Title: Mesopotamia Vacation Rentals from $105: Search Short-Term Rentals | Expedia.com

[Mesopotamia Travel Guide](https://expedia.com/Mesopotamia.dx6335336)[Hotels in Mesopotamia](https://expedia.com/Mesopotamia-Hotels.d6335336.Travel-Guide-Hotels)[Flights to Mesopotamia](https://expedia.com/Cheap-Flights-To-Mesopotamia.d6335336.Travel-Guide-Flights)[Car Rentals in Mesopotamia](https://expedia.com/Car-Rentals-In-Mesopotamia.d6335336.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.com/Mesopotamia.d6335336.Destination-Travel-Guides)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=6335336&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mesopotamia vacation rentals

![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/19dc8c61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/d3390b94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/c7834e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/eba32f9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anastasia s Kastoria Cozy Modern Garden Retreat

[](https://www.expedia.com/Kastoria-Hotels-Anastasia-S-Kastoria-Cozy-Modern-Garden-Retreat.h123532946.Hotel-Information)

Kastoria

$97 nightly

$111 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-Anastasia-S-Kastoria-Cozy-Modern-Garden-Retreat.h123532946.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/114000000/113780000/113780000/113779987/701e10b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/114000000/113780000/113780000/113779987/4176095c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/114000000/113780000/113780000/113779987/358b358a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/114000000/113780000/113780000/113779987/3e1ab0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The South Apartment in Old Town Kastoria

[](https://www.expedia.com/Kastoria-Hotels-The-South-Apartment-In-Old-Town-Kastoria.h113779987.Hotel-Information)

Kastoria

$158 nightly

$158 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-The-South-Apartment-In-Old-Town-Kastoria.h113779987.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/116000000/115110000/115106800/115106765/1965062a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/116000000/115110000/115106800/115106765/c8a592f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/116000000/115110000/115106800/115106765/7214b96a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115110000/115106800/115106765/3895543d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sweet Home Mitropoleos

[](https://www.expedia.com/Kastoria-Hotels-Sweet-Home-Mitropoleos.h115106765.Hotel-Information)

Kastoria

$105 nightly

$105 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-Sweet-Home-Mitropoleos.h115106765.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114480000/114477100/114477027/242d2977.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114480000/114477100/114477027/162535ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114480000/114477100/114477027/fd226351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114480000/114477100/114477027/5ad076a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Modern apartment with a lake view for a comfortable stay. Easy parking space

[](https://www.expedia.com/Kastoria-Hotels-Modern-Apartment-With-A-Lake-View-For-A-Comfortable-Stay-Easy-Parking-Space.h114477027.Hotel-Information)

KASTORIA

[](https://www.expedia.com/Kastoria-Hotels-Modern-Apartment-With-A-Lake-View-For-A-Comfortable-Stay-Easy-Parking-Space.h114477027.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/123000000/122570000/122563400/122563380/92c58e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/123000000/122570000/122563400/122563380/7a3fb754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/123000000/122570000/122563400/122563380/c299b1d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/123000000/122570000/122563400/122563380/2a02859f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Sunset Haven Kastoria – Modern Lake Elegance

[](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122563380.Hotel-Information)

Nea Lefki

$269 nightly

$287 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122563380.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/124000000/123510000/123507400/123507366/83c2a209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/124000000/123510000/123507400/123507366/2cab3180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123510000/123507400/123507366/fb7e8d1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/124000000/123510000/123507400/123507366/d2304f97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anastasia's Kastoria Cozy Modern Garden Retreat

[](https://www.expedia.com/Kastoria-Hotels-Anastasias-Kastoria-Cozy-Modern-Garden-Retreat.h123507366.Hotel-Information)

Maniaki

$94 nightly

$104 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-Anastasias-Kastoria-Cozy-Modern-Garden-Retreat.h123507366.Hotel-Information)

![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/da27481d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/43f9dc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/c8716788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/a411bbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Sunset Haven Kastoria Modern Lake Elegance

[](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information)

Kastoria

$280 nightly

$319 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25&regionId=6335336&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Private vacation homes

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Apartments

[](https://www.expedia.com/Hotel-Search?destination=Mesopotamia%2C+Kastoria%2C+Western+Macedonia%2C+Greece&regionId=6335336&latLong=40.50174%2C21.165957&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APARTMENT)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Mesopotamia%2C+Kastoria%2C+Western+Macedonia%2C+Greece&regionId=6335336&latLong=40.50174%2C21.165957&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VILLA)

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## Top Mesopotamia Hotel Reviews

![Limneon Resort & Spa](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/009cc717_y.jpg)

### Limneon Resort & Spa

10/10 Excellent

"This is an incredible hotel for families - child friendly, clean, and wonderful facilities. There is a small indoor play zone with someone who looks after the kids. The breakfast buffet is fantastic. The indoor pool is lovely. Everyone that works here is the kindest! My family and I had a wonderful stay "

[](https://expedia.com/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information)

![Guest House Ilektra](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/154a1dd3_y.jpg)

### Guest House Ilektra

10/10 Excellent

"Friendly and courteous hosts, great food and excellent service "

[](https://expedia.com/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information)

![Kyknos De Luxe Hotel](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/9ba540ac_y.jpg)

### Kyknos De Luxe Hotel

10/10 Excellent

"The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods"

[](https://expedia.com/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information)

![Orologopoulos Mansion](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/a88b51c3_y.jpg)

### Orologopoulos Mansion

10/10 Excellent

"Wonderful stay Very well kept hotel Nice room with a warm feeling The spaces in hotel are beautiful and give you the feeling that you stay at a luxurious home Very good breakfast- I will definitely stay here again "

[](https://expedia.com/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information)

![Esperos Palace Luxury & Spa Hotel](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/42ff45d8_y.jpg)

### Esperos Palace Luxury & Spa Hotel

10/10 Excellent

"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "

[](https://expedia.com/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information)

![The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη](https://images.trvl-media.com/lodging/35000000/34940000/34934000/34933999/7e2a3abb_y.jpg)

### The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη

10/10 Excellent

"Γουστόζικο, περιποιημένο, πεντακάθαρο σπίτι σε τέλεια τοποθεσία. Ησυχία με εύκολη πρόσβαση στην πόλη της Καστοριάς και άλλα αξιοθέατα."

[](https://expedia.com/Kastoria-Hotels-.h34933999.Hotel-Information)

![Calma Hotel & Spa](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/w6487h5400x7y9-009caa8e_y.jpg)

### Calma Hotel & Spa

10/10 Excellent

"Pleasant stay. Good amenities. Great staff. "

[](https://expedia.com/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information)

![Chloe Hotel](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/37147189_y.jpg)

### Chloe Hotel

10/10 Excellent

"Romantic and special. Highly recommend. Kastoria is a rare find. This hotel is a great getaway. "

[](https://expedia.com/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information)

![Hotel Anastassiou](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775_y.jpg)

### Hotel Anastassiou

8/10 Good

"Nice simple stay."

[](https://expedia.com/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information)

## Find out more about Mesopotamia

**Everything you need to know about Mesopotamia vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesopotamia vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesopotamia vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Mesopotamia vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Mesopotamia. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesopotamia in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $105 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Mesopotamia rentals**

At Expedia, we put the best Mesopotamia vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesopotamia rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesopotamia vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesopotamia. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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## Frequently asked questions

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- [Mövenpick Hotel Mactan Island Cebu](https://expedia.com/Lapu-Lapu-Hotels-Movenpick-Hotel-Mactan-Island-Cebu.h1192069.Hotel-Information)
- [Hotels in Mesolourion](https://expedia.com/Mesolourion-Hotels.d6335291.Travel-Guide-Hotels)
- [Comfort Suites Scranton near Montage Mountain](https://expedia.com/Scranton-Hotels-Comfort-Suites-Scranton-Near-Montage-Mountain.h62897.Hotel-Information)
- [Wichita Mountains Wildlife Refuge hotels](https://expedia.com/Wichita-Mountains-Wildlife-Refuge-Hotels.0-l6257769-0.Travel-Guide-Filter-Hotels)
- [Hotels in Varikon](https://expedia.com/Varikon-Hotels.d6335271.Travel-Guide-Hotels)
- [Hotels in Nymfaio](https://expedia.com/Nymfaio-Hotels.d6335267.Travel-Guide-Hotels)
- [Aston at the Executive Centre Hotel](https://expedia.com/Honolulu-Hotels-Aston-At-The-Executive-Centre-Hotel.h1851.Hotel-Information)
- [Hotels in Sedona](https://expedia.com/Sedona-Hotels.d6054771.Travel-Guide-Hotels)

Flights

- [Flights from Barcelona to Pamplona](https://expedia.com/lp/flights/bcn/pna/barcelona-to-pamplona)
- [Flights from Madinah to Dhaka](https://expedia.com/lp/flights/med/dac/madinah-to-dhaka)
- [Flights from Port-au-Prince to New York](https://expedia.com/lp/flights/pap/jfk/port-au-prince-to-new-york)
- [Flights from Edmonton to Orlando](https://expedia.com/lp/flights/yeg/mco/edmonton-to-orlando)

Cars

- [Car rentals in Jessup](https://expedia.com/Car-Rentals-In-Jessup.d6834.Car-Rental-Guide)
- [Right Cars Car Rentals In Aminteo](https://expedia.com/Right-Cars-Car-Rentals-In-Aminteo.d3000476507-c1070.Car-Rental-Guide-Suppliers)
- [Car rentals in Siatista](https://expedia.com/Car-Rentals-In-Siatista.d6335352.Car-Rental-Guide)
- [Car rentals in Aetos](https://expedia.com/Car-Rentals-In-Aetos.d6335261.Car-Rental-Guide)

Packages

- [Ptolemaida Vacation](https://expedia.com/Ptolemaida.d6335276.Destination-Travel-Guides)

General

- [Visit Lechovo](https://expedia.com/Lechovo.dx6335264)
- [Visit Aiani](https://expedia.com/Aiani.dx6335342)
- [Visit Lavda](https://expedia.com/Lavda.dx3000463532)
- [Visit Tsotilion](https://expedia.com/Tsotilion.dx6335353)
- [Visit Agios Germanos](https://expedia.com/Agios-Germanos.dx6335344)
- [Visit Brussels](https://expedia.com/Brussels.dx178241)

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