Murphy Vacation Rentals

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Our top choices for Murphy vacation rentals

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
$123 nightly
The price is $144
Jan 4 - Jan 5, 2026
Total with taxes and fees
White House at Grand Central

The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles Historic District
10.0 out of 10, Exceptional, (136)
"We loved staying here in this adorable clean house that was only 1 block off of downtown Main Street shopping. "
United States
Lisa S.
The St. Charles Guest House, lovely historic home, fun for families and groups

Value Suites Extended Stay - St Louis

Value Suites Extended Stay - St Louis
3.0 star property
Maryland Heights
7.0 out of 10, Good, (1110)
"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."
United States
Timothy
$453 nightly
The price is $525
Dec 14 - Dec 15
Total with taxes and fees
Value Suites Extended Stay - St Louis

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (160)
"Very clean, check in was easy, great neighborhood with lots of food close. "
United States
Laura H.
$132 nightly
The price is $134
Dec 14 - Dec 15
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (102)
"Check-in was easy and the house was lovely "
United States
Delfino A.
$333 nightly
The price is $340
Dec 23 - Dec 24
Total with taxes and fees
Stunning 1890's Home - Sleeps 8!

Luxury 2BEDROOM LOFT near Bush Stadium

Luxury 2BEDROOM LOFT near Bush Stadium
Downtown St. Louis
9.4 out of 10, Exceptional, (6)
"The location was perfect to access all things Downtown! The space was clean and well furnished. Check in/out was a breeze and the included parking spot was a huge plus for us! Great place to stay! "
United States
Kelci Y.
Luxury 2BEDROOM LOFT near Bush Stadium

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
St. Charles Historic District
10.0 out of 10, Exceptional, (211)
"Nice view of the Mississippi in the morning. Just off of the main street in old town St Charles, this place was perfect for our needs."
United States
Ralph
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

Cozy Clark Suite in Frenchtown Saint Charles

Cozy Clark Suite in Frenchtown Saint Charles
St. Charles Historic District
9.6 out of 10, Exceptional, (14)
"Awesome place to stay"
United States
paul
Cozy Clark Suite in Frenchtown Saint Charles

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (134)
"This was such a cute historical home and was perfect for our weekend in St Charles!"
United States
Isabelle C.
$251 nightly
The price is $251
Dec 14 - Dec 15
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

Honky Tonk Hideaway

Honky Tonk Hideaway
St. Charles Historic District
8.8 out of 10, Excellent, (12)
"Great location close to historic district."
United States
Hugh S.
$288 nightly
The price is $294
Dec 14 - Dec 15
Total with taxes and fees
Honky Tonk Hideaway

Home Near Main Street-Covered Patio-Hot Tub!

Home Near Main Street-Covered Patio-Hot Tub!
Saint Charles
9.8 out of 10, Exceptional, (26)
"The place was great! "
United States
Melissa I.
$443 nightly
The price is $452
Dec 15 - Dec 16
Total with taxes and fees
Home Near Main Street-Covered Patio-Hot Tub!

Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St
St. Charles Historic District
8.6 out of 10, Excellent, (14)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
$209 nightly
The price is $235
Dec 14 - Dec 15
Total with taxes and fees
Madison House 1 -Walk to Main St

Tamm Ave 3-BR Retreat

Tamm Ave 3-BR Retreat
Dogtown
9.6 out of 10, Exceptional, (48)
"We enjoyed are stay at this house. It was very clean and comfortable. Host was very quick to respond and easy check in. Nice neighborhood, felt very safe. Would for sure stay here again!!"
United States
Cindy A.
Tamm Ave 3-BR Retreat

Stylish South City King 1BR Apt

Stylish South City King 1BR Apt
2.0 star property
Marine Villa
10.0 out of 10, Exceptional, (9)
"Great location, great accommodations, great host."
United States
Scott W.
$165 nightly
The price is $179
Dec 14 - Dec 15
Total with taxes and fees
Stylish South City King 1BR Apt

Residence on the Roundabout

Residence on the Roundabout
St Charles
9.4 out of 10, Exceptional, (145)
"House was very nice. Pictures were good and we knew what to expect. Location was great for where we wanted to go.Owner was punctual when we had any questions!"
United States
Anne L.
Residence on the Roundabout

StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.

StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.
Southwest Garden
10.0 out of 10, Exceptional, (288)
"A comfortable stay in a wonderful neighborhood. This location was great and allowed us to visit all the places we planned. It was very clean and well stocked "
United States
Karen F.
$145 nightly
The price is $159
Dec 14 - Dec 15
Total with taxes and fees
StL's ‘The Hill' NBHD. Famous for all things Italian. Cozy & clean 2nd fl apt.

Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (136)
"Very cute property in historic neighborhood. We enjoyed our stay!"
United States
Jo L.
$136 nightly
The price is $159
Dec 15 - Dec 16
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!

The Otter Suite at Divine Otter

The Otter Suite at Divine Otter
St. Charles Historic District
9.0 out of 10, Wonderful, (7)
"We absolutely loved this place! I would recommend this place. We had one issue but it was resolved. If you have children, I would probably stay somewhere else. There are bars all around and gets loud at night but it does get really quiet after 1:30 a.m. The property manager was absolutely amazing and is very quick to respond to your needs. "
United States
kim F.
The Otter Suite at Divine Otter

Brand New! Soulard Charmer - Pet Friendly.

Brand New! Soulard Charmer - Pet Friendly.
Soulard
9.6 out of 10, Exceptional, (24)
"This house was beautiful and in a very nice spot in St. Louis. Close to everything and the hosts were amazing. Would definitely use again "
United States
Justin B.
$261 nightly
The price is $261
Dec 14 - Dec 15
Total with taxes and fees
Brand New! Soulard Charmer - Pet Friendly.

Spacious 2 BR Balcony Hideaway

Spacious 2 BR Balcony Hideaway
Northampton
8.0 out of 10, Very Good, (15)
"Great stay! Management was easy to reach and very helpful when we couldnt find the correct wifi network. Nice place, would stay again."
United States
Bob C.
Spacious 2 BR Balcony Hideaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Murphy Hotel Reviews

Find out more about Murphy

Everything you need to know about Murphy vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Murphy vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Murphy vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Murphy vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Murphy. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Murphy in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $134 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Murphy rentals

At Expedia, we put the best Murphy vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Murphy rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Murphy vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Murphy. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Murphy?

Yes, we give you a choice of vacation rentals close to well known sights in Murphy, or you can go with a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Murphy has to offer?

Stunning 1890's Home - Sleeps 8! : Visitors like this Murphy vacation home rental. It is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Murphy?

While exploring the area, visit family-friendly sights like Magic House - St. Louis Children's Museum, or get outside and enjoy nature at Lone Elk Park. In the larger area, you’ll find Castlewood State Park and Route 66 State Park.

What’s a vacation rental in Murphy like?

Vacation rentals are private properties where you can stay for a couple of days or more in Murphy. Vacation rentals offer amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a vacation rental can provide a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a small group gathering.