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Aug 29 - Aug 30
Tomorrow
Aug 30 - Aug 31
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

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Our top choices for Mitilinii hotels

1. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
United States
Christine
$183 nightly
$218 total
Sep 27 - Sep 28
Total with taxes and fees
Doryssa Seaside Resort

2. Doryssa Lithos Hotel

Doryssa Lithos Hotel
Samos
United Kingdom
Victoria
Doryssa Lithos Hotel

3. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
United States
Michael
$154 nightly
$180 total
Sep 2 - Sep 3
Total with taxes and fees
Hydrele Beach Hotel

4. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
Germany
Artsem
$205 nightly
$242 total
Aug 30 - Aug 31
Total with taxes and fees
Proteas Blu Resort - Adults Only

5. Samos Bay Hotel

Samos Bay Hotel
Samos
United States
aurelia
$70 nightly
$83 total
Sep 29 - Sep 30
Total with taxes and fees
Samos Bay Hotel

6. Arion Hotel

Arion Hotel
Samos
Turkey
Anonymous traveler
Arion Hotel

7. Kalidon Beach Hotel

Kalidon Beach Hotel
Samos
United States
Patricia
$92 nightly
$104 total
Sep 20 - Sep 21
Total with taxes and fees
Kalidon Beach Hotel

8. Semeli Boutique Hotel

Semeli Boutique Hotel
Samos
Turkey
ruziye
$156 nightly
$171 total
Sep 1 - Sep 2
Total with taxes and fees
Semeli Boutique Hotel

9. ADAMANTIA HOTEL

ADAMANTIA HOTEL
Samos
$90 nightly
$101 total
Sep 25 - Sep 26
Total with taxes and fees
ADAMANTIA HOTEL

10. Hotel Aria

Hotel Aria
Samos
United States
Leland
$53 nightly
$61 total
Sep 24 - Sep 25
Total with taxes and fees
Hotel Aria

11. Anna Studios

Anna Studios
Samos
United Kingdom
Susan
$124 nightly
$138 total
Sep 16 - Sep 17
Total with taxes and fees
Anna Studios

12. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
Netherlands
Mika
$155 nightly
$182 total
Sep 27 - Sep 28
Total with taxes and fees
Doryssa Boutique Hotel

13. Armonia Bay Hotel

Armonia Bay Hotel
Samos
Canada
Penny
$206 nightly
$231 total
Sep 19 - Sep 20
Total with taxes and fees
Armonia Bay Hotel

14. Virginia Hotel

Virginia Hotel
Samos
United States
Osman
$144 nightly
$158 total
Sep 11 - Sep 12
Total with taxes and fees
Virginia Hotel

15. Scorpios Hotel & Suites

Scorpios Hotel & Suites
Samos
Mexico
Karla
$148 nightly
$168 total
Sep 11 - Sep 12
Total with taxes and fees
Scorpios Hotel & Suites

16. Grand View Villas

Grand View Villas
Samos
United States
Anthony Craig
$210 nightly
$233 total
Sep 27 - Sep 28
Total with taxes and fees
Grand View Villas

17. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
$301 nightly
$347 total
Sep 26 - Sep 27
Total with taxes and fees
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

18. Aegeon

Aegeon
Samos
Australia
Tracey
$76 nightly
$89 total
Sep 12 - Sep 13
Total with taxes and fees
Aegeon

19. Jasmine apartments

Jasmine apartments
Samos
Canada
Mumbi
$130 nightly
$145 total
Sep 11 - Sep 12
Total with taxes and fees
Jasmine apartments

20. Samos Blue Sea

Samos Blue Sea
Samos
Turkey
Canan
$83 nightly
$96 total
Sep 11 - Sep 12
Total with taxes and fees
Samos Blue Sea
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Stay near popular Mitilinii attractions

Paleontological Museum of Mitilini Samos

You can spend time exploring the galleries in Paleontological Museum of Mitilini Samos during your travels in Mitilinii. While you're in the area, stroll along the beautiful beaches.
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Natural History Museum of the Aegean

10.0/10 (1 review)
You can spend an afternoon studying the exhibits at Natural History Museum of the Aegean in Mitilinii. While you're in the area, stroll along the beautiful beaches.
See properties

Top Mitilinii Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

8/10 Good
"Very good, friendly place"
Zafer 3-night trip
Posted less than an hour ago
Doryssa Seaside Resort
Virginia Hotel

Virginia Hotel

8/10 Good
"Helpful staff, clean rooms, excellent views. Only downside parking is hard to find and the door separating two rooms doesnt do much for noise."
Osman 2-night trip
Posted 10 days ago
Virginia Hotel
Hydrele Beach Hotel

Hydrele Beach Hotel

10/10 Excellent
"Huge ocean view room with two bathrooms. Very professional and polite staff."
maria 4-night trip
Posted 13 days ago
Hydrele Beach Hotel
Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa

10/10 Excellent
"We really enjoyed our stay at the Samian Mare. The staff are so helpful and the the hotel is very contemporary in style and very clean. It’s in a great location across the road from the beach."
Kevin Michael 14-night trip
Posted 2 weeks ago
Samian Mare Hotel Suites & Spa
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

8/10 Good
"Inner architecture is not good, rooms are good and clean, staff are really nice and helpful. I bought sea view room but it was not that much sea view it was more like concrete view, Beach and pool side are quite nice Breakfast was very good"
ercan 1-night trip
Posted 2 weeks ago
Proteas Blu Resort - Adults Only
Ino Hotel & Suites

Ino Hotel & Suites

10/10 Excellent
"The hotel is renovated in 2024 its lication is very practical and has free parking.the staff is really nice"
antoine 7-night trip
Posted 3 weeks ago
Ino Hotel & Suites
Doryssa Boutique Hotel

Doryssa Boutique Hotel

10/10 Excellent
"The staff really make this hotel. Attentive, friendly and an absolute joy. Thank you for an amazing stay!"
Louise 3-night trip
Posted 1 month ago
Doryssa Boutique Hotel
Sirius House

Sirius House

10/10 Excellent
"great host, very clean and spacious place. brand new amenities. we love the location of Mytillini; since it is in the middle of the island."
Keriman 4-night trip
Posted 2 months ago
Sirius House
Doryssa Theorem Hotel

Doryssa Theorem Hotel

10/10 Excellent
"Nice and clean hotel in the heart of Pythagorio. Two minutes walk to beach, port, restaurants and famous cafe shops. No rental car needed is a big plus. Breakfast was looking good but we never had anything but a coffee. Bartender Iro was over and beyond with her service. If Samos is your destination and don’t want to move much, choose one of the doryssas from the chain (theorem or method if you would), you won’t regret it!"
Mehmet Serhan 2-night trip
Posted 2 months ago
Doryssa Theorem Hotel

More cheap stays in Mitilinii

Nepheli

Nepheli

Th Sofouli 10 Samos Samos Island
$58 nightly
$66 total
Sep 22 - Sep 23
Total with taxes and fees
8/10 Very Good! (16 reviews)
Nepheli
Mykali

Mykali

Pythagorion Samos North Aegean Islands
$74 nightly
$82 total
Sep 26 - Sep 27
Total with taxes and fees
Mykali
Kalidon Beach Hotel

Kalidon Beach Hotel

Kokkari Samos Samos Island
$92 nightly
$104 total
Sep 20 - Sep 21
Total with taxes and fees
9.6/10 Exceptional! (28 reviews)
Kalidon Beach Hotel
 Doryssa Lithos Hotel

Doryssa Lithos Hotel

Pythagorion Samos
Get rates Doryssa Lithos Hotel
Sunrise Hotel

Sunrise Hotel

Ireon Samos Samos Island
Get rates
8.8/10 Excellent! (49 reviews)
Sunrise Hotel
Glicorisa Beach

Glicorisa Beach

Pythagorio Samos Samos Island
Get rates
9.2/10 Wonderful! (27 reviews)
Glicorisa Beach

Frequently asked questions

What is the best area to stay in Mitilinii?
The best area to stay in Mitilini is the city center, particularly around the port and the main market streets, for its convenience and access to local life.This area is the heart of Mitilini, bustling with activity and offering easy access to shops, restaurants, and historical sites. The main street, Ermou, runs through the center, leading to the Port of Mitilini where ferries arrive and depart. The Castle of Mitilini stands prominently on a hill overlooking the city, providing a historical landmark.Couples will find this area ideal for a relaxed and engaging trip. You can enjoy strolls along the waterfront, dine at various tavernas, and easily explore historical sites like the Byzantine Museum or the Theophilos Museum, both within a short walk or drive. The central location means you're never far from a coffee shop or a place to enjoy the evening.For travelers looking for a comfortable base with easy access to amenities and transportation, staying near the port offers great advantages.
When is the best time to go to Mitilinii?
The best time to go to Mitilinii is during the shoulder seasons of May, early June, September, and early October. These months offer pleasant weather, fewer crowds, and a relaxed experience.During May and early June, the island is lush and green, and the temperatures are comfortable for exploring. You'll find the sea warm enough for swimming, and the main attractions, like the Mytilene Castle and the Archaeological Museum, are less crowded. This period is great for couples who enjoy scenic walks and discovering local culture without the peak season rush.September and early October also provide excellent conditions. The summer heat has subsided, but the sea remains warm for swimming. The olive harvest often begins in October, offering a unique cultural experience.
Where can I find the best nightlife in Mitilinii?
Mitilinii's nightlife is primarily concentrated in two main areas, offering different experiences.The waterfront promenade, particularly along the stretch near the port, is the center of evening activity. Here, you'll find numerous cafes that transform into bars as the evening progresses. Many of these establishments offer outdoor seating with views of the harbor. You'll find a mix of places playing popular Greek and international music, and some that are more focused on casual drinks and conversation.For a more traditional bar experience, the streets radiating from the main square (Plateia Sapfous) offer a selection of smaller bars and pubs. These often have a cozier indoor setting and sometimes feature live acoustic music or DJ sets.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mitilinii.
How much is the nightly rate at a Mitilinii hotel?
Prices for hotels in Mitilinii often vary, but you can find a great deal from $61 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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