Mesopotamos Vacations from $675

Book a Hotel + Flight or Car together to unlock savings

Your Mesopotamos Vacation

Put together a custom vacation package to Mesopotamos and start looking forward to your next epic adventure. Consider staying in the neighborhood of Karpofora, which is good for views and nature, for a real taste of this unique city. During your trip to Mesopotamos, set aside some time for sightseeing. A popular place to begin exploring is Polilimnio Waterfalls. Expedia will help you escape your daily routine. Tailor your vacation to Mesopotamos to suit your style of travel, whatever that may be!

The Latest Mesopotamos vacation packages

Price found within the past 48 hours. Click for updated prices.

Finiki Plaza

$675

per person

Oct 18 - Oct 22

found 1 day ago

Roundtrip non-stop flight included

Tel Aviv (TLV) to Kalamata (KLX)

8.8/10 Excellent! (8 reviews)

Karalis City Hotel

$1,088

per person

Oct 18 - Oct 22

found 1 day ago

Roundtrip non-stop flight included

Tel Aviv (TLV) to Kalamata (KLX)

8.6/10 Excellent! (127 reviews)

Thank you to the wonderful staff. Mimika, Natasia, Ioanna and Lambra was professional and courteous. The rooms were clean and spacious. We would definitely return.

Reviewed on Aug 25, 2026

Anaxo Resort

$767

per person

Oct 18 - Oct 22

found 1 day ago

Roundtrip non-stop flight included

Tel Aviv (TLV) to Kalamata (KLX)

9.8/10 Exceptional! (132 reviews)

Hotel Lagouvardos Village

$774

per person

Oct 18 - Oct 22

found 1 day ago

Roundtrip non-stop flight included

Tel Aviv (TLV) to Kalamata (KLX)

10/10 Exceptional! (26 reviews)

Stayed here last year, very relaxed atmosphere

Reviewed on Jul 23, 2026

Villa Vager Mani

$1,761

per person

Oct 2 - Oct 4

found 1 day ago

Roundtrip flight included

Sacramento (SMF) to Kalamata (KLX)

9.6/10 Exceptional! (7 reviews)

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What to do in Mesopotamos

Kalamata Old Town & Kastraki: History,Sunset & Local Flavors

$67

per adult

Tasting Kalamata an Introduction to Local Greek Food

$84

per adult

See all activities in Mesopotamos

Mesopotamos Hotel Deals

The Westin Resort, Costa Navarino

Navarino Dunes Trifylia Peloponnese

$357 nightly

$422 total

Sep 9 - Sep 10

Total with taxes and fees

9.6/10 Exceptional! (507 reviews)

"I wish the iron in room had steam and better quality."

Reviewed on Aug 30, 2026

Grecotel Filoxenia Kalamata

Navarinou Street Kalamata Peloponnese

$316 nightly

$376 total

Sep 30 - Oct 1

Total with taxes and fees

The Romanos, a Luxury Collection Resort, Costa Navarino

Navarino Dunes, Costa Navarino Trifylia Peloponnese

$375 nightly

$444 total

Sep 9 - Sep 10

Total with taxes and fees

9.4/10 Exceptional! (161 reviews)

"Exceptional for kids"

Reviewed on Aug 21, 2026

See all 1,240 properties in Mesopotamos

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesopotamos Vacation Packages

Mesopotamos Essential Information

Language	Greek
Currency	Euros
Local Welcome	Ya su
Local Goodbye	Yiá sou
Closest Airport	Kalamata Intl. Airport (KLX)
Top Sights	Nestors Cave, Antonopouleio Museum of Pylos and Paleokastro

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Frequently asked questions

How much does a Mesopotamos vacation package cost?

You can snap up a vacation package to this destination from $675 on Expedia. However, how much your vacation to Mesopotamos costs will depend on factors like your hotel choice, length of stay and season.

What are the cheapest months to go to Mesopotamos?

If you'd like to snag a cheap Mesopotamos vacation package, consider planning a trip in October, November and December. You'll typically find better prices on flights and accommodations during these months — perfect for budget-conscious travelers.

How many days is enough for Mesopotamos?

With a well-planned itinerary, you can easily visit the main Mesopotamos attractions in a handful of days. But if you want to discover hidden gems or go on day trips, think about booking your Mesopotamos vacation for longer.

How to find the best Mesopotamos package deals?

Begin your search for a Mesopotamos package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the ideal Mesopotamos package deal straight away, just play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mesopotamos escape underway.

Is it cheaper to book a Mesopotamos vacation as a package?

You can enjoy significant savings on your Mesopotamos getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.

When to book a vacation package to Mesopotamos?

If you're considering a spontaneous Mesopotamos getaway, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can score amazing deals on your hotels and flights by booking well in advance.

Does Expedia offer Book Now, Pay Later Mesopotamos vacation packages?

If you're anything like us, you love going away but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Mesopotamos break over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.