Pythagorio Vacations from $694

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Your Pythagorio Vacation

Book a Pythagorio vacation package and focus on what counts — having some fun. This means no more planning stresses, just lots more time to uncover the best parts of this interesting city, such as its ancient history and coastal scenery. Make your trip to Pythagorio even more fun by going sightseeing. Pythagoreion, Samos Pythagorion Archaeological Museum and Glicorisa Beach are among the most popular attractions worth exploring. Don't put off exploring this city any longer. Your perfect Pythagorio vacation is just a few clicks away with Expedia.

The Latest Pythagorio vacation packages

Price found within the past 48 hours. Click for updated prices.
So Nice Hotel

So Nice Hotel

3 out of 5
Price was $830, price is now $694 per person
$694
per person
Oct 5 - Oct 11
found 16 hours ago
Roundtrip non-stop flight included
Manchester (MAN) to Samos (SMI)
9.4/10 Exceptional! (26 reviews)
The hotel rooms are very nice size. I had an efficiency kitchen in there that was fully equipped. Room service was fantastic.

Reviewed on Aug 27, 2024

Ino Hotel & Suites

Ino Hotel & Suites

3 out of 5
Price was $1,211, price is now $1,023 per person
$1,023
per person
Oct 5 - Oct 11
found 16 hours ago
Roundtrip non-stop flight included
Manchester (MAN) to Samos (SMI)
8.6/10 Excellent! (103 reviews)
The apartment was beautifully set up. The service was phenomenal.. they give you custom breakfast included. Super accommodating, especially when we had a late flight, they let us still use the amenities and leave our luggage at the hotel.

Reviewed on Aug 19, 2024

Casa Cook Samos

Casa Cook Samos

5 out of 5
Price was $1,431, price is now $1,258 per person
$1,258
per person
Oct 5 - Oct 11
found 16 hours ago
Roundtrip non-stop flight included
Manchester (MAN) to Samos (SMI)
9.4/10 Exceptional! (74 reviews)
Relaxing and clean.

Reviewed on Aug 20, 2025

Virginia Hotel

Virginia Hotel

3 out of 5
Price was $929, price is now $824 per person
$824
per person
Oct 5 - Oct 11
found 16 hours ago
Roundtrip non-stop flight included
Manchester (MAN) to Samos (SMI)
8.2/10 Very Good! (35 reviews)
The hotel was very inviting and comfortable. the views from the poolside balcony were absolutely beautiful and the staff went above and beyond. Sofia was extremely kind and helpful. We loved our stay here and it was a perfect spot to relax in Samos!

Reviewed on Jul 15, 2025

Oceanida Bay

Oceanida Bay

3 out of 5
Price was $825, price is now $740 per person
$740
per person
Oct 5 - Oct 11
found 16 hours ago
Roundtrip non-stop flight included
Manchester (MAN) to Samos (SMI)
5.6/10 (38 reviews)
Amazing experience. Owners made us feel at home. They were very attentive and respectful. Easy parking.

Reviewed on Jul 26, 2025

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Discover the most popular places to visit in Pythagorio

Pythagoreion

4.5/5(27 reviews)

Learn about the local history of Pythagorio when you spend time at Pythagoreion. Wander the beaches and seaside in the area.

Pythagoreion

Samos Pythagorion Archaeological Museum

5/5(2 reviews)

You can browse the exhibits at Samos Pythagorion Archaeological Museum, a museum with a storied past, during your travels to Pythagorio. Wander the beaches and seaside in the area.

Samos Pythagorion Archaeological Museum

Heraion of Samos

4/5(1 review)

Learn about the local history of Ireon when you take a trip to Heraion of Samos. Wander the beaches and seaside in the area.

Heraion of Samos

What to do in Pythagorio

Samos Picnic Tour Relaxed Adventure

Samos Picnic Tour Relaxed Adventure

$35
per adult
Samos Picnic Tour Relaxed Adventure
Full Day Island Tour Discover Samos

Full Day Island Tour Discover Samos

$81
per adult
Full Day Island Tour Discover Samos
Athens Riviera Evening Cruise with Music and Swimming

Athens Riviera Evening Cruise with Music and Swimming

$69
per adult
Athens Riviera Evening Cruise with Music and Swimming
See all activities in Pythagorio

Pythagorio Hotel Deals

Casa Cook Samos

Casa Cook Samos

5 out of 5
Potokaki, Pythagorion, Samos
$305 nightly
The price is $351 total per night from Sep 23 to Sep 24
$351 total
Sep 23 - Sep 24
Total with taxes and fees
9.4/10 Exceptional! (78 reviews)
"Relaxing and clean."

Reviewed on Aug 20, 2025

Casa Cook Samos
Doryssa Seaside Resort

Doryssa Seaside Resort

5 out of 5
Pythagoreiou-Choras, Samos, Samos Island
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $250 total per night from Sep 8 to Sep 9
$250 total
Sep 8 - Sep 9
Total with taxes and fees
8.4/10 Very Good! (139 reviews)
Clean and comfortable
"Only really used the hotel for getting ready and to sleep, so can’t really comment too much. Hotel was comfortable and clean. Breakfast was good and it has a nice pool area with big comfy sunbeds. We were only there for 3 days, so spent most of our time sightseeing."

Reviewed on Jun 28, 2025

Doryssa Seaside Resort
Hydrele Beach Hotel

Hydrele Beach Hotel

4 out of 5
Potokaki beach, Pythagorion, Samos, Samos island
$164 nightly
The price is $191 total per night from Sep 1 to Sep 2
$191 total
Sep 1 - Sep 2
Total with taxes and fees
8.6/10 Excellent! (32 reviews)
"Great choice for a 4 star property."

Reviewed on Jul 2, 2025

Hydrele Beach Hotel
See all 304 properties in Pythagorio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Pythagorio Beach Vacation

Listen to the sound of waves crashing onto the shore and look out over the shimmering waters during your Pythagorio vacation. If you need a break from everyday life, a trip to Pythagorio will work wonders. We have a great range of Pythagorio vacation packages to pick from. Lock in one near Glicorisa Beach, just 1 mile from the downtown area, and live out your vacation fantasies without hurting your budget.

Things You Should Know About Pythagorio

  • Book one of our Pythagorio beach hotels to appreciate this destination at its very best. Dip a toe in the water and watch some gorgeous sunsets just steps from your front door.
  • Take a look at Hotel Katerina - Top Seaview Studio Potokaki and Nisea Hotel Samos. These quality hotels could just be ideal for your stay in Pythagorio.
  • Approximately 1,250 people live in Pythagorio. If you want advice about things to see and do, why not strike up a conversation with some of the friendly locals? Our Pythagorio things to do page is also a great source of info.
  • Glicorisa Beach, Panagia Spiliani Monastery and Monastery of Panagia Spiliani are some great attractions that should be on your travel agenda. With our Pythagorio vacation deals, you'll have more money in your back pocket to explore.

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Frequently asked questions

How much does a Pythagorio vacation package cost?
You can pick up a vacation package to this top destination from $694 on Expedia. However, how much your vacation to Pythagorio costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Pythagorio?
If you're hoping to book a cheap Pythagorio vacation package, consider traveling in January, March and November. You'll usually find lower prices on hotels and airfares during these months — ideal for budget-conscious travelers.
How many days is enough for Pythagorio?
Usually, a handful of days is enough to check out the top sights during your Pythagorio vacation. However, if you prefer to have some time to chill out or go on day trips, consider extending your itinerary.
Is it worth booking a vacation package to Pythagorio?
Pythagorio offers everything you need for a wonderful escape. Begin your Pythagorio vacation on a high note by visiting major attractions like Samos Pythagorion Archaeological Museum.
How to find the best Pythagorio package deals?
Begin your search for a Pythagorio package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the ideal Pythagorio package deal right away, simply tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Pythagorio getaway off to a flying start.
Is it cheaper to book a Pythagorio vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking stays and flights individually. Better still, you can personalize your Pythagorio trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Pythagorio?
If you've got your Pythagorio vacation dates finalized, book as soon as you can to grab some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are ideal for quick escapes.
How to plan a trip to Pythagorio?

  1. Choose the right time to travel: Your schedule, favorite season and the type of weather you enjoy can all influence your decision on when to travel to Pythagorio.
  2. Set your budget: Factor in costs like flights, transportation and food when working out how much to put aside for your trip to Pythagorio. Then, pick a hotel that matches your budget, whether that's a wallet-friendly stay or a deluxe retreat.
  3. Use our trip planning tool to discover Pythagorio: Research every aspect of your trip to Pythagorio with this comprehensive planner. Invite your friends and family to collaborate on a group trip, search for stays or things to do and make bookings.
  4. Decide your trip length: Consider how much time you want to spend exploring Pythagorio. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  5. Combine your airfare and accommodations: Once you've nailed down your dates and duration, lock in the ideal Pythagorio vacation package for you.
  6. Book any activities or day trips: Here's the fun part — locking in everything you want to see and do. Browse some of the incredible things to do in Pythagorio in Pythagorio and reserve your tickets early to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later Pythagorio vacation packages?
Jet off on your perfect trip to Pythagorio with our Book Now, Pay Later vacations. No need to scrimp and save or hold off until your next payday — we've partnered with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans mean you can spread the total cost across 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily budget for your trip and snap up travel deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.