Midtown Vacations from $325

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Midtown Vacation

Experiencing all that Midtown has to offer is a cinch with a Midtown vacation package. Well known for its culture and more, this interesting neighborhood is calling your name. Your trip to Midtown wouldn't be complete without seeing big-name attractions nearby such as Memphis Zoo, Orpheum Theatre and Sun Studio. Whatever your dream Midtown vacation looks like, you can make it a reality with Expedia.

The Latest Midtown Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hu. Hotel
River Inn of Harbor Town
The Stallion
Memphis Riverline Hotel
Residence Inn by Marriott Memphis Downtown

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown

Midtown Hotel Deals

Holiday Inn Express Memphis Medical Center Midtown by IHG

Holiday Inn Express Memphis Medical Center Midtown by IHG

2.5 out of 5
1180 Union Ave Memphis TN
Fully refundable
$122 nightly
The price is $147 total per night from Nov 29 to Nov 30
$147 total
Nov 29 - Nov 30
Total with taxes and fees
8.4/10 Very Good! (1,000 reviews)
"Need coffee pot in room"

Reviewed on Nov 13, 2026

Holiday Inn Express Memphis Medical Center Midtown by IHG
Best Western Plus Gen X Inn

Best Western Plus Gen X Inn

2.5 out of 5
1177 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $105 total per night from Dec 6 to Dec 7
$105 total
Dec 6 - Dec 7
Total with taxes and fees
Best Western Plus Gen X Inn
The Memphian, a Tribute Portfolio Hotel

The Memphian, a Tribute Portfolio Hotel

3.5 out of 5
21 SOUTH COOPER STREET Memphis TN
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $236 total per night from Nov 29 to Nov 30
$236 total
Nov 29 - Nov 30
Total with taxes and fees
The Memphian, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Midtown attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.