles from Mazeikiai is Klaipeda, a regional center with a population of 190,000, home to great places to see like the Martynas Mazvydas Sculpture Park, Lithuanian Sea Museum and the New Ferry Terminal. The History Museum of Lithuania Minor and Clock and Watch Museum are also worth checking out. The Friedricho Pasazas and Ararat All Suites Hotel are all great Expedia-listed places to stay in Klaipeda.