Mesopotamos Vacations from $644

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Your Mesopotamos Vacation

Put together a custom vacation package to Mesopotamos and start looking forward to your next epic adventure. Consider staying in the neighborhood of Karpofora, which is good for views and nature, for a real taste of this unique city. During your trip to Mesopotamos, set aside some time for sightseeing. A popular place to begin exploring is Polilimnio Waterfalls. Expedia will help you escape your daily routine. Tailor your vacation to Mesopotamos to suit your style of travel, whatever that may be!

The Latest Mesopotamos vacation packages

Price found within the past 48 hours. Click for updated prices.
Messina Resort Hotel

Messina Resort Hotel

4 out of 5
Price was $729, price is now $644 per person
$644
per person
May 19 - May 22
found 22 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Kalamata (KLX)
7.8/10 Good! (23 reviews)
Very friendly staff, always in a god mood and pleasant. The breakfast was not very nice and I didn't find it to be well cooked. We were charged for our morning coffee because we wanted cold coffee.

Reviewed on Aug 8, 2021

100 Rizes Seaside Resort - Small Luxury Hotels of The World

100 Rizes Seaside Resort - Small Luxury Hotels of The World

4 out of 5
Price was $1,209, price is now $927 per person
$927
per person
May 19 - May 22
found 22 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Kalamata (KLX)
9.2/10 Wonderful! (58 reviews)
Beautiful and peaceful spot. Service and dinner food slightly haphazard for hotel of this quality. Magical spot for a relaxing holiday though.

Reviewed on Aug 8, 2025

Buka Sandy Beach

Buka Sandy Beach

4 out of 5
Price was $1,241, price is now $1,033 per person
$1,033
per person
Apr 12 - Apr 17
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Kalamata (KLX)
9.2/10 Wonderful! (9 reviews)
Breakfast buffet needed more variety

Reviewed on Oct 6, 2025

Karalis City Hotel

Karalis City Hotel

3 out of 5
Price was $936, price is now $826 per person
$826
per person
May 19 - May 22
found 22 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Kalamata (KLX)
8.6/10 Excellent! (112 reviews)
Great hotel, one of the better ones we’ve stayed at in Greece. Very friendly staff and service.

Reviewed on Sep 21, 2025

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Discover the most popular places to visit in Mesopotamos

Ancient Messene

You can find out about the history of Messini with a trip to Ancient Messene. Discover the area's mountain views and temples.

Ancient Messene

Polilimnio Waterfalls

Explore the great outdoors at Polilimnio Waterfalls, a lovely green space in Messini. Wander the seaside in this family-friendly area.

Polilimnio Waterfalls

What to do in Mesopotamos

From Kalamata: Day Trip Hike to Gialova Lagoon with Dinner

From Kalamata: Day Trip Hike to Gialova Lagoon with Dinner

$86
per adult
From Kalamata: Day Trip Hike to Gialova Lagoon with Dinner
From Kalamata: Rock Climbing in Lagada

From Kalamata: Rock Climbing in Lagada

$87
per adult
From Kalamata: Rock Climbing in Lagada
Tasting Kalamata an Introduction to Local Greek Food

Tasting Kalamata an Introduction to Local Greek Food

$85
per adult
Tasting Kalamata an Introduction to Local Greek Food
See all activities in Mesopotamos

Mesopotamos Hotel Deals

The Westin Resort, Costa Navarino

The Westin Resort, Costa Navarino

5 out of 5
Navarino Dunes Trifylia Peloponnese
$296 nightly
The price is $341 total per night from Mar 8 to Mar 9
$341 total
Mar 8 - Mar 9
Total with taxes and fees
9.6/10 Exceptional! (482 reviews)
Wonderful stay . Loved the breakfast a special thanks to Elena from Marias breakfast . Very helpful. A severe thunderstorm in the evening meant we had 4 power cuts but luckily we got power back soon.

Reviewed on Oct 30, 2025

The Westin Resort, Costa Navarino
Horizon Blu Boutique Hotel

Horizon Blu Boutique Hotel

5 out of 5
217, Navarinou Str. Kalamata Peloponnese
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $114 total per night from Mar 1 to Mar 2
$114 total
Mar 1 - Mar 2
Total with taxes and fees
9.4/10 Exceptional! (302 reviews)
Room was spotless.

Reviewed on Dec 2, 2025

Horizon Blu Boutique Hotel
Elysian Luxury Hotel & Spa

Elysian Luxury Hotel & Spa

5 out of 5
Synoikia Kordia Kalamata Peloponnese
$110 nightly
The price is $130 total per night from Mar 29 to Mar 30
$130 total
Mar 29 - Mar 30
Total with taxes and fees
9.6/10 Exceptional! (96 reviews)
Good hotel with very nice staff. Nice size rooms. Clean , comfortable bed. Great shower. Has ample parking. Food for dinner at restaurant was average. Breakfast buffet had cold and hot options ( to order).

Reviewed on Nov 11, 2025

Elysian Luxury Hotel & Spa
See all 1,106 properties in Mesopotamos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesopotamos Vacation Packages

Mesopotamos Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Closest Airport
Kalamata Intl. Airport (KLX)
Top Sights
Nestors Cave, Antonopouleio Museum of Pylos and Paleokastro

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Frequently asked questions

How much does a Mesopotamos vacation package cost?
You can snap up a vacation package to this destination from $644 on Expedia. However, how much your vacation to Mesopotamos costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Mesopotamos?
If you'd like to snag a cheap Mesopotamos vacation package, consider planning a trip in October, November and December. You'll typically find better prices on flights and accommodations during these months — perfect for budget-conscious travelers.
How many days is enough for Mesopotamos?
With a well-planned itinerary, you can easily visit the main Mesopotamos attractions in a handful of days. But if you want to discover hidden gems or go on day trips, think about booking your Mesopotamos vacation for longer.
How to find the best Mesopotamos package deals?
Begin your search for a Mesopotamos package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the ideal Mesopotamos package deal straight away, just play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mesopotamos escape underway.
Is it cheaper to book a Mesopotamos vacation as a package?
You can enjoy significant savings on your Mesopotamos getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Mesopotamos?
If you're considering a spontaneous Mesopotamos getaway, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can score amazing deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Mesopotamos vacation packages?
If you're anything like us, you love going away but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Mesopotamos break over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.