Title: Top 10 Hotels in Mesopotamia from $65 - Competitive Prices | Expedia.com [Mesopotamia Travel Guide](https://expedia.com/Mesopotamia.dx6335336)[Vacation Rentals in Mesopotamia](https://expedia.com/Mesopotamia-Vacation-Rentals.d6335336.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.com/Cheap-Flights-To-Mesopotamia.d6335336.Travel-Guide-Flights)[Car Rentals in Mesopotamia](https://expedia.com/Car-Rentals-In-Mesopotamia.d6335336.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.com/Mesopotamia.d6335336.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 8 - Feb 9](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-02-08&endDate=2026-02-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia hotels ![Interior](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/68e1bf42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/293745cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/d97c5d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room Green | In-room safe, blackout drapes, soundproofing, free WiFi](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/a1a2c760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### To Spiti tis Sofias [](https://www.expedia.com/Kastoria-Hotels-To-Spiti-Tis-Sofias.h100775775.Hotel-Information) Kastoria 10/10 Exceptional (1 review) "Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. " ![France](https://a.travel-assets.com/egds/marks/flags/fr.svg) Anonymous traveler $67 nightly $77 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-To-Spiti-Tis-Sofias.h100775775.Hotel-Information) ![Lunch and dinner served](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/bf296f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/d1622ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/5492b092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/9efd4fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guesthouse Monopati [](https://www.expedia.com/Amyntaio-Hotels-Guesthouse-Monopati.h74421141.Hotel-Information) Amyntaio 10/10 Exceptional (3 reviews) [](https://www.expedia.com/Amyntaio-Hotels-Guesthouse-Monopati.h74421141.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/8b1d5aa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/1725b636.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/69491c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/eb506c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Limneon Resort & Spa [](https://www.expedia.com/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) Kastoria 9.2/10 Wonderful (198 reviews) "Wonderful stay. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Konstantinos $105 nightly $123 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/f9d4f59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/9ba53a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/e9d6e7a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Anastassiou [](https://www.expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) Kastoria 8.0/10 Very Good (69 reviews) "Nice simple stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey [](https://www.expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/154a1dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/6e5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/e21f5828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/b7911c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Ilektra [](https://www.expedia.com/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information) Voio 9.8/10 Exceptional (11 reviews) "Friendly and courteous hosts, great food and excellent service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pantelia $62 nightly $71 total Feb 10 - Feb 11 Total with taxes and fees [](https://www.expedia.com/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/4efcf6fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/61d57c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/327f7f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Lake View | Individually decorated, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/1df39c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guesthouse Vissinokipos [](https://www.expedia.com/Kastoria-Hotels-Guesthouse-Vissinokipos.h18331611.Hotel-Information) Kastoria 9.4/10 Exceptional (10 reviews) "Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmen [](https://www.expedia.com/Kastoria-Hotels-Guesthouse-Vissinokipos.h18331611.Hotel-Information) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/24141309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/6e4b8b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/90243f5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/3ebef3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kyknos De Luxe Hotel [](https://www.expedia.com/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) Kastoria 10/10 Exceptional (43 reviews) "Very nice clean, very polite staff and great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vasilios $91 nightly $105 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/w6487h5400x7y9-009caa8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/94e01b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/18af8a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/5972a4f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Calma Hotel & Spa [](https://www.expedia.com/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) Kastoria 9.6/10 Exceptional (35 reviews) "Pleasant stay. Good amenities. Great staff. " ![New Zealand](https://a.travel-assets.com/egds/marks/flags/nz.svg) Robert [](https://www.expedia.com/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/aba1ef30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/7b4f5682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/2841eed6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/e63d45bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orologopoulos Mansion [](https://www.expedia.com/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information) Kastoria 9.6/10 Exceptional (36 reviews) "Ideal accommodation in a tranquil area of the town, surrounded by character buildings. Several quality eating locations near by." ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mark $103 nightly $122 total Feb 18 - Feb 19 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/bf0edcd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/7b18d73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/29cb6748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/82f1b7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Esperos Palace Luxury & Spa Hotel [](https://www.expedia.com/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) Kastoria 9.0/10 Wonderful (84 reviews) "The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michal [](https://www.expedia.com/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/5a9847cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Lake View | Living area | LED TV](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/da0670f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/37147189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/61858d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chloe Hotel [](https://www.expedia.com/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) Kastoria 10/10 Exceptional (87 reviews) "We enjoyed the stay, friendly staff and nice breakfast " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Fani $102 nightly $118 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/1a61bc01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/cb9be105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/17494fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/777f6cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anesis Hotel [](https://www.expedia.com/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) Kastoria 9.0/10 Wonderful (9 reviews) "Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Adam $56 nightly $65 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/2c3bb5a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/45db7f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/6496fadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/b1efecbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Andromeda Boutique hotel [](https://www.expedia.com/Kastoria-Hotels-Andromeda-Boutique-Hotel.h88283893.Hotel-Information) Kastoria 8.8/10 Excellent (3 reviews) [](https://www.expedia.com/Kastoria-Hotels-Andromeda-Boutique-Hotel.h88283893.Hotel-Information) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/da27481d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/a411bbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/c74e29e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/43f9dc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sunset Haven Kastoria Modern Lake Elegance [](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information) Kastoria [](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=6335336&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6335336.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6335336.Travel-Guide-Hotels) ## Top Mesopotamia Hotel Reviews ![Limneon Resort & Spa](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/009cc717_y.jpg) ### Limneon Resort & Spa 10/10 Excellent "This is an incredible hotel for families - child friendly, clean, and wonderful facilities. There is a small indoor play zone with someone who looks after the kids. The breakfast buffet is fantastic. The indoor pool is lovely. Everyone that works here is the kindest! My family and I had a wonderful stay " [](https://expedia.com/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) ![Guest House Ilektra](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/154a1dd3_y.jpg) ### Guest House Ilektra 10/10 Excellent "Friendly and courteous hosts, great food and excellent service " [](https://expedia.com/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information) ![Kyknos De Luxe Hotel](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/9ba540ac_y.jpg) ### Kyknos De Luxe Hotel 10/10 Excellent "The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods" [](https://expedia.com/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) ![Orologopoulos Mansion](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/a88b51c3_y.jpg) ### Orologopoulos Mansion 10/10 Excellent "Wonderful stay Very well kept hotel Nice room with a warm feeling The spaces in hotel are beautiful and give you the feeling that you stay at a luxurious home Very good breakfast- I will definitely stay here again " [](https://expedia.com/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information) ![Esperos Palace Luxury & Spa Hotel](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/42ff45d8_y.jpg) ### Esperos Palace Luxury & Spa Hotel 10/10 Excellent "The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. " [](https://expedia.com/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) ![The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη](https://images.trvl-media.com/lodging/35000000/34940000/34934000/34933999/7e2a3abb_y.jpg) ### The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη 10/10 Excellent "Γουστόζικο, περιποιημένο, πεντακάθαρο σπίτι σε τέλεια τοποθεσία. Ησυχία με εύκολη πρόσβαση στην πόλη της Καστοριάς και άλλα αξιοθέατα." [](https://expedia.com/Kastoria-Hotels-.h34933999.Hotel-Information) ![Calma Hotel & Spa](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/w6487h5400x7y9-009caa8e_y.jpg) ### Calma Hotel & Spa 10/10 Excellent "Pleasant stay. Good amenities. Great staff. " [](https://expedia.com/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) ![Chloe Hotel](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/37147189_y.jpg) ### Chloe Hotel 10/10 Excellent "Romantic and special. Highly recommend. Kastoria is a rare find. This hotel is a great getaway. " [](https://expedia.com/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) ![Hotel Anastassiou](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775_y.jpg) ### Hotel Anastassiou 8/10 Good "Nice simple stay." [](https://expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) ## More cheap stays in Mesopotamia ![Anesis Hotel](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/1a61bc01_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Anesis Hotel Grammou 10 Kastoria $56 nightly $65 total Feb 9 - Feb 10 Total with taxes and fees [](https://expedia.com/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) ![Hotel Anastassiou](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Anastassiou 1st km Highway Kastoria-Athens Kastoria Western Macedonia [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&selected=6136437&PinnedHotelID=6136437&HadPinnedHotel=true®ionId=6335336) 7.8/10 Good! (69 reviews) [](https://expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) ![Arhontiko Christodoulou](https://images.trvl-media.com/lodging/37000000/36790000/36784300/36784216/99031f32_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arhontiko Christodoulou vrontero Prespes [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&selected=36784216&PinnedHotelID=36784216&HadPinnedHotel=true®ionId=6335336) [](https://expedia.com/Prespes-Hotels-Arhontiko-Christodoulou.h36784216.Hotel-Information) ## Hotels in Mesopotamia with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 1 properties [](https://expedia.com/5Star-Mesopotamia-Hotels.s50-0-d6335336.Travel-Guide-Filter-Hotels) ## Find out more about Mesopotamia ### Top reasons to visit Mesopotamia - **Outdoor Adventures:** Mesopotamia offers stunning landscapes and opportunities for hiking and exploring nature. - **Rich Cultural Experiences:** Discover fascinating history museums and local traditions that showcase the village's heritage. - **Romantic Settings:** Enjoy picturesque views and cozy spots perfect for couples looking to unwind. - **Family-Friendly Atmosphere:** The welcoming community and diverse activities make it ideal for travelers of all ages. - **Relaxing Accommodations:** Stay in inviting hotels with spa-themed experiences for a rejuvenating getaway. ### Find great hotels near Mesopotamia Discover a range of inviting hotels in Mesopotamia, Western Macedonia, perfect for business travelers and adventure seekers alike. With a focus on spa-themed experiences, these accommodations offer a blend of comfort and modern amenities. Whether you're searching for the best hotels or competitive room rates, you'll find options that cater to your every need, ensuring a memorable stay in this charming region of Greece. - **[Esperos Palace Luxury & Spa Hotel: ](https://www.expedia.com/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information)** Nestled 5 miles from Mesopotamia, the Esperos Palace Luxury & Spa Hotel is a 4-star oasis ideal for business travelers seeking a touch of relaxation. This property boasts a sophisticated business environment with amenities like a Conference Center and multiple Meeting Rooms. Guests can unwind in the full-service spa, which offers soothing massages, a steam room, and a traditional Turkish bath, alongside an indoor pool. Luxurious and serene, this hotel perfectly blends work and leisure, making it a top choice for those looking to rejuvenate after a busy day. - **[Hotel Anastassiou: ](https://www.expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information)** Located 5 miles away from Mesopotamia, Hotel Anastassiou is the perfect getaway for adventure and business enthusiasts alike. With immediate access to ski lifts and shuttles, guests can easily enjoy exhilarating activities such as skiing, snowboarding, and kayaking nearby. The hotel caters to business needs with a dedicated Business Center and Meeting Rooms. Whether you’re carving down snowy slopes or conducting meetings, this hotel offers a unique blend of excitement and efficiency, ensuring an unforgettable stay for every traveler. - **[Kyknos De Luxe Hotel: ](https://www.expedia.com/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information)** A stylish 3.5-star accommodation situated 5 miles from Mesopotamia, the Kyknos De Luxe Hotel caters to travelers seeking luxury and a business-friendly atmosphere. With well-appointed rooms and essential business amenities, including meeting facilities, this hotel ensures comfort and convenience. Its upscale design and inviting ambiance make it an appealing choice for those looking to combine a high-quality stay with the necessities of a productive trip. Guests can expect attentive service and a relaxing environment, perfect for unwinding after a busy day. ### Where to stay in Mesopotamia Mesopotamia, a charming village in Western Macedonia, Greece, offers a delightful blend of outdoor adventures, romantic getaways, and rich cultural experiences. Nearby cities and neighborhoods provide a family-friendly atmosphere with options for every budget. Enjoy stunning city views and explore the scenic area around Mesopotamia, where friendly locals and trendy spots await. Whether you're seeking relaxation or excitement, this region has something special for every traveler. - **[Kastoria: ](https://www.expedia.com/Kastoria-Hotels.d1928.Travel-Guide-Hotels)** Nestled in the heart of Western Macedonia, Kastoria is a picturesque city surrounded by stunning landscapes and the serene Lake Orestiada. Known for its outdoor adventures and scenic beauty, visitors flock here to enjoy activities like skiing in the nearby mountains and relaxing in local spas. The city boasts a rich history, with captivating historic sites and monasteries that reflect its cultural heritage. A stroll through its charming streets offers a glimpse into traditional life, while the breathtaking views of the lake and mountains provide a perfect backdrop for memorable photographs. - **[Árgos Orestikón: ](https://www.expedia.com/Argos-Orestikon-Hotels.d3000031412.Travel-Guide-Hotels)** Just a short drive from Mesopotamia, Árgos Orestikón is a vibrant city rich in cultural experiences. With a focus on history and heritage, visitors can explore fascinating museums and archaeological sites that showcase the region's storied past. The city is a cultural hub where travelers can immerse themselves in local traditions and craftsmanship. The inviting atmosphere, paired with seasonal festivities peaking in the fall and winter, makes Árgos Orestikón a delightful stop on your journey. - **[Dispilio: ](https://www.expedia.com/Dispilio-Hotels.d6335332.Travel-Guide-Hotels)** Located near the shores of Lake Orestiada, Dispilio is a charming village perfect for those seeking adventure and outdoor sports. The area is popular for skiing, with easy access to ski resorts and fields, making it a winter wonderland for snow enthusiasts. In addition to its thrilling activities, Dispilio offers beautiful lakeside views and cultural experiences, including local museums that delve into the region’s heritage. With its moderate tourist season peaking in the summer, this village is an ideal retreat for nature lovers and adventure seekers alike. ### Things to do in Mesopotamia Mesopotamia, nestled in the picturesque region of Kastoria, offers a delightful mix of outdoor adventures, romantic settings, and rich cultural experiences. Visitors can enjoy visits to local attractions, indulge in the beautiful scenery, and embark on available trips that highlight the area's charm. While there may not be an amusement park directly in Mesopotamia, the surrounding natural beauty and cultural activities provide plenty of entertainment for a memorable vacation. **Shopping** In Mesopotamia, visit local shops for unique souvenirs and gifts. If you're up for a drive, check out the nearby Kozani Mall, offering a range of retail options, from fashion to home goods. Enjoy the vibrant atmosphere and local craftsmanship in the area. **Recreation** Experience the tranquility of the Mesopotamia Wellness Center, where you can indulge in rejuvenating spa treatments and yoga sessions amidst serene natural surroundings. Afterward, explore the beautiful nearby hiking trails, offering stunning views of the landscape, perfect for relaxation and reflection. **Adventure** In Mesopotamia, explore the beautiful Lake Orestiada for kayaking and fishing adventures. Nearby, the stunning Vitsi Mountain offers hiking trails with breathtaking views, perfect for outdoor enthusiasts. Engage with local culture through traditional cuisine and festivals that showcase the rich heritage of Western Macedonia. **Nightlife** The nightlife in Mesopotamia is vibrant and welcoming. Enjoy a lively evening at the local tavern, where you can savor traditional Greek meze while sipping ouzo. For a more energetic vibe, check out the nearby bar featuring live music that keeps the atmosphere buzzing until late. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Mesopotamia To save money on your trip to Mesopotamia, consider visiting in March or October to November when prices are lower. Book your hotel about a month in advance or check for last-minute deals on Expedia, especially on Saturdays for the best rates. Utilize Expedia's search tool to find budget-friendly accommodations by filtering prices from lowest to highest. Take advantage of package deals by combining hotels with flights and activities for extra savings. Joining Expedia's One Key membership can provide exclusive discounts and help you earn rewards for future stays. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Mesopotamia are March and October to November, where the prices are slightly lower. This is in comparison to April and July to August, where prices are slightly higher. - **The best time to book a hotel:** The cheapest time to book a hotel in Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Mesopotamia is Saturday. The most expensive day to stay in Mesopotamia is Thursday. - **Find cheap hotels on Expedia:** Try utilizing Expedia's search tool to refine your choices based on your budget, desired location, and the type of hotel you're looking for. To find the best prices and deals available, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package. - **Become a One Key member:** Join [Expedia's One Key membership](https://www.expedia.com/welcome-one-key) program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels. ### Find the best attractions near Mesopotamia Mesopotamia in Kastoria, Western Macedonia, Greece, is perfect for outdoor, romantic, and culture-themed vacations. Visitors can explore beautiful lakes, fascinating history museums, and notable landmarks. The area's points of interest offer a blend of cultural experiences, scenic views, and opportunities to enjoy the beach, making it an ideal destination for travelers seeking a rich and diverse getaway. - **[Kastoria Lake: ](https://www.expedia.com/Kastoria-Lake-Hotels.0-l553248621532501791-0.Travel-Guide-Filter-Hotels)** Nestled 5 miles from Mesopotamia, Kastoria Lake is a serene escape with picturesque scenery, perfect for romantic walks or outdoor activities. Enjoy the tranquil vibe while taking in the stunning natural beauty. - **[Taxiarhia of the Metropolis: ](https://www.expedia.com/Taxiarhia-Of-The-Metropolis-Hotels.0-l553248621533101283-0.Travel-Guide-Filter-Hotels)** Located 5 miles away, this landmark offers a blend of trendy and luxurious experiences while remaining budget-friendly. It's an ideal spot to appreciate local culture and architecture. - **[Byzantine Museum of Kastoria: ](https://www.expedia.com/Byzantine-Museum-Of-Kastoria-Hotels.0-l6263517-0.Travel-Guide-Filter-Hotels)** Just 6 miles from Mesopotamia, this museum immerses you in the rich history and culture of the Byzantine era, showcasing remarkable artifacts that tell a story of the past. ### Best time to go to Mesopotamia The best time to visit Mesopotamia can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Mesopotamia falls in August, when visitor numbers are moderately high and weather is sunny with no rain. The coolest average temperature in Mesopotamia falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 32.5°F (0.3°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | February | 36.1°F (2.3°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | March | 41.7°F (5.4°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | April | 50.2°F (10.1°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 57.9°F (14.4°C) | Light Rain | Mostly Sunny | Average | Average | | June | 66.0°F (18.9°C) | No Rain | Mostly Sunny | Average | Average | | July | 72.3°F (22.4°C) | No Rain | Sunny | Moderately High | Slightly High | | August | 72.5°F (22.5°C) | No Rain | Sunny | Moderately High | Slightly High | | September | 64.2°F (17.9°C) | No Rain | Mostly Sunny | Moderately High | Average | | October | 54.1°F (12.3°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | November | 45.1°F (7.3°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | | December | 36.3°F (2.4°C) | Light Rain | Mostly Sunny | Average | Average | ### The nearest major airports for your trip to Mesopotamia Traveling to Mesopotamia, Greece, can be conveniently done via two major airports. Kozani Airport ([KZI](https://www.expedia.com/Filippos-Airport-Hotels.0-aKZI-0.Travel-Guide-Filter-Hotels)\-Filippos) is located 38 miles away, with nearby hotel options including [Elimeia 3](https://www.expedia.com/Kozani-Hotels-Elimeia-3.h21152987.Hotel-Information), a 3-star hotel 9 miles from the airport, and [Anesis Hotel](https://www.expedia.com/Kozani-Hotels-Anesis-Hotel.h1516031.Hotel-Information), just 2 miles away. Kastoria Airport (KSO-Aristoteles) is closer at 7 miles from Mesopotamia, offering luxurious stays like [Limneon Resort & Spa](https://www.expedia.com/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information), a 5-star hotel 3 miles away, and [Orologopoulos Mansion](https://www.expedia.com/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information), also 5-star and 5 miles away. Hotels near Kastoria provide various transportation services, including free airport shuttles and on-request transfers, ensuring a smooth travel experience. ## Frequently asked questions ### What is the best area to stay in Mesopotamia? > This central area is where you'll find most of the town's amenities, including local shops, bakeries, and traditional tavernas. It's a convenient base for exploring the surrounding region, with easy access to roads leading to nearby attractions. Families appreciate this area for its practicality and the ease of finding essentials close by. > > > For those seeking a more tranquil experience, the residential streets just off the main road offer a quieter alternative. These areas provide a peaceful setting while still being within a short walk of the town center's conveniences. ### When is the best time to go to Mesopotamia? > During these months, you'll experience mild temperatures, typically ranging from the mid-60s to high 70s Fahrenheit (18-26°C), with less humidity and fewer crowds than the peak summer months. This makes it ideal for outdoor activities like hiking in the surrounding mountains or visiting local historical sites without the intense heat. Travelers looking for a relaxing trip with comfortable weather will find these periods particularly appealing. > > > For those interested in cultural events and local festivals, early autumn often features grape harvests and traditional celebrations, offering a unique insight into the region's heritage. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mesopotamia hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Mesopotamia hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Poria Hotels ](https://www.expedia.com/Poria-Hotels.d6335337.Travel-Guide-Hotels) - [Non-Smoking Hotels in Maniakoi ](https://www.expedia.com/Maniakoi-Hotels-Smoke-Free-Hotels.0-0-d3000702866-tSmokeFreeHotels.Travel-Guide-Filter-Hotels) - [Hotels near Kastoria Lake ](https://www.expedia.com/Kastoria-Lake-Hotels.0-l553248621532501791-0.Travel-Guide-Filter-Hotels) - [Kastoria Hotels ](https://www.expedia.com/Kastoria-Hotels.d1928.Travel-Guide-Hotels) - [Hotel Wedding Venues Hotels in Kastoria ](https://www.expedia.com/Kastoria-Hotels-Wedding-Hotels.0-0-d1928-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Kastoria ](https://www.expedia.com/Kastoria-Hotels-Hotels-With-Indoor-Pool.0-0-d1928-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - 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